Clinical trials: Polyethylene Glycol Solution
Colonoscopy Preparation
Bowel Preparation for Colonoscopy in Children
The primary objective of this study is to determine whether Miralax results in a more efficacious preparation as compared to senna for pediatric colonoscopy.
- Trial name
- NCT01140295
- Testing
- polyethylene glycol, senna
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Children's Hospital of Philadelphia
Colonoscopy, Bowel Preparation Solutions
Electrolyte Beverage Combined With Polyethylene Glycol for Colonoscopy Bowel Preparation
This randomized controlled trial aims to evaluate the effects of different ratios of electrolyte beverage and water combined with polyethylene glycol (PEG) on bowel preparation quality before colonoscopy.
- Conditions
- Colonoscopy, Bowel Preparation Solutions, Colorectal Cancer Screening
- Trial name
- NCT07608120
- Testing
- PEG With Water, PEG With Low-dose Electrolyte Beverage, PEG With Medium-dose Electrolyte Beverage
- Where
- China
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Colonoscopy
Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor Screening
To compare the efficacy, acceptability and safety of the new 2 liter gut cleansing solution (Moviprep) and NaP preparation in routine colon cleansing prior to tumor screening colonoscopies
- Trial name
- NCT00427089
- Testing
- Macrogol 3350 Na sulphate NaCl KCl Ascorbic Acid Na Ascorbate, Sodium Phosphate solution (NaP)
- Where
- 12 sites in Germany
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Norgine
Healthy
Safety, Tolerance, and Pharmacokinetics of BILN 2061 ZW in Healthy Male Subjects, Combined With Preliminary Evaluation of Food Effect
To assess the safety, tolerance and pharmacokinetics of 5 mg to 2400 mg BILN 2061 ZW 1. In rising single doses 2. With and without a 64 g fat breakfast at one selected dose
- Trial name
- NCT02268760
- Testing
- BILN 2061 ZW single rising doses, BILN 2061 ZW fixed dose, Standardized breakfast
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Colonoscopy
Comparison Between OSS and 2L PEG/Asc for Bowel Preparation of Elderly People
For evaluation of the usefulness of oral sulfate solution (OSS) for bowel preparation of elderly people, investigators compare the efficacy, tolerability and safety between OSS and 2L polyethylene glycol (PEG) with ascorbic acid…
- Trial name
- NCT03520361
- Testing
- Oral sulfate solution (OSS), 2L PEG/Asc
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- KangWon National University Hospital
Bowel Preparation, Colonoscopy
Impact of Time Intervals of Preparation on Quality and Tolerance of the Bowel Preparation
The purpose of this study is to determine optimal time intervals for preparation before colonoscopy using different formulas.
- Trial name
- NCT02908919
- Testing
- Colonoscopy
- Where
- 2 sites in Czechia
- Volunteers
- 480 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Colonoscopy
Investigation of PICOPREP and PEG-ELS for Bowel Preparation for Colonoscopy
Eligible subjects undergoing a colonoscopy will randomly receive either PICOPREP or polyethylene glycol 4000 electrolyte lavage solution before the procedure to evaluate its effectiveness, tolerability and safety.
- Trial name
- NCT01356407
- Testing
- PICOPREP, PEG-ELS
- Where
- 7 sites in China
- Volunteers
- 300 people
- Sponsor
- Ferring Pharmaceuticals
Hyponatremia
Incidence of Hyponatremia in PEG-SD Compared to PEG-ELS
Objective: To compare the incidence of peri-colonoscopy hyponatremia associated with PEG 3350 + sports drink (PEG-SD) versus PEG 3350-electrolyte solution + sodium sulfate + sodium ascorbate and ascorbic acid (PEG-ELS).
- Trial name
- NCT01299779
- Testing
- PEG-SD, PEG-ELS
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Thomas Jefferson University
Constipation
Comparison of PEG Solutions With and Without Electrolytes in the Treatment of Constipation
The aim of the study is to show that new polyethylene glycol (PEG) solution without electrolytes is as effective in the treatment of constipation as PEG solution with electrolytes in the elderly institutionalized people.
- Trial name
- PEGorion (NCT00603681)
- Testing
- Polyethylene glycol 4000, Polyethylene glycol 4000 with electrolytes
- Where
- 10 sites in Finland
- Volunteers
- 67 people
- Sponsor
- Orion Corporation, Orion Pharma
Cathartic Colon
Oral Sulfate Solution (SUPREP) Versus Polyethylene Glycol (PEG) Plus Ascorbic Acid
The aims of the present study is to compare oral sulfate solution (OSS) with low-dose polyethylene glycol plus ascorbic acid (2-L PEG/Asc) for bowel cleansing efficacy.
