Clinical trials: Post Operative Complications
Acute Pain, Chronic Pain
ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMY
The main aim of our study was to test the hypothesis that Erector spine plane block (ESP) with sedation will provide the similar employment of fentanyl and propofol during surgery as an infiltrative local anaesthesia with…
- Conditions
- Acute Pain, Chronic Pain, Postoperative Pain, Anesthesia
- Trial name
- NCT05483647
- Testing
- Local infiltrative anaesthesia, Erector spine plane block
- Where
- Ukraine
- Volunteers
- 52 people
- Sponsor
- Lviv National Medical University
Gynecologic Laparoscopic Surgery, Postoperative Pain
"Efficacy of Local Anesthetic for Postoperative Pain in Gynecologic Laparoscopy"
This is a randomized, double-blind, controlled clinical trial evaluating the efficacy of local anesthetic (LA) in reducing postoperative pain in patients undergoing gynecologic laparoscopic surgery.
- Conditions
- Gynecologic Laparoscopic Surgery, Postoperative Pain, Recovery Outcomes, Pain Management
- Trial name
- NCT07030647
- Testing
- Bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Usama Ahmed Elsaeed Salem, MD
Rectal Neoplasms
Defunctioning Cannula Ileostomy After Lower Anterior Resection of Rectal Cancer
Most surgeons suggest the use of fecal diverting to address the high morbidity and mortality associated with anastomotic leakage (AL) in patients with high risk factors on AL who are undergoing anterior resections.
- Trial name
- NCT01980238
- Testing
- cannula ileostomy, loop ileostomy, LAR
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Myocardial Infarction, ST-Elevation Myocardial Infarction (STEMI)
Intracoronary Hypothermia as a Prevention of Reperfusion Injury in Myocardial Infarction.
Acute myocardial infarction with ST segment elevation is often accompanied by a totally occluded coronary artery. Which has deleterious effects on heart muscle.
- Conditions
- Myocardial Infarction, ST-Elevation Myocardial Infarction (STEMI), Reperfusion Injury, Microvascular Occlusion
- Trial name
- NCT06567249
- Testing
- Intracoronary hypothermia, Standard percutaneous coronary intervention
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Postoperative Pulmonary Complications
Postoperative Pulmonary Complications in Major Abdominal Surgery
Incidence of Postoperative Pulmonary Complications (PPCs) varies from 2% to 19%, according to the population under examination and the criteria used to define pulmonary complications. There is no univocal definition of PPCs.
- Trial name
- NCT01701908
- Where
- 40 sites in Italy
- Volunteers
- 1,542 people
- Sponsor
- University of Udine
Bladder Cancer, Muscle-Invasive Bladder Carcinoma
Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy
Subjects will be randomized into 2 groups (stent or no stent) prior to radical cystectomy with ileal conduit urinary diversion (RCIC). They will follow the standard of care and be enrolled in the study for 12 months post-op.
- Conditions
- Bladder Cancer, Muscle-Invasive Bladder Carcinoma, Urothelial Carcinoma, Pelvic Malignancy
- Trial name
- NCT07234968
- Testing
- Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Thomas Jefferson University
Colorectal Surgery, Postoperative Complications
Restricted Fluid Therapy in Colorectal Surgery
This is a protocol for a trial carried out from 1999 to 2002. At that time, surgical patients received a large volume of intravenous saline during operations on the colon or the rectum, often so much fluid that their bodyweight…
- Trial name
- NCT03537989
- Testing
- Saline
- Volunteers
- 172 people
- Sponsor
- Holbaek Sygehus
Pain,Postoperative
Modified Thoracoabdominal Nerve Block(M-TAPA) in Total Laparoscopic Hysterectomies
The aim of the study is comparing the postoperative effects of ultrasound-guided Modified Perichondrial Approach to Thoracoabdominal Nerves (M-TAPA) block for postoperative pain control after total laparoscopic hysterectomy.
