Clinical trials: Post ICU Syndrome
Acute Respiratory Distress Syndrome (ARDS), Post Intensive Care Syndrome (PICS)
An Observational Study to Identify New Health Problems Arising After an Intensive Care Unit Admission in People With Acute Respiratory Distress Syndrome in the United States
This is an observational study in which data already collected from people with acute respiratory distress syndrome (ARDS) admitted to an intensive care unit (ICU) are studied.
- Trial name
- SeeMe Tool (NCT06272942)
- Testing
- An ICU admission and a temporally related ARDS diagnosis
- Where
- United States
- Volunteers
- 640,058 people
- Sponsor
- Bayer
Post-Intensive Care Syndrome, Sedation
A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol
This pooled analysis will assess Cognitive, Mental Health, Functioning, and Quality of Life Assessments data from the Phase 3 registration studies INSPiRE-ICU 1 (NCT05312385) and INSPiRE-ICU 2 (NCT05327296) to explore potential…
- Trial name
- NCT06809218
- Testing
- Inhaled isoflurane administered by Sedaconda ACD-S, Intravenous infusion of propofol
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Sedana Medical
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Post ICU Syndrome
CoV-PICS: A Virtual Post-ICU Clinic
This is a pilot study to evaluate the feasibility of a COVID-19 virtual Post Intensive Care Syndrome (PICS) clinic (CoV-PICS). The findings from this study are the first steps in determining the feasibility and potential impact…
- Trial name
- NCT04490278
- Testing
- Medical Record Review - Inpatient Treatment, Online Questionnaires
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Post Intensive Care Syndrome
Multi-sensory Intervention Room Application (MIRA) Device in the NSICU
The purpose of this research study is to determine the safety, feasibility, and efficacy of a device, MIRA, on the physical, mental, and cognitive health of Neurosciences Intensive Care Unit (NSICU) patients.
- Trial name
- NCT06509815
- Testing
- MIRA
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Child, Intensive Care Unit Acquired Weakness
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
While mortality in U.S. pediatric intensive care units (PICUs) is improving, surviving children frequently develop persistent physical, cognitive, and psychological impairments.
- Conditions
- Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
- Trial name
- PICU Up! (NCT04989790)
- Testing
- PICU Up!
- Where
- 11 sites in United States
- Volunteers
- 1,470 people
- Sponsor
- Johns Hopkins University
Health-related Quality of Life
Health-related Quality of Life and Functional Impairments After Intensive Care Unit Discharge
Diagnostic and therapeutic progress of the last twenty years has been accompanied by an evolution in the morbidity and mortality of intensive care unit (ICU) patients.
- Trial name
- CritiQoL2 (NCT05111522)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Versailles Hospital
Postintensive Care Syndrome, Family Members
Family Support Intervention in Intensive Care Units
Background: Family members of critically ill patients face considerable uncertainty and distress during their close other's intensive care unit (ICU) stay, with about 20-60% of family members experiencing post-traumatic distress…
- Conditions
- Postintensive Care Syndrome, Family Members, Quality of Life, Depression, Anxiety
- Trial name
- FICUS (NCT05280691)
- Testing
- Family Support Intervention (FSI)
- Where
- 12 sites in Switzerland
- Volunteers
- 885 people
- Sponsor
- Rahel Naef
Intensive Care Unit Delirium, Covid19
Delirium in Covid-19: Germany-wide Covid-19 Intensive Register
The global pandemic caused by the SARS-CoV-2 virus is confronting the German health system with a novel pathogen. This means that a timely evaluation of all available results is required.
- Conditions
- Intensive Care Unit Delirium, Covid19, Post Intensive Care Unit Syndrome
- Trial name
- NCT04775017
- Where
- Germany
- Volunteers
- 2,398 people
- Sponsor
- Charite University, Berlin, Germany
Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy
Comparison of Central Venous Oxygen Saturation Measurements by Non-invasive Mespere Venous Oximeter and Central Venous Catheter
The intent of this study is to validate the venous blood oxygenation measurements of the Mespere VA Oximeter compared to the saturations measured by venous blood sampling through an inserted central vein catheter, which is…
- Conditions
- Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy, Cardiogenic Shock Post Myocardial Infarction, Hypoxemic Respiratory Failure.
- Trial name
- NCT01788956
- Testing
- Mespere Venous Oximeter, Co-Oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mespere Lifesciences Inc.
Post Intensive Care Syndrome
Prevalence and Risk Factor of Post-intensive Care Syndrome in Neuro-ICU
Post-intensive care syndrome (PICS) is the set of disabling symptoms that can appear or worsen following a stay in intensive care. These symptoms are physical, cognitive, or psychiatric.
