Clinical trials: Post Mastectomy Pain Syndrome
Post-mastectomy Pain Syndrome
Evaluation and Re-evaluation of Post-mastectomy Pain Syndrome by Breast Cancer EDGE Task Force Outcomes
The purpose of the Breast Cancer EDGE Task Force is to provide physiotherapists with a comprehensive list of outcome measures that can be administered to a selected patient population, to assess post-mastectomy pain syndrome.
- Trial name
- NCT05458154
- Testing
- questionnaires
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Post-mastectomy Pain Syndrome
Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post-Mastectomy Pain
Given the burden of chronic postmastectomy pain and the need for effective, opioid-sparing analgesia, the propose of the randomized controlled trial is to evaluate the safety and efficacy of adding magnesium sulphate to the…
- Trial name
- NCT07438366
- Testing
- Pectointercostal Plane Block (PIPB), Erector Spinae Plane Block (ESPB), Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Breast Neoplasms
Combined Intra-articular Shoulder Injection and Stellate Ganglion Block in Chronic Post-mastectomy Shoulder Pain
Background and Purpose: Adhesive capsulitis of the shoulder is commonly found in patients after breast cancer treatment. We aimed to determine the effectiveness of combined shoulder joint intra-articular injection of platelet…
- Trial name
- NCT03586154
- Testing
- Platelet rich plasma, ketamine and bupivacaine injection
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Pain Syndrome, Pain
A Pilot Study Assessing the Effectiveness of Use of Guided Imagery for Treatment of Pain and Symptom Management in Women With Post-mastectomy Pain Syndrome
To learn if using guided imagery and deep breathing techniques can help with pain management in patients who have post-mastectomy pain syndrome.
- Conditions
- Pain Syndrome, Pain, Symptom Management
- Trial name
- NCT05408741
- Testing
- The Intervention Group, The Control Group
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Post-Mastectomy Chronic Pain Syndrome
Motor Cortex Versus Insula Stimulation Using Transcranial Current Stimulation on Chronic Post-mastectomy Pain
This study is designed to evaluate the effect of two concentric electrode transcranial direct current stimulation over the primary motor cortex versus insular cortical targets in post mastectomy neuropathic pain.
- Trial name
- NCT05544604
- Testing
- Transcranial direct current stimulation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- South Egypt Cancer Institute
Breast Cancer, Post-mastectomy Pain Syndrome
Incidence and Factors Affecting the Development and Outcome of Post Mastectomy Pain Syndrome
This multi-centre, prospective study aims to obtain a precise estimate of the local incidence of PMPS and identify biopsychosocial risk factors contributing to the development of PMPS.
- Trial name
- PMPS (NCT04989179)
- Where
- 3 sites in Singapore
- Volunteers
- 220 people
- Sponsor
- Singapore General Hospital
Breast Cancer Surgery, Postoperative Pain, Acute
Chronic Pain in Post-Mastectomy Patients; The Difference Between Pectoral Nerve (PECS I-II) and Erector Spinal Plane (ESP) Blocks
This study looks at two types of injections (called PECS and ESP blocks) to see which one works better for reducing pain after breast cancer surgery (mastectomy).
- Conditions
- Breast Cancer Surgery, Postoperative Pain, Acute, Postoperative Pain, Chronic, Post-mastectomy Pain Syndrome
- Trial name
- NCT06900842
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hacettepe University
Drug Effect
Comparison of Duloxetine Versus Pregabalin
Chronic post mastectomy pain syndrome (PMPS) is a chronic post-surgical neuropathic pain following breast cancer surgeries and lasting more than three months after surgeries.
- Trial name
- NCT04727502
- Testing
- Duloxetine, Pregablin
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute, Egypt
Duloxetine, Magnesium Sulphate
Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain
This study aims to evaluate the effect of combined duloxetine and IV Magnesium sulphate to decrease acute and chronic post mastectomy pain.
- Conditions
- Duloxetine, Magnesium Sulphate, Post-mastectomy Pain Syndrome
- Trial name
- NCT06087211
- Testing
- Magnesium sulphate and Duloxetine, Duloxetine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Breast Carcinoma
Myofascial Release or Trigger Point Injections for the Reduction of Post-Mastectomy Pain Syndrome
This clinical trial studies the effect of myofascial release in decreasing post-mastectomy pain compared to standard of care trigger point injections in patients with post-mastectomy pain syndrome.
