Clinical trials: Post Intensive Care Unit Syndrome
Physical Functional Impairment, Cognitive Impairment
PICS-p Longitudinal Cohort Study
Children who survive critical illness may develop new or worsening problems with physical health, cognitive status, emotional well-being, and social functioning.
- Conditions
- Physical Functional Impairment, Cognitive Impairment, Psychological Distress, Impaired Social Functioning
- Trial name
- PICSpLCS (NCT07876271)
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Fudan University
Post-Intensive Care Syndrome (PICS)
Long-Term Outcomes and Post-Intensive Care Syndrome: Investigating the Associations Between Metabolic Signatures and Physical Functioning in Critically Ill Patients
Despite being young, healthy, and physically fit, some intensive care unit (ICU) patients experience significantly worse functional recovery after critical illness than older patients with multiple comorbidities although a poor…
- Trial name
- TOPICS (NCT07170527)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- ARH van Zanten, MD PhD
Post-acute COVID-19 Syndrome, Long-COVID
Sociodemographic, Clinical, Quality of Life and Health Care Conditions in COVID-19 Survivors.
Sociodemographic, Clinical, Quality of Life, and Health Care Conditions After Hospital Discharge in Patients Who Required Admission to the Intensive Care Unit for COVID-19 at the Hospital Universitario Nacional Between April 2020…
- Conditions
- Post-acute COVID-19 Syndrome, Long-COVID, COVID-19, Long COVID
- Trial name
- NCT05185674
- Testing
- Exposure: Coronavirus disease 2019 (COVID-19)
- Where
- Colombia
- Volunteers
- 114 people
- Sponsor
- Javier Eslava
Delirium, Intensive Care Unit Delirium
Partnering With Family Members to Prevent, Detect and Manage Delirium in Critically Ill Patients.
Almost half of critically ill patients experience delirium. Delirium is associated with impaired cognition, mortality, and increased healthcare costs.
- Conditions
- Delirium, Intensive Care Unit Delirium, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- NCT04099472
- Testing
- Delirium Education, Prevention, and Management, Standard Care
- Where
- 4 sites in Canada
- Volunteers
- 128 people
- Sponsor
- University of Calgary
Critical Illness
Cortisol Levels as a Measure of Accumulated Physiological Stress in ICU Patients Undergoing Mechanical Ventilation
Critical illness is a situation of severe and prolonged stress for patients with mechanical ventilation (MV). Between 40-80% of these patients present the Post-ICU syndrome, a set of physical, cognitive, psychological alterations…
- Trial name
- Corti-COG (NCT03736135)
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Corporacion Parc Tauli
Critical Illness, Respiratory Failure
CONFOCAL-2 Interventional Pilot Study
This study is designed to assess the feasibility of identifying and administering individualized blood pressure targets early critical illness.
- Conditions
- Critical Illness, Respiratory Failure, Shock, Delirium
- Trial name
- NCT07296029
- Testing
- Autoregulation-based precision blood pressure management
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Queen's University
Quality of Life, Post ICU Syndrome
Prospective Evaluation of Psychological Consequences and Impact on Long-term Quality of Life
The goal of this observational study is to show the patient discomfort during their stay in intensive care is directly linked to the occurrence of a post ICU syndrome at 3 months.
- Trial name
- PICS (NCT06238557)
- Where
- France
- Volunteers
- 175 people
- Sponsor
- Romain Ronfle
Sepsis, Sepsis and Septic Shock
Written Sepsis Education for Patients
This pilot feasibility randomized controlled trial (RCT) aims to determine if it feasible to recruit, deliver, and evaluate a written discharge educational material (a brochure) to adult Intensive Care Unit (ICU) patients…
- Conditions
- Sepsis, Sepsis and Septic Shock, Sepsis at Intensive Care Unit
- Trial name
- NCT07415096
- Testing
- Written Discharge Education, Usual Care
- Volunteers
- 30 people
- Sponsor
- McMaster University
Quality of Life, Intensive Care Unit Syndrome
Patients´ Mental and Physical Health After Covid-19 Treated in ICU in Sweden
Covid-19 is a disease where both clinical experience and thus knowledge about the long-term effects of the disease are currently sparse.
- Trial name
- NCT06042790
- Where
- Sweden
- Volunteers
- 2,500 people
- Sponsor
- Swedish Intensive Care Registry
Coronavirus, Post Intensive Care Unit Syndrome
The Usability, Feasibility, and Tolerability of Virtual Reality for Rehabilitation From COVID-19
Patients who receive intensive care are known to be at high risk for physical, psychological, and cognitive impairments, a constellation known as PICS.
