Clinical trials: Post Operative Pain, completed
Postoperative Pain
Effect of Intrathecal vs Intraarticular Dexmedetomidine on Postoperative Pain Following Arthroscopy
Comparison between intrathecal Dexmedetomidine versus Intraarticular Dexmedetomidine on postoperative pain after knee arthroscopy.
- Trial name
- NCT02581566
- Testing
- Intrathecal Dexmedetomidine, Intraarticular Dexmedetomidine, Bupivacaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Pain, Postoperative
Tropisetron on Postoperative Pain
The role of 5-HT3A receptors in nociceptive processing has been demonstrated in several animal models. However, studies in human volunteers have not been reported except for one recent study suggesting that ondansetron could…
- Trial name
- NCT01304953
- Testing
- Group P+P, Group P+T, Group S+P
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Huazhong University of Science and Technology
Obesity, Pain, Postoperative
Laparoscopic TAP Block for Sleeve Gastrectomy: Does Timing Matter
The goal of this study is to investigate whether an early intraoperative transverse abdominis plane block (TAP block) will provide superior analgesia to a late intraoperative TAP block.
- Trial name
- NCT04787367
- Testing
- TAP block
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Arthur Carlin
Hip Fractures, Hip Injuries
Iliopsoas Plane Block vs PENG Block for Hip Arthroplasty
Hip arthroplasty is one of the most common orthopedic procedures especially in elderly patients due to deformation of joints. Patients may complain of severe pain due to surgical trauma and prosthesis.
- Conditions
- Hip Fractures, Hip Injuries, Hip Arthropathy
- Trial name
- NCT05397145
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Pain, Postoperative, Breast Cancer
Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early…
- Trial name
- NCT03799757
- Testing
- 40ml of 0.25% bupivacaine, 40ml of 0.9% normal saline
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Alexandria University
Postoperative Pain, Postoperative Nausea and Vomiting
A Study to Assess Analgesic Efficacy of Intravenous Lignocaine
The primary objectives of this study are to analyse the effect of perioperative systemic infusion of lignocaine on postoperative pain, postoperative nausea and vomiting and perioperative levels of inflammatory mediators in…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Postoperative Ileus
- Trial name
- NCT01699919
- Testing
- Intravenous lignocaine
- Where
- India
- Volunteers
- 134 people
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Pain
Ultrasound Guided Quadratus Lumborum Block for Postoperative Pain in Abdominoplasty
The original concept of a quadratus lumborum block (QLB) indicated for analgesia after abdominal surgery was first described by Blanco in 2007.
- Trial name
- NCT02932930
- Testing
- QLB bloc, 0.2% Ropivacaine, 0.9% normal saline
- Where
- Lebanon
- Volunteers
- 40 people
- Sponsor
- St Joseph University, Beirut, Lebanon
Pain, Postoperative, Anxiety
The Effect of Acupressure on Procedural Pain, Anxiety and Hemodynamic Variables During Chest Tube Removal
When the literature was reviewed, many studies were found in which various non-pharmacologic interventions such as reflexology, music therapy, slow and deep breathing exercises, relaxation exercises and cold application were…
- Conditions
- Pain, Postoperative, Anxiety, Hemodynamic Instability
- Trial name
- NCT05875337
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mersin University
Postoperative Pain
Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)
This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in…
- Trial name
- NCT03237481
- Testing
- HTX-011, Bupivacaine HCl, Luer-lock applicator
- Where
- 24 sites in United States, Belgium
- Volunteers
- 418 people
- Sponsor
- Heron Therapeutics
Pain, Postoperative
Epidemiology Study and Risk Factor Analysis on Chronic Post-surgical Pain After Video-assisted Thoracic Surgery
This study is a nationwide multi-center study to investigate the incidence and risk factors of chronic post-surgical pain (CPSP) after receiving video-assisted thoracic surgery (VATS).
- Trial name
- NCT05473728
- Where
- China
- Volunteers
- 886 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
ACL Injury, Post Operative Pain
iPACK for Post-op Pain Following ACL Reconstruction
This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft.
- Trial name
- NCT05498870
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Medical University of South Carolina
Knee Osteoarthritis, Pain, Postoperative
Premedication with Intranasal Dexmedetomidine in Sedation of Patients Undergoing Total Knee Arthroplasty
This study aims to find out if preoperatively given dexmedetomidine is effective analgesic adjuvant for treating postoperative pain in patients undergoing elective total knee arthroplasty (TKA).
- Trial name
- TKADEX (NCT04859283)
- Testing
- Dexmedetomidine
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Acute Post-operative Pain, Cholecystectomy, Laparoscopic
Optimizing Pain Management Following Laparoscopic Cholecystectomy RCT
evaluating the two final steps we added to optimize post laparoscopic cholecystectomy pain management.
- Conditions
- Acute Post-operative Pain, Cholecystectomy, Laparoscopic, Pain Assessment