Clinical trials: Polyp Colorectal
Post-endoscopic Mucosal Resection of Colon Polyps
Assessing a Endoscopic Mucosal Resection Site Using Different Endoscopic Imaging Methods
The purpose of this study is to compare the accuracy of using different endoscopic imaging technique (white light, white light with near focus, narrow band imaging (NBI), NBI with near focus) for detection of residual neoplastic…
- Trial name
- NCT02668198
- Testing
- Olympus CF190 Colonoscope High definition white light, Olympus CF190 Colonoscope White light with near focus, Olympus CF190 Colonoscope Narrow band imaging
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Michael Wallace
Adenomatous Polyps
Non-invasive Risk Stratification of CR AMN/SSP
The purpose of this study is to determine the clinical utility of stool and blood methylation tests for detection of advanced mucosal neoplasia (AMN) and sessile serrated polyps (SSP).
- Trial name
- FIT (NCT02476682)
- Testing
- blood or stool samples will be collected
- Where
- Australia
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Professor Michael Bourke
Colonic Polyp
Effect of Epinephrine on Post-polypectomy Pain
Epinephrine is widely used in endoscopic mucosal resection of large polyps to prevent post-polypectomy bleeding. No previous studies looked at increase in immediate post-polypectomy pain with the use of epinephrine.
- Trial name
- NCT04065451
- Testing
- Epinephrine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Indiana University
Polyp of Large Intestine
Cold Snare Polypectomy Vs. Cold Forceps Polypectomy Using Narrow-band Imaging Endoscopy for Removal of Diminutive Colorectal Polyps
The purpose of this study is to compare cold snare polypectomy and cold forceps polypectomy using narrow-band imaging endoscopy for removal of diminutive colorectal polyps.
- Trial name
- NCT02201147
- Testing
- Cold biopsy polypectomy, Cold snare polypectomy
- Where
- South Korea
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Colon Polyps
Real-time Diagnosis of Colorectal Polyps Using Narrow-Band Imaging
Accurate optical diagnosis of colorectal polyps could allow a "resect and discard" strategy with surveillance intervals determined based on the results of the optical biopsy.
- Trial name
- NCT02516748
- Testing
- Feedback
- Where
- South Korea
- Volunteers
- 3,268 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colorectal Polyp, Colorectal Cancer
Detection of Endoscopic Resection Scars and Delineation of Recurrence is Trainable
Colorectal cancer is prevented by colonoscopy and polypectomy. Failure to recognize the endoscopic resection scar after Endoscopic Mucosal Resection (EMR) risks unrecognized recurrent or residual adenoma (RRA), which may…
- Trial name
- SCAR (NCT06193356)
- Testing
- Learning tool
- Where
- Belgium
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
MutYH-associated Polyposis
MUTYH-associated Polyposis
This is single-center, prospective, non-randomized study
- Trial name
- MAP (NCT03847532)
- Testing
- Sanger sequencing method
- Where
- Russia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Colorectal Neoplasms, Colorectal Polyp
MS Versus NICE for Colorectal Lesions
OBJECTIVE: Our study aimed to compare a recently-developed endoscopic classification with an established one for colorectal lesions in a randomised trial between 2013 and 2015.
- Trial name
- NCT02963207
- Testing
- Modified Sano's classification, NICE classification
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Lyell McEwin Hospital
Colonic Polyp, Colon Cancer
Improving Outpatient Colonoscopy Bowel Prep With the Orton Score
Colonoscopy is a common endoscopic procedure which the UVA Gastroenterology \& Hepatology department performs on a daily basis for both screening/surveillance and diagnostic/therapeutic intent.
- Trial name
- NCT04093557
- Testing
- Orton Score, Typical Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Colorectal Cancer, Colorectal Polyp
Epigenetic Regulation of Colorectal Polyps and Cancer
The goal of this study is to learn about the epigenetic and genetic regulation (microRNA/mRNA) of colorectal polyps and their evolvement as polyps and to colorectal cancer.
- Conditions
- Colorectal Cancer, Colorectal Polyp, Colorectal Adenoma, Colorectal Neoplasms
- Trial name
- NCT06206603
- Testing
- Intestinal biopsies, Blood sample
- Where
- Sweden
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Region Skane
10-20mm Colorectal Polyp
Optimal Resection Technique for Medium-sized (10-20mm) Colorectal Polyps
This study will investigate which resection technique (Endoscopic Mucosal Resection (EMR), cold EMR, or underwater EMR) leads to lower recurrence rates and less adverse events in patients with colorectal polyps (10-20mm).
- Trial name
- NCT05849623
- Testing
- Endoscopic Mucosal Resection (EMR), Cold Endoscopic Mucosal Resection (C-EMR), Underwater Endoscopic Mucosal Resection (U-EMR)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Colorectal Polyps
Comparison of Two Types of Biopsy Forceps for Obtaining Cold Biopsy Polypectomy for Small Sessile Colorectal Polyps Less Than 6 mm in Diameter
The purpose of this study is to evaluate the efficacy of the new RJ4 compare with the standard RJ3 biopsy forceps for performing polypectomy for small colorectal polyps.
- Trial name
- NCT00855790
- Testing
- evaluate the effectiveness of the RJ4 biopsy forcep versus the RJ3 biopsy forcep
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Florida
Colonic Polyps, CRC (Colorectal Cancer)
A Prospective Study to Evaluate the Performance of a Real-time System in the Estimation of Colorectal Polyp Size
Colorectal polyp size is related to the risk of exhibiting advanced histological features. Moreover, polyps larger than 10 mm are associated with an elevated risk of metachronous advanced neoplasia and colorectal cancer (CRC).
- Conditions
- Colonic Polyps, CRC (Colorectal Cancer), Artificial Intelligence (AI)
- Trial name
- EndoAIM (NCT06957015)
- Testing
- EndoAIM
- Where
- Hong Kong
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colonic Polyps, Esophageal Diseases
Confocal Probe-based Endoscopic Imaging, Colorectal Cancer, Gastrointestinal (GI) Pathologies
The recently developed endoscopic Confocal probe microscopy system allows imaging of surface epithelium during ongoing endoscopy (upper and lower) with the potential of immediate diagnosis of various GI pre-malignant and…
- Trial name
- ASGE-FNDT-1 (NCT00874263)
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colon Cancer, IBS
Patient Satisfaction With Propofol for Out Patient Colonoscopy
The primary purpose of this study is to determine if patient satisfaction with propofol is better than with non-propofol anesthesia for outpatient colonoscopies.
- Conditions
- Colon Cancer, IBS, Polyps
- Trial name
- NCT02937506
- Testing
- Propofol, Fentanyl Plus Midazolam
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mount Carmel Health System
Colon Cancer, Colon Diseases
PeerScope B System™ Clinical Protocol
The PeerScope B System™ by PeerMedical Ltd. is intended to provide visualization (via a video monitor) and therapeutic access to the lower intestinal tract.
- Conditions
- Colon Cancer, Colon Diseases, Colon Polyps, Colon Adenomas
- Trial name
- NCT01483040
- Testing
- colonoscopy system (PeerScope B System™)
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- PeerMedical Ltd.
Polyps, Cardiovascular Diseases
Lifestyle and Dietary Pattern in Relation to Precursor Lesions of Colorectal Cancer and Cardiometabolic Diseases
The association between lifestyle and dietary patterns with precursor lesions of colorectal cancer and cardiometabolic diseases is still unclear.
- Trial name
- NCT03708952
- Where
- 2 sites in China
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Sessile Serrated Adenoma, Colorectal Polyp
Assessing the Agreement Between Endoscopic and Histopathological Diagnosis of Colorectal Sessile Serrated Lesions.
The goal of this observational study was to assess the degree of agreement between the endoscopic and anatomopathological diagnosis of sessile serrated colorectal lesions in adult patients undergoing colonoscopy in Hospital…
- Conditions
- Sessile Serrated Adenoma, Colorectal Polyp, Adenoma Colon, Colorectal Cancer
- Trial name
- NCT06173297
- Where
- Brazil
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Probe-based Confocal Laser Endomicroscopy, Artificial Intelligence
Automatic Classification of Colorectal Polyps Using Probe-based Endomicroscopy With Artificial Intelligence
Probe-based confocal laser endomicroscopy (pCLE) is an endoscopic technique that enables real-time histological evaluation of gastrointestinal mucosa during ongoing endoscopy examination.
- Conditions
- Probe-based Confocal Laser Endomicroscopy, Artificial Intelligence, Colorectal Polyps
- Trial name
- NCT03787784
- Testing
- AI presentation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shandong University
Colorectal Polyp
Optical Diagnosis Versus Laser Measurement of Polyps' Size During Colonoscopy and Implications for Surveillance
Recent updates of the guidelines on polyp surveillance of the American Society of Gastrointestinal Endoscopy (ASGE) and European Society of Gastrointestinal Endoscopy (ESGE) increasingly focus on size of polyps as an important…
- Trial name
- NCT05489380
- Testing
- AccuMeasure
- Where
- 3 sites in United States, Netherlands
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center