Clinical trials: Population Study
Hepatic Impairment, Healthy Volunteers
A Study to Understand How the Study Medicine (PF-07081532) is Processed in People With Liver Dysfunction
The purpose of this study is to understand the effects of liver functional impairment on the study medicine (PF-07081532). People with liver functional impairment may process the study medicine differently from healthy people.
- Trial name
- NCT05478603
- Testing
- PF-07081532
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Prevention of Meningococcal Infection
Persistence of Antibody Response to N. Meningitidis Group C in Children
Persistence of Antibody Response to N. meningitidis Group C in Children
- Trial name
- NCT00316654
- Testing
- Meningococcal C conjugate vaccine
- Where
- 2 sites in Poland, Spain
- Volunteers
- 489 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Tolerance, Safety Issues
Buck Institute Ketone Ester RCT
This study is to investigate the tolerability and safety of a ketone promoting ingredient, called a ketone ester (KE), in healthy older adults.
- Conditions
- Tolerance, Safety Issues, Aging
- Trial name
- BIKE (NCT05585762)
- Testing
- Ketone ester
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Buck Institute for Research on Aging
Male Reproductive Problem
Effect of Formal Letter of Invitation on Male Partner Involvement at Antenatal Care Clinic
Prevention of mother to child transmission (PMTCT) of human immune deficiency virus (HIV) program requires great male participation in achieving a sustained reduction of mother-to-child transmission of HIV.
- Trial name
- NCT06171503
- Testing
- letter of invitation on MI in PMTCT service
- Where
- Ethiopia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Jimma University
Gingivitis, Dental Plaque
Efficacy of Electric 3D Versus Manual Toothbrushes in Patients With Fixed Orthodontic Appliances
This study evaluates if electric toothbrushes with a 3D action (rotation / oscillation and pulsation) are more effective than manual toothbrushes in removing plaque and reducing gingival inflammation in patients under orthodontic…
- Trial name
- NCT02699931
- Testing
- Electric3D, Manual
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Hepatic Impairment
A Study of JNJ-53718678 in Participants With Hepatic Impairment
The main purpose of the study is to evaluate the pharmacokinetc (PK) of a single oral dose of JNJ-53718678 in participants with varying degrees of impaired hepatic function (mild, moderate, and severe) when compared with…
- Trial name
- NCT04332523
- Testing
- JNJ-53718678
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy Male Subjects
Compare the Pharmacokinetics and Safety of BAT3306 Injection Versus KEYTRUDA® Administered in Healthy Male Subjects
to Compare the Pharmacokinetics and Safety of BAT3306 versus KEYTRUDA® Administered in Healthy Male Subjects
- Trial name
- NCT06111196
- Testing
- Recombinant Humanized Anti-PD-1 Monoclonal Antibody Solution for Injection, Pembrolizumab injection
- Where
- China
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Bio-Thera Solutions
Healthy
AZD5985 Single Ascending Dose Study
The aims of this study are to assess the safety, tolerability and pharmacokinetics of single ascending oral doses of AZD5985 in healthy male subjects.
- Trial name
- NCT00967356
- Testing
- AZD5985
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Vaccination Reaction
Longitudinal Evaluation of Antibody Kinetics of Vaccinated Patients With Non-mandatory Vaccine Following Administration of a Non-public Marketed Vaccine in the General Population, Real-life Study
The study would make it possible to document more explicitly the evolution of antibody titers at following a non-public vaccination over a large post-vaccination period in the French population .
- Trial name
- ELCAV (NCT06373510)
- Testing
- Blood collection
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- CerbaXpert
Influenza
Safety Study of CSL Limited's Influenza Virus Vaccine in the Paediatric Population Aged >= 6 Months to < 18 Years
A Phase IV, Open Label, Multi-Centre Study to Evaluate the Safety and Tolerability Profile of CSL Limited's Influenza Virus Vaccine in a Paediatric Population Aged >= 6 Months to < 18 Years
- Trial name
- NCT00825162
- Testing
- CSL Limited Influenza Virus Vaccine
- Where
- 7 sites in Australia
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- Seqirus
Pneumococcal Vaccines
Safety, Tolerability, and Immunogenicity Study of a 31-Valent Pneumococcal Conjugate Vaccine (VAX-31) in Adults
The objective of the study is to evaluate the safety, tolerability and immunogenicity of a single injection of VAX-31 at 3 dose levels compared to Prevnar 20™ (PCV20) in adults 50 to 64 years of age in Stage 1.