- Trial name
- NCT05041751
- Testing
- Acupuncture Point Injection, Massage Therapy, Quality-of-Life Assessment
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
Targeted Nerve Surgery for the Prevention of Post-Mastectomy Pain Syndrome: A Randomized Trial
Post-Mastectomy Pain Syndrome (PMPS) is a chronic pain condition often caused by neuroma formation and nerve injury following breast cancer surgery.
- Trial name
- NCT07146009
- Testing
- Nerve Surgery, Standard of Care (Investigator Choice)
- Volunteers
- 60 people
- Sponsor
- Advanced Reconstructive Surgery Alliance
Chronic Pain
Does Pecs II Block Reduce the Incidence of Post Mastectomy Pain Syndrome (PMPS)? A Cross Sectional Study
Post mastectomy pain syndrome (PMPS) is a chronic pain condition that develops after breast cancer surgery. The objective of this study was to determine if Pecs II block administered prior to general anesthesia (GA) reduced the…
- Trial name
- PMPS (NCT04095897)
- Testing
- Pecs II Block
- Where
- Malaysia
- Volunteers
- 288 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Post-Mastectomy Chronic Pain Syndrome
Radiofrequency Thoracic Sympathectomy for Chronic Postmastectomy Pain; Randomized Placebo Controlled Study
Postmastectomy pain syndrome (PMPS) is a neuropathic pain that can follow surgical treatment for breast cancer, The antineuropathic medications (antidepressants and anticonvulsants) are disappointing and have low success rate.
- Trial name
- NCT03494426
- Testing
- radiofrequency thoracic sympathectomy, pregabalin ,tramadol,and tricyclic antidepressants
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Breast, Mastectomy, Segmental
Post-Breast Procedure Pain Syndrome Study
The purpose of this study is to better understand and characterize the pain that some patients experience after undergoing various breast surgeries, including breast biopsy, lumpectomy, mastectomy, mastectomy with reconstruction…
- Trial name
- NCT01114984
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Chronic Pain
Physical Exercise, Motor Activity and Depression in Post-mastectomy Pain Syndrome
Pain is an unpleasant sensation common to all those who undergo surgery. Several studies indicate that 40-60% of patients experience the post-operative experience and can be caused by both internal and external stimuli.
- Trial name
- NCT06123559
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Breast Neoplasms, Pain, Postoperative
Serratus Anterior Plane Block to Prevent Chronic Postoperative Pain in Breast Cancer
Chronic postoperative pain (CPP) remains a disturbing and obscure clinical problem. The hypothesis of this trial is that a peripheral block of the serratus anterior plane block type preoperatively after a modified radical…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic, Post-Mastectomy Chronic Pain Syndrome
- Trial name
- USB22 (NCT05494281)
- Testing
- Serratus Anterior Plane Block with local anesthetic, Serratus Anterior Plane Block with saline solution
- Where
- Morocco
- Volunteers
- 94 people
- Sponsor
- Moroccan Society of Surgery
Post-Mastectomy Chronic Pain Syndrome
Radiofrequency for Chronic Post-mastectomy Pain: is it Better to Target Intercostal Nerves or Corresponding Dorsal Root Ganglia?
neuropathic pain can occur following any surgical procedure on the breast ..
- Trial name
- NCT03374423
- Testing
- radiofrequency
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Dexamethasone, Glucocorticoids
High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy
The aim of this study is to investigate the effect of a single preoperative high-dose steroid injection on complications in the immediate postoperative phase after breast cancer surgery, with removal of the breast (mastectomy).
- Conditions
- Dexamethasone, Glucocorticoids, Mastectomy, Breast Cancer
- Trial name
- DEX-MAS (NCT03125941)
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ultrasound, Multilevel Erector Spinae Plane Block
Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastectomy Pain Syndrome for Breast Cancer Patients
The aim of this study is to compare the analgesic efficacy of multilevel erector spinae plane block (ESPB) vs thoracic epidural in modified radical mastectomy (MRM) regarding duration of analgesia, postoperative opioid…
- Conditions
- Ultrasound, Multilevel Erector Spinae Plane Block, Thoracic Epidural Analgesia, Post Mastectomy
- Trial name
- NCT06884852
- Testing
- Erector spinae plane block (ESPB), Thoracic epidural block
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Cancer Institute, Egypt
Breast Neoplasms, Pain, Postoperative
Persistant Post-mastectomy Pain in Breast Cancer : Incidence and Risk Factors
Post Mastectomy Pain Syndrome (PMPS) is a major complication of breast surgery responsible for depression and disability. The project consists of a prospective cohort on patients going for oncological breast surgery at National…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04676438
- Where
- 2 sites in Morocco
- Volunteers
- 722 people
- Sponsor
- Moroccan Society of Surgery