Clinical trials: Post Herpetic Neuralgia (PHN)
Osteoarthritis, Pain
A SAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers
A First-in-Human, Double-blind, Randomized, Placebo-controlled, Single Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of iN1011-N17 after Oral Administration in Healthy Volunteers.
- Conditions
- Osteoarthritis, Pain, Post Herpetic Neuralgia, Neuropathic Pain
- Trial name
- NCT05496205
- Testing
- iN1011-N17
- Where
- Australia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- iN Therapeutics Co., Ltd.
Postherpetic Neuralgia
Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjects
This is a single-center, randomized, single-dose, active-controlled study in healthy male and female subjects. The study will enroll subjects to evaluate the PK of 3 dose strengths (50 mg, 100 mg and 200 mg) of GTX-101 compared…
- Trial name
- NCT05517486
- Testing
- GTX-101, Bupivacaine HCl subcutaneous injection
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Grace Therapeutics Inc.
Post-herpetic Neuralgia
Dose Response Study of EMA401 in Patients With Post-herpetic Neuralgia (PHN)
This study was designed to characterize dose response, and evaluate safety and efficacy of three different doses of EMA401 compared to placebo in patients with post-herpetic neuralgia (PHN).
- Trial name
- EMPHENE (NCT03094195)
- Testing
- EMA401
- Where
- 58 sites in Australia, Austria and 17 more
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Pain, Complex Regional Pain Syndromes
The Success of Lumbar Sympathetic Ganglion Block Using Lower Extremity Perfusion Index
The patient, who is experiencing chronic pain in the lower extremities persisting for more than three months, is scheduled to undergo lumbar sympathetic ganglion block.
- Conditions
- Chronic Pain, Complex Regional Pain Syndromes, Peripheral Neuropathy, Post Herpetic Neuralgia
- Trial name
- NCT06241820
- Testing
- Lumbar Sympathetic Ganglion Block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jeongsoo Kim
Herpes Zoster
A Study to Assess the Burden of Herpes Zoster and Postherpetic Neuralgia in Japanese Adults Aged Sixty Years and Above
The study aims to estimate the incidence of herpes zoster (HZ), proportion of postherpetic neuralgia (PHN) and the economic burden and impact on quality of life, in Japanese adults greater than or equal to sixty years of age.
- Trial name
- NCT01873365
- Testing
- Data collection
- Where
- 14 sites in Japan
- Volunteers
- 448 people
- Sponsor
- GlaxoSmithKline
Neuralgia, Postherpetic
Dose Ranging Trial to Determine the Safety and Efficacy of EMA401 in Patients With PHN
The study is a randomized, double blind, placebo-controlled, parallel-group comparison (two dose levels of EMA401 versus a placebo group), of safety and efficacy in patients with postherpetic neuralgia.
- Trial name
- NCT02426411
- Testing
- EMA401 200 mg, EMA401 600 mg
- Sponsor
- Spinifex Pharmaceuticals Pty Ltd
PHN - Post-Herpetic Neuritis
A Phase IIb/III Clinical Study to Evaluate the Efficacy and Safety of APC101 in Patients With Postherpetic Neuralgia.
APC101 is developed to provide continuous lidocaine administration over 24 hours and is safe when administered to intact skin. Dispensing from a metered-dose spray pump, APC101 provides once or twice daily flexible dosing options…
- Trial name
- PHN (NCT07599800)
- Testing
- APC101, Control
- Where
- 2 sites in United States, Australia
- Volunteers
- 333 people
- Sponsor
- Andros Pharmaceuticals Co., Ltd.
Neuralgia, Postherpetic
Efficacy, Safety and Tolerability Study of TAK-583 in Subjects With Postherpetic Neuralgia
The purpose of this study is to evaluate the efficacy of TAK-583, once daily (QD), in relieving pain in subjects with postherpetic neuralgia.
- Trial name
- NCT00377598
- Testing
- TAK-583
- Where
- 48 sites in Australia, Bulgaria and 7 more
- Volunteers
- 399 people
- Sponsor
- Takeda
Herpes Zoster
Herpes Zoster: Risk Factors, Complications and Special Situations
This retrospective analysis is to investigate patients' history and clinical presentation in Herpes Zoster (HZ), Zoster-related complications, post-Zoster neuralgia and Herpes Zoster management in order to improve the management…
- Trial name
- NCT03903237
- Testing
- retrospective chart review
- Where
- Switzerland
- Volunteers
- 355 people
- Sponsor
- University Hospital, Basel, Switzerland
Herpes Zoster, Shingles
ZOSTAVAX™ (Zoster Vaccine Live) Long-term Effectiveness Study (V211-024)
This study will describe the impact of vaccination with ZOSTAVAX™ on the epidemiology of herpes zoster (HZ) in a cohort of vaccinated participants 50 years or age or older, compared to a cohort of unvaccinated participants.
- Trial name
- NCT01600079
- Testing
- ZOSTAVAX™
- Volunteers
- 1,505,647 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Postherpetic Neuralgia, Shingles
A 2 Week Study of Topical KD7040 in the Treatment of Postherpetic Neuralgia (PHN)
This study will evaluate the safety and efficacy of 2 weeks of topical KD7040 versus placebo in the treatment of postherpetic neuralgia.