- Trial name
- STRESSréa (NCT06308835)
- Testing
- questionnaires
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Failure and Chronic Kidney Disease Post-ICU
Dapagliflozin for Cardio-renal Protection After ICU Discharge
Several millions of patients are admitted to ICUs in Europe or USA each year. We and others, have shown that patients discharged from intensive care units (ICU) have a high incidence of cardiovascular and/or renal events and high…
- Trial name
- DAPA-ICU (NCT07025629)
- Testing
- Dapagliflozin 10 MG Oral Tablet [Farxiga]
- Where
- 2 sites in France
- Volunteers
- 600 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Physical Functional Impairment, Cognitive Impairment
PICS-p Longitudinal Cohort Study
Children who survive critical illness may develop new or worsening problems with physical health, cognitive status, emotional well-being, and social functioning.
- Conditions
- Physical Functional Impairment, Cognitive Impairment, Psychological Distress, Impaired Social Functioning
- Trial name
- PICSpLCS (NCT07876271)
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Fudan University
Post Intensive Care Syndrome
Post-Resuscitation Interdisciplinary Consultation System: a Randomized, Multicenter, Interventional Study to Assess Quality of Life After a Stay in the COPRéa Intensive Care Unit
A patient's stay in the ICU is not without consequences and can cause various physical and/or psychological sequelae such as anxiety, depression, post-traumatic stress disorder (PTSD), physical weakness and memory problems.
- Trial name
- COPRéa (NCT05625867)
- Testing
- Psychological and quality of life questionnaires, Interdisciplinary consultation at 4/5 months
- Where
- France
- Volunteers
- 404 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
PTSD, Post ICU Syndrome
Intensive Care Unit (ICU) Diary Project
Psychological morbidity in both patients and family members related to the intensive care unit (ICU) experience is an often overlooked, and potentially persistent, healthcare problem recognized by the Society of Critical Care…
- Trial name
- NCT04305353
- Testing
- Diary (blank journal) plus PTSD psycho-education, PTSD psycho-education alone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tulane University School of Medicine
Post Intensive Care Syndrome (PICS), Critical Illness
"PROTECT-ICU: Impact of an Educational Intervention
Brief Summary The goal of this study is to learn if a structured training program for intensive care unit (ICU) staff can reduce health problems after a stay in the ICU in adults.
- Trial name
- PROTECT-ICU (NCT07542613)
- Testing
- Standardized Training on the ABCDEF Care Bundle (A-F), Standardized training on the expanded ABCDEF care bundle (A-Z)
- Where
- 2 sites in Spain
- Volunteers
- 900 people
- Sponsor
- Carola Giménez-Esparza Vich
Post Intensive Care Unit Syndrome, Intensive Care Unit Acquired Weakness
Intensive Care Unit Recovery
Survival rates of patients with critical illness have increased due to improved facilities and treatment methods in the intensive care unit (ICU).
- Conditions
- Post Intensive Care Unit Syndrome, Intensive Care Unit Acquired Weakness, Critical Illness
- Trial name
- ICU-RE (NCT04154995)
- Testing
- Venipuncture, Ultrasound Quadriceps Muscles
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- Frisius Medisch Centrum
Frailty, Delirium Confusional State
Patients With Long-stay at ICU: Factors and Evaluation - Feasibility Study
Every year, many critically ill patients are admitted to an intensive care unit (ICU). Most stay only a few days, but a smaller group stays much longer.
- Conditions
- Frailty, Delirium Confusional State, Persistent Critical Illness, Post-Intensive Care Syndrome
- Trial name
- LIFE-ICU (NCT07851974)
- Where
- 4 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Uppsala University
Chronic Pain, Post ICU Syndrome
Persistent Pain and Its Impact on Quality of Life COVID-19 Patients That Required Critical Care
COVID-19 infection produces thousands of hospital admissions in a very short period of time, including critical care patients. It is expected that those who survive a severe spectrum of the disease, will present some degree of…
- Conditions
- Chronic Pain, Post ICU Syndrome, Quality of Life
- Trial name
- NCT04887220
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
COVID-19, ARDS (Acute Respiratory Distress Syndrome)
Long-Term Outcomes After ICU-Treated COVID-19 ARDS
This observational cohort study describes long-term survival and patient-reported health after intensive care unit (ICU) treatment for COVID-19-related acute respiratory distress syndrome (ARDS) in adults treated in a single…
- Trial name
- NCT07397156
- Where
- Poland
- Volunteers
- 283 people
- Sponsor
- University in Zielona Góra