Clinical trials: Polyp, Colonic
Colonic Polyp, Colon Adenoma
Effective Withdrawal Time and Adenoma Detection Rate
This study prospectively evaluated the role of EWT versus SWT on adenoma detection rate (ADR) and other key quality metrics. In this prospective single-center study, patients undergoing colonoscopy were enrolled.
- Conditions
- Colonic Polyp, Colon Adenoma, Artificial Intelligence
- Trial name
- NCT06063720
- Testing
- Endoscreen QC
- Where
- Hong Kong
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colorectal Polyps
Colorectal Polypectomy Upon Insertion And Withdrawal Or Upon Withdrawal Only?
The investigators aim to assess the procedure time and miss rate of polyps when performing polypectomy in the colon on the way up* and down or only on the way down.
- Trial name
- NCT01607827
- Testing
- Polyp removal upon insertion and withdrawal, Polyp removal upon withdrawal only
- Where
- Switzerland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Familial Adenomatous Polyposis
The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study
Familial adenomatous polyposis (FAP) leads to adenomas and eventual adenocarcinomas in colon and less frequently, duodenum. Chemopreventive strategies have been studied in FAP patients to delay the development of adenomas and…
- Trial name
- NCT01725490
- Testing
- Metformin
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Yonsei University
Colorectal Cancer, Polyps
MR Colonography With Fecal Tagging. Barium vs. BariumFerumoxsil
The purpose of this study is to determine whether Barium or BariumFerumoxsil is better for fecal tagging in MR colonography. Patients referred to colonoscopy are offered MR colonography before colonoscopy.
- Trial name
- NCT00332943
- Testing
- MR colonography with fecal tagging
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Herlev Hospital
Ampullary Adenoma, Familial Adenomatous Polyposis
Endoscopic Papillectomy for Ampullary Adenomas
In this single-center experience we retrospectively evaluated principal clinical outcomes of endoscopic papillectomy in all patients referred to our unit.
- Trial name
- Papillectomy (NCT03494543)
- Testing
- Endoscopic Papillectomy
- Volunteers
- 62 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Colorectal Cancer, Precancerous Condition
Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of celecoxib may keep polyps and colorectal cancer from forming in patients with familial adenomatous polyposis.
- Trial name
- NCT00685568
- Testing
- celecoxib
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- M.D. Anderson Cancer Center
Pain, Endoscopic Mucosal Resection
Prospective Evaluation of Pain Assessment and Management Protocol for Post-procedural Pain After Endoscopic Mucosal Resection of Colonic Polyps >20mm
Endoscopic mucosal resection (EMR) of large (≥20 mm) laterally spreading colonic lesions (LSL) is safe, effective and superior to surgery.
- Trial name
- NCT03471156
- Where
- Australia
- Volunteers
- 325 people
- Sponsor
- Western Sydney Local Health District
Rectal Polyp, Rectal Polyps
Rectal Tumor Resection Using the UNI-VEC Multichannel Transanal Access Device
The aim of the clinical trial is to investigate whether the use of a new multichannel endoscopic transanal access device (named UNI-VEC) is safe and effective in the resection of a rectal polyp or tumor that sits in the distal…
- Conditions
- Rectal Polyp, Rectal Polyps, Rectal Lesion, Sessile Colonic Polyp
- Trial name
- UNI-VEC (NCT06286956)
- Testing
- Treatment of rectal lesions with UNI-VEC
- Where
- 11 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Vecmedical Spain, S.L.
Colon Adenoma, Colon Polyp
Gastroenterology Artificial INtelligence System for Detecting Colorectal Polyps (The GAIN Study)
This is a prospective, multicenter, randomized controlled study to evaluate the effect of the Computer-Assisted Detection (CADe) Device on Adenomas Per Colonoscopy and Positive Percent Agreement for routine colonoscopies.
- Conditions
- Colon Adenoma, Colon Polyp, Colon Lesion
- Trial name
- GAIN (NCT05275556)
- Testing
- Computer-Assisted Detection (CADe) Device
- Where
- 7 sites in United States, Israel
- Volunteers
- 1,410 people, healthy volunteers welcome
- Sponsor
- Verily Life Sciences LLC
Polyp, Adenoma
EndoCuff-assisted Versus Standard Colonoscopy for Adenoma Detection
The EndoCuff is novel flexible cuff that can be attached to the distal tip of the colonoscope and helps to flatten large mucosal folds during withdrawal.
- Conditions
- Polyp, Adenoma, Cancer
- Trial name
- NCT02034929
- Testing
- EndoCuff-assisted colonoscopy, Standard colonoscopy
- Where
- 4 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Helios Albert-Schweitzer-Klinik Northeim
Conscious Sedation
An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Colonoscopy
Very often patients receive medication before a diagnostic procedure, like a colonoscopy, to help them relax and stay calm during the procedure. This is called procedural or minimal-to-moderate sedation.
- Trial name
- NCT00261599
- Testing
- AQUAVAN® (fospropofol disodium) Injection, Midazolam HCI
- Where
- 20 sites in United States
- Volunteers
- 300 people
- Sponsor
- Eisai Inc.
Colorectal Cancer, Colorectal Polyp
VOCs vs FIT for Colorectal Cancer Screening
Endogenous breath VOCs (Volatile Organic Compounds) are present in various excreted biological materials (urine, blood, faeces an breath) and their analysis offers a possibility for cancer screening.
- Trial name
- NCT04407416
- Testing
- Breath sampling
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Colorectal Cancer, Neoplasm of Uncertain Malignant Potential
Fludeoxyglucose F 18 PET Imaging in Determining Protein and Gene Expression Signatures in Patients With Premalignant Polyps or Colon Cancer
RATIONALE: Diagnostic imaging procedures, such as fludeoxyglucose F 18 PET, may be effective in detecting cancer or recurrence of cancer, or premalignant polyps.
- Trial name
- NCT00550628
- Testing
- DNA methylation analysis, fluorescence in situ hybridization, gene expression analysis
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Ulcerative Colitis, Crohn Disease
Systems Biology of Gastrointestinal and Related Diseases
This is a longitudinal observational study on patients with gastrointestinal and related disease. The study will be conducted for at least 10 years, following each participant over time, as they either go through relapses and…
- Conditions
- Ulcerative Colitis, Crohn Disease, Obesity, Colon Polyp
- Trial name
- NCT05579444
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Viome
Colon Polyps
Laparascopic Assisted Colonoscopic Polypectomy
Study Objective: To compare the hospital costs between the standard surgical procedure and the Laparascopic Assisted Colonoscopic Polypectomy (LACP) technique for patients with advanced polyps in the colon.
- Trial name
- NCT01986699
- Testing
- Laparoscopic Assisted Polypectomy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Stony Brook University
Colon Adenomas, Colon Polyps
Impact of Computer-aided Detection System on the Right Colon Adenoma Miss Rate
This is a prospective, multicenter randomized controlled trial designed to determine whether the use of computer-aided detection system could reduce the miss rates of adenomas, SSLs, and polyps in the proximal colon during tandem…
- Conditions
- Colon Adenomas, Colon Polyps, Sessile Serrated Lesion
- Trial name
- NCT07308743
- Testing
- Computer-aided detection-assisted colonoscopy, Conventional white-light colonoscopy
- Where
- China
- Volunteers
- 686 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Colorectal Cancer, Polyps
The Correlation of Postoperative Polyp Recurrence and Colorectal Cancer
Postoperative endoscopic polyp recurrence correlation of colorectal cancer: a retrospective cohort open-label study
- Trial name
- NCT07708415
- Testing
- Endoscopic polypectomy
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Gansu Provincial Hospital
Li Fraumeni Syndrome, Lynch Syndrome
Inherited Cancer Early Diagnosis (ICED) Study
ICED is a prospective sample collection research study, aiming to develop or validate a blood/urine biomarker which could potentially detect cancers early in individuals at high risk of developing cancers, due to certain germline…
- Conditions
- Li Fraumeni Syndrome, Lynch Syndrome, Hereditary Diffuse Gastric Cancer, Cowden Syndrome
- Trial name
- ICED (NCT06163365)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Colorectal Cancer, Polyp of Colon
Hybrid-APC Margin Ablation to Prevent Post EMR Adenoma Recurrence
Endoscopic Mucosal Resection (EMR) is the current standard for effective endoscopic resection of such colon adenomas. If resection is possible in one piece (so-called "en bloc" resection) then recurrence rates are low.
- Trial name
- h-APC_EMR (NCT04015765)
- Testing
- Hybrid Argon Plasma Coagulation and EMR procedure
- Where
- Canada
- Volunteers
- 376 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Colonic Polyps
Data Collection for CV-3E AI Software Development
The goal of this clinical trial is to collect capsule images for the development of CADe software for use with the CapsoCam® Colon (CV-3E) in healthy volunteers who have been referred for colonoscopy.
- Trial name
- NCT06916845
- Testing
- Colon Capsule
- Where
- 4 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Capso Vision, Inc.