Clinical trials: Post Intensive Care Syndrome
Covid-19, Critical Illness
Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19
Introduction: Survivors of acute respiratory failure develop persistent muscle weakness and deficits in cardiopulmonary endurance combining to limit physical functioning.
- Conditions
- Covid-19, Critical Illness, Post Intensive Care Unit Syndrome, Muscle Weakness
- Trial name
- OPTIMAL (NCT04412330)
- Testing
- ICU Recovery + Physical Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Kentucky
PTSD - Post Traumatic Stress Disorder, Sepsis
The Effect of Early Intervention on the Incidence of Posttraumatic Stress Disorder After Intensive Care Hospitalization Due to Sepsis
In recent years, the survival rate among intensive care patients has improved due to advancements in diagnosing severe infections and the use of broad-spectrum antibiotics.
- Conditions
- PTSD - Post Traumatic Stress Disorder, Sepsis, ICU
- Trial name
- NCT07707765
- Testing
- Psychiatric interview
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Barzilai Medical Center
Post Intensive Care Unit Syndrome, Malnutrition
Micronutrient Levels and Nutritional Status in Critical Illness
Rationale: A significant proportion of patients admitted to the Intensive Care Unit (ICU) is unable to fully recover, even when the initial cause of their illness has been treated.
- Trial name
- NUTRI-ICU (NCT06119711)
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 79 people
- Sponsor
- Frisius Medisch Centrum
Critical Illness, Post Intensive Care Unit Syndrome
Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study
Pediatric Intensive Care Unit (PICU) survival has increased substantially over the past three decades. Currently, an understanding of PICU morbidity and recovery among PICU survivors and their families is limited.
- Trial name
- PICS-p (NCT04967365)
- Where
- 30 sites in United States
- Volunteers
- 755 people
- Sponsor
- University of Pennsylvania
Cardiogenic Shock, Cardiogenic Shock Acute
Prospective Validation of the STOPSHOCK Score - Artificial Intelligence Based Predictive Scoring System to Identify the Risk of Developing Cardiogenic Shock (CS) in Patients Suffering From Acute Coronary Syndrome (ACS)
Cardiogenic shock (CS) is a severe complication of acute coronary syndrome (ACS) with mortality approaching 50% despite the use of percutaneous mechanical circulatory support devices (pMCS).
- Conditions
- Cardiogenic Shock, Cardiogenic Shock Acute, Cardiogenic Shock Post Myocardial Infarction, Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
- Trial name
- STOPSCHOCK (NCT07090382)
- Where
- Slovakia
- Volunteers
- 1,046 people
- Sponsor
- Premedix Academy
Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia
Role of Levothyroxine Supplementation in Delayed Recovery Following Cardiac Surgery
Research indicates that hypothyroidism decreases heart contractility, reduces stroke volume and rate, affects the vascular endothelium, and increases the risk of atherosclerosis, systemic vascular resistance, hypertension…
- Conditions
- Cardiac Surgery Intensive Care Treatment, Delayed Recovery From Anaesthesia, Euthyroid Sick Syndrome, Cardiac Surgery Requiring Cardiopulmonary Bypass
- Trial name
- L-Thyroxine (NCT06660823)
- Testing
- L-thyroxine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Covid19
French Cohort of COVID-19 Patients With Post-intensive Care Syndrome
The purpose of this study is to describe post-intensive care syndrome (PICS) of patients surviving to coronavirus disease 2019 (COVID19) and their rehabilitation and recovery process from hospital to home return
- Trial name
- COREADOM (NCT04590170)
- Testing
- Post-intensive Care unit syndrome, Spatiotemporal measurements of walking
- Where
- 2 sites in France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Delirium in the Intensive Care Unit
Methadone vs. Transdermal Fentanyl for Opioid Withdrawal Syndrome
Many patients in the general intensive care unit experience pain, as a result of an injury or underlying disease, surgery or an invasive procedure.
- Trial name
- NCT05697783
- Testing
- Administration of methadone instead of fentanyl patch
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Post Intensive Care Syndrome, Anxiety
Sensation Awareness Focused Training for Spouses
The purpose of the feasibility study is prevention of Post Intensive Care Syndrome in Family (PICS-F), specifically in spouses of critically ill, mechanically ventilated patients, using a nonpharmacological intervention called…
- Conditions
- Post Intensive Care Syndrome, Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- SAF-T (NCT03129204)
- Testing
- SAF-T
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Post Intensive Care Unit Syndrome, Critical Illness
Improving Recovery After Critical Illness
Rationale: Survival rates of patients with critical illness have increased due to improved facilities and treatment methods in the intensive care unit (ICU).
- Conditions
- Post Intensive Care Unit Syndrome, Critical Illness, Malnutrition, Muscle Weakness
- Trial name
- IMPROVE (NCT05182086)
- Testing
- Group physical therapy and dietary improvements
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Frisius Medisch Centrum
Post Intensive Care Syndrome, Narrative Medicine
Effect of Pediatric Intensive Care Unit Diaries on PICS-p
When children become very sick and need to stay in a Pediatric Intensive Care Unit (PICU), it can have a big impact on their recovery and their family's well-being.
