Clinical trials: Post Operative Pain, completed
Pain, Postoperative, Nerve Block
Use of Perioperative Pain Blocks In Urological Surgery
The study team aims to prospectively compare Placebo (local administration), ultrasound-guided transversus abdominis plane (UTAP) blocks, and laparoscopic-guided transversus abdominis plane (LTAP) blocks in patients undergoing…
- Conditions
- Pain, Postoperative, Nerve Block, Robotic Surgical Procedures
- Trial name
- NCT04426500
- Testing
- Bupivacain, Ultrasound-guided transversus abdominus plane block, Laparoscopic-guided transversus abdominus plane block
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain After Total Knee Arthroplasty, Pain, Postoperative
Comparison of BiFeS + ACB and IPACK + ACB Block Combinations for Postoperative Pain After Total Knee Arthroplasty
This prospective observational study will compare the postoperative analgesic efficacy of two multimodal regional anesthesia combinations routinely used after total knee arthroplasty (TKA) performed under spinal anesthesia.
- Conditions
- Pain After Total Knee Arthroplasty, Pain, Postoperative, Arthroplasty, Replacement, Knee
- Trial name
- NCT07231692
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Postoperative Pain
The Analgesic Effect of QLB II After Robotic Prostatectomy. (QLB II: Quadratus Lomborum Block II Type)
The analgesic effects of Quadratus Lomborum Block II type after robotic-assisted laparoscopic radical prostatectomy, will be assessed.
- Trial name
- QLBII (NCT03941899)
- Testing
- Levobupivacaine in QLB II
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- San Salvatore Hospital of L'Aquila
Knee Arthropathy, Postoperative Pain
Optimization of a Fast-track Concept for Knee Joint Replacement
In an estimated 150,000 patients, a knee joint replacement is performed in Germany every year. The perioperative care of the patients aims at an optimal surgical technique, which leads to a high functionality in the joint, and…
- Conditions
- Knee Arthropathy, Postoperative Pain, Postoperative Complications
- Trial name
- KneeOptOut2 (NCT03920930)
- Testing
- Late local infiltration analgesia, Early local infiltration analgesia
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
Breast Cancer, Breast Cancer Female
Factors Affecting Functionality in Breast Cancer Survivors
Breast cancer is the most frequent cancer type in women globally. In conjunction with the new developments, breast cancer survival has increased therefore the management of long-term complications has gained importance.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Cancer Lymphedema, Breast Carcinoma in Situ
- Trial name
- NCT04245657
- Testing
- Tissue Dielectric Constant Measurement, Muscle strength measurement, Hand-Grip Strength Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Izmir Bakircay University
Failed Back Surgery Syndrome, Chronic Pain
Study on Failed Back Surgery Syndrome Pathway Optimization: A Focus on Patient Identification, Chronicization Factors and Outcome Predictors
This pilot study is part of a global project that aims to better define and understand features of FBSS/POPS "post-operative persistent syndrome patients (shortened as "FBSS" in the following project).
- Trial name
- PREDIBACK (NCT02964130)
- Testing
- No name
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital
Post Operative Pain, Opioid Use
Opioid Use After Urogynecologic Procedures: Using a Predictive Calculator
The purpose of this study is to determine if the investigators can precisely predict how much pain medication the subjects will need after surgery using a special calculator that was developed for this purpose.
- Conditions
- Post Operative Pain, Opioid Use, Prolapse Genital
- Trial name
- NCT05571072
- Testing
- Opioid calculator, Standard opioid prescription
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- David Sheyn
Perioperative Complication, Nursing Caries
The Effects of Listening Music During Breathing Exercises
Background and purpose : This study aims to analyze the effects of listening to music during deep breathing and coughing exercises on vital sings and pulmonary functions in patients, who underwent video assisted thoracoscopic…
- Conditions
- Perioperative Complication, Nursing Caries, Pain, Postoperative
- Trial name
- NCT05329519
- Testing
- Listening music
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Pain, Postoperative, Obesity
Bilateral Thoracic Paravertebral Blocks in Obese and Non-obese Patients Undergoing Reduction Mammaplasty
Aim: Although regional anesthesia (RA) techniques are advantageous in the anesthetic management of obese patients (body mass index (BMI)≥30); their performances can still be associated with technical difficulties and greater…
- Conditions
- Pain, Postoperative, Obesity, Thoracic Paravertebral Blocks, Ultrasound
- Trial name
- NCT04596787
- Testing
- Bilateral Thoracic paravertebral block
- Volunteers
- 82 people
- Sponsor
- Istanbul University
Post Operative Pain
Addition of MgSO4 or Dexamethasone to Bupivacaine on the Prolongation of Ultrasound-guided Quadratus Lumboram Block
The goal of postoperative pain management is the provision of comfort, early mobilization and improved respiratory function without causing inadequate sedation and respiratory compromise, which can be achieved through using…
- Trial name
- NCT05397236
- Testing
- Bupivacaine- Magnesium, Bupivacaine dexamethasone, Bupivacaine saline
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Pain, Postoperative, Thoracic Surgery, Video-Assisted
Thoracic Paravertebral Block, Erector Spinae Plane Block, and in Combined Paravertebral-erector Spinae Block
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Pain, Postoperative, Thoracic Surgery, Video-Assisted, Thoracic Paravertebral Block, Erector Spinae Plane Block
- Trial name
- NCT04929665
- Testing
- Two different block and combination of these two blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Analgesia
Extended Delivery of Bupivacaine Study in Herniorrhaphy
This is a phase 4, randomized, open-label study of the efficacy, safety, and pharmacokinetics of bupivacaine administered as liposomal bupivacaine or continuous infusion via elastomeric pump following unilateral open inguinal…
- Trial name
- NCT04102267
- Testing
- Bupivacaine liposome injectable suspension, Bupivacaine HCl without epinephrine via continuous infusion
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Heron Therapeutics
Postoperative Pain
An Efficacy and Safety Study to Compare Morphine 6-glucuronide (M6G) and Morphine in Patients Suffering With Post-Operative Pain for at Least 24 Hours
To compare the incidence and severity of nausea in the study treatment groups, during the 18-hour period starting 6 hours after titration to pain relief; following confirmation of the assumption of non-inferiority between the two…
- Trial name
- NCT01082471
- Testing
- Morphine 6-glucuronide, Morphine
- Where
- 7 sites in Czechia, France and 4 more
- Volunteers
- 517 people
- Sponsor
- Paion UK Ltd.
Pain, Postoperative, Abdominal Surgery
Erector Spinae Plane Block Versus Oblique-Subcostal Transversus Abdominis Plane Block in Emergency Abdominal Surgery with Midline Incision
Most of the recommendations regarding pain management in emergency abdominal surgery are extracted from data from elective abdominal surgery.
- Conditions
- Pain, Postoperative, Abdominal Surgery, Emergency
- Trial name
- NCT06448299
- Testing
- TAPB, ESPB
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Kasr El Aini Hospital
Postoperative Pain
Gabapentin and Diclofenac Sodium Comparison for Post-Operative Pain Relief
Little is known about comparative efficacy of gabapentin and diclofenac sodium in managing post-operative pain. Therefore, this study was planned to compare the efficacy of gabapentin, and diclofenac sodium for post-operative…
- Trial name
- NCT07267182
- Testing
- Gabapentin 600mg, Diclofenac Sodium 100 MG
- Where
- Pakistan
- Volunteers
- 240 people
- Sponsor
- Muhammad Aamir Latif
Ligamentoplasty, Anterior Cruciate Ligament (ACL)
A Study Aiming to Demonstrate That the Addition of Intravenous (IV) Tranexamic Acid-Compared to Placebo-During Anterior Cruciate Ligament (ACL) Reconstruction Results in Reduced Blood Loss and Postoperative Pain.
Various reconstruction and graft harvesting techniques are used for ACL reconstruction. The most common techniques involve harvesting one or more hamstring tendons.
- Trial name
- EXACYLCA (NCT07753161)
- Testing
- ACL reconstruction
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Postoperative Pain, Obstetric Pain
Lidocaine Patches After Cesarean Section
The aim of this study is to investigate the impact of using lidocaine patches after cesarean section on pain control and opioid use in the immediate post-operative period.
- Conditions
- Postoperative Pain, Obstetric Pain, Opioid Use
- Trial name
- LPACS (NCT04443569)
- Testing
- Lidocaine patch
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Yale University
Pain
A Study of TRV130 for the Treatment of Pain After Abdominoplasty
The primary objective is to evaluate the analgesic efficacy of IV TRV130 compared with placebo in patients with acute postoperative pain following abdominoplasty.
- Trial name
- NCT02335294
- Testing
- TRV130, Morphine
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Trevena Inc.
Postoperative Pain After Breast Reconstruction With Abdominal Flap
Postoperative Pain Control With Fentanyl Patch in Patients Undergoing Mastectomy and TRAM or DIEP Flap Reconstruction
The aim of this randomized, double-blind controlled trial is to determine the efficacy of transdermal fentanyl for the management of early postoperative pain in women undergoing mastectomy followed by immediate TRAM or DIEP flap…
- Trial name
- Fentanyl Patch (NCT01258296)
- Testing
- Fentanyl, Inactive patch
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Postoperative Pain
Femoral or Sciatic Nerve Block to Provide Analgesia After Proximal Tibial Osteotomy
Proximal tibial osteotomy is associated with moderate to severe postoperative pain. The proximal part of the tibia is innervated by branches from the femoral nerve anteriorly and the sciatic nerve posteriorly.
- Trial name
- NCT05728294
- Testing
- Femoral nerve block with ropivacaine 0.5%, 20 ml, Sciatic nerve block with ropivacaine 0.5%, 20 ml
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
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