Clinical trials: Post Operative Pain, completed
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT05447455
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Ankle Fracture
Liposomal Bupivacaine With Bupivacaine in Ankle Fracture Open Reduction Internal Fixation (ORIF)
This study is a randomized controlled trial assessing pain control in ankle fractures repaired with open reduction and internal fixation.
- Trial name
- NCT02480621
- Testing
- Liposomal Bupivacaine with Bupivacaine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Jamaica Hospital Medical Center
Pain, Postoperative
Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management: A Pilot Study
Overall Aim: To evaluate the feasibility and potential benefits of investigating bilateral continuous erector spinae blocks (BESB) for postoperative pain management in a small cohort of children undergoing surgical sternotomy…
- Trial name
- NCT03936387
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pain
Postoperative Effects of Chewing Gum, Ibuprofen and Acetaminophen on Pain After Initial Archwire Placement
The purpose of this study is to compare the efficacy of ibuprofen, acetaminophen, chewing gum in reducing orthodontic pain. This study include 81 patients to be classified into 4 groups of 19 each: ibuprofen (400 mg)…
- Trial name
- PECI (NCT03568721)
- Testing
- Ibuprofen, Acetaminophen, Chewing gum
- Where
- Brazil
- Volunteers
- 81 people
- Sponsor
- Rio de Janeiro State University
Pain
The Effect of Ultra-low-dose Naloxone on Remifentanil-induced Postoperative Hyperalgesia - A Randomized Controlled Study
High-dose remifentanil infused intraoperative ironically results in postoperative hyperalgesia. Ultra-low dose nalxone is demonstrated to prevent these opioid-induced hyperalgesia in animal model.
- Trial name
- NCT02856087
- Testing
- High dose Remifentanil, Naloxone, Low dose remifentanil
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Colon Cancer, Rectal Cancer
The Effect of Dexmedetomidine on Postoperative Analgesia
The purpose of this study is to determine whether additional Dexmedetomidine to patient controlled analgesia can reduce fentanyl consumption.
- Trial name
- NCT01373021
- Testing
- Fentanyl, Dexmedetomidine
- Where
- South Korea
- Volunteers
- 95 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain
Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia
Morphine is usually used for pain relief after cesarean delivery. However, sometimes it is not available, the patient might be allergic to morphine or intolerant to its side effects.
- Trial name
- NCT03592992
- Testing
- Spinal Hydromorphone, Spinal Morphine
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Nausea and Vomiting, Postoperative Pain
Dexamethasone Improves Postoperative Symptoms After Laparoscopic Cholecystectomy
Dexamethasone has been reported to reduce postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy (LC). However, its effects on other surgical outcomes such as pain and fatigue have been unclear.
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Postoperative Fatigue
- Trial name
- dxt (NCT01030614)
- Testing
- Dexamethasone
- Where
- Mexico
- Volunteers
- 210 people
- Sponsor
- Instituto Mexicano del Seguro Social
Photorefractive Keratectomy
A Comparison of Topical Nepafenac to Placebo in Corneal Epithelial Healing Times and Postoperative Pain Relief
The purpose of this study is to compare healing times and subjective pain level responses of nepafenac to placebo after photo refractive keratomileusis (PRK) surgery.
- Trial name
- NCT00330798
- Testing
- nepafenac 0.1%, ketorolac 0.4%
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Tooth Extraction Site Healing
Effect of a Bioactive Mineral-Ionic Mouthrinse on Periodontal Soft Tissue Healing
This randomized, double-blinded clinical trial was designed to evaluate the effects of a bioactive mineral-ionic mouthrinse (THERAVEX® Total Oral Care Plus) on postoperative healing and patient comfort following simple tooth…
- Trial name
- Bioactive Mine (NCT07611123)
- Testing
- Normal Saline, chlorhexidine (CHX), Theravex Bioactive Solutions (Tissue Care Plus and Oral)
- Where
- Saudi Arabia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Knee Osteoarthritis
Efficacy Study of Pre-emptive Etoricoxib for Postoperative Pain and Functional Outcome in Total Knee Arthroplasty
The purpose of this study is to study the efficacy of pre-emptive etoricoxib in reducing post-operative pain and improving function outcome after a total knee arthroplasty.
