Clinical trials: Post COVID Condition
Long COVID
Research of the Long-COVID-19 Syndrome in the Children
During the pandemic of the new coronavirus infection COVID-19 in the world community, in the Russian Federation, in particular in the Samara region throughout the pandemic period from the end of 2019, when the first outbreak of a…
- Trial name
- NCT05817006
- Testing
- Device
- Where
- Russia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Samara State Medical University
Covid19, Follow up
Post ICU Follow up in Patients With Severe SARS-CoV-2 Infection (Covid-19)
Patients affected by new coronavirus infectious disease (COVID) were mostly hospitalized in ICU. This infection seems to cause widespread organ injury (i.e acute renal injury, neurological disorders, pulmonary embolism,…).
- Conditions
- Covid19, Follow up, Rehabilitation
- Trial name
- NCT04491214
- Testing
- quality of live assessment
- Where
- France
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Contact Person From COVID-19 Confirmed Patient
Hydroxychloroquine as Post Exposure Prophylaxis for SARS-CoV-2(HOPE Trial)
There is no known definite treatment after exposure to SARS-CoV-2, but the some animal and clinical trials confirmed the efficacy of hydroxychloroquine (HCQ) or chloroquine against SARS-CoV-2.
- Trial name
- COVID-19 (NCT04330144)
- Testing
- Hydroxychloroquine as post exposure prophylaxis, Others(No intervention)
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
SARS-CoV-2 Infection
Understanding the Long-term Impact of COVID on Children and Families
This is a combined retrospective and prospective, longitudinal, observational meta-cohort of individuals age 0-25 years who will enter the cohort with and without SARS-CoV-2 infection at varying stages before and after infection.
- Trial name
- NCT05172011
- Where
- 65 sites in United States
- Volunteers
- 15,028 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
COVID-19, Long COVID
CORona (COVID-19) Follow Up Study: Epidemiology, Pathophysiology, Prediction, and Communication
The CORFU study, funded by ZonMW, is a prospective, multiple, cohort study with a maximum follow-up of 24 months after COVID-19.
- Conditions
- COVID-19, Long COVID, Post COVID-19 Condition
- Trial name
- CORFU (NCT05240742)
- Testing
- no intervention, the CORFU study conducts analyses based on data which has been prospectively collected (and aggregated when possible) in 7 existing cohorts
- Where
- Netherlands
- Volunteers
- 4,291 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
SARS-CoV-2, Post-acute COVID-19 Syndrome
Neurological Outcome After SARS-CoV-2 Infection
Wider research context: Since the recognition of SARS-CoV-2 outbreak in 2019, there are now over 126 million COVID-19 cases worldwide with more than 2.7 million deaths.
- Trial name
- ATTRACT (NCT05025839)
- Testing
- No Intervention
- Where
- Austria
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
SARS-CoV-2 Infection
VLA2001 Booster in Adult Participants After Priming With mRNA COVID-19 Vaccine and/or Natural SARS-CoV-2 Infection
This is a clinical study to investigate the safety, tolerability and immunogenicity of a VLA2001 booster vaccination in participants aged 18 years and older. In total approximately 275 participants are planned to be enrolled.
- Trial name
- NCT05364242
- Testing
- VLA2001
- Where
- 4 sites in Netherlands, New Zealand
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Valneva Austria GmbH
Anosmia, Asymptomatic COVID-19
Longitudinal At Home Smell Testing to Detect Infection by SARS-CoV-2
The purpose of this study is to learn more about how to better track smell recovery in people who have been infected with the SARS-CoV-2 virus (which causes COVID-19).
- Conditions
- Anosmia, Asymptomatic COVID-19, COVID-19 Respiratory Infection, Influenza
- Trial name
- NCT05040659
- Testing
- AROMHA Longitudinal Smell Test
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Covid19, MIS-C Associated With COVID-19
Pediatric COVID Outcomes Study (PECOS)
This is a multisite prospective observational study to evaluate the clinical sequelae of symptomatic and asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the pediatric population, including…
- Conditions
- Covid19, MIS-C Associated With COVID-19, MIS-C Multisystem Inflammatory Syndrome in Children, SARS-CoV2 Infection
- Trial name
- NCT04830852
- Where
- 2 sites in United States
- Volunteers
- 1,097 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
COVID-19 Pneumonia, Post-acute COVID-19 Syndrome
Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19
Investigation of the correlation of CT-morphological changes of the lung compared to regional ventilation distribution on electrical impedance tomography in patients with post-acute-Covid-19 symptoms.
