Clinical trials: Polyp, Colonic
Colorectal Adenoma, Colorectal Polyp
Endocuff Vision Colonoscopy vs. AmplifEYE Colonoscopy
The study aims to compare the results between colonoscopies with two different attachments on the distal end of the colonoscope.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colorectal Cancer
- Trial name
- NCT03560128
- Testing
- Endocuff Vision device, AmplifEYE device
- Where
- United States
- Volunteers
- 634 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colonic Polyps, Artifical Intelligence
The Long-term Effect of Artificial Intelligence-assisted Colonoscopy on Risk of Metachronous Advanced Colonic Lesion
The goal of this prospective study is to to evaluate the prevalence of metachronous advanced colonic lesions in subsequent surveillance colonoscopies in patients who had previously undergone AI-assisted colonoscopy to…
- Conditions
- Colonic Polyps, Artifical Intelligence, Advanced Metachonous Colonic Lesion
- Trial name
- NCT07467928
- Testing
- Suveillance colonoscopy
- Where
- Hong Kong
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colorectal Polyp, Colorectal Neoplasms
Real-time AI-assisted Endocyroscopy for the Diagnosis of Colorectal Lesions
Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related death worldwide. Colonoscopy is considered the preferred method of screening for colorectal cancer, and early and…
- Trial name
- NCT06791395
- Testing
- Computer-aided diagnosis (CADx) support tool
- Where
- 3 sites in China
- Volunteers
- 570 people
- Sponsor
- The First Hospital of Jilin University
Colon Polyps, Colorectal Cancer
Study of KCC Peptide Application in the Colon
We are studying new ways to look for abnormal areas/tissues of the colon during a colonoscopy. The current scopes used for colonoscopies are very good.
- Conditions
- Colon Polyps, Colorectal Cancer, Inflammatory Bowel Disease (IBD)
- Trial name
- KCC 1B (NCT02156557)
- Testing
- Colon KCC Heptapeptide
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Danielle Kim Turgeon
Colonic Adenoma, Colonic Polyp
Evaluation of Endorings-2-assisted Colonoscopy: a New Accessory for Improvement of Adenoma Detection Rate?
Screening colonoscopy for colorectal cancer is essential to diagnose and remove adenomas, precancerous stages of colorectal cancer. Unfortunately approximately 25 % of all adenomas are missed during the examination.
- Conditions
- Colonic Adenoma, Colonic Polyp, Colonic Neoplasms, Colonoscopy
- Trial name
- Endorings-2 (NCT03385434)
- Testing
- Endorings-2
- Where
- Germany
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Colonic Polyps/Colonoscopy/Colorectal Neoplasms
Comparison of Cold and Hot Snare Resection for Colorectal Polyps Sized 10-19mm.
Patients who met the criteria for removal of 10-19mm colorectal polyps using cold snare or hot snare were included in the study, signed by endoscopic treatment written informed consent for surgery, patients with detailed tracking…
- Trial name
- NCT04451512
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Healthy Subjects
Evaluation of C-Scan in Identifying Subjects With Elevated Risk of Polyps in the Colon
The purpose of the first part of the study (subgroup R\&D) is to demonstrate the safety and performance of the C-Scan system and to collect data in order to improve the analysis process.
- Trial name
- NCT05268406
- Testing
- C-Scan System
- Where
- 10 sites in Israel
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Colon Cancer
Vitamin D and Screening Colonoscopy or Polyp Surveillance
The investigators will recruit DoD beneficiaries 18 years or older, that have been referred for a screening colonoscopy or polyp surveillance (or had one in the last 2 weeks), and have no previous diagnosis of colorectal cancer.
- Trial name
- VitDColon (NCT02269332)
- Testing
- Screening Colonoscopy
- Where
- United States
- Volunteers
- 298 people
- Sponsor
- Mike O'Callaghan Military Hospital
Artificial Intelligence (AI), Colonoscopy Education
Artificial Intelligence-assisted Colonoscopy, Tandem Study
The goal of this clinical trial is to evaluate effect of artifial intelligent (AI) system, Endoscopy as AI-powered Device (ENAD) on adenoma miss rate from colonoscopy underwent by trainee endoscopist.
- Conditions
- Artificial Intelligence (AI), Colonoscopy Education, Adenoma Colon Polyp
- Trial name
- NCT07023471
- Testing
- Group A (Trainee --> expert), Group B (Trainee +AI --> expert), Group C (Trainee --> expert + AI)
- Where
- Thailand
- Volunteers
- 364 people
- Sponsor
- Mahidol University
ColoRectal Cancer, Colonic Polyp
Retrospective Study on Epidemiology of Colorectal Lesions
Retrospective analysis on colonoscopies in the endoscopy unit of the Lyell McEwin Hospital.
- Conditions
- ColoRectal Cancer, Colonic Polyp, Colonic Neoplasms
- Trial name
- NCT03035136
- Volunteers
- 2,658 people, healthy volunteers welcome
- Sponsor
- Lyell McEwin Hospital
Colonic Neoplasms, Adenomas Serrated
Detection in Tandem Endocuff Cap Trial
A randomised back to back study comparing cap and Endocuff to detect adenomas during colonoscopy
- Conditions
- Colonic Neoplasms, Adenomas Serrated, Colo-rectal Cancer, Colon Adenoma
- Trial name
- DETECT (NCT03254498)
- Testing
- Endocuff, cap assisted colonoscopy (CAC)
- Where
- United Kingdom
- Volunteers
- 154 people
- Sponsor
- London North West Healthcare NHS Trust
Colitis,Ulcerative, Adenomatous Polyposis Coli
Registry With Information About Colitis Ulcerosa and Familial Adenomatous Polyposis Patients
The purpose of this registry is to collect information about patients in which a pouch has been created to improve in the future the quality of the surgery of the pouch.
- Conditions
- Colitis,Ulcerative, Adenomatous Polyposis Coli, Reservoir, Ileoanal
- Trial name
- KOPOF (NCT01604564)
- Where
- Belgium
- Volunteers
- 207 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ulcerative Colitis (Disorder), Familial Adenomatous Polyposis (FAP)
LATA-IBD TRIAL a Controlled Feasibility Study for the Introduction of Transanal Minimally Invasive IPAA-Surgery. Evaluation of Operative Results and Bowel Function After Introducing Transanal IPAA-surgery to Replace Conventional Laparoscopic IPAA-surgery.
This study compares the operative and functional outcomes of adding a transanal pathway to laparoscopic pelvic pouch surgery. The transanal pathway enables the surgeon to have better control when dividing the rectum and it may…
- Trial name
- LATA-IBD (NCT07278687)
- Where
- Sweden
- Volunteers
- 39 people
- Sponsor
- Sahlgrenska University Hospital
Colorectal Cancer
Celecoxib in Preventing Cancer in Patients With Rectal Polyps or Colorectal Neoplasia
RATIONALE: Celecoxib may be effective in preventing colorectal cancer in patients who have a history of rectal polyps or colorectal neoplasia.
- Trial name
- NCT00043043
- Testing
- celecoxib
- Where
- 2 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Colon Polyp
The Study of Adenoma Characteristics of the COX-2 and DNMT Expressions in the Index Colonoscopy to Predict the Polyp Recurrence During Surveillance
The colorectal cancer is the first incidence and ranks the third cancer-death cause in Taiwan. Based on the Taiwan-national colon cancer screening program, early colorectal cancer detection rate and the survival are markedly…
- Trial name
- NCT05568810
- Volunteers
- 831 people
- Sponsor
- National Cheng-Kung University Hospital
Polyp of Colon
Pronostic Score of Morbidity to Determine Risk of Complications After Endoscopic Submucosal Dissection for Colorectal Lesions
The mains complications in colo-rectal dissection are the pain, the delayed bleeding and the perforation and represent around 10%.
- Trial name
- NCT04647266
- Testing
- endoscopic submucosal dissection
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Central Hospital, Nancy, France
Colon Cancer Screening, Colon Polyps
Reduction of Conscious Sedation Requirements by Olfactory Stimulation
Colonoscopy for investigation of lower gastrointestinal complaints or for colon cancer screening is one of the more frequent procedures performed by the Divisions of General Surgery and Gastroenterology.
- Trial name
- NCT00417001
- Testing
- Aroma therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Adenomatous Polyposis Coli
A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients
The purpose of this study is to determine in a randomized, placebo-controlled, phase II trial if the combination of sulindac and erlotinib causes a significant regression of duodenal and colorectal adenomas in familial…
- Trial name
- FAPEST (NCT01187901)
- Testing
- Erlotinib, Sulindac
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Utah
Colorectal Cancer
Clinical Validation of Polydeep: an Artificial Intelligence-based Computer-aided Polyp Detection (CADe) and Characterization (CADx) System
This study is a clinical validation of Polydeep, a computer-aided polyp detection (CADe) and characterization (CADx) system. Polydeep Advance 1 is an unicentric prospective diagnostic tests trial with a paired study design.
- Trial name
- NCT05514301
- Testing
- Sensitivity of Polydeep vs high experienced endoscopists for colorectal polyp detection
- Where
- Spain
- Volunteers
- 205 people
- Sponsor
- Fundacin Biomedica Galicia Sur