- Trial name
- NCT02761213
- Testing
- Oral sulfate solution (OSS), 2-L PEG/Asc
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bo-In Lee
Colonoscopy
Amitiza® Plus GoLYTELY® (PEG) Versus Placebo Plus GoLYTELY® for Outpatient Colonoscopy Preparation
The primary objective is to compare the effectiveness and tolerance of the medication named lubiprostone plus a large volume liquid laxative versus placebo which is a look alike medication that has no effect such as a sugar pill…
- Trial name
- PEG (NCT00645801)
- Testing
- lubiprostone (Amitiza)
- Where
- 3 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Colonoscopy
Polyethylene Glycol Versus Low Volume Solutions Prior to Colonoscopy
Study evaluates the efficacy and tolerability of low volume preparations compared with conventional 4L polyethylene glycol prior to colonoscopy
- Trial name
- NCT02956057
- Testing
- Polyethylene Glycols, Natrium picosulfate / Magnesium citrate, Polyethylene glycol / Ascorbic acid
- Where
- Czechia
- Volunteers
- 1,044 people
- Sponsor
- Tomas Bata Hospital, Czech Republic
Colonoscopy, Colon Polyp
The Effect of 1L Polyethylene Glycol Plus Ascorbic Acid With Prepackaged Low-Residue Diet for Bowel Preparation
Background 2L polyethylene glycol plus ascorbic acid (PEGA) is known to be as effective as standard 4L polyethylene glycol for bowel preparation. However, the volume of this regimen is still large.
- Conditions
- Colonoscopy, Colon Polyp, Bowel Preparation Solutions
- Trial name
- NCT03329339
- Testing
- 1 L PEG with ascorbic acid with prepackaged, low residue diet
- Volunteers
- 200 people
- Sponsor
- Seoul National University Bundang Hospital
Healthy
Single Rising Dose Study of BI 201335 ZW in Healthy Male Subjects
The objective of the current study is to investigate safety, tolerability, and pharmacokinetics of BI 201335 ZW following administration of single rising doses from 5 mg to 1500 mg.
- Trial name
- NCT02182271
- Testing
- BI 201335 ZW - single rising dose
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Bowel Preparation Solutions, Colonoscopy
Efficacy, Tolerance and Safety of Split Dose Bowel Preparation for Colonoscopy: 4L Polyethylene Glycol (PEG) Versus 1L Polyethylene Glycol Plus Sodium Picosulfate-magnesium Citrate (SPMC)
4L split dose PEG is the gold standard for bowel preparation, however it comes with poor tolerability and poor compliance. Combination of PEG with different agent is useful in reducing total volume, improving compliance and…
- Trial name
- NCT04474002
- Testing
- 4L Klean Prep®, 1L Klean prep® and 2 sachets Picoprep®
- Where
- Hong Kong
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Stasis; Colon
Comparison Between Coolprep and Picolyte for Bowel Cleansing
The investigators will compare with PEG+ascorbic acid and picosulfate+magnesium citrate about bowel preparation, patient's satisfaction, side effects to identify effectiveness of new bowel preparation drug.
- Trial name
- NCT01774175
- Volunteers
- 250 people
- Sponsor
- Gachon University Gil Medical Center
Colonoscopy
Comparison of Different Low Volume Solutions Prior to Colonoscopy
Study evaluates the head -to-head efficacy and tolerability of low volume preparations prior to colonoscopy
- Trial name
- NCT03698474
- Testing
- Natrium picosulfate / Magnesium citrate, Polyethylene glycol / Ascorbic acid, Natrium/ Kalium/ Magnesium sulfate
- Where
- Czechia
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Healthy
Safety, Pharmacokinetics, and Pharmacodynamics of BIRT 2584 XX in Healthy Male Volunteers
To assess safety, tolerability, pharmacokinetics, and pharmacodynamics of BIRT 2584 XX in single rising oral doses of 5 mg to 700 mg in a polyethylene glycol 400 (PEG 400) solution in healthy subjects
- Trial name
- NCT02259894
- Testing
- BIRT 2584 XX
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Bowel Preparation, Colonoscopy
Bowel Preparation for Colonoscopy in the Elderly
The success of colonoscopy is closely related to the quality of colonic preparation. However, data regarding colonoscopy preparations in the elderly (65 years older) are scarce.
- Trial name
- NCT02290093
- Testing
- Standard full-volume PEG, Split-dose full-volume PEG, Split-dose low-volume PEG
- Where
- 3 sites in South Korea
- Volunteers
- 230 people
- Sponsor
- Kyunghee University Medical Center
Colonoscopy, Bowel Preparation
Improving Tolerability of Bowel Preparation Laxative for Colonoscopy
The purpose of this study is to determine whether the pattern of flavoring and drinking of laxatives for colonoscopy can improve the experience of patients when they are undergoing bowel preparation for the test.
- Trial name
- NCT02062112
- Testing
- Pattern of flavoring of bowel laxative
- Where
- United States
- Volunteers
- 313 people
- Sponsor
- Howard University