Clinical trials: Positron-Emission Tomography
Neoplasms, Nervous System Disease
Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients
Background: Neurofibromatosis type II (NF2) is associated with tumors of the nerves, brain, and spinal cord. Most people with NF2 develop vestibular schwannomas, or tumors on the hearing and balance nerves.
- Conditions
- Neoplasms, Nervous System Disease, Vestibular Disease
- Trial name
- NCT01222728
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Lymphoma, Non-Hodgkin, Advanced Stage Diffuse Large B-Cell Non-Hodgkin's Lymphoma
Tailoring Treatment for B Cell Non-hodgkin's Lymphoma Based on PET Scan Results Mid Treatment
The purpose of this study is to assess whether patients who are likely to fail R-CHOP, as predicted by a mid-treatment PET scan, can have an improved outcome if switched to a standard salvage regimen R-ICE (rituximab, ifosfamide…
- Trial name
- LYTPET (NCT00324467)
- Testing
- Cyclophosphamide, Doxorubicin, Vincristine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- British Columbia Cancer Agency
Unspecified Adult Solid Tumor, Protocol Specific
PET and/or MRI Scans in Assessing Tumor Response in Patients Receiving Antiangiogenesis Therapy
RATIONALE: Diagnostic procedures, such as PET and MRI scans, may help to measure a patient's response to treatment. PURPOSE: This diagnostic trial is studying how well PET and/or MRI scans work in assessing changes in tumor blood…
- Trial name
- NCT00019565
- Testing
- magnetic resonance imaging, positron emission tomography, fludeoxyglucose F 18
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Breast Cancer
Evaluation of Data Obtained From Three Common Imaging Techniques: Positron Emission Tomography (PET-CT), Breast Ultrasound, and Magnetic Resonance Imaging (MRI) After Neoadjuvant Chemotherapy in Patients With Breast Cancer
Breast cancer is the most common and most deadly malignant tumor in women. In the case of invasive breast cancer, cancer cells have invaded the tissues surrounding the tumor.
- Trial name
- NCT07441330
- Testing
- Breast ultrasound, MRI, TEP-TDM
- Where
- France
- Volunteers
- 42 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Brain Neoplasms
Study on Amino Acid Uptake in Brain Tumors
The purpose of this study is to determine the uptake of the amino acid O-(2-[F-18]Fluorethyl)-L-tyrosin (FET) in human brain tumors using positron emission tomography. A comparison to MRI and histopathological samples is used.
- Trial name
- NCT00204295
- Testing
- O-(2-[F-18]Fluorethyl)-L-Tyrosin (FET) - PET
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Muenster
Breast Carcinoma, Calcification
64 Cu-DOTA-alendronate PET Imaging in Localizing and Characterizing Breast Calcifications in Participants Before Undergoing Mastectomy
This early phase I pilot trial studies how well 64Cu-DOTA-alendronate positron emission tomography (PET) imaging work in localizing and characterizing breast calcifications (small calcium deposits) in participants before…
- Trial name
- NCT03542695
- Testing
- Computed Tomography, Copper Cu-64-DOTA-alendronate, Pharmacokinetic Study
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- City of Hope Medical Center
Glioblastoma
Evaluation of FLT PET and MRI as Imaging Biomarkers of Early Treatment Response in Patients With Glioblastoma
Glioblastoma is the most common primary malignant neoplasm of the adult brain. Even after multimodal therapy, outcomes remain poor, with a median survival of one year.
- Trial name
- NCT01880008
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Washington University School of Medicine
Parkinson's Disease
18F-DTBZ for l Diagnosis of Parkinson's Disease and Monitoring the Severity of Disease by VMAT2 PET Imaging
The primary objective of this protocol is to analyze the sensitivity and specificity of 18F-DTBZ PET to the differential diagnosis of Parkinson's Disease (PD) and normality.
- Trial name
- 8F-DTBZ (NCT01283347)
- Testing
- 18F-DTBZ
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Renal Cell Carcinoma, Neuroendocrine Tumours
[18]F-FAZA PET Imaging Study in Patients With Cancer of the Head & Neck, Lung, Renal Cell, Brain, Lymphoma and Neuroendocrine Tumours
Positron Emission Tomography (PET) is a Nuclear Medicine procedure that uses positron emitting radiolabeled tracer molecules to visualize biological activity.
- Trial name
- NCT00323076
- Testing
- 18F-FAZA PET Imaging
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- AHS Cancer Control Alberta
mCRPC (Metastatic Castration-resistant Prostate Cancer)
Four-Timepoint Multi-tracer PET Imaging to Characterize Metastatic prOstate Cancer Heterogeneity
Imaging modalities currently used in the clinics do not image cancer, but the effect ofncancer on bone (bone scan) or on the anatomy (CT-scan). Bone scan and CT-scan are therefore named conventional imaging (CI) modalities.
