Clinical trials: Positive Affect
Healthy Volunteer
A Study to Find Out How Multiple Doses of BIIB091 Affect the Electrical Activity of the Heart in Healthy Participants
In this study, researchers will learn how the heart reacts to multiple doses of BIIB091 in healthy participants. In previous studies looking at BIIB091, researchers have found that a certain range of doses can cause changes in…
- Trial name
- NCT06574828
- Testing
- BIIB091, Moxifloxacin
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Biogen
Meditation, Pain
Study of Affect Induction for Lab Induced Pain in Healthy Undergraduates
The goal of this clinical trial is to test if a mindfulness-enhanced positive affect induction (MPAI) works well to reduce pain intensity and pain unpleasantness from a cold water pain test in undergraduate college students who…
- Conditions
- Meditation, Pain, Mindfulness, Affect
- Trial name
- NCT05619419
- Testing
- Mindfulness-enhanced positive affect induction, Breathing Meditation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alcoholism, Healthy
The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics
This study was designed to learn more about the areas of the brain involved in the experience of positive and negative emotions.
- Trial name
- NCT00001675
- Where
- United States
- Volunteers
- 1,194 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Technology Use, Positive Affect
Best Possible Self-Tech for Middle Schoolers
The goal of this pilot clinical trial is to learn if a single-session writing exercise (i.e., Best Possible Self-Tech) can improve positive affect and prosocial technology use in a community sample of eighth graders.
- Trial name
- NCT07540819
- Testing
- Best Possible Self-Tech
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Healthy
A Study in Healthy People to Measure How Different Doses of Verducatib Affect the Heart
The main objective of this trial is to evaluate the effects of verducatib in the range of therapeutic to supra-therapeutic exposures on the QT/QTc-interval and other ECG parameters
- Trial name
- NCT07760246
- Testing
- Verducatib, Moxifloxacin
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy People to Test How Vicadrostat Affects the Heart
The main objective of this trial is to investigate the effect of vicadrostat on the heart compared with placebo in healthy male and female volunteers.
- Trial name
- NCT07513207
- Testing
- Vicadrostat, Moxifloxacin
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Positive Affect, Mindfulness
Skills to Enhance Positivity in Young Adults
The goal of this study is to test the feasibility and acceptability of a positive affect intervention for suicide in a population of young adults.
- Conditions
- Positive Affect, Mindfulness, Gratitude, Savoring
- Trial name
- STEP YA (NCT06621992)
- Testing
- Skills to Enhance Positivity, Treatment as Usual
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Pain
Do Emotions Affect Mechanical Pain Thresholds?
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds.
- Trial name
- DEAMPT (NCT06074575)
- Testing
- Emotion induction
- Where
- Sweden
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Stress, Anxiety
Effects of High Ventilation Breathwork With Retention (HVBR) on Health
The investigators are conducting a randomised-controlled trial comparing high ventilation breathwork with retention (HVBR) to a breathwork placebo (paced breathing at 15breaths/min with brief retentions).
- Conditions
- Stress, Anxiety, Depressive Symptoms, Mental Wellbeing
- Trial name
- NCT06064474
- Testing
- High ventilation breathwork with retention (HVBR)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Adolescent Behavior, Stress Reduction
CEDARS Intervention: A Coping, Emotional Development, & Stress Reduction Intervention
Using an adapted stress-reduction intervention called the CEDARS, the investigators will pilot the intervention in adolescents (N=40) to determine the feasibility and acceptability of CEDARS implementation and to investigate…
- Conditions
- Adolescent Behavior, Stress Reduction, Adverse Childhood Experiences, Positive Attitude
- Trial name
- CEDARS (NCT04958694)
- Testing
- CEDARS
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Self Efficacy, Health Behavior
RCT for Evaluation of Online Social Networking Intervention in Smoking Cessations
The proposed RCT evaluates the efficacy of the aforementioned novel 2-month online smoking cessation intervention in increasing 7-day point prevalence quit rate over a 6-month follow-up period among Chinese adult smokers in Hong…
- Trial name
- NCT03387800
- Testing
- Basic health education messages, WeChat interactive peer support group
- Where
- Hong Kong
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Aging Well, Positive Affect
Savor-Aging: the Art of Savoring Positive Emotions
This study is part of the larger project to promote positive aging (PNRR Age-IT Project) in the elderly through the amplification of positive experiences and emotions.
- Trial name
- NCT06842628
- Testing
- Savoring, Positive Emotional Induction
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Burnout, Professional, Negative Affect
Floatation Experience in Nurses and Physicians
The goal of this observational study is to monitor the floatation experience and continue the program as long as deemed important.
- Conditions
- Burnout, Professional, Negative Affect, Positive Affect, Wellbeing
- Trial name
- NCT05977894
- Testing
- Reduced Environmental Stimulation Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Healthy Aging, Elderly (People Aged 65 or More)
Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals
This research was planned to determine the effect of structured sandplay activities on positive and negative affect and levels of meaning in life in elderly individuals.
- Trial name
- NCT07735351
- Testing
- Sandplay-Act. Older: Structured Sandplay Activity for Older Individuals, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Happiness, Self Efficacy
Strengths to Grow: An Online Parenting Resource
Research suggests that strength-based parenting programs can enhance family well-being, but the current formats of these programs (e.g., in-person workshops) are not accessible to many families.
- Conditions
- Happiness, Self Efficacy, Positive Affect
- Trial name
- NCT05535881
- Testing
- Strengths to Grow Program
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Mental Health Wellness 1, Positive and Negative Affect
Effects of a Relaxation and Guided Imagery Intervention in School Context
Specific aims - To test the effects of a relaxation and guided imagery intervention with socioemotional learning content on a range of socioemotional, physiological, cognitive and academic outcomes of school-aged children…
- Conditions
- Mental Health Wellness 1, Positive and Negative Affect, Social Skills, Happiness
- Trial name
- MR (NCT06101225)
- Testing
- MindRegulation Intervention, Relaxation, Waiting List Control Group
- Where
- Portugal
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidade Autónoma de Lisboa
Geriatric, Chronic Pain
Positive Affect as a Source of Resilience for Adults in Chronic Pain
Fibromyalgia syndrome (FMS) is a chronic musculoskeletal condition characterized by widespread pain and tenderness, and often accompanied by impaired physical functioning, depressed mood, as well as deficits in positive affect…
- Trial name
- LARKSPUR (NCT04869345)
- Testing
- LARKSPUR
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Stress, Dementia
Life Enhancing Activities for Family Caregivers
Life Enhancing Activities for Family Caregivers is a six-week program designed to increase positive affect in people who care for a family member with dementia.
- Conditions
- Stress, Dementia, Affect
- Trial name
- LEAF (NCT01825681)
- Testing
- Positive Affect
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Depression
Positive Affect Treatment for Adolescents With Early Life Adversity
Youth exposed to early life adversity (ELA) are known to be at greater risk for depression and suicidality and account for almost half of the youth suffering from psychiatric diseases today.
- Trial name
- PAT4ELA (NCT06273137)
- Testing
- Positive affect treatment, Supportive psychotherapy (SUP)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Disordered Eating Behaviors, Body Image Disturbance
Positive Mirror Exposure for Body Image in Female Students With Disordered Eating
This study aims to examine the efficacy of repeated positive mirror exposure in improving body image and emotional affect among female university students with disordered eating symptoms.
- Trial name
- NCT07558161
- Testing
- Positive Mirror Exposure
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kinnaird College for Women