Clinical trials: Polyneuropathy
Type 2 Diabetes Mellitus, Diabetic Polyneuropathy
Ultrasonographic Evaluation of Talar Cartilage Thickness in Patients With Diabetic Polyneuropathy
This study aimed to evaluate talar cartilage thickness in individuals with diabetic polyneuropathy using ultrasonography and to compare the findings with those of healthy individuals.
- Trial name
- NCT07801131
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Multiple Myeloma, Amyloidosis
A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFH
The primary aim is to establish a prospective cohort of patients with plasma cell disorders (PCDs). All of the hospitalized PCD patients who are willing to sign the informed consent form (ICF) will be included in this study.
- Conditions
- Multiple Myeloma, Amyloidosis, Cryoglobulinemia, Castleman's Disease
- Trial name
- NCT05283993
- Testing
- No intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Vasculitic Neuropathy
Polyneuropathy, Impairments and Physical Activity - The PolyImPAct Study
The project aims to investigate the validity, and reliability of outcome measures of muscle strength, functioning (gait, balance, and fine motor skills), physical activity, and patient-reported outcome measures of functioning…
- Conditions
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Vasculitic Neuropathy, POEMS Syndrome, Multifocal Motor Neuropathy
- Trial name
- PolyImPAct (NCT06040567)
- Testing
- Validity and reliability of outcome measures in polyneuropathy, Healthy controls
- Where
- Denmark
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Inflammatory Demyelinating Polyneuropathy, Charcot-Marie-Tooth Disease, Type IA
Quantification of Nerve Stiffness in Neuropathies
This project aims to understand how nerve mechanical properties are altered in patients with rare peripheral neuropathies . Stiffness of various peripheral nerves will be measured using ultrasound shear wave elastography.
- Conditions
- Chronic Inflammatory Demyelinating Polyneuropathy, Charcot-Marie-Tooth Disease, Type IA, Anti-MAG Neuropathy
- Trial name
- Nerf_SSI (NCT03397303)
- Testing
- elastography measurements
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Intensive Care Unit-acquired Weakness, Artifical Intelligence
AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness
The aim of this observational case-control study is to investigate, whether artificial intelligence can detect ultrasound-derived imaging characteristics typical for intensive care unit-acquired weakness.
- Conditions
- Intensive Care Unit-acquired Weakness, Artifical Intelligence, Ultrasound
- Trial name
- ACTIVATE (NCT06765551)
- Testing
- Neuromuscular Ultrasound
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Polyneuropathies, Diabetic Complications Neurological
Is Serum Irisin Level a Biomarker in Diabetic Polyneuropathy?
Diabetic polyneuropathy is a common complication of type 2 diabetes mellitus associated with sensory impairment and functional disability. Irisin is a myokine that has been implicated in glucose metabolism and neuroprotection.
- Conditions
- Polyneuropathies, Diabetic Complications Neurological, Diabetes Mellitus Type 2
- Trial name
- NCT07734597
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- GÜLDEN ANATACA
Diabetic Polyneuropathy, Healthy Individuals (Controls)
PULP SENSIBILITY AND MASSETER INHIBITORY REFLEX IN DIABETIC POLYNEUROPATHY
Accurate evaluation of dental pulp health is essential to avoid unnecessary endodontic treatments. In routine dental practice, pulp sensibility is commonly assessed using electric pulp testing and thermal (cold) testing.
- Trial name
- NCT07369297
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Carpal Tunnel Syndrome (CTS), Diabetic Polyneuropathy
Impact of Diabetic Polyneuropathy on Carpal Tunnel Syndrome: Shear Wave Elastography, Ultrasound, and Hand Function
This observational study examines changes in the median nerve in patients diagnosed with diabetic polyneuropathy (DPN) and carpal tunnel syndrome (CTS) using shear wave elastography, microvascular imaging, and cross-sectional…
- Conditions
- Carpal Tunnel Syndrome (CTS), Diabetic Polyneuropathy, Shear Wave Elastography, Median Nerve
- Trial name
- NCT06933511
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Diabete Mellitus, Peripheral (Sensorimotor) Diabetic Polyneuropathy
Neurophysiological, Autonomic, and Sonographic Assessment of Diabetic Peripheral Neuropathy
Diabetic peripheral neuropathy causes pain, sensory loss, and foot risk; multimodal assessment enables earlier diagnosis and improved patient management.
- Trial name
- NCT07306884
- Testing
- Nerve conduction study, Nerve ultrasound, Autonomic assessment
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Polyneuropathy, Charcot Marie Tooth Disease (CMT)
Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease)
The goal of this clinical trial is to compare the effects of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals aged 15 to 29 years, with and…
- Trial name
- PNP (NCT07152197)
- Testing
- Progressive Resistance Exercise Training
- Where
- 2 sites in Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Diabetes, Diabetic Polyneuropathy
Investigation of Ultrasonographic Measurements of Lower Extremity Nerves in Type 2 Diabetes Patients With Peripheral Polyneuropathy
The aim of this study is to quantitatively evaluate ultrasonographic measurements of the lower extremity nerves in patients diagnosed with diabetic polyneuropathy and to investigate the relationship with gait, static and dynamic…
- Trial name
- NCT06778005
- Testing
- Ultrasonography, Biodex Balance System, Douleur Neuropathique 4 (DN4) Pain Scale
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Diabetic Polyneuropathy
A Double-Blind, Placebo-Controlled Study of Fermented Deglycyrrhizinated Licorice Extract
This double-blind, placebo-controlled study evaluated the efficacy of oral α-amylase enzyme replacement therapy in treating early-stage diabetic polyneuropathy (DPN).
- Trial name
- NCT07148804
- Testing
- Fermented Deglycyrrhizinated Licorice, Non-fermented Deglycyrrhizinated Licorice
- Where
- Egypt
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Helwan University
CIDP - Chronic Inflammatory Demyelinating Polyneuropathy, Guillain-Barré Syndrome (GBS)
Multispectral Optoacoustic Imaging for the Detection of Inflammation and Damage of Peripheral Nerves in Guillain-Barré Syndrome and Chronic Inflammatory Demyelinating Polyneuropathy
The aim of this study is to assess disease activity in patients with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Guillain-Barré Syndrome (GBS) using multispectral optoacoustic tomography (MSOT).
- Trial name
- MIND (NCT07121985)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Polyneuropathies
Diagnostic Feasibility of 100 Hz Tetanic Stimulation
The goal of this observational study is to investigate the applicability of 100 Hz tetanic stimulation with an electromyography device in the exclusion of postoperative residual neuromuscular block.
- Trial name
- NCT06754995
- Where
- 2 sites in Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Debrecen
Critical Illness Myopathy, Critical Illness Polyneuropathy
Improved Recovery of Walking in Acquired Muscle Weakness
The aim of Re-Walk-Easy is to evaluate the effects of rehabilitation based on electrical stimulation on the motor performance of critically ill patients.
- Trial name
- Re-Walk-Easy (NCT06786390)
- Testing
- Rehabilitation protocol: FES, Rehabilitation protocol without FES
- Where
- Italy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Small Fiber Neuropathy, Diabetic Neuropathies
Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic Study
The aim of work is to study the clinical, electrodiagnostic and neurosonographic characteristics of diabetic patients with small fiber neuropathy in the Egyptian population, and to evaluate both the diagnostic and the prognostic…
- Conditions
- Small Fiber Neuropathy, Diabetic Neuropathies, Autonomic Neuropathy, Diabetic Peripheral Neuropathy
- Trial name
- NCT05993871
- Testing
- Clinical Evaluation/Questionnaires, Nerve Conduction Study, Small fiber electrodiagnostic tests
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tanta University
Diabetic Polyneuropathy, Diabetic Foot
The Effect of Mini Trampoline Exercise Program on Diabetic Foot Care Behavior and Polyneuropathy
This study was planned to examine the effect of home-based mini trampoline exercise program on diabetic foot care behavior and diabetic polyneuropathy in Type 2 diabetes patients.
- Conditions
- Diabetic Polyneuropathy, Diabetic Foot, Type 2 Diabetes
- Trial name
- NCT05668325
- Testing
- Mini trampoline exercise group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Peripheral Nervous System Diseases
Technique to Measure Type C Fibre Nerve Conduction Velocitynerve Fibers in Polyneuropathies
Peripheral nerve diseases can separately affect different kind of nerve fibres. Globally two kinds of fibres can be distinguished: large size and small size. The usual electromyogram only investigates large size fibres.
- Trial name
- FIBREC (NCT03870295)
- Testing
- Sympathetic skin response (SSR) measure
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer