Clinical trials: Polyp, Colonic
Colorectal Cancer
A Multi Center Study Comparing the Efficacy of CAD EYE and the Standard of Care (White Light )
This study is to assess the sensitivity and added benefits of CADEYE compared to standard care (white-light) in detecting colon polyps in patients undergoing colonoscopy.
- Trial name
- NCT05523271
- Testing
- CAD EYE (Computer Aided Diagnosis ----?
- Where
- Egypt
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Familial Adenomatous Polyposis
A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis
The purpose of this study is to determine the efficacy and safety of a personalized surveillance and intervention protocol for duodenal and gastric polyposis in patients with familial adenomatous polyposis (FAP)
- Trial name
- NCT04677998
- Testing
- Personalized surveillance and intervention protocol
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Colonoscopy, Polyp of Colon
Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used
This is a study to compare two different, but normally, used methods of colonoscopy in patients that require a routine or repeat colonoscopy.
- Trial name
- ASGE (NCT03566615)
- Testing
- CAP-straight, CAP-daisy, water
- Where
- 7 sites in United States, China and 2 more
- Volunteers
- 1,630 people, healthy volunteers welcome
- Sponsor
- VA Greater Los Angeles Healthcare System
Cancer Colon, Polyp of Colon
Clinical Trial Verifying C-REX LapAid and C-REX DMH/DMHC
In colorectal surgery, hand suturing and stapling are routine methods for performing intestinal anastomoses, and these methods appear to be similar in terms of clinical safety.
- Trial name
- NCT03179358
- Testing
- C-REX Ring-locking Procedure
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Carponovum AB
Ampullary Adenoma, Familial Adenomatous Polyposis
Endoscopic Papillectomy for Ampullary Adenomas
In this single-center experience we retrospectively evaluated principal clinical outcomes of endoscopic papillectomy in all patients referred to our unit.
- Trial name
- Papillectomy (NCT03494543)
- Testing
- Endoscopic Papillectomy
- Volunteers
- 62 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Colorectal Cancer
Polyp Measurement Device
Colorectal cancer is the second-leading cause of cancer death in the United States. Colorectal cancer screening is recommended to begin at age 50 years for most men and women at average risk for this disease.
- Trial name
- NCT03856255
- Testing
- Micro-Tech Endoscopic Gauge
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colorectal Cancer, Esophageal Cancer
Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients
RATIONALE: Studying samples of tissue, blood, urine, stool, and other biological fluids from patients with cancer and from healthy volunteers undergoing colonoscopy or endoscopy may help doctors identify and learn more about…
- Conditions
- Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT00899626
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Vanderbilt University Medical Center
Familial Adenomatous Polyposis
Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis
The purpose of this study is to collect prospective observational data regarding patients with diagnosed Familial Adenomatous Polyposis (FAP) undergoing cold snare polypectomy for duodenal adenomas
- Trial name
- COPDA (NCT03471403)
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Western Sydney Local Health District
Serrated Polyp, Colorectal Neoplasms
Increasing Serrated Polyp Detection With a Brief Awareness Training
In this non-randomized controlled trial, a semi-random group of Dutch endoscopist receive an oral training about the significance of serrated polyps.
- Trial name
- NCT03902899
- Testing
- Educational intervention (oral presentation)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Tubular Adenoma, Colon Cancer
Prospective Randomized Controlled Trial Comparing Water and Air Colonoscopy in a Community Based Setting
The purpose of this study is to determine if screening colonoscopy performed on adults with the water exchange method, as opposed to the air method, will have a higher adenoma detection rate.
- Conditions
- Tubular Adenoma, Colon Cancer, Hyperplastic Polyp
- Trial name
- NCT01729416
- Testing
- Water Exchange Colonoscopy, Air Colonoscopy
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of California, Davis
Colorectal Cancer, Colonic Polyp
Effect of Low-volume (1L) vs Intermediate-volume (2L) Bowel Preparation on Cost-effectiveness and Quality of Life
Adequate bowel preparation for colonoscopy is paramount for optimal diagnostic accuracy and safety. However, the need for high volumes to clean the colon often makes it difficult for patients to adhere to.
