Clinical trials: Poor Memory
Dementia
Perceptions Regarding Investigational Screening for Memory Problems in Primary Care
The purpose of this study is to conduct a cross-sectional survey of primary care patients to better understand their perceptions of the risks and benefits of a screen and subsequent diagnostic confirmation of dementia.
- Trial name
- PRISM-PC (NCT00759252)
- Where
- United States
- Volunteers
- 954 people, healthy volunteers welcome
- Sponsor
- Indiana University
Age-associated Memory Impairment
TMS for Investigating Memory Facilitation
The aim of this study is to investigate the effects of Transcranial Magnetic Stimulation (TMS) following a Paired Associative Stimulation (PAS) protocol on the memorization capacity of elderly individuals.
- Trial name
- NCT05462782
- Testing
- Transcranial Magnetic Stimulation (TMS) Cone Coil
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Memory Deficit
To Drill or Not to Drill: Do Memory Drills Help Train the Ability to "Remember to Remember" in Veterans
The goal of this clinical trial is to memory drilling works in improving the ability to remember to do something later in treatment-seeking veterans.
- Trial name
- PMIS (NCT06656637)
- Testing
- Memory Drilling, Compensatory Strategies, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Los Angeles
Schizophrenia
The Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on Working Memory
Deficits in working memory (WM) performance are the most significant cognitive impairments in schizophrenia (SCZ). It has also been shown that WM performance is contingent on the cortex synchronization, a process that relies on…
- Trial name
- NCT01494623
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Intellectual Disability, Neurodevelopmental Disorders
Physical Activity and Community EmPOWERment Project
Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease…
- Conditions
- Intellectual Disability, Neurodevelopmental Disorders, Autism Spectrum Disorder, Down Syndrome
- Trial name
- PACE (NCT06740162)
- Testing
- PACE Program
- Where
- 2 sites in United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Focal Epilepsy, Temporal Lobe Epilepsy
Spatial Scene Recognition Memory in Epilepsy Surgery
This study investigates the anatomical and physiological basis of spatial scene recognition memory in patients with temporal lobe epilepsy and temporal lobe lesions.
- Conditions
- Focal Epilepsy, Temporal Lobe Epilepsy, Medically Refractory Epilepsy, Memory Disorders
- Trial name
- NCT07580183
- Testing
- Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimaging and Neuropsychological Assessment (Aim I)
- Where
- 2 sites in United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Stroke, Vascular Dementia
Aricept to Improve Functional Tasks in Vascular Dementia
Medications for memory improvement are available but they may not actually improve the ability to do real world tasks. The purpose of this research study is to determine if a medicine used to treat memory problems…
- Conditions
- Stroke, Vascular Dementia, Memory Deficits
- Trial name
- NCT00457769
- Testing
- Donepezil and self-generated memory training, Donepezil and experimenter-administered memory training
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Kessler Foundation
Alzheimer Dementia, Alzheimer Disease
MAD Phase I Study to Investigate Contraloid Acetate
This is a single-center multiple-ascending-dose clinical trial assessing the safety and tolerability of oral dosing of Contraloid acetate in healthy volunteers.
- Trial name
- NCT03955380
- Testing
- Contraloid
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Dieter Willbold
Eosinophilia-Myalgia Syndrome
L-5-HTP-Related EMS
In 1989 more than 1500 people who took the dietary supplement L-tryptophan for insomnia and depression developed eosinophilia myalgia syndrome (EMS)-a potentially fatal disease characterized by an excess of a type of white blood…
- Trial name
- NCT00001918
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Mental Health (NIMH)
Mild Cognitive Impairment, Alzheimer Disease
Working Memory Training in Older Adults With Mild Cognitive Impairment : Impacts on Cognition and Ecological Activities
Older adults with Mild Cognitive Impairment (MCI) have an increased risk of developing dementia but do not meet the criteria for dementia.
- Trial name
- APT-II (NCT04606953)
- Testing
- Attention Process Training (APT-II)
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University of Paris 5 - Rene Descartes
Pediatric Iron Deficiency, Anemia
Choline and Iron Deficiency
BACKGROUND: Iron deficiency limits the neurodevelopmental potential of more than 200 million children each year. Iron therapy is typically started when iron deficiency anemia is first diagnosed after screening for anemia or…
- Trial name
- NCT06527391
- Testing
- choline bitartrate
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Minnesota
Acute Exercise, Caffeine Withdrawal
The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation
To determine the effects of moderate intensity exercise and caffeine on working memory in deprived caffeine consumers.
- Conditions
- Acute Exercise, Caffeine Withdrawal, Memory Deficits
- Trial name
- NCT05170464
- Testing
- Acute Exercise, Caffeine Powder
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Age-Related Memory Disorders
A Safety and Efficacy Study of Ispronicline (TC-1734-112) in Subjects With Age Associated Memory Impairment (AAMI)
The purpose of this Phase II study is to evaluate the efficacy and safety of ispronicline (TC-1734-112) compared to placebo (inactive substance pill) in patients with age associated memory impairment (AAMI).
- Trial name
- NCT00109564
- Testing
- ispronicline (nicotinic acetylcholine receptor agonist)
- Where
- 15 sites in United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Targacept Inc.
Mild Cognitive Impairment
Network-guided TMS in Early Alzheimer's Disease
The proposed research will test a novel network-based neurostimulation approach using MRI-derived measures of brain connectivity to establish target sites for neurostimulation and test for the enhancement of memory function…
- Trial name
- NetTMS (NCT04549155)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Duke University
Anxiety, Stress
An Exploratory Investigation of a Supplement to Promote Cognitive Health Benefits
The Smart Supplement has 20 vitamins and minerals that have strong track records of demonstrating positive health effects, both physiologically and cognitively.
- Conditions
- Anxiety, Stress, Memory Deficits, Cortisol Overproduction
- Trial name
- NCT05523115
- Testing
- Heights Smart Supplement
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Heights
Hypertension, Stress, Psychological
Stress and Blood Pressure Management for Caregivers
Due to health and wealth disparities, no demographic group is more at risk than African American women for the double jeopardy of stress from caregiving for persons living with dementia (PLWD) and stress associated with…
- Trial name
- Stress/HTN (NCT05734638)
- Testing
- MIM-DASH, MIM Only, DASH Only
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ohio State University
Subjective Memory Complaints
Effects of Fermented Codonopsis Lanceolata on Improvement in Cognitive-Bio-Markers of Cognitive Functions
The objective of this study is to demonstrate the cognitive enhancement effect and safety of Fermented Codonopsis lanceolata, using the cognitive and clinical indicators (e.g.
- Trial name
- NCT03439098
- Testing
- Fermented Codonopsis lanceolata 525mg, Fermented Codonopsis lanceolata 1050mg
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Ewha Womans University
Parkinson Disease, Memory Impairment
Dopaminergic Mechanism of Memory Impairment in Parkinson's Disease
The cognitive impairment of Parkinson's disease is non amnestic, which is characterized by working memory impairment and executive dysfunction.
- Trial name
- NCT04968613
- Testing
- Madopar monotherapy, senfrol monotherapy
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
THC
Pilot fMRI Studies of Aging-Related Effects of THC
The purpose of this study is to begin investigating acute impairment of various forms of memory and learning by Tetrahydrocannabinol (THC) in cannabis (CNB) compared to placebo, in a 2-session per subject double-blind, random…
- Trial name
- NCT06647524
- Testing
- THC
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Multiple Sclerosis
Improving Memory in Patients With Multiple Sclerosis
People with multiple sclerosis (MS) suffer from cognitive and other brain problems. This study will examine the effectiveness of the drug donepezil and of sugar water for enhancing memory in individuals with MS.
- Trial name
- NCT00062972
- Testing
- donepezil, glucose
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)