Clinical trials: Post Menopause
Post-menopausal Osteoporosis
Vitamin K as Additive Treatment in Osteoporosis
Vitamin K is thought to be important for bone health because it activates several proteins involved in bone formation. Poor dietary intake of vitamin K (mainly found in dark green leafy vegetables) is associated with bone loss…
- Trial name
- VITKANDOP (NCT01232647)
- Testing
- Phylloquinone, Menatetrenone (MK4)
- Where
- 2 sites in United Kingdom
- Volunteers
- 105 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Women, Age ≥45
Data Analysis to Evaluate Which Specific Gait Measures Are Associated with Risk of Injurious Falls Evaluating Gait Measures Associated with the Risk of Injurious Falls Through Data Analysis
The goal of this study is to understand if specific gait and activity measures can help predict injurious falls in older women. The main questions it aims to answer are: Can combining daily gait (DLG) and daily physical activity…
- Conditions
- Women, Age ≥45, After Menopause or Without Intention of Pregnancy
- Trial name
- WHS (NCT06644859)
- Testing
- Daily Activity Patterns Using Wearable Tri-Axial Sensors
- Where
- Israel
- Volunteers
- 17,466 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Menopause, Hypertension
Non-Comparative Study To Evaluate Changes In FMD After Quinapril Therapy In Hypertensive Women
ACE inhibitors are thought to modify the endothelium in a number of ways. Quinapril is an effective and well-tolerated ACE-I for the treatment of patients with hypertension and congestive heart failure.
- Trial name
- NCT00147524
- Testing
- quinapril, Laser Doppler imaging
- Where
- 5 sites in Hungary
- Volunteers
- 70 people
- Sponsor
- Pfizer
Cognitive Impairments, RRSO
LDX for the Treatment of Cognitive Functioning Issues in Women Post-Oophorectomy
This is a double-blind, placebo-controlled, study testing whether LDX improves cognitive function and EF in 20 postmenopausal women who report onset of cognitive difficulties after oophorectomy (with or without subsequent…
- Trial name
- LDX (NCT01986777)
- Testing
- lisdexamfetamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Breast Cancer
Collection of Efficacy and Safety Data of Chinese Patients Who Have Received Faslodex 250mg Treatment
This study is a post-authorisation study, committed to Center for Drug Evaluation (CDE) and China Food and Drug Administration (CFDA), in order to provide more effectiveness and safety data about Faslodex in real world clinical…
- Trial name
- NCT01425294
- Where
- 23 sites in China
- Volunteers
- 231 people
- Sponsor
- AstraZeneca
Breast Cancer
Exemestane With or Without ATN-224 in Treating Postmenopausal Women With Recurrent or Advanced Breast Cancer
RATIONALE: Exemestane may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. ATN-224 may stop the growth of breast cancer by blocking blood flow to the tumor.
- Trial name
- NCT00674557
- Testing
- SOD1 inhibitor ATN-224, exemestane, protein expression analysis
- Where
- United Kingdom
- Volunteers
- 111 people
- Sponsor
- Cancer Research UK
Menopause, Postmenopause
Buccal Estrogen in Toothpaste Study: Systemic Absorption of Estradiol When Administered Mixed With Toothpaste in Postmenopausal or Surgically Menopausal Women
Background: The use of estrogen in postmenopausal (or surgically menopausal) women is a common practice. Compliance is problematic in that estimates show only 1/3 of women use hormone replacement therapy (HRT) and only 30% are…
- Trial name
- NCT00029757
- Testing
- Estrogen
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Postmenopausal Symptoms
Efficacy Study Comparing 0.9 g and 1.25 g Estrogel With Placebo for Vasomotor Symptoms and Vulvar and Vaginal Atrophy
This study is intended to establish the lowest effective dose of EstroGel® for the treatment of vasomotor symptoms associated with menopause.
- Trial name
- NCT00160173
- Testing
- Estrogel
- Where
- 109 sites in United States
- Volunteers
- 221 people
- Sponsor
- ASCEND Therapeutics
Healthy
Role of Endogenous Estrogen in Growth-Hormone Regulation in Postmenopausal Women
Participants are being asked to take part in this research study to learn why growth hormone(GH) levels decline when estrogen production falls at the time of menopause.