- Trial name
- NCT01246362
- Testing
- Control, Etoricoxib
- Where
- Singapore
- Volunteers
- 65 people
- Sponsor
- Singapore General Hospital
Pain
Parasternal Nerve Block Using Bupivacaine for Postoperative Analgesia in Children Undergoing Cardiac Surgery
All pediatric patients who undergo cardiac surgery require analgesic medications for postoperative pain control and many require sedation to facilitate comfort with cares.
- Trial name
- NCT02512861
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Pain
Ear Acupuncture for Pain Associated With Ambulatory Arthroscopic Knee Surgery
The investigators propose to complete a randomized controlled trial to compare ear acupuncture at Cingulate gyrus, thalamus, omega 2, shen-men, and point zero on the right and left ear plus standard of care versus standard of…
- Trial name
- BFAKnee (NCT01447329)
- Testing
- Ear Acupuncture, Standard Treatment
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
Chronic Pain
Central Nervous System Amplification in Lumbar Failed Back Surgery Syndrome
The purpose of this study is to learn whether or not certain risk factors and patient characteristics are linked with and possibly can predict the development of chronic pain after lumbar spine surgery.
- Trial name
- NCT03444168
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Thoracotomy Analgesia, Intrathecal Morphine
Intrathecal Morphine and Opioid Consumption After Thoracotomy
Thoracotomy is associated with some of the most severe postoperative pain of any surgical procedure. Inadequate analgesia restricts inspiratory effort and impairs the ability to cough, predisposing patients to atelectasis…
- Conditions
- Thoracotomy Analgesia, Intrathecal Morphine, Quality of Recovery (QoR-15), Opioid Consumption, Postoperative
- Trial name
- NCT07790250
- Testing
- İntercostal nerve block, Intrathecal Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Hallux Valgus
A Study to Evaluate the Effectiveness and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain From Bunionectomy Compared With Placebo
The purpose of this study is to evaluate the analgesic efficacy and safety of tapentadol immediate-release (IR [CG5503]) for use in the relief of moderate to severe acute pain, compared with placebo, in adult Taiwanese patients…
- Trial name
- NCT01813890
- Testing
- Tapentadol IR 50 mg, Tapentadol IR 75 mg
- Where
- 3 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Janssen-Cilag International NV
Postoperative Pain
Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section
The cesarean section is one of the most commonly performed surgeries in the world and it represents 20% of the births in France. Postoperative pain is moderate-to-severe during the first 48 hours after this procedure.
- Trial name
- ROMANCE (NCT02410317)
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Grenoble
Acute Appendicitis
Laparoscopic-Assisted TAP Block VErsus Trocar-site Infiltration After Laparoscopic Appendectomy
This randomized controlled trial compared laparoscopic-assisted transversus abdominis plane (TAP) block with trocar-site local anesthetic infiltration for postoperative pain management in adult patients undergoing laparoscopic…
- Trial name
- NCT07849751
- Testing
- laparoscopic-assisted transversus abdominis plane block, trocar-site local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pain
Patient Controlled Analgesia Pharmacogenetic Study
The purpose of this research study is to identify factors and genes (the nucleic acid material that determines the makeup of the human body) that may be associated with acute and chronic post-surgical pain as well as develop…
- Trial name
- NCT01731873
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asymptomatic Apical Periodontitis
Postoperative Pain and Quality of Life Following Root Canal Treatment With Two Different Sealers
This study compares two different root canal sealers, AH Plus and BioRoot Flow, to determine whether the type of sealer used during root canal treatment affects pain after treatment and oral health-related quality of life.
- Trial name
- NCT07884799
- Testing
- AH Plus, BioRoot Flow
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Karadeniz Technical University
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