- Conditions
- Post Intensive Care Syndrome, Narrative Medicine, Post Traumatic Stress Disorder, Anxiety
- Trial name
- PICS-p (NCT06310109)
- Testing
- PICU diary
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Bambino Gesù Children's Hospital IRCCS
Icu Delirium, Post Intensive Care Syndrome
ABCDEF Bundle Compliance and ICU Outcomes in Latin America
The goal of this observational study is to evaluate the degree of compliance with the ABCDEF bundle and its relationship with clinical outcomes in adult patients (aged 18 and older) admitted to intensive care units (ICUs) in…
- Conditions
- Icu Delirium, Post Intensive Care Syndrome, Critical Illness
- Trial name
- NCT07783035
- Testing
- ABCDEF Bundle Compliance Assessment
- Volunteers
- 580 people
- Sponsor
- Hospital H+ Queretaro
Frailty, Delirium Confusional State
Patients With Long-stay at ICU: Factors and Evaluation - Feasibility Study
Every year, many critically ill patients are admitted to an intensive care unit (ICU). Most stay only a few days, but a smaller group stays much longer.
- Conditions
- Frailty, Delirium Confusional State, Persistent Critical Illness, Post-Intensive Care Syndrome
- Trial name
- LIFE-ICU (NCT07851974)
- Where
- 4 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Uppsala University
Post-Intensive Care Syndrome
Collaborative Assessment of ICU Recovery Needs
The primary purpose of this study is to better understand the impact of the Society of Critical Care Medicine (SCCM) THRIVE Collaboratives on patients, their families and clinicians.
- Trial name
- CAIRN (NCT03513289)
- Testing
- Patient, Carer, and Clinician Interviews
- Where
- 2 sites in United States, Australia
- Volunteers
- 66 people
- Sponsor
- Vanderbilt University Medical Center
Intensive Care Unit Delirium, Covid19
Delirium in Covid-19: Germany-wide Covid-19 Intensive Register
The global pandemic caused by the SARS-CoV-2 virus is confronting the German health system with a novel pathogen. This means that a timely evaluation of all available results is required.
- Conditions
- Intensive Care Unit Delirium, Covid19, Post Intensive Care Unit Syndrome
- Trial name
- NCT04775017
- Where
- Germany
- Volunteers
- 2,398 people
- Sponsor
- Charite University, Berlin, Germany
COVID-19, Post Intensive Care Syndrome
Aerobic Exercise and Covid-19 Survivors With Post-Intensive Care Syndrome (Pics)
To investigate the effects of aerobic exercise program on physical activity, aerobic capacity, anxiety\& depression in Covid-19 survivors discharged from Intensive Care Unit.
- Trial name
- NCT05341648
- Testing
- Aerobic Exercise Training, Home Plan
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Child, Intensive Care Unit Acquired Weakness
Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children
While mortality in U.S. pediatric intensive care units (PICUs) is improving, surviving children frequently develop persistent physical, cognitive, and psychological impairments.
- Conditions
- Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
- Trial name
- PICU Up! (NCT04989790)
- Testing
- PICU Up!
- Where
- 11 sites in United States
- Volunteers
- 1,470 people
- Sponsor
- Johns Hopkins University
Acute Brain Injury, Cognitive Dysfunction
Cognitive Function and Health-related Quality of Life After Neuro-intensive Care
The study will provide information on cognitive impairment and Health related quality of life in patients surviving 12 months after acute brain injury, generate a hypothesis of useful variables to predict cognitive impairment or…
- Conditions
- Acute Brain Injury, Cognitive Dysfunction, Delirium, Sepsis
- Trial name
- COGNI (NCT04881097)
- Testing
- no intervention
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-Intensive Care Syndrome, Anxiety
Family and Patient Outcomes After Pediatric Intensive Care (FOREVER)
This study aims to evaluate in the Brazilian context, the impact of the implementation of a diary program on patient and family-centered outcomes after PICU discharge.
- Conditions
- Post-Intensive Care Syndrome, Anxiety, Depression, Stress Disorders, Post-Traumatic
- Trial name
- FOREVER (NCT04961697)
- Testing
- Hospital diaries
- Where
- Brazil
- Volunteers
- 431 people
- Sponsor
- D'Or Institute for Research and Education
Post Intensive Care Syndrome, ARDS: Acute Respiratory Distress Syndrome
Combined Activity and Cognitive Intervention for ICU Survivors
This mixed-methods study comprising a 3-arm pilot RCT and a qualitative study aims to investigate the preliminary effects and feasibility of a home-based combined activity and cognitive intervention for ICU survivors…
- Conditions
- Post Intensive Care Syndrome, ARDS: Acute Respiratory Distress Syndrome, Delirium, Loss of Muscle Mass
- Trial name
- NCT06117761
- Testing
- Home-based exercises combined with cognitive training, Home-based exercises
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong