Clinical trials: Post Operative Complications
Postoperative Nausea and Vomiting
Comparison of TIVA (Total Intravenous Anesthesia) and TIVA Plus Palonosetron in Preventing Postoperative Nausea and Vomiting
A total intravenous anesthesia (TIVA) is a useful anesthetic technique that reduces the incidence of postoperative nausea and vomiting (PONV).
- Trial name
- NCT01478165
- Testing
- Total intravenous anesthesia, Total intravenous anesthesia plus palonosetron
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Incheon St.Mary's Hospital
Coronary Artery Disease, Systemic Inflammatory Response Syndrome
A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG
A comparison between precedex versus solumedrol as anti-inflammatory stress response inhibitors in patients undergoing on-pump CABG using different inflammatroy response parameters and the outcome of the drugs on the cognitive…
- Conditions
- Coronary Artery Disease, Systemic Inflammatory Response Syndrome, Postoperative Complications
- Trial name
- NCT07101367
- Testing
- Normal saline, Dexmedetomidine, Methylprednisolone
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Tonsillitis, Postoperative Pain
Does Ice Cream Help With Post-tonsillectomy Pain
Tonsillectomy is one of the most performed procedures in childhood, which carries with it certain postoperative problems, such as the pain of the operated area.
- Conditions
- Tonsillitis, Postoperative Pain, Cryotherapy Effect
- Trial name
- NCT04164511
- Testing
- 2 daily standard doses of vanilla-chocolate ice cream (cryotherapy)
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital Sestre Milosrdnice
Postoperative Pain
Pediatric Postoperative Pain Management in Surgical Wards - an Intervention Study
This study will explore healthcare providers' pediatric postoperative pain management knowledge and clinical practice. The aim of this study is to explore healthcare providers' knowledge and clinical practice in pediatric…
- Trial name
- NCT03987399
- Testing
- Tailored educational intervention
- Where
- Norway
- Volunteers
- 650 people
- Sponsor
- Oslo University Hospital
Endometriosis, Endometriosis-related Pain
The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery
The purpose of this study is to determine a difference in participant reported pain after endometriosis surgery in participants given oral metronidazole versus placebo.
- Trial name
- NCT04554693
- Testing
- Metronidazole Oral
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Pain, Postoperative, Acute Pain
EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial
The aim of the trial is to study the efficacy of continuous bilateral Erector Spinae Plane Block (ESPB) in managing perioperative pain in patients who undergo elective laparoscopic colectomy.
- Conditions
- Pain, Postoperative, Acute Pain, Postoperative Complications, Pain
- Trial name
- EFFECT (NCT04879004)
- Testing
- Ropivacaine injection
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Democritus University of Thrace
Shoulder Arthroscopy, Interscalene Brachial Plexus Block
Shoulder Anterior Capsular Block and Interscalene Brachial Plexus Block for Shoulder Arthroscopy
The aim of our study is to reveal a comparison between interscalene brachial plexus block and shoulder anterior capsular block with respect to their efficacy on pain relief during perioperative anesthetic management.
- Conditions
- Shoulder Arthroscopy, Interscalene Brachial Plexus Block, Shoulder Anterior Capsular Block, Rotator Cuff Rupture
- Trial name
- NCT05727345
- Testing
- Interscalene brachial plexus block, Shoulder anterior capsular block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Haseki Training and Research Hospital
Pain, Postoperative, Catheter Blockage
Comparison of Catheters Orifice Configuration For Continuous Infraclavicular Analgesia
Infraclavicular nerve catheter for postoperative analgesia will be included in the 70 adult patients undergoing upper extremity surgery included in the study.
- Conditions
- Pain, Postoperative, Catheter Blockage, Anesthesia
- Trial name
- NCT04205695
- Testing
- CEMP (closed-ended multiport catheter) group, OESP (open-ended single port catheter) group, Patient-controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Gulhane School of Medicine
Post Operative Pain, Spinal Surgery
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
The investigators propose a randomized, triple-blinded (patients, investigators, outcomes assessors), placebo-controlled pilot feasibility trial (Methadone to End Narcotic Dependence, MEND trial) to assess the feasibility and…
- Trial name
- MEND (NCT07222072)
- Testing
- Methadone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pain, Postoperative, Anxiety Preoperative
The Efficacy of a Mindfulness-Based Virtual Reality Intervention to Reduce Pain in Postoperative Patients
The goal of this randomized clinical trial is to evaluate whether a virtual reality (VR) mindfulness intervention can reduce anxiety and postoperative pain in adults undergoing surgery, primarily hernia and varicose vein…
- Trial name
- VR-MindPain (NCT06961695)
- Testing
- VR Mindfulness-Based Relaxation
- Volunteers
- 64 people
- Sponsor
- Babes-Bolyai University
Surgical Site Infections
Continuous v Bolus Infusion of Cefazolin During Ventral Hernia Repair
Patients undergoing an elective ventral hernia repair will be randomly assigned to receive either bolus infusion or continuous infusion of the cefazolin as the prophylactic antibiotic.