- Trial name
- 4TMPO (NCT07302763)
- Testing
- PET Tracer
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Frederic Pouliot
Healthy
A Study in Healthy Men to Investigate Uptake and Distribution of Lu AF88434 in the Brain
This study will investigate how much of Lu AF88434 will get into the blood and the brain in healthy men
- Trial name
- NCT04538014
- Testing
- Lu AF88434, [11C]-Lu AF88434
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Crohn Disease
Use of FDG PET/CT to Evaluate Crohn Disease
The purpose of this study will permit to determine the role of FDG PET/CT to diagnose Crohn Disease and recurrence of Crohn disease after having compared results of PET/CT's with results of exams routinely performed(colonoscopy…
- Trial name
- NCT00383344
- Testing
- FDG PET/CT
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Eric Turcotte
Inflammatory Bowel Disease (IBD), Disease Activity
Evaluation of Intestinal Lesions and Disease Activity in Inflammatory Bowel Disease Based on 18F-FAPI PET Imaging
The goal of this observational study is to evaluate the role and effect of 18F-FAPI PET imaging in the identification of intestinal lesions and the assessment of disease activity in inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Disease (IBD), Disease Activity, FAPI
- Trial name
- IBD，18F-FAPI (NCT06945549)
- Testing
- 18F-FAPI PET Imaging
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Coronary Artery Disease
Comparison of Cardiac Computed Tomographic Angiography (CTA) to Tc-99m Single Photon Emission Computed Tomography (SPECT)
Cardiovascular disease and ischemic heart disease is the #1 killer in Canada. Currently, Cardiac invasive catheterization angiography (CICA) is the gold standard for the assessment of the arteries in the heart.
- Trial name
- NCT00449943
- Testing
- Computed Tomographic Angiography, Myocardial Perfusion Imaging Scan
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Obesity, Heart Failure
Sex and Obesity: Effects on Heart Failure Study
Sex has a major impact on myocardial metabolism and blood flow. In those without heart failure men's hearts tend to use proportionally more glucose and women's hearts use more fat and have higher blood flow.
- Trial name
- NCT00776035
- Testing
- PET (Positron Emission Tomography), Echocardiogram, ^15O-water
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Washington University School of Medicine
Alzheimer Disease, Amyloid Beta-Protein
Phase II Study of Florbetaben (BAY 94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid in Patients With Probable Alzheimer's Disease Compared to Healthy Volunteers
The aim of this study is to evaluate the efficacy, safety of a single dose of BAY 94-9172 (ZK 6013443) as an investigational medicinal product (IMP) in detecting cerebral protein-plaque (amyloid beta) with positron emission…
- Trial name
- NCT00750282
- Testing
- Florbetaben (BAY94-9172)
- Where
- 23 sites in United States, Australia and 3 more
- Volunteers
- 422 people
- Sponsor
- Lantheus Biosciences Ltd.
Parkinson Disease
Initial Investigation of [18F]P17-059 in Parkinson's Disease Patients and Healthy Volunteers
This study investigates the initial safety profile of [18F]P17-059 in healthy volunteers including dosimetry determination, and compares regional brain uptake and kinetics of [18F]P17-059 in Parkinson's disease patients with…
- Trial name
- NCT03903549
- Testing
- [18F]P17-059
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Five Eleven Pharma, Inc.
Malignant Neoplasm
Multi-Tracer Positron Emission Tomography in Patients With Solid Tumors
This clinical trial studies multi-tracer positron emission tomography in patients with solid tumors. Diagnostic procedures, such as multi-tracer positron emission tomography, may help measure a patient's response to treatment.
- Trial name
- NCT01243333
- Testing
- [F-18]fluorodeoxyglucose, [F-18]fluorothymidine, Positron Emission Tomography
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Utah
Breast Cancer, Lobular Breast Carcinoma
A Study Comparing Cancer Imaging Approaches in People With Lobular Breast Cancer
The purpose of this study to compare two types of cancer imaging scans to see which is better at detecting and monitoring metastatic ILC.
- Conditions
- Breast Cancer, Lobular Breast Carcinoma, Breast Carcinoma, Metastatic Breast Cancer
- Trial name
- NCT06557148
- Testing
- 18F-Fluoroestradiol PET/CT
- Where
- 7 sites in United States
- Volunteers
- 7 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Metastatic Solid Tumor
LAG3 PET Imaging in Advanced Solid Tumors
This is an investigator-initiated, single-center, open-label clinical trial designed to evaluate the safety and PK of the PET tracer 89Zr-DFO-REGN3767 in patients prior to and during treatment.
- Trial name
- NCT04706715
- Testing
- 89Zr-DFO-REGN3767, Cemiplimab
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- University Medical Center Groningen
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