- Trial name
- NCT01186796
- Testing
- Fulvestrant
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Neck Pain
Effect of Sensory Motor Training for Neck Muscles on Hand Grip Strength in Post-menopausal Fibromyalgia Neck Pain.
This study will be conducted to investigate the effect of sensory motor training for neck muscles on hand grip strength in post-menopausal fibromyalgia neck pain.
- Trial name
- NCT07624188
- Testing
- Neuro dynamic nerve gliding exercises, Sensory motor neck training
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Breast Cancer
Anastrozole and ZD 1839 in Treating Postmenopausal Women With Metastatic Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Anastrozole may fight breast cancer by blocking the production of estrogen by the tumor cells.
- Trial name
- NCT00049062
- Testing
- anastrozole, gefitinib
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Stress Urinary Incontinence
Vesair Clinical Trial
Single-blind, multicenter, randomized clinical trial of the Vesair Balloon in the treatment of Stress Urinary Incontinence in post-menopausal women
- Trial name
- VAPOR (NCT04026347)
- Testing
- Vesair Balloon
- Where
- 25 sites in United States
- Volunteers
- 158 people
- Sponsor
- Solace Therapeutics, Inc.
Vaginal Atrophy
Exploratory Study on Two Different Doses of VML-0001 on the Effects on Vaginal pH in Healthy Post-Menopausal Women
The study is designed to determine the effect on vaginal pH and the duration of action measured on the ability of the base formulation to reduce the vaginal pH
- Trial name
- NCT03770065
- Testing
- VML-0001
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Viramal Limited
Breast Cancer
Clinical Trial Assessing the Safety of Neoadjuvant Palbociclib in Combination With Endocrine Therapy
Patients with estrogen receptor positive (ER+) and/or progesterone receptor positive (PR+) breast cancer do not achieve good responses with pre-operative chemotherapy.
- Trial name
- NCT05069038
- Testing
- Palbociclib 125mg
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Nebraska
Osteoporosis
Bone Estrogen Strength Training
We started the Bone, Estrogen, Strength Training (BEST) study in the fall of 1995 at the University of Arizona, Tucson, Arizona. The BEST study is the largest of its kind.
- Trial name
- NCT00000399
- Testing
- Hormone replacement therapy, Strength training
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Menopause
Effects of Balance Exercises With and Without Clamshell Exercises After Menopause
Exercise-based balance intervention is structured program of physical exercises intended to enhance balance, stability, and clamshell exercises are known as an exercise-based balance intervention.
- Trial name
- NCT06750263
- Testing
- Balance exercise with clamshell, Balance exercise
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Osteoporosis, Postmenopausal
The Prevalence of Osteoporotic Vertebral Compression Fractures (OVCF) in Korean Post Menopausal Women
This is an observational study to investigate the prevalence of osteoporotic fractures in post menopausal patients. Post menopausal patients who visit OS(orthopedic surgery) including GHs(general hospitals) and clinics will be…
- Trial name
- TOP (NCT01381588)
- Testing
- Fracture evaluation
- Where
- South Korea
- Volunteers
- 1,136 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Osteoporosis
Efficacy of Cone Beam Computed Tomography in Diagnosing Osteoporosis
SUMMARY TITLE: "Efficacy of Cone Beam Computed Tomography derived radiomorphometric indices in screening of postmenopausal females for osteoporosis." RATIONALE: Osteoporosis is a disease of altered bone architecture affecting…
- Trial name
- NCT04365504
- Testing
- Dual energy X ray absorbtiometry
- Where
- India
- Volunteers
- 48 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Postmenopausal Symptoms
Relationship in Sleep With Low Back Pain in Postmenopausal Period
Introduction:The aim of this study was to investigate the incidence of low back pain in postmenopausal period and the relationship between low back pain and emotional state,sleep and quality of life i aimed at investigating low…
- Trial name
- NCT03640962
- Testing
- Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Osteoporosis, Post-Menopausal
Carotid Artery Intima-Media Thickness Following Exposure to Raloxifene or Placebo
The purpose of this study is to measure carotid artery IMT at a single visit in a subset of women previously enrolled in the CORE (H3S-MC-GGJY) trial
- Trial name
- NCT00532246
- Testing
- raloxifene
- Where
- 5 sites in United States
- Volunteers
- 147 people
- Sponsor
- Eli Lilly and Company