Clinical trials: Polyps Uterus
Endometrial Polyp, Endometrial Diseases
The Use of Nomegestrol Acetate/Estradiol in Random Start Rapid Endometrial Preparation
The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety…
- Trial name
- NCT06316219
- Testing
- Nomegestrol Acetate/Estradiol 2.5mg/1.5mg
- Where
- 2 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Endometrial Polyp
Endometrial Polyps Regression With Progesterone Therapy
This prospective randomized study will compare the regression rates of women managed with watch-and-wait approach and of those treated with 3 cycles of luteal 25mg subcutaneous progesterone from 18 to 25 days of menstrual cycle
- Trial name
- NCT03309709
- Testing
- subcutaneous progesterone
- Where
- 2 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Asherman Syndrome, Endometrial Polyp
Efficiency of INTERCOAT (Oxiplex/AP Gel) in Preventing Intrauterine Adhesion Formation in Hysteroscopic Surgery
The study purpose is to examine the influence of INTERCOAT in prevention of intra-uterine adhesions formation after any hysteroscopic surgery.
- Conditions
- Asherman Syndrome, Endometrial Polyp, Uterine Myoma
- Trial name
- NCT01637974
- Testing
- INTERCOAT administration
- Where
- Israel
- Volunteers
- 130 people
- Sponsor
- Carmel Medical Center
Uterine Fibroids, Polyps
Comparative Sedation Study of the MyoSure Hysteroscopic Tissue Removal System
The purpose of this study is to develop a recommended local anesthetic protocol and post-treatment pain management regimen, in order to assure patient comfort during office-based treatment with the MyoSure Hysteroscopic Tissue…
- Trial name
- NCT00979342
- Testing
- Hysteroscopic Morcellator
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Hologic, Inc.
Endometrial Polyp
Hand Driven Versus Motor Driven Hysteroscopic Tissue Removal System for Polypectomy: Long-term Results
In this study, a comparison is made between two types of polyp resection methods (hand driven and motor driven morcellation). More specifically, the effects of the resection on symptoms such as abnormal uterine bleeding, and on…
- Trial name
- NCT05337605
- Where
- Netherlands
- Volunteers
- 87 people
- Sponsor
- University Hospital, Ghent
Uterine Polyps, Uterine Fibroids
Office Hysteroscopy Versus Operating-room Hysteroscopy for Uterine Lesions
HYPHOP is a multicenter, randomized clinical trial comparing two care pathways for women who need operative hysteroscopy to treat intrauterine lesions, such as uterine polyps, small submucosal fibroids, or retained pregnancy…
- Conditions
- Uterine Polyps, Uterine Fibroids, Retained Products of Conception
- Trial name
- HYPHOP (NCT07908615)
- Testing
- Operating-room hysteroscopy with resectoscope, Outpatient hysteroscopic morcellation/aspiration
- Where
- 9 sites in France
- Volunteers
- 474 people
- Sponsor
- Nantes University Hospital
Myoma;Uterus, Polyp Endometrium
Remimazolam and Remifentanil Without Neuromuscular Blocking Agent
Remimazolam is a novel drug approved for induction and maintenance of general anesthesia. This study aims to check the appropriate dose and patient response by administering remimazolam and remifentanil in surgery that does not…
- Conditions
- Myoma;Uterus, Polyp Endometrium, Unspecified Condition Associated With Female Genital Organs and Menstrual Cycle
- Trial name
- NCT05025410
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Bundang Hospital
Pancreatic Cancer, Thyroid Cancer
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer…
- Conditions
- Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- iCaRe2 (NCT02012699)
- Where
- 42 sites in United States
- Volunteers
- 999,999 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Endometrial Polyp, Oxidative Stress
Thiol Disulfide Balance and Oxidative Stress Change in Endometrial Polyp Patients
Changes in Thiol Disulfide Balance and Oxidative Stress Mechanisms in Patients with Endometrial Polyps
- Trial name
- NCT06826495
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Mardin Artuklu University
Hysteroscopy, Minimally Invasive Surgical Procedures
Implementation of Hysteroscopy in Flanders and the Netherlands
By means of a questionnaire the investigators will study the implementation of hysteroscopy in Flanders and the Netherlands
- Conditions
- Hysteroscopy, Minimally Invasive Surgical Procedures, Polyp, Myoma
- Trial name
- NCT02853695
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- University Ghent
Endometrial Polyp
Dydrogesterone in the Treatment of Endometrial Polyps
This study is intended to observe the therapeutic effect of dydrogesterone on endometrial polyps and provide a reference for clinical treatment.
- Trial name
- NCT03790215
- Testing
- Dydrogesterone
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Endometrial Cancer, Endometrial Neoplasms
Pilot Study: Can Ultrasound Guided Biopsy be Used as an Alternative to Hysteroscopy?
