Clinical trials: Polyethylene Glycol
Polyps, Colon Preparation
Comparison Between Asymmetric And Standard Split-Dose Regimen For Bowel Preparation
We aimed to compare the efficacy for bowel cleansing of a split-dose regimen with a low morning dose of PEG solution (Asymmetric; 25% of the dose is given on the day of the procedure and 75% of the dose is given on the day…
- Trial name
- NCT03146052
- Testing
- PEG-4000 added with citrates and simethicone (PEG-CS) plus Bisacodyl
- Where
- Italy
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- ASST Rhodense
Healthy
Evaluate the Pharmacokinetics of Warfarin When Coadministered With PEX168 in Healthy Adult Subjects
To assess the effect of PEX168 doses on the pharmacokinetics of warfarin in healthy subjects.To provide a scientific basis for clinical drug combination of PEX168.
- Trial name
- NCT02461914
- Testing
- PEX168, Warfarin
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Ulcerative Colitis
Tolerability and Efficacy of Sodium Picosulfate/Magnesium Citrate Versus PEG/Ascorbic Acid in Ulcerative Colitis Patients
Ulcerative colitis is a chronic condition that results in the inflammation of the colon and rectum. Patients suspected to have ulcerative colitis are diagnosed via colonoscopy.
- Trial name
- NCT03581149
- Testing
- Sodium Picosulfate/Magnesium Citrate Laxative, 2L polyethylene glycol/ascorbic acid
- Where
- Lebanon
- Volunteers
- 68 people
- Sponsor
- American University of Beirut Medical Center
Hemolytic Uremic Syndrome, Hemorrhagic Colitis
Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic Colitis
The investigators examined the outcome of patients with severe Enterohaemorrhagic E. Coli (EHEC) O104:H4 infection suffering from bloody diarrhoea that were at risk to develop hemolytic uremic syndrome and underwent repetitive…
- Conditions
- Hemolytic Uremic Syndrome, Hemorrhagic Colitis, Intestinal Infectious Disease, Intestinal Infection Due to E. Coli
- Trial name
- EHEC-PEG (NCT01561248)
- Testing
- polyethylene glycol solution for daily bowel lavage.
- Where
- Germany
- Volunteers
- 33 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Colonic Adenoma, Bowel Preparation
Efficacy of Split-dose of Oral MMS for Bowel Preparation in Elderly Patients
Adequate bowel preparation is critical for successful colonoscopy and a large volume of PEG was required for bowel preparation in patients undergoing colonoscopy.
- Trial name
- NCT04948567
- Testing
- split-dose of Magnesium Sulfate solution, split-dose of PEG
- Where
- 2 sites in China
- Volunteers
- 1,174 people
- Sponsor
- Air Force Military Medical University, China
Type 2 Diabetes
A PK/PD Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes
Polyethylene Glycol Loxenatide (PEX168) is a new human glucagon-like peptide 1 (GLP-1) analogue that created on the basis of the Exenatide and modified by polyethylene glycol (PEG).
- Trial name
- NCT01965509
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Bowel Preparation Before Colonoscopy
Improved Bowel Preparation Method for Colonoscopy Based on Different Risk Stratification
The purpose of this study is to evaluate the efficacy of polyethylene glycol（PEG） combined with lactulose for bowel preparation before colonoscopy in low-risk patients and high-risk patients.
- Trial name
- NCT04582942
- Testing
- PEG, PEG+lactulose
- Where
- China
- Volunteers
- 2,028 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Type 2 Diabetes
A Phase I Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes
Polyethylene Glycol Loxenatide (PEX168) is a new human glucagon-like peptide 1 (GLP-1) analogue that created on the basis of the Exenatide and modified by polyethylene glycol (PEG).
- Trial name
- NCT01965496
- Testing
- PEX168
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Dry Eye
Bilateral, Masked Comparison of PEG-400 Based Artificial Tear and Systane for the Treatment of Dry Eye Signs, Symptoms and Visual Quality
To evaluate and compare the effects of PEG-400 based artificial tear and Systane tears in mild-moderate dry eye patients. TBUT, Visual impact and subjective evaluations will be assessed in this month long trial.
- Trial name
- NCT00622037
- Testing
- PEG-400 based artificial tear, Systane
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Constipation
Comparator Study of PEG 3350 Versus Prucalopride in Females With Chronic Constipation
This study is to compare the efficacy and safety of polyethylene glycol (PEG) 3350 with that of prucalopride in the treatment of chronic constipation in females.