- Trial name
- RESULT (NCT05242562)
- Testing
- Plenvu, Moviprep
- Where
- Netherlands
- Volunteers
- 509 people
- Sponsor
- Radboud University Medical Center
Colorectal Cancer
Aspirin and/or Folic Acid in Preventing Recurrent Colorectal Polyps
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of aspirin and/or folic acid may be effective in preventing recurrent polyps in patients who have…
- Trial name
- NCT00033319
- Testing
- folic acid, acetylsalicylic acid
- Where
- 32 sites in United Kingdom
- Sponsor
- Queen's Medical Center
Colonic Polyp
Blue Light Imaging (BLI) for Optical Diagnosis of Colorectal Polyps
Several imaging technologies have been developed in order to enable the endoscopists to differentiate neoplastic from non-neoplastic lesions.
- Trial name
- BIRD (NCT03746171)
- Testing
- Colonic polyp characterization by BLI
- Where
- Italy
- Volunteers
- 324 people
- Sponsor
- Valduce Hospital
Colorectal Neoplasms, Colonic Polyps
Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study
This prospective randomized controlled study aims to evaluate the diagnostic accuracy of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for detection and optical characterization of…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma, Serrated Polyps
- Trial name
- INSIGHT (NCT07797361)
- Testing
- White Light Endoscopy, Versatile Intelligent Staining Technology, Spectral Flexible Imaging
- Where
- Brazil
- Volunteers
- 990 people
- Sponsor
- Alexandre Vontobel Padoin
Colon Adenoma, Colonoscopy
Adenoma Detection Rate in Water and Air Colonoscopy Using Computer-aided System
Water exchange (WE) is an effective insertion method to minimize insertion discomfort and maximize ADR. It is characterized by infusing water to guide insertion in an airless lumen with suctioning of infused water during…
- Trial name
- NCT05448300
- Testing
- Colonoscopy with water exchange or air insufflation methods
- Where
- 2 sites in United States, Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Colonic Polyps
Australian Multicentre Colonic Endoscopic Mucosal Resection Study
A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis.
- Trial name
- ACEEMR (NCT01368289)
- Testing
- Endoscopic Mucosal Resection
- Where
- Australia
- Volunteers
- 3,072 people
- Sponsor
- Professor Michael Bourke
Colon Polyp
Collecting Recorded Videos of Colonoscopy Screening Tests
The study shall mainly help to better evaluate the performance the APDS device and secondly it may help to assess the potential of the future alpha version of the device to be a useful and effective for the detection of colon…
- Trial name
- NCT03891290
- Testing
- Collecting recorded videos of Colonoscopy screening tests of the general population
- Where
- Israel
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD
Colon Cancer
Polyp Detection With the EndoRings™: A Randomized Tandem Colonoscopy Study
To compare the adenoma miss rate with the EndoRings™ vs. the adenoma miss rate with Standard view colonoscopy. To compare the polyp miss rate with the EndoRings™ vs.
- Trial name
- NCT01955122
- Testing
- Tandem Colonoscopy
- Where
- 3 sites in United States, Israel and 1 more
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- EndoAid
Liver Cirrhosis, Polyps of Colon
Effect of HFNC on Incidence of Hypoxia During Sedated Gastrointestinal Endoscopy in Critical Patients
High flow nasal cannula oxygenation (HFNC) offers high flow and concentration oxygen delivery, providing excellent non-respiratory oxygenation. As a relatively new oxygen delivery method, it has gained widespread use.
- Conditions
- Liver Cirrhosis, Polyps of Colon, Gastrointestinal Dysfunction
- Trial name
- NCT07252102
- Testing
- High-flow nasal catheter oxygen, regular nasal catheter oxygen
- Where
- 3 sites in China
- Volunteers
- 450 people
- Sponsor
- Zhejiang University
Wound Endoscopical, Colon, After Polyp Resection, Colon
Efficacy of EndoClot™ Spraying After Endoscopic Resection of Large Colorectal Polyps
The effectiveness of colonoscopy in reducing colorectal cancer mortality relies on the detection and removal of neoplastic polyps.
- Trial name
- EndoClot™ (NCT05029934)
- Testing
- use of EndoClot
- Where
- 5 sites in Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf