Clinical trials: Post Cerebral Hemorrhage
Hemorrhage, Premature Infants
NIRS Monitoring in Premature Infants
This study uses frequency domain near-infrared spectroscopy coupled with diffuse correlation spectroscopy (FDNIRS-DCS) technology for monitoring cerebral blood flow (CBF) and cerebral oxygen metabolism (CMRO2) at the bedside for…
- Conditions
- Hemorrhage, Premature Infants, Newborn, Hydrocephalus
- Trial name
- NCT02601339
- Testing
- ETV/CPC
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Spontaneous Intracerebral Hemorrhage
Early-Start Antiplatelet Treatment After Neurosurgery in Patients With Spontaneous Intracerebral Hemorrhage
This study is a multicenter, prospective, open-label, endpoint-blind, randomized controlled study.Patients receiving surgical treatment for SICH were divided into groups using the random machine method.
- Trial name
- NCT04820972
- Testing
- Antiplatelet Agents
- Where
- China
- Volunteers
- 269 people
- Sponsor
- Beijing Tiantan Hospital
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Aneurysmal Subarachnoid Hemorrhage
Clazosentan in Preventing the Occurrence of Cerebral Vasospasm Following an Aneurysmal Subarachnoid Hemorrhage (aSAH)
The purpose of the study is to measure how effective and safe three different doses of the drug clazosentan are in preventing vasospasm after subarachnoid hemorrhage.
- Trial name
- CONSCIOUS-1 (NCT00111085)
- Testing
- Clazosentan 1 mg/h, Clazosentan 5 mg/h, Clazosentan 15 mg/h
- Where
- 16 sites in United States, Canada
- Volunteers
- 413 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Stroke, Acute
Establishment and Validation of a Predictive Model for Hemorrhage
Background: Patients with acute ischemic stroke (AIS) are at risk of hemorrhagic transformation (HT) after intravenous thrombolysis.
- Trial name
- NCT04745052
- Testing
- Clinical observation index
- Where
- 2 sites in China
- Volunteers
- 240 people
- Sponsor
- Shenzhen Second People's Hospital
Subarachnoid Hemorrhage
Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm
The purpose of the study is to examine the safety of a 14 day infusion of sodium nitrite, and to study the pharmacokinetics of nitrite, during a 14 day infusion in patients with ruptured cerebral aneurysms.
- Trial name
- NCT00873015
- Testing
- Sodium nitrite, Saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Hope Pharmaceuticals
Intracerebral Hemorrhage, Hemorrhagic Stroke
Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage
Spontaneous intracerebral haemorrhage (ICH) is a severe form of stroke with high mortality and frequent long-term disability. Current tools to predict how an individual patient will recover are limited.
- Trial name
- CR-4-Health (NCT07882784)
- Where
- 3 sites in Austria, Slovenia
- Volunteers
- 300 people
- Sponsor
- University Medical Centre Maribor
Intracerebral Hemorrhage, Obstructive Hydrocephalus
A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular Hemorrhage
The purpose of this study is to determine if usage of early lumbar drainage leads to less shunt surgery and less catheter associated complications in patients with communicating hydrocephalus after intracerebral hemorrhage with…
- Trial name
- LUCAS-IVH (NCT01041950)
- Testing
- Lumbar drainage
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Intracerebral Hemorrhage, Nontraumatic Intracerebral Hemorrhage
CIRP and Cathepsin B in Neuroinflammation After Intracerebral Hemorrhage
This is a single-center, investigator-initiated, prospective observational case-control study. Patients with intracerebral hemorrhage and healthy controls will be enrolled at Xuanwu Hospital, Capital Medical University.
- Trial name
- CIRP-ICH (NCT07665255)
- Testing
- Blood Sample Collection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Subarachnoid Hemorrhage, Aneurysmal, Intracerebral Hemorrhage (ICH)
Non-invasive Measuring of Cerebral Perfusion After Severe Brain Injury With Near-infrared-spectroscopy and ICG
The purpose of this study is to show if it is possible to detect secondary ischemic events in patients with severe brain injury or cerebral haemorrhage with the help of non-invasive near-infrared spectroscopy (NIRS) by using the…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Intracerebral Hemorrhage (ICH), Traumatic Brain Injury
- Trial name
- NCT01836848
- Testing
- measuring cerebral perfusion by NIRS with ICG
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Cologne
Aneurysmal Subarachnoid Hemorrhage, Familial
Non Invasive Measurements of Intracranial Pressure After Aneurysmal Subarachnoid Hemorrhage
In patients at risk of increased intracranial pressure (ICP), ICP measurements require invasive transducers, usually with insertion of a catheter into the cranium, or through a spinal tap.