- Trial name
- NCT06151288
- Testing
- 31 valent pneumococcal conjugate vaccine, 20 valent pneumococcal conjugate vaccine
- Where
- 25 sites in United States
- Volunteers
- 1,015 people, healthy volunteers welcome
- Sponsor
- Vaxcyte, Inc.
Feeding Difficulties, Feeding Problems
Long-Term Effect of Online Occupational Therapy-Based Parent Training on Feeding Problems in Infants
This study type is a clinical trial (randomized controlled longitudinal study). The primary purpose is to determine whether an online occupational therapy-based parent training program can prevent or reduce feeding problems…
- Conditions
- Feeding Difficulties, Feeding Problems, Food Neophobia
- Trial name
- NCT07050927
- Testing
- Online occupational therapy group training
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Healthy Diet
Nutritional Study on the Beneficial Effects of Canned Fish Consumption on Healthy Adult Population
There is sufficient evidence on the beneficial effects of fish consumption on health, mainly associated with the content of omega-3 polyunsaturated fatty acids (EPA and DHA) present mainly in blue fish.
- Trial name
- TUNACAN (NCT05213273)
- Testing
- nutritional guidelines to promote healthy diet and increase fish intake
- Where
- Spain
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Sara Arranz Martinez
Brugada Syndrome, Long QT Syndrome 3
Worm Study: Modifier Genes in Sudden Cardiac Death
Quest for modifier genes associated with ventricular arrhythmias in presence of a cardiac sodium channel gene (SCN5A-delPhe1617) mutation.
- Trial name
- NCT02014961
- Testing
- Dermal biopsy, Gastro-intestinal questionnaire, Whole-exome sequencing
- Where
- Netherlands
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy Participants
A Study to Assess the Effect of Itraconazole, Phenytoin and Gemfibrozil on the Drug Levels of BMS-986166 in Healthy Participants
The purpose of this study is to evaluate the effect of itraconazole, phenytoin and gemfibrozil on the drug levels of BMS-986166 and its active metabolite BMT-121795.
- Trial name
- NCT04956627
- Testing
- BMS-986166, Itraconazole, Extended Phenytoin Sodium
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
pH
The Impact of Anti- Asthmatic Medications on Salivary pH and Dental Caries Pattern in a Group of Egyptian Children With Bronchial Asthma
The impact of Anti- Asthmatic medications on salivary pH and dental caries pattern in a Group of Egyptian Children with Bronchial Asthma.
- Trial name
- NCT03877874
- Testing
- Aironyl syrup(Terbutaline sulfate) + Epidrone syrup(Dexamethone)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Microbiota
Effects of Resistant Potato Starch on the Gut Microbiota
This was a randomized, double-blind, three-arm, parallel group clinical trial, which assessed the shifts that occur in microbial populations after four weeks of supplementation with resistant potato starch (SolnulTM) at two…
- Trial name
- NCT05242913
- Testing
- Resistant Potato Starch
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MSP Starch Products Inc.
Healthy Volunteer
Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A
The purpose of this study is to evaluate the effect of the following index inhibitors or inducers of CYP2C8 and/or CYP3A on the single-dose pharmacokinetics (PK) of ozanimod and its major active metabolite, CC112273, in healthy…
- Trial name
- NCT03624959
- Testing
- Ozanimod, Gemfibrozil, Itraconazole
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Celgene
Sleep Deprivation
Pharmacodynamic Profile of SPD489 in Healthy Adult Males Undergoing a Nocturnal Period of Acute Sleep Loss
This is a double-blind, single center, parallel group, placebo and active comparator, controlled study to characterize the wake promoting effects of single doses of SPD489 in healthy adult male undergoing acute sleep deprivation.
- Trial name
- NCT01096680
- Testing
- SPD489 20 mg, SPD489 50 mg, SPD489 70 mg
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Shire
Trisomy 21
Study of High Risk Non Invasive Prenatal Test Population
The investigator want to study the population of high risk (over 1/50) of Trisomy 21. According to french guidelines, these patients needs to have a invasive test (such as amniocentesis) but some patients prefer to have a Non…
- Trial name
- NCT04737070
- Testing
- Prenatal test for Trisomy 21 screening
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
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