- Trial name
- NCT06601413
- Testing
- M-TAPA Block, Trocar site local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Gulhane Training and Research Hospital
Obesity, Hyperoxia
Evaluation of the Risk of Hyperoxia-induced Hypercapnia in Obese Cardiac Surgery Patients
This study aims to evaluate the risk of hyperoxia-induced hypercapnia in post-op obese cardiac surgery patients. It will compare two oxygenation modes in terms of their effect on the arterial partial pressure of carbon dioxide…
- Conditions
- Obesity, Hyperoxia, Hypercapnia
- Trial name
- NCT02917668
- Testing
- FreeO2, Usual care
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Postoperative Cognitive Dysfunction, Postoperative Delirium
Postoperative Cognitive Dysfunction in Elderly Urologic Oncology Patients (POCD)
Postoperative cognitive changes are more common in elderly patients, which can result in poor quality of life, loss of workforce, disability, early retirement, physical-social dependence, increased health care cost and premature…
- Conditions
- Postoperative Cognitive Dysfunction, Postoperative Delirium, Frailty
- Trial name
- POCD (NCT04837391)
- Testing
- Near Infrared Spectroscopy (NIRS), Blood sample, Addenbrooke Cognitive Examination III (ACE-III)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University
Pain, Postoperative
Erector Spinae Plane Block vs Erector Spinae Plane Block With Serratus Anterior Plane Block in Thoracic Surgery
This pilot study will prospectively compare continuous Erector Spinae Plane block (ESP) versus combination of continuous Erector Spinae Plane block and single shot Serratus Anterior Plane block for post-operative pain management…
- Trial name
- NCT04349774
- Testing
- Control Group - ESP block with SAP block, Treatment Group - ESP block with SAP normal saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Anna Uskova
Degenerative Disc Disease, Herniated Disc
Bone Graft Materials Observational Registry
A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and "real world" use of approved and commercially available bone graft substitutes, autograft and allograft.
- Conditions
- Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis
- Trial name
- APPROACH-001 (NCT00974623)
- Testing
- Bone graft substitute, autograft or allograft
- Where
- 14 sites in United States, Hungary and 1 more
- Volunteers
- 329 people
- Sponsor
- Baxter Healthcare Corporation
Lipid Metabolism Disorders, Postoperative Complications
Pre-operative Blood Lipid Level and Post-operative Major Adverse Cardiac Event
Whether the pre-operative blood lipid level and post-operative cardiovascular events is associated is unknown. This study is to find out the main blood lipid and relative protein level change and the post-operative cardiovascular…
- Trial name
- NCT03344224
- Testing
- laboratory test
- Volunteers
- 50,000 people
- Sponsor
- Peking University First Hospital
Epithelial Ovarian Cancer
Phase III Trial of Stage I Ovarian Cancer After Surgery
To compare the Overall survival of adjuvant chemotherapy versus observation in stage I epithelial ovarian cancer after comprehensive staging surgery
- Trial name
- NCT04063527
- Testing
- adjuvant chemotherapy
- Where
- 103 sites in Japan, South Korea
- Volunteers
- 360 people
- Sponsor
- Japanese Gynecologic Oncology Group
Procedural Sedation, Emergence Delirium
Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine
The purpose of this study is to determine if positive imagery therapy while using ketamine in procedural sedation reduces the number of emergence reactions and impacts pre and post-procedural anxiety.
- Trial name
- NCT04746079
- Testing
- Positive Imagery Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Free Gingival Graft, Survey and Questionnaire
Free Gingival Graft Patients' Treatment Perception and Experience
Free gingival graft (FGG) is a common and effective periodontal procedure used to improve gum health; however, it can involve challenges such as postoperative pain and discomfort due to the requirement of a secondary donor site.
- Conditions
- Free Gingival Graft, Survey and Questionnaire, Postoperative Pain
- Trial name
- NCT07568327
- Testing
- Free Gingival Graft
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Constipation, Post-Op Complication
Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy
The hypothesis is that starting a bowel regimen with Polyethylene Glycol prior to robotic assisted sacrocolpopexy will decrease time to first bowel movement after surgery.
- Trial name
- NCT04197869
- Testing
- Polyethylene Glycol Powder
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Tonsillectomy, Tonsillitis Chronic
BiZact Tonsillectomy in the Pediatric Population
This study has been designed to evaluate how effective the Bizact tonsillectomy device is in reducing operating time and complications that occur after surgery.
- Conditions
- Tonsillectomy, Tonsillitis Chronic, Hemorrhage, Postoperative Pain
- Trial name
- NCT04725305
- Testing
- BiZact, Standard of care
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Baylor College of Medicine
Diaphragmatic Paralysis, Postoperative Pain
Hemidiaphragmatic Paralysis With Diluted Continuous Interscalene Plexus Infusions
Interscalene brachial plexus block (ISB) constitutes the analgesic criterion standard for shoulder surgery. However, it is associated with a high incidence of hemidiaphragmatic paralysis (HDP) that may not be tolerated by…
- Conditions
- Diaphragmatic Paralysis, Postoperative Pain, Acute Pain, Shoulder Pain
- Trial name
- NCT03592056
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Clinica las Condes, Chile
Colectomy, Open Surgery
Perioperative Intravenous Nimodipine Trial
The role of perioperative IV administration of nimodipine, an L-type calcium channel antagonist which is capable of crossing the blood-brain barrier, on peri-operative opioid and anesthetics requirements, pain intensity…
- Conditions
- Colectomy, Open Surgery, Pain, Pain, Postoperative
- Trial name
- NCT07048522
- Testing
- Nimodipine, Isotonic Saline
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Ioannina
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