Clinical trials: Population
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Healthy
Increasing Infant Preventive Health Service Delivery in an Inner City Population
The study hypothesis is that case management using patient navigators ("promatoras" in the Latino community) will increase infant immunization rates and use of well child care in an inner city population of low socioeconomic…
- Trial name
- NCT00221507
- Testing
- Reminder-Recall-Outreach, Case Management, Patient Navigator
- Where
- United States
- Volunteers
- 823 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Constipation
TD-1211 Single-Dose Study in Elderly and Young Healthy Subjects
The purpose of this study is to measure the way in which TD-1211 is absorbed and eliminated by the body and to evaluate whether it is safe and well tolerated.
- Trial name
- NCT01655771
- Testing
- TD-1211 Dose 1, TD-1211 Dose 2
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Glycyx Therapeutics
Stroke, Hemiparesis
Telerehabilitation Through Serious Games in Virtual Reality in a Stroke Population (AutoRReVi)
After a stroke, individuals present with motor and/or cognitive impairments. These impairments limit activity, restrict participation and affect quality of life.
- Conditions
- Stroke, Hemiparesis, Cognitive Impairment, Healthy Subjects
- Trial name
- AutoRReVi (NCT04694833)
- Testing
- Motor and cognitive virtual reality-based assessments, Motor and cognitive virtual reality-based serious games
- Where
- Belgium
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Substance Abuse, Families
Family-Based Drug Services for Young Disaster Victims
This protocol seizes this rare scientific opportunity to test an integrative family based model to address youths' coexisting substance abuse and trauma in the wake of Hurricane Katrina.
- Conditions
- Substance Abuse, Families, Trauma
- Trial name
- Katrina (NCT01859000)
- Testing
- Multidimensional Family Therapy, Group CBT
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Miami
Healthy
Safety and Tolerability of Lu AG06474 in Healthy Young Men
The purpose of this study is to investigate the safety and tolerability of Lu AG06474 and what the body does to Lu AG06474 after swallowing single doses of the drug.
- Trial name
- NCT05003687
- Testing
- Lu AG06474
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Emotional Eating, Emotion Regulation
ACT-Based Group Therapy and Mobile Application Intervention for Emotional Eating
This study aims to evaluate the effects of an Acceptance and Commitment Therapy (ACT)-based group therapy program, combined with an ACT-based mobile app, on emotional eating, emotion regulation, and psychological flexibility in…
- Conditions
- Emotional Eating, Emotion Regulation, Overweight, Psychological Flexibility
- Trial name
- ACT-EE (NCT07559552)
- Testing
- ACT-Based Group Therapy, ACT-Based Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Chronic Kidney Failure, Chronic Kidney Disease stage3
Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis.
The evolution of chronic kidney disease (CKD) causes a systemic upheaval on the body and a deep fatigue is very often described by patients (50-70% of the patients) even before the start of dialysis (pre-dialysis).
- Conditions
- Chronic Kidney Failure, Chronic Kidney Disease stage3, Chronic Kidney Disease, Stage 4 (Severe), Chronic Kidney Disease Stage 5
- Trial name
- PIONNIER (NCT03998917)
- Testing
- Discrimination of neuromuscular alterations protocol
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier le Mans
Colorectal Cancer Screening Fecal Immunochemical Test
Multi-center Application of Quantitative FIT Technology in Colorectal Cancer Screening
In order to control the incidence of colorectal cancer, improve the level of early diagnosis and early warning the occurrence of colorectal cancer, it is very necessary for us to explore the threshold value of FIT positive…
- Trial name
- NCT04959617
- Testing
- Quantitative Fecal Immunochemical Test (qFIT)
- Where
- China
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Covid19
Relative Bioavailability, Safety, and Tolerability of Single-dose Sotrovimab Injection in Adults (COSMIC)
This clinical pharmacology study will evaluate the relative bioavailability, safety, and tolerability of two different concentrations of sotrovimab injections administered at different injection sites in male or female healthy…
- Trial name
- COSMIC (NCT05280717)
- Testing
- sotrovimab
- Where
- 10 sites in United States
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Vir Biotechnology, Inc.
Anemia, Iron-deficiency
Association Between Anaemia and Handgrip Strength in Female Planned for Major Surgery and the Effect of Intravenous Iron on Handgrip Strength
This is a sub-study parallel to ProPBM : A Randomised Control Trial Comparing a Modified Patient Blood Management Protocol Against Standard Care for Patients Undergoing Major Surgery (NCT03888768).