Aim: Assess accuracy of histological diagnosis using ultrasound guided biopsy for women with suspected endometrial cancer (as an alternative to hysteroscopy guided biopsy).
- Conditions
- Endometrial Cancer, Endometrial Neoplasms, Endometrial Hyperplasia, Endometrial Polyp
- Trial name
- NCT03207126
- Testing
- Ultrasound guided biopsy
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Imperial College London
Endometrial Polyps
Morcellator Versus Resectoscope in the Treatment of Uterine Polyps by Hysteroscopy
Intrauterine pathologies are currently treated by hysteroscopic resection. In this surgical procedure, the intrauterine pathology is resected by a transcervical approach in several fragments using a mono or bipolar cove after…
- Trial name
- RESMO (NCT02472197)
- Testing
- Hysteroscopic morcellation, Standard hysteroscopic resection
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Strasbourg, France
Endometrial Polyp Benign, Retained Products of Conception
The Use of a Morcellator in Operative Hysteroscopy for Benign Intracavitary Lesions: a Feasibility Study
Polyps, intracavitary myomas and retained products of conception (RPOC) are common benign intracavitary lesions of the uterus and frequently cause abnormal uterine bleeding or pain.
- Conditions
- Endometrial Polyp Benign, Retained Products of Conception, Myoma;Uterus
- Trial name
- NCT05811286
- Testing
- Hysteroscopic morcellation 19 Fr. intrauterine BIGATTI Shaver for uterine intracavitary lesions
- Where
- 2 sites in Belgium
- Volunteers
- 56 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Large Intrauterine Polyps, Smaller Type 0 and 1 Myomas
The Hysteroscopic Morcellator (HM).
Rationale: The hysteroscopic morcellator (HM) is a novel technique for removal of intrauterine polyps, myomas and placental tissue. It withholds some technical advantages over resectoscopy.
- Conditions
- Large Intrauterine Polyps, Smaller Type 0 and 1 Myomas, Residual Placental Tissue
- Trial name
- HM (NCT01537822)
- Testing
- Hysteroscopic morcellator, Resectoscope
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 253 people
- Sponsor
- University Hospital, Ghent
Intrauterine Diseases, Myomas
A New Alternative to Traditional Hysteroscopy
Hysteroscopy is a procedure designed for the diagnosis and the treatment of intra-uterine diseases. The development of smaller hysteroscopes allowed to change the approach to the intra-uterine lesions unifying the diagnostic and…
- Conditions
- Intrauterine Diseases, Myomas, Polyps
- Trial name
- NCT01430208
- Testing
- resectoscopy
- Where
- Italy
- Volunteers
- 401 people
- Sponsor
- Catholic University of the Sacred Heart
Endometrial Polyps
A Trial Comparing Morcellation With Electrical Resection for Removal of Uterine Polyps
Outpatient polyp treatment can be performed in a few different ways but generally involves passing a special type of hysteroscope (3-6 millimetre in diameter) into the womb through which specifically designed miniature operating…
- Trial name
- MERT (NCT01509313)
- Testing
- hysteroscopic morcellator (TruClear), Bipolar Electrical resectoscope (Versapoint)
- Where
- United Kingdom
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Abnormal Uterine Bleeding, Postmenopausal Bleeding
Use of Nitrous Oxide During Office Hysteroscopy
The goal of this clinical trial is to assess the use of inhaled nitrous oxide during office hysteroscopy. The main questions it aims to answer are: Does it reduce pain during the procedure? Does it increase the success rate? Does…
- Conditions
- Abnormal Uterine Bleeding, Postmenopausal Bleeding, Endometrial Polyps, Retained Products of Conception
- Trial name
- NCT07074795
- Testing
- Inhalation of Nitrous Oxide (N₂O) during Office Operative Hysteroscopy, inhalation of ambient air during office hysteroscopy
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Maaynei Hayesha Medical Center
Infertility
Expression of HOXA10 and HOXA11 in the Endometrium of Infertility Patients With an Endometrial Polyp Before and After Polypectomy
The aim of this study is to measure the expression of HOXA10 and HOXA11 in the endometrium of infertility patients with an endometrial polyp before and after polypectomy.
- Trial name
- NCT02761278
- Testing
- Endometrial biopsy
- Volunteers
- 20 people
- Sponsor
- Hillel Yaffe Medical Center
Uterine Fibroids, Polyps
MyoSure Hysteroscopic Tissue Removal System Registry Study
The objective of this study is to demonstrate the safety and effectiveness of community gynecologist initiated treatment of intra-uterine polyps and submucosal fibroids with the MyoSure Hysteroscopic Tissue Removal System in a…
- Trial name
- NCT01369758
- Testing
- MyoSure Tissue Removal System
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Hologic, Inc.