- Trial name
- NCT01251822
- Testing
- PEG 3350 plus electrolytes, Prucalopride
- Where
- Romania
- Volunteers
- 240 people
- Sponsor
- Norgine
Diabetic Complication, Covid19 Virus Infection
Suspicion of Hypoglycemic Effect of mRNA Based Covid-19 Vaccines (Polyethylene Glycol) Will Happen , Observational Study on Diabetic Patients at Saudia Arabia
vaccines for covid-19 are gold strategy and great achievement at this century for protection against complications of covid-19 , development of many vaccines with different technology represent a big challenge for this disease so…
- Conditions
- Diabetic Complication, Covid19 Virus Infection, Hypoglycemia, Polyethylene Glycol Adverse Reaction
- Trial name
- NCT05087225
- Testing
- polyethelyene glycol
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
Lymphoma, Non-Hodgkin;Hodgkin Disease
Clinical Application of Polyethylene Glycol Liposome Doxorubicin (PLD) in Primary Lymphoma
Anthracyclines were basic drugs in lymphoma treatment. However, their dose accumulation related cardiac toxicity limits their clinical application, especially adriamycin. Adriamycin has been gradually replaced by epirubicin.
- Trial name
- NCT02526823
- Testing
- R-CHOP/CHOPE or ABVD chemotherapy regimen, R-CDOP/CDOPE or DBVD chemotherapy regimen
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Shandong Provincial Hospital
Colorectal Neoplasms, Diverticulitis
Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery
This randomized clinical trial studies how well neomycin and metronidazole hydrochloride with or without polyethylene glycol work in reducing infection in patients undergoing elective colorectal surgery.
- Conditions
- Colorectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases, Surgical Site Infection
- Trial name
- NCT03042091
- Testing
- Polyethylene Glycol, Neomycin, Metronidazole Hydrochloride
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Thomas Jefferson University
Bowel Preparation for Colonoscopy
Comparison of Two Methods of Bowel Preparation for Colonoscopy in Hospitalized Patients
Morning-only colonoscopy preparation may improve efficiency by allowing same-day patient preparation and colonoscopy. The aim of the investigators study is to compare the efficacy and tolerability of morning-only Polyethylene…
- Trial name
- NCT01765491
- Testing
- Split-dose polyethylene glycol, Morning-only polyethylene glycol
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Cook County Health
Kidney Transplantation, Anemia
Correcting Anemia and Native Vitamin D Supplementation in Kidney Transplant Recipients
The purpose of this study is to evaluate the effect of anemia correction and vitamin D supplementation in kidney transplant recipients.
- Conditions
- Kidney Transplantation, Anemia, Vitamin D Deficiency, Renal Insufficiency, Chronic
- Trial name
- CANDLE-KIT (NCT01817699)
- Testing
- High Hb target, cholecalciferol
- Where
- Japan
- Volunteers
- 161 people
- Sponsor
- CANDLE-KIT Trial Study Group
Acute Kidney Injury
Renal Safety of Bowel Preparation With Polyethylene Glycol
This study evaluates the changes of renal function after taking bowel cleansing agent polyethylene glycol for elective colonoscopy.
- Trial name
- NCT02657564
- Testing
- Polyethylene glycol (PEG)
- Where
- Taiwan
- Volunteers
- 1,237 people
- Sponsor
- Evergreen General Hospital, Taiwan
Indication for Modification of Patient Status (Diagnosis)
Colon Preparation With 2L PEG in Combination With Lubiprostone vs 4L PEG
Colonoscopy is the current standard method for examination of the colon. Bowel cleansing prior to colonoscopy is the essential prerequisite to ensure complete mucosal visualization and lesion identification.(1,2) Suboptimal…
- Trial name
- NCT04138004
- Testing
- polyethylene glycol in combination with lubiprostone, polyethylene glycol alone
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Split-dose Bowel Preparation, Polyethylene Glycol Solution
Individual Approach for Bowel Preparation Before Colonoscopy
This is a prospective, randomized, single-blind study designed to evaluate the influence of individual approach on bowel preparation quality for colonoscopy.
- Conditions
- Split-dose Bowel Preparation, Polyethylene Glycol Solution, Risk Factors Inadequate Preparation
- Trial name
- NCT01476735
- Testing
- individual preparation for colonoscopy
- Where
- Poland
- Volunteers
- 266 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Healthy
Safety of Total Daily Doses of Polyethylene Glycol (PEG) 400 Administered Orally to Healthy Male Human Subjects
To assess the safety and tolerance of 5 mL to 20 mL PEG 400 in multiple rising doses
- Trial name
- NCT02260076
- Testing
- PEG 400
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Bowel Preparation
Efficacy and Safety of Polyethylene Glycol Compared With Sodium Picosulphate for Bowel Preparation Before Colonoscopy
Patients intended for ambulatory colonoscopy will be randomized into 2 groups
- Trial name
- NCT01093274
- Testing
- Sodium Picosulphate, Polyethylene Glycol
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center