- Conditions
- COVID-19 Pneumonia, Post-acute COVID-19 Syndrome, Electric Impedance
- Trial name
- NCT05238623
- Testing
- additional EIT Measurement
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jan-Christoph Lewejohann
COVID-19
Fascial Tissue Response to Manual Therapy: Implications in Long COVID-19
According to the World Health Organization (WHO), as of mid-September 2022, more than 21 million Brazilians have recovered from COVID-19.
- Trial name
- NCT06348186
- Testing
- Guidebook, Guidebook and Myofascial Reorganization® (RMF).
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the State of Santa Catarina
PASC Post Acute Sequelae of COVID-19
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
This study uses total-body [¹⁸F]F-AraG PET/CT imaging to investigate immune activation and vascular changes in individuals with post-acute sequelae of SARS-CoV-2 infection (PASC), also known as Long COVID.
- Trial name
- NCT07076862
- Testing
- A.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), A.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only), B.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static)
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
COVID-19, Corona Virus Infection
Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP)
This is a clinical study for the prevention of SARS-CoV-2 infection in adults exposed to the virus. This study will enroll up to 2000 asymptomatic men and women 18 to 80 years of age (inclusive) who are close contacts of persons…
- Conditions
- COVID-19, Corona Virus Infection, SARS (Severe Acute Respiratory Syndrome), SARS-CoV-2
- Trial name
- NCT04328961
- Testing
- Hydroxychloroquine Sulfate, Ascorbic Acid
- Where
- 8 sites in United States
- Volunteers
- 943 people, healthy volunteers welcome
- Sponsor
- University of Washington
Long COVID-19 Syndrome, Long COVID Symptoms
Epigenetic Changes in Long COVID Patients
The goal of this observational study is to improve the understanding of the biological mechanisms underlying long COVID and to identify molecular biomarkers that may support its diagnosis, prognosis, and future precision medicine…
- Trial name
- ECLIPSE (NCT07757620)
- Where
- 3 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
SARS CoV-2, Developmental Disorder
Neurological Development In Toddlers After Maternal SARS-CoV-2 Infection During Pregnancy
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is a virus that causes neurological symptoms in a significant proportion of patients in addition to respiratory symptoms.
- Conditions
- SARS CoV-2, Developmental Disorder, Pregnancy Related
- Trial name
- CRONOS-Kids (NCT06968897)
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Long COVID-19
Antibodies and Immunity After Vaccination of Recovered Patients With COVID-19 and Long COVID-19 Symptoms
We investigated the association between immune system responsibilities in Long COVID patients and Full recovery patients.
- Trial name
- NCT05484700
- Where
- Thailand
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Mahidol University
ME/CFS, Long COVID
Is Swimming a More Tolerable Form of Movement for Individuals With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome?
Individuals with ME/CFS experience profound exercise intolerance and post-exertional malaise. This remote (app-based) pilot study explores whether light, fully self-paced, swimming may be a tolerable form of movement for people…
- Conditions
- ME/CFS, Long COVID, Post- COVID-19 Syndrome, POTS - Postural Orthostatic Tachycardia Syndrome
- Trial name
- ME/CFS (NCT07454395)
- Testing
- Swimming, Cycling
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Post-acute COVID-19 Syndromes
The Roles of Vitamin D and Microbiome in Children With Post-acute COVID-19 Syndromes (PACS) and Long COVID
A double-blind study to evaluate the role of human microbiome and vitamin D in the development of long COVID and PACS in children.
- Trial name
- NCT05633472
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Long COVID, POTS - Postural Orthostatic Tachycardia Syndrome
Long COVID Immune Profiling
Parasympathetic nervous system (PNS) is part of the body's autonomic nervous system(PNS) protects body against inflammation. Study shows that reduced PNS function activity is associated with persistent inflammation.
- Conditions
- Long COVID, POTS - Postural Orthostatic Tachycardia Syndrome, Autonomic Dysfunction
- Trial name
- NCT06027255
- Testing
- IL-6, cytokines (IL-17, and IFN-ɣ), Compass 31
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
COVID-19, Long Haul
Digital Cognition Study During Long-COVID
The persistence of the COVID-19 disease symptoms, such as extreme fatigue, shortness of breath, cardiovascular complications, depression and anxiety, pain, brain fog, loss of taste/smell, headaches as well as loss of memory has…
- Trial name
- DIGICOG (NCT06391970)
- Testing
- Cognitive screening
- Where
- Luxembourg
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health