Clinical trials: Polyps
Colorectal Neoplasms, Gastrointestinal Microbiome
Predicting Adenomatous Polyps in the Colon Using Images of a Human Tongue
This is a prospective, multicenter, single-arm clinical investigation designed to evaluate the accuracy of the Gixam™ System in identifying subjects with colorectal adenomas compared to optical colonoscopy.
- Trial name
- NCT06305364
- Testing
- Gixam
- Where
- 3 sites in United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Jubaan Ltd.
Nasal Polyps
Mint Tea for the Treatment of Nasal Polyps
The purpose of this study is to evaluate the safety and efficacy of a new treatment for nasal polyps as compared to placebo (an inactive substance). The treatment involved is mint tea high in rosmarinic acid.
- Trial name
- NCT00465543
- Testing
- Mint tea high in rosmarinic acid, Mint tea low in rosmarinic acid
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Colon Cancer
Screening and Risk Factors of Colon Neoplasia
The investigators propose a screening population-based study to systematically evaluate the accuracy and clinical relevance of sDNA testing as a potential alternative to colonoscopy screening.
- Trial name
- NCT01647776
- Testing
- Stool DNA Test, biopsies of rectal and colon mucosa, Questionnaires
- Where
- United States
- Volunteers
- 3,315 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Colo-rectal Cancer, Cancer Colon
AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test
Freenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early.
- Conditions
- Colo-rectal Cancer, Cancer Colon, Cancer, Rectum, Neoplasms,Colorectal
- Trial name
- NCT03688906
- Where
- 30 sites in United States, Canada
- Volunteers
- 3,275 people, healthy volunteers welcome
- Sponsor
- Freenome Holdings Inc.
Barrett Esophagus, Polyps
A Prospective Study Comparing the Accuracy of Olympus Lucera Spectrum Technology vs Olympus Lucera Elite Technology in the in Vivo Diagnosis of Barrett's Oesophagus and Colorectal Polyps: The ELITE Study
Barrett's oesophagus is a condition where the lining of the oesophagus (gullet) wall changes. People with Barrett's oesophagus are at risk of developing oesophageal cancer but can have regular checkups to detect changes before…
- Trial name
- ELITE (NCT03073226)
- Testing
- Olympus Elite, Olympus Spectrum
- Where
- United Kingdom
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Adenoma Colon
Efficacy of Artificial Intelligence-assisted Colonic Polyp Detection System
This is a randomized controlled multicenter clinical trial of computer-aided detection (CADe) system for the adjuvant diagnosis of intestinal polyps/adenomas ever conducted in a Chinese population.
- Trial name
- NCT05941689
- Testing
- AI-assisted colonoscopy
- Where
- 2 sites in China
- Volunteers
- 1,906 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Endometrial Polyp, Endometrial Diseases
The Use of Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation
The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety…
- Trial name
- NCT06316206
- Testing
- Ethinylestradiol/Dienogest 0.03mg/2mg
- Where
- 2 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Colorectal Polyp
Validation of the NICE Classification Using Pentax Chromoendoscopy
Colorectal cancer (CRC) is the most frequent gastrointestinal tumor and the second cause of cancer related death. Colonoscopy is currently the recommended method for detection of polyps and cancers in the colon.
- Trial name
- NCT03155308
- Testing
- Pentax chromoendoscopy (i-scan and Optical Enhancement)
- Where
- Ecuador
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
COVID-19, Temporomandibular Disorder
Temporomandibular Joint and COVID-19
There is evidence that CV-19 is associated with joint symptoms, but there are no specific data on the temporomandibular joint (TMJ). It is also known that the systemic health status can impact the immune system.
