Clinical trials: Polytrauma Patients
Trauma, Multiple
Early Norepinephrine in Trauma Patients With Hemorrhagic Shock
The goal of this clinical trial is to learn if norepinephrine works to treat trauma patients with hemorrhagic shock. It will also learn about the safety of norepinephrine.
- Trial name
- ENTHeS (NCT06977659)
- Testing
- Norepinephrine
- Where
- 2 sites in Thailand
- Volunteers
- 40 people
- Sponsor
- Visarat Palitnonkiat
Trauma, Hemorrhage
Incidence of Trauma Induced Coagulopathy in Patients With Prehospital Administration of Fibrinogen
The purpose of the study is to find out the incidence of trauma induced coagulopathy in patients with severe trauma who received fibrinogen prior admission to emergency department during prehospital care.
- Conditions
- Trauma, Hemorrhage, Coagulopathy
- Trial name
- TICAF (NCT03572309)
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- Masaryk University
Clavicle Fracture, Chest Injury
Operative Versus Non-Operative Treatment of Clavicle Fracture in PolyTrauma
About 90% of chest injuries in America are due to blunt forces, mostly as a result of motor vehicle collisions and falls. Severity varies from minor bruising to severe chest injuries.
- Trial name
- NCT01133769
- Where
- United States
- Sponsor
- Anna Rockich
Trauma, Multiple, Gun Shot Wound
A Snapshot Study of Patients Affected by Gunshot Related Injuries in Trauma in South Africa
Introduction- Gun violence represents an important cause of disability to the working age population in South Africa. It has unrecognised, but undoubtedly significant implications for the health service and patients affected by…
- Trial name
- GRIT (NCT03854591)
- Testing
- No intervention
- Where
- South Africa
- Volunteers
- 138 people
- Sponsor
- University of Cape Town
Polytrauma
Inflammatory Markers in Trauma Patient Outcomes
It is unknown whether early modulation of inflammatory cytokines is associated with improved patient outcomes, reduced narcotic requirements in orthopaedic patient population, and improved patient subjective pain after hospital…
- Trial name
- NCT03671746
- Testing
- Ketorolac, Saline Solution
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Arun Aneja
Hemorrhagic Shock
Efficacy, Safety of Solution Containing Hyperosmolar Sodium Lactate Infusion for Resuscitation of Patients With Hemorrhagic Shock
Indication: Resuscitation in pts with hemorrhagic shock due to multiple injuries Prospective, open label RCT in pts. with traumatic hemorrhagic shock in RS Hasan Sadikin Hospital, Indonesia. PI: Dr.
- Trial name
- NCT01433276
- Testing
- Hyperosmolar sodium lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 71 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Multiple Trauma, Traumatic Brain Injury
Spinal Clearance Study: Expediting the Spinal Clearance Process in the Major Trauma Patient
The Alfred Hospital receives approximately 40% of the major trauma patients in Victoria, all of whom are at risk for spinal injuries.
- Conditions
- Multiple Trauma, Traumatic Brain Injury, Spinal Injuries
- Trial name
- NCT00163826
- Where
- Australia
- Volunteers
- 299 people
- Sponsor
- Bayside Health
Multiple Trauma
Inflammatory Response After Muscle and Skeleton Trauma
The purpose of this study is to determine the inflammatory response after multiple trauma in humans.
- Trial name
- IRAMST (NCT00710411)
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Polytrauma
25-Year Experience With Polytraumatized Patients in a Level 1 Trauma Center
In this study patients who were admitted to our hospital with critical injuries were enrolled retrospectively from January 1992 to December 2019.
- Trial name
- NCT04723992
- Testing
- retrospective analysis
- Where
- Austria
- Volunteers
- 1,400 people
- Sponsor
- Medical University of Vienna
Polytrauma
Analysis of Urogenital Injuries in Polytraumatized Patients
Urogenital injuries occur in approximately 5-10 % of all severly injured patients. The literature lacks a thorough investigation into the mechanisms of trauma, the analysis of the whole urogenital tract and especially the…
- Trial name
- NCT05074095
- Testing
- retrospective analysis
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Polytrauma
Development of Clinical Decision Support System for Severe Patients With Polytrauma
The goal of this observational study is to develop a Clinical Decision Support System for severe patients with polytrauma. The main questions it aims to answer are: Is it possible to predict the development of systemic…
- Trial name
- NCT06323096
- Where
- Kazakhstan
- Volunteers
- 500 people
- Sponsor
- Semey State Medical University
Multiple Trauma
Proteomics in Multiple Trauma to Identify Organ Failure
To analyse differences in protein expression in multiple trauma patients for identification of potential biomarkers to predict organ dysfunction.
- Trial name
- NCT02030327
- Where
- Germany
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Köln
Kidney Injury
Acute Kidney Injury in Poly Trauma Patients
The aim of this study is to identify the incidence and the factors associated with acute kidney injury in adult poly trauma patients
- Trial name
- NCT06108765
- Volunteers
- 100 people
- Sponsor
- Assiut University
Polytrauma, Resuscitation, Trauma Patients
Pv-aCO₂ Gap-Guided Resuscitation in Adult Polytrauma Patients: A Prospective Randomized Controlled Trial
dult patients with multiple traumatic injuries admitted to the ICU from the operating room, emergency department, or hospital wards who meet the study criteria will be included after obtaining informed consent from the patient or…
- Trial name
- NCT07480655
- Testing
- Veno-arterial Carbondioxide gap, Conventional resuscitation end points
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Pakistan Institute of Medical Sciences
Vitamin D Deficiency, Polytrauma
Vitamin D and Bone Homeostasis in Ortho Polytrauma Patients
Although vitamin D is known to play a major role in multiple organ functions in healthy adults, including bone homeostasis, its role in the unique population of orthopaedic polytrauma patients has not been well described.
- Conditions
- Vitamin D Deficiency, Polytrauma, Orthopedic Disorder
- Trial name
- NCT03066817
- Testing
- Ergocalciferol 8000 IU/ML Oral Liquid [DRISDOL], Propylene Glycol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- New York City Health and Hospitals Corporation
Multiple Trauma, Pain, Acute
Intranasal Ketamine Versus Intranasal Fentanyl
Abstract Background: Given the inadequate control of pain in patients with injury that refer to the emergency departments, the rapid onset of action of intranasal administration in pain management, and the avoidance of…
- Trial name
- NCT04414800
- Testing
- Ketamine, Fentanyl
- Where
- Iran
- Volunteers
- 125 people
- Sponsor
- Isfahan University of Medical Sciences
Polytrauma Patients
The Kampala Trauma Score in the Outcome of Polytrauma Patients
The goal of this observational study is to learn about the predictive value of the Kampala Trauma Score in Egypt. The main question it aims to answer is: How does the performance of the Kampala Trauma Score compare to the…
- Trial name
- NCT06699641
- Volunteers
- 110 people
- Sponsor
- Assiut University
Acute Pain, Multiple Trauma
Ketamine Patient-Controlled Analgesia for Acute Pain
This study will compare ketamine and hydromorphone as alternative patient-controlled interventions for trauma-related pain. Patients receiving ketamine PCA are expected to require less total and breakthrough opioid and to have…
- Conditions
- Acute Pain, Multiple Trauma, Fractures
- Trial name
- NCT02062879
- Testing
- Ketamine, Hydromorphone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University
Multiple Trauma
INVITE Study: Invasive Instrumentation in Trauma Patients in the Shock Room
This study is an online survey asking for invasive instrumention in trauma patients of an emergency department
- Trial name
- INVITE (NCT02666677)
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- Universitätsklinikum Köln