- Trial name
- NCT02666365
- Testing
- Bolus infusion of Cefazolin, Continuous infusion of Cefazolin
- Sponsor
- Milton S. Hershey Medical Center
Pain, Postoperative, Nerve Block
Use of Perioperative Pain Blocks In Urological Surgery
The study team aims to prospectively compare Placebo (local administration), ultrasound-guided transversus abdominis plane (UTAP) blocks, and laparoscopic-guided transversus abdominis plane (LTAP) blocks in patients undergoing…
- Conditions
- Pain, Postoperative, Nerve Block, Robotic Surgical Procedures
- Trial name
- NCT04426500
- Testing
- Bupivacain, Ultrasound-guided transversus abdominus plane block, Laparoscopic-guided transversus abdominus plane block
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain After Total Knee Arthroplasty, Pain, Postoperative
Comparison of BiFeS + ACB and IPACK + ACB Block Combinations for Postoperative Pain After Total Knee Arthroplasty
This prospective observational study will compare the postoperative analgesic efficacy of two multimodal regional anesthesia combinations routinely used after total knee arthroplasty (TKA) performed under spinal anesthesia.
- Conditions
- Pain After Total Knee Arthroplasty, Pain, Postoperative, Arthroplasty, Replacement, Knee
- Trial name
- NCT07231692
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
Postoperative Pain
The Analgesic Effect of QLB II After Robotic Prostatectomy. (QLB II: Quadratus Lomborum Block II Type)
The analgesic effects of Quadratus Lomborum Block II type after robotic-assisted laparoscopic radical prostatectomy, will be assessed.
- Trial name
- QLBII (NCT03941899)
- Testing
- Levobupivacaine in QLB II
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- San Salvatore Hospital of L'Aquila
Knee Arthropathy, Postoperative Pain
Optimization of a Fast-track Concept for Knee Joint Replacement
In an estimated 150,000 patients, a knee joint replacement is performed in Germany every year. The perioperative care of the patients aims at an optimal surgical technique, which leads to a high functionality in the joint, and…
- Conditions
- Knee Arthropathy, Postoperative Pain, Postoperative Complications
- Trial name
- KneeOptOut2 (NCT03920930)
- Testing
- Late local infiltration analgesia, Early local infiltration analgesia
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
Postoperative Pain, Hip Osteoarthritis
Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blocks for Hip Surgery Analgesia
This study aims to investigate the efficacy of adding a Posterior Pericapsular Deep gluteal block to two other standard nerve blocks-the Pericapsular Nerve Group block and the Lateral Femoral Cutaneous Nerve block-for patients…
- Conditions
- Postoperative Pain, Hip Osteoarthritis, Hip Fractures
- Trial name
- NCT07531030
- Testing
- Posterior Pericapsular Deep Gluteal, Pericapsular Nerve Group, and Lateral Femoral Cutaneous Nerve Blocks., Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blocks.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Remimazolam Besylate, Thoracoscopic Lobectomy
The Impact of Remimazolam Tosilate on Oxygenation and Postoperative Cognitive Function in Elderly Patients Undergoing Thoracoscopic Lobectomy
Background: During thoracoscopic lobectomy in elderly patients, one-lung ventilation (OLV) is a common procedure. However, this process is prone to cause hypoxemia and postoperative cognitive dysfunction (POCD), which seriously…
- Conditions
- Remimazolam Besylate, Thoracoscopic Lobectomy, Oxygenation, Postoperative Cognitive Dysfunction
- Trial name
- NCT07086911
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Jinqiao Qian
Delayed Recovery From Anesthesia
Automated Control of End-tidal Volatile Anesthetic Concentration
The new MIRUS system as well as the established AnaConDa system uses a reflector to conserve volatile anaesthetics (VA). Both systems act with commercially available ICU ventilators.
- Trial name
- MIRCONTROL (NCT02342509)
- Testing
- Desflurane, Sevoflurane, Isoflurane
- Volunteers
- 63 people
- Sponsor
- Ruhr University of Bochum
Postoperative Complications, Antibiotic Reaction
Complications After Lower Third Molar Surgery
Surgical removal of impacted mandibular wisdom teeth is a frequent intervention, usually accompanied by unpleasant sequelae (pain, swelling and trismus) in the postoperative period, sometimes even with possibly serious…
- Conditions
- Postoperative Complications, Antibiotic Reaction, Antibiotic Side Effect, Antibiotic Resistant Infection
- Trial name
- NCT05027893
- Testing
- Moxifloxacin 400 mg Oral Tablet, Cefixime 400 mg Oral Tablet
- Where
- Serbia
- Volunteers
- 157 people
- Sponsor
- University of Novi Sad
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.