- Trial name
- HEMAPIC (NCT03040284)
- Testing
- Echodia® hand-held equipment (ELIOS)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Subarachnoid Hemorrhage, Aneurysmal
Evaluation of Neuroinflamation of SAH
The investigators are planning that can these markers be used a predictive marker at SAH and for this aim we will study both patiens' blood sample and their CT image.
- Trial name
- BAP (NCT03822260)
- Testing
- Bezmialem VAkif Unv. Ethical board
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Acute Ischemic Stroke, Endovascular Thrombectomy
The Prediction of Hemorrhage Transformation by Cerebral Autoregulation in AIS Patient After Endovascular Thrombectomy
This observational study was designed for observe the cerebral hemodynamics and dynamic cerebral autoregulation (dCA) after endovascular thrombectomy (EVT) in acute ischemic stroke (AIS) patients.
- Conditions
- Acute Ischemic Stroke, Endovascular Thrombectomy, Dynamic Cerebral Autoregulation
- Trial name
- PHASE (NCT06361017)
- Testing
- endovascular thrombectomy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xuanwu Hospital, Beijing
Aneurysmal Subarachnoid Hemorrhage
Ultrasound Perfusion Imaging After Aneurysmal Subarachnoid Hemorrhage
The purpose of this study is to examine wether delayed cerebral ischemia can be predicted by ultrasound brain perfusion imaging in patients with aneurysmal subarachnoid hemorrhage (SAH).
- Trial name
- PSAB (NCT01537263)
- Testing
- Ultrasound Perfusion Imaging
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Asklepios Kliniken Hamburg GmbH
Subarachnoid Haemorrhage (SAH)
ALI & Pulmonary HA Deposition After SAH
Acute lung injury is a common complication of subarachnoid hematoma (SAH), and a significant risk factor for death in patients with SAH.
- Trial name
- NCT06628531
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Tianjin Medical University
Brain Ischemia, Intracranial Haemorrhage
Usability of Andago V2.0 in Gait Rehabilitation of Stroke Patients
Andago V2.0 is a recently developed overground gait and balance training device. Many patients in neurorehabilitation suffer from gait disorders, most typically after stroke.
- Trial name
- NCT02735460
- Testing
- Andago V2.0
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Rehaklinik Zihlschlacht AG
Aneurysmal Subarachnoid Haemorrhage, SAH
Goal Directed Therapy After Aneurysmal Subarachnoid Haemorrhage
The objective of this study is to determine whether a goal-directed therapy can reduce the incidence of delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage.
- Trial name
- PiSAH (NCT01832389)
- Testing
- PiCCO
- Where
- Germany
- Volunteers
- 108 people
- Sponsor
- Technical University of Munich
Cerebral Hemorrhage, Hypothermia
Targeted Temperature Management After Intracerebral Hemorrhage
Early hematoma growth (HG) after spontaneous intra-cerebral/intra-parenchymal hemorrhage (IPH) is common and associated with neurological deterioration and poor clinical outcome.
- Trial name
- NCT01866384
- Testing
- mild induced hypothermia, Normal Temperature
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Thomas Jefferson University
Endocrine Dysfunction, Cerebral Infarctions
Endocrine Dysfunction and Quality of Life After Subarachnoid Hemorrhage
Investigation of the incidence of endocrine dysfunction following subarachnoid hemorrhage (SAH), and to see if this has a relation to CNS lesions as evaluated by MRI and to common symptoms after SAH such as general exhaustion…
- Conditions
- Endocrine Dysfunction, Cerebral Infarctions, Quality of Life
- Trial name
- NCT01101711
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Lund University Hospital
Atrial Fibrillation, Stroke
Peri-device Leakage Closure After LAAO
The investigators thought to evaluate the safety and feasibility of peri-device leakage closure after left atrial appendage occlusion (LAAO, either surgical or interventional) with different devices.
- Conditions
- Atrial Fibrillation, Stroke, Bleeding, Leakage of Cardiac Device
- Trial name
- NCT04590898
- Testing
- Peri-device leakage closure after left atrial appendage occlusion
- Where
- 16 sites in United States, Denmark and 5 more
- Volunteers
- 85 people
- Sponsor
- Cardiovascular Center Frankfurt