- Conditions
- COVID-19, Temporomandibular Disorder, ASA Triad
- Trial name
- NCT05077189
- Testing
- Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) scale
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Colorectal Cancer, Colorectal Neoplasms
Early Detection of Advanced Adenomas and Colorectal Cancer
This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenocarcinoma
- Trial name
- AACRC (NCT06342440)
- Testing
- DENEB
- Where
- 6 sites in United States, China and 3 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Benign Polyps of Large Intestine
Resect and Discard Approach to Diminutive Colonic Polyps
Resect and discard (RD) is a new paradigm for management of diminutive colorectal polyps wherein histology is determined by real-time endoscopic imaging; polyps are then resected and discarded rather than sent for…
- Trial name
- RD (NCT01877525)
- Testing
- Colonoscopy
- Where
- United States
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Colorectal Cancer, Colorectal Neoplasms
Clinical Performance of the Mainz Biomed Colorectal Cancer Screening Test for Colorectal Cancer and Advanced Adenoma
This study is to determine how the Mainz Biomed Colorectal Cancer Screening Test works when used in people aged ≥45 years of age and at an average risk of developing colorectal cancer.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenoma
- Trial name
- reconAAsense (NCT05636085)
- Testing
- Mainz Biomed Colorectal Cancer Screening Test
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Mainz Biomed
Adenoma Colon Polyp, Sessile Serrated Adenoma
The Impact of a Colonoscopy Monitoring Program on Endoscopists' Performance
The goal of this clinical trial is to learn if colonoscopy monitoring program works to adenoma detection rate in endoscopists. It will also learn about the impact on sessile serrated lesion detection rate, adenomas per…
- Trial name
- NCT06577610
- Testing
- Feedback from colonoscopy monitoring program
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colorectal Cancer, Polyps
Aspirin/Folate Prevention of Large Bowel Polyps
This is a randomized controlled trial of aspirin and/or folate supplementation for the prevention of the recurrence of neoplastic polyps (adenomas) of the large bowel.
- Conditions
- Colorectal Cancer, Polyps, Adenomas
- Trial name
- NCT00272324
- Testing
- Aspirin, Folate
- Where
- 9 sites in United States, Canada
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Colonic Polyp, Colorectal Cancer
Study on Second Forward View Examination in the Right Colon
It is estimated that there are about 1.4 million patients with colorectal cancer (CRC) worldwide, with a rising trend in CRC incidence in many Asian Pacific countries.
- Trial name
- NCT03121495
- Testing
- Second forward view (SFV) examination of the right colon
- Where
- 3 sites in Hong Kong
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Polyp of Colon
Clinical vAliDation of ARTificial Intelligence in POlyp Detection
This study is an open label, unblinded, non-randomized interventional study, comparing the investigational artificial intelligence tool with the current "gold standard": Data acquisition will be obtained during one scheduled…
- Trial name
- CAD-ARTIPOD (NCT04442607)
- Testing
- artificial intelligence image processing
- Where
- Belgium
- Volunteers
- 856 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colorectal Polyp
Comparative Study of Anchoring-tip vs. Conventional EMR of Colorectal Polyps
Endoscopic mucosal resection (EMR) is an effective and has been widely used technique for the treatment of superficial colorectal neoplasms.
- Trial name
- NCT04825457
- Testing
- Anchoring-tip vs. Conventional
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Chilgok Hospital
Surveillance Endoscopy for Colorectal Cancer, Artificial Intelligence
Surveillance Modified by Artificial Intelligence in Endoscopy (SMARTIE)
Evaluation of an artificial intelligence system for polyp detection (CADe)
- Conditions
- Surveillance Endoscopy for Colorectal Cancer, Artificial Intelligence, Polyps of Colon, CADe
- Trial name
- SMARTIE (NCT05006092)
- Testing
- ENDOMIND
- Where
- Germany
- Volunteers
- 1,149 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Nasal Polyps, Chronic Sinusitis
Wound Healing After Endoscopic Sinus Surgery
This study aims to determine the effect of Thymoquinone (0.5%) and olive oil ointment on Wound healing after Endoscopic sinus surgery.
- Trial name
- NCT06070311
- Testing
- Thymoquinone (0.5%) and Olive oil ointment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University