Clinical trials: Polyp, Colonic
Familial Adenomatous Polyposis
Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis (FAP) is an autosomal dominant disorder characterized by the formation of multiple adenomatous colorectal polyps usually in the teenage years.
- Trial name
- NCT00927485
- Testing
- Calcumin (Curcumin), Risk Factor Questionnaire, Blood samples
- Where
- Puerto Rico
- Volunteers
- 44 people
- Sponsor
- University of Puerto Rico
Colorectal Cancer, Ulcerative Colitis
FishGastro Study: Fish Consumption and Gastro-Intestinal Health
The purpose of the study is to determine whether increasing the dietary intake of n-3 fatty acids by the consumption of oil-rich fish reduces the risk of developing colorectal cancer.
- Conditions
- Colorectal Cancer, Ulcerative Colitis, Polyps
- Trial name
- NCT00145015
- Testing
- Increased dietary intake of salmon or cod
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 270 people
- Sponsor
- Quadram Institute Bioscience
Adenomatous Polyposis Coli, Familial
Ursodeoxycholic Acid in the Treatment of Duodenal Adenomas in Familial Adenomatous Polyposis (FAP) Patients
Malignant transformation of adenomas of the duodenum is now the leading cause of death in familial adenomatous polyposis (FAP) patients who had a restorative proctocolectomy.
- Trial name
- NCT00134758
- Testing
- Ursodeoxycholic acid
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Colon Polyps
Prospective Study of Colon Serrated Polyps
With this study, the investigators plan to review the clinical, epidemiology, pathology, and endoscopic features of colon serrated lesions as well as outcome of endoscopic resection of these lesions.
- Trial name
- NCT02332785
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- M.D. Anderson Cancer Center
Adenoma Colon, Serrated Polyp
Cold EMR Vs Standard EMR for the Treatment of Large Nonpedunculated Homogeneous Colorectal Lesions
This study compares the effectiveness in complete resection (absence of recurrence at 6 months) the two different techniques for performing endoscopic mucosal resection (EMR) of nonpedunculated homogeneous colorectal lesions >20mm
- Conditions
- Adenoma Colon, Serrated Polyp, Serrated Adenoma, Colorectal Neoplasms
- Trial name
- NCT04418843
- Testing
- Standard Endoscopic Mucosal Resection, Cold Snare Endoscopic Mucosal Resection
- Where
- Spain
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Oscar Nogales
Colonic Polyp
Cold Snare Polypectomy Versus. Endoscopic Mucosal Resection
The investigators will investigate the efficacy of EMR compared to CSP in treatment of small colon polp (6~10mm). One aim of this study was to investigate the necessity of EMR on resection of small colon polyp.
- Trial name
- NCT02476747
- Testing
- EMR, CSP
- Where
- South Korea
- Volunteers
- 103 people
- Sponsor
- Asan Medical Center
Colorectal Cancer (CRC), Adenomatous Polyposis
Artificial Intelligence-assisted Colonoscopy in the Detection and Characterization of Colorectal Lesions
The study aims to evaluate the effectiveness of artificial intelligence-assisted colonoscopy in increasing adenoma detection rate and the accuracy in the characterization of colorectal lesions, compared to standard colonoscopy…
- Conditions
- Colorectal Cancer (CRC), Adenomatous Polyposis, Colorectal Lesions, Colorectal Cancer
- Trial name
- NCT07066046
- Testing
- Colonoscopy
- Where
- Brazil
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Colon Polyp
Prophylactic Clip Application for Colon Polypectomy in Patients With Anticoagulation
There have been very limited evidence about the bleeding complication during colon polypectomy for the patients taking warfarin.
- Trial name
- NCT02120170
- Testing
- Colon polypectomy
- Where
- South Korea
- Volunteers
- 356 people
- Sponsor
- Soonchunhyang University Hospital
Colonic Polyp
Accuracy of aCETIC Acid to Predict Histopathology of Colonic Polyps
The use of acetic acid in the characterization of polyps, produces a homogeneous white staining in sessile serrated adenomas, but not in tubular or tubulo-villous adenomas, a simple approach to predict polyp histopathology.
- Trial name
- Acetic (NCT04157803)
- Testing
- Acetic acid % spray
- Where
- Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Aleman
Colon Cancer Screening, Colon Polyps
Comparison of Colon Adenoma Detection Rate Using Two Distal Colonoscope Attachments
The goal of this study is to compare two FDA approved distal colonoscope attachment devices, in order to identify which device can increase adenoma detection rate the most without increasing procedure time or risk.
- Conditions
- Colon Cancer Screening, Colon Polyps, Colon Adenomas, Water Exchange Colonoscopy
- Trial name
- NCT02665741
- Testing
- Olympus transparent cap, Medivators Endocuff, Control
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of California, Davis
Ileal Pouch-Anal Anastomosis
Ileal Pouch-Anal Anastomosis Registry
Little is known about the factors that predispose patients to complications after an ileal pouch-anal anastomosis procedure (IPAA).
- Trial name
- IPAA (NCT01026480)
- Where
- United States
- Volunteers
- 936 people
- Sponsor
- Boston Medical Center
Colon Polyps, Colon Cancer Screening
Right Sided Colon Polyp Miss Rate: Impact Of Retroflexion In The Right Colon
Colonoscopy is the gold standard screening test for colorectal cancer. Removal of pre-malignant colon polyps during colonoscopy reduces colorectal cancer mortality by over 50%.
- Trial name
- NCT01704820
- Testing
- Retroflexion in the right colon
- Where
- 2 sites in United States
- Volunteers
- 1,020 people
- Sponsor
- Washington University School of Medicine
Colon Polyps
Difficult Colon Polypectomies
The investigators aim to define the concept of difficult colonic polypectomy and investigate whether resection methods (hot/cold snare, Endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD)), adjuvant…
- Trial name
- NCT01504425
- Where
- Romania
- Volunteers
- 91 people
- Sponsor
- Clinical Hospital Colentina
Colorectal Cancer
Prospective Randomized Comparison of Cold Snare Polypectomy and Conventional Polypectomy
The aim of this study is to compare cold snare polypectomy and conventional polypectomy for the removal and retrieval of small colorectal polyps.
- Trial name
- COLD (NCT00763425)
- Testing
- cold polypectomy, conventional polypectomy
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Showa Inan General Hospital
Adenoma Colon
White Light vs Narrow Band Imagingin the Diagnosis of Right Sided Colonic Polyps in Asymptomatic Subjects Undergoing Screening Colonoscopy
A randomized controlled crossover study to determine if narrow band imaging or white light endoscopy is superior in detecting right colonic polyps in average risk subjects undergoing screening colonoscopy
- Trial name
- WLEvsB-NBI (NCT05935124)
- Testing
- WLE first, then B-NBI
- Where
- Australia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Western Sydney Local Health District
Endoscopy, Colonoscopy
Retrospective Review of Gastrointestinal System Endoscopy Procedures
The aim of the study is retrospectively evaluating all features of endoscopic and pathological diagnoses of cases who underwent upper and lower gastrointestinal endoscopy.
- Conditions
- Endoscopy, Colonoscopy, Gastroscopy, Colonic Polyps
- Trial name
- RRGIE (NCT05012527)
- Where
- Turkey (Türkiye)
- Volunteers
- 15,448 people
- Sponsor
- Istanbul Sultanbeyli State Hospital
Colonic Polyp
Injured Submucosal Arteries After CSP for 10-19 mm Nonpedunculated Colorectal Polyps.
Cold polypectomy has the advantages of simple operation, less time-consuming and fewer complications. Guidelines have recommended cold snare polypectomy (CSP) to resect small polyps sized <9 mm.
- Trial name
- NCT05930041
- Testing
- Experimental CSP, Active Comparator HS-EMR
- Where
- Japan
- Volunteers
- 124 people
- Sponsor
- Showa Inan General Hospital
Colonic Polyp, Colon Cancer
Endoscopic Characteristics of Colonic Tumours
The purpose is to investigate whether polyps that look different at colonoscopy, have formed via different mutations and have different risks of turning into cancer.
- Trial name
- C-LST (NCT01372696)
- Testing
- Sample of polyp
- Where
- Australia
- Sponsor
- Professor Michael Bourke
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Adenomatous Polyp, Crohn Disease
Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease
This study is being done to evaluate single incision laparoscopic surgery (SILS) for colorectal diseases, compared to multi-port laparoscopic surgery.
- Conditions
- Adenomatous Polyp, Crohn Disease, Familial Adenomatous Polyposis, Hereditary Intestinal Polyposis Syndrome
- Trial name
- NCT01656746
- Testing
- therapeutic laparoscopic surgery
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ohio State University Comprehensive Cancer Center