- Trial name
- COVRehab (NCT04505761)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Radboud University Medical Center
Post-Intensive Care Syndrome, Quality of Life
Post-ICU Syndrome Over Time in Patients With Respiratory Failure
Intensive Care Units (ICU) stabilize and maintain vital functions in critically ill patients, optimizing their survival. However, patients with prolonged stays may develop Post-ICU syndrome , characterized by physical, cognitive…
- Trial name
- PICUS2 (NCT06857513)
- Testing
- Questionnaire and Physical Exam, EuroQol 5-Dimension 3-Level, EuroQol Visual Analogue Scale (EQ-VAS)
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Acute Brain Injury, Cognitive Dysfunction
Cognitive Function and Health-related Quality of Life After Neuro-intensive Care
The study will provide information on cognitive impairment and Health related quality of life in patients surviving 12 months after acute brain injury, generate a hypothesis of useful variables to predict cognitive impairment or…
- Conditions
- Acute Brain Injury, Cognitive Dysfunction, Delirium, Sepsis
- Trial name
- COGNI (NCT04881097)
- Testing
- no intervention
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post Intensive Care Syndrome
Prevalence and Risk Factor of Post-intensive Care Syndrome in Neuro-ICU
Post-intensive care syndrome (PICS) is the set of disabling symptoms that can appear or worsen following a stay in intensive care. These symptoms are physical, cognitive, or psychiatric.
- Trial name
- STRESSréa (NCT06308835)
- Testing
- questionnaires
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep Apnea, Obstructive, Respiratory Insufficiency
Monitored Saturation Post-ICU
The overall aim with this project is to describe the correlation between measured and charted saturation after intensive care and also describe the saturation-pattern in these patients.
- Trial name
- NCT02290236
- Testing
- Pulseoximetry
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Karolinska University Hospital
Systemic Lupus Erthematosus, Childhood-onset Systemic Lupus Erythematous
Gyrotonic Exercise in Lupus Adolescents Who Survived From Intensive Care
lupus adoelscented who recently survive from intenive care unit usually complain postintenive care unit syndrome in addition to stress, fatigue, low life quality, depression, low physical performance, low grip strenght, insomnia…
- Conditions
- Systemic Lupus Erthematosus, Childhood-onset Systemic Lupus Erythematous, Intensive Care Unit Survivors, Adolescents
- Trial name
- NCT07833020
- Testing
- Gryotonic exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Delirium, Post ICU Syndrome
Delirium Phenotypes and Subsequent Impairment During Transition From ICU to Hospital Wards
The goal of this observational study is to learn about the disability profile during transition from ICU to hospital wards of delirium patients, including cognitive impairment, physical dysfunction and psychological disorders.
- Trial name
- NCT07193797
- Testing
- Phenotypes of ICU delirium
- Where
- China
- Volunteers
- 247 people
- Sponsor
- Shanghai Zhongshan Hospital
Multiple Trauma, Respiratory Distress Syndrome, Adult
Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma
Severe hypoxemia following trauma may happen in many circumstances (aspiration, ventilation-associated pneumonia, lung contusion...), most of which are not exclusively associated with a direct injury to the lungs.
- Trial name
- TRAUMADORNASE (NCT03368092)
- Testing
- Dornase Alfa Inhalant Solution [Pulmozyme]
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Cohort Studies, ICU Acquired Weakness (ICUAW)
Data Analysis and Physical Function Evaluation Index Development for Early Diagnosis and Monitoring of ICU-acquired Weakness
Data Analysis and Physical Function Evaluation Index Development for Early Diagnosis and Monitoring of ICU-acquired weakness
- Conditions
- Cohort Studies, ICU Acquired Weakness (ICUAW), Critical Illness
- Trial name
- Beyond ICU (NCT06669494)
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Samsung Medical Center
Post Intensive Care Unit Syndrome
Web-based Follow-up to Former ICU Patients
This study evaluates if a web-based 1-year programme is a useful method for follow-up intensive care survivors with short ICU-stay.
- Trial name
- WIVA (NCT04317144)
- Testing
- Web-based follow-up programme., No follow-up
- Where
- Sweden
- Volunteers
- 330 people
- Sponsor
- Uppsala University
Family Members, Post Intensive Care Unit Syndrome
Psychological Symptoms and Families of COVID-19 Patients
Families of patients in Intensive Care Units (ICUs) are at increased risk for developing psychological symptoms that can last for months after the patient is discharged.
- Conditions
- Family Members, Post Intensive Care Unit Syndrome, Post Traumatic Stress Disorder
- Trial name
- NCT04501445
- Testing
- Written Summary of Rounds
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Rush University Medical Center