- Conditions
- Anemia, Iron-deficiency, Patient Blood Management, Iron Deficiency Anemia
- Trial name
- NCT04642521
- Testing
- Jamar hydraulic hand dynamometer
- Where
- Malaysia
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Ageing, Blood Flow Restriction
Comparing Vascular Responses to Resistance Exercise with and Without Blood Flow Restriction in Young and Older Adults
Aging leads to declines in functional capacity and effort tolerance. Muscle strength remains stable from ages 25 to 50 but declines significantly after age 60, affecting activities like stair climbing and walking, reducing…
- Trial name
- HOLD TIGHT (NCT06596304)
- Testing
- Low intensity-resistance training with lower limb blood flow restriction, High Intensity Resistance Training
- Where
- 2 sites in Portugal
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Relapse Remitting Multiple Sclerosis
Study to Assess the Effect of Ofatumumab in Treatment Naïve, Very Early RRMS Patients Benchmarked Against Healthy Controls.
This study evaluates the impact of ofatumumab in Relapsing Remitting Multiple Sclerosis (RRMS) participants that are very early in the course of their disease using clinical and magnetic resonance imaging (MRI) outcomes.
- Trial name
- AGNOS (NCT05084638)
- Testing
- Ofatumumab
- Where
- 36 sites in United States, Puerto Rico
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Pulpitis, Caries Active
Hydraulic Cements in Partial Pulpotomy
This study is a randomized clinical trial that compares two types of hydraulic cements used in partial pulpotomy procedures for permanent teeth affected by deep decay and pulp inflammation.
- Trial name
- NCT06881615
- Testing
- MTA PLACEMENT FOR PP, PUTTY PLACEMENT FOR PP
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Diphtheria, Tetanus
To Evaluate the Immunogenicity and Safety of DTaP-IPV Vaccine Administered as a Boosting Dose to Healthy Children of 4-6 Years
The study objective is to assess the immunogenicity and safety of DTaP-IPV combination vaccine administered as a boosting dose to healthy 4 to 6-year-old children who received three doses of primary immunization against…
- Conditions
- Diphtheria, Tetanus, Pertussis, Poliomyelitis
- Trial name
- Aladdin (NCT04618640)
- Testing
- DTaP-IPV combination vaccine
- Where
- 26 sites in South Korea
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Boryung Biopharma Co., Ltd.
Cholera, Diarrhea
Mass Oral Cholera Vaccination in Zanzibar
The purpose of this study is to conduct cholera vaccinations in high-risk populations in Zanzibar in order to estimate herd protection conferred by the vaccine,estimate effectiveness of the vaccine, and describe the interaction…
- Trial name
- NCT00709410
- Testing
- rBS-WC vaccine
- Where
- Tanzania
- Volunteers
- 51,151 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Vitamin D Insufficiency, Vitamin D Deficiency
Vitamin D Inadequacy in Rural Populations, Evaluation of Correction by Food Supplementation
The purpose of the research is to describe vitamin D levels and bone status in a rural Wisconsin population. It is probable that individuals of varying age and ethnicity require different amounts of D to achieve optimal status.
- Trial name
- NCT00690417
- Testing
- Cholecalciferol (vitamin D3)
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Coronary Heart Disease
Rapid Engagement for Solutions to Population and Outcomes Through Networked Dialogue for Coronary Heart Disease
Cardiometabolic diseases are major causes of morbidity and mortality in the state of Wisconsin and are expected to pose an increasing burden over the next few decades.
- Trial name
- RESPOND (NCT07260552)
- Testing
- Polygenic risk score
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Herpes Zoster
Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population
Background: Shingles is a painful, blistering rash caused by the same virus that causes chickenpox. Shingrix is a vaccine approved to prevent shingles in healthy adults over age 50 and in immunocompromised adults over age 18.
- Trial name
- NCT05580458
- Testing
- Shingrix
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Influenza, Virus Diseases
Group Study of the Safety of and Immune Response to a Single Dose of Bird Flu Vaccine (H7N3) in Healthy Adults
Over the past decade, avian influenza (AI) has become a major health concern. The development of safe and effective vaccines against avian strains that infect people is important.
- Trial name
- NCT00853255
- Testing
- Live Influenza A Vaccine H7N3 (6-2) AA ca Recombinant (A/chicken/British Columbia/CN-6/2004 x A/Ann Arbor/6/60 ca)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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