- Conditions
- Postherpetic Neuralgia, Shingles, Herpes Zoster, Neuropathic Pain
- Trial name
- NCT00576108
- Testing
- KD7040 Topical Gel
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Kalypsys, Inc.
Neuropathic Pain, Diabetic Peripheral Neuropathy (DPN)
Oral LAT8881 in Neuropathic Pain
This is a randomised, placebo-controlled, double-blind, crossover, phase IIa study to investigate the efficacy and safety of oral LAT8881 in neuropathic pain.
- Conditions
- Neuropathic Pain, Diabetic Peripheral Neuropathy (DPN), Post Herpetic Neuralgia (PHN)
- Trial name
- NCT03865953
- Testing
- LAT8881
- Where
- 6 sites in Australia, United Kingdom
- Volunteers
- 53 people
- Sponsor
- Lateral Pharma Pty Ltd
Healthy
Bioequivalence Study of Two Formulations of Pregabalin CR (Controlled-release) Table 150 mg
The purpose of this clinical trial is to (1) evaluate the bioequivalence(BE) of GLA5PR GLARS-NF3 tablet 150mg administered regular diet relative to GLA5PR GLARS-NF1 tablet 150mg administered regular diet and (2) determine the…
- Trial name
- NCT02955472
- Testing
- GLA5PR GLARS-NF3 tablet 150mg, GLA5PR GLARS-NF1 tablet 150mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Herpes Zoster Pain
Efficacy and Safety of Intravenous Dexamethasone Palmitate Treatments in Acute and Subacute Herpes Zoster Pain
This is a randomized, prospective, multicenter, open-label, blinded-endpoint study investigating the efficacy and safety of dexamethasone palmitate (DXP) for treating acute and subacute herpes zoster (shingles) pain.
- Trial name
- NCT07344246
- Testing
- intravenous infusion with 4 mg dexamethasone palmitate or 8 mg dexamethasone palmitate
- Where
- China
- Volunteers
- 954 people
- Sponsor
- Beijing Tiantan Hospital
Non-diabetic Painful Peripheral Polyneuropathy, Postherpetic Neuralgia (PHN)
A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment
This study is comparing the efficacy and tolerability of Qutenza with that of pregabalin in patients suffering from peripheral neuropathic pain.
- Conditions
- Non-diabetic Painful Peripheral Polyneuropathy, Postherpetic Neuralgia (PHN), Peripheral Nerve Injury (PNI)
- Trial name
- ELEVATE (NCT01713426)
- Testing
- Qutenza, Pregabalin
- Where
- 98 sites in Armenia, Austria and 20 more
- Volunteers
- 568 people
- Sponsor
- Astellas Pharma Europe Ltd.
Chronic Pain, Trigeminal Neuralgia
Regional-anaesthesiological Infiltration Techniques for the Management of Chronic Pain: a Retrospective Study
There is a significant debate whether local infiltration techniques may be a method to treat complicated chronic pain syndromes, e.g. refractory headache.
- Conditions
- Chronic Pain, Trigeminal Neuralgia, Cluster Headache, Post-Zoster Neuralgia
- Trial name
- RetroBlock (NCT03066037)
- Testing
- regional-anaesthesiological infiltration
- Where
- Germany
- Volunteers
- 83 people
- Sponsor
- Charite University, Berlin, Germany
Postherpetic Neuralgia, Neuralgia
Evaluation of the Efficacy, Tolerability and Safety of Etoricoxib (Arcoxia) in Patients With Neuropathic Pain
The present study will aim to determine the safety, efficacy, and tolerability of etoricoxib, an NSAID pain reliever, in patients with Neuropathic pain.
- Trial name
- NCT01264237
- Testing
- Etoricoxib
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Analgesic Solutions
Healthy
Bioequivalence Study of Two Formulations of Pregabalin CR(Controlled-release) Table 300 mg
The purpose of this clinical trial is to (1) evaluate the bioequivalence(BE) of GLA5PR GLARS-NF3 tablet 300mg administered regular diet relative to GLA5PR GLARS-NF1 tablet 300mg administered regular diet and (2) determine the…
- Trial name
- NCT02952937
- Testing
- GLA5PR GLARS-NF3 tablet 300mg, GLA5PR GLARS-NF1 tablet 300mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Complex Regional Pain Syndromes, Postherpetic Neuralgia
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block
The purpose of this study is to investigate the effect of ultrasound-guided thoracic paravertebral block (TPVB) when performing sympathetic block for upper limb pain control.
- Conditions
- Complex Regional Pain Syndromes, Postherpetic Neuralgia, Phantom Limb Pain, Chronic Post Surgical Pain
- Trial name
- NCT04876989
- Testing
- US-SGB, US-TPVB
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University
Zoster Without Complications
Regional Anesthesia to Relief Zoster Pain
Pain in Herpes is a serious issue for patients. at the acute phase it is a moderate to severe pain . 30% patients will develop a post herpetic neuralgia this percentage up to 70 % after 60 years old.
- Trial name
- NCT04133142
- Testing
- peripheral nerve block, inter fascial nerve block
- Where
- Vietnam
- Sponsor
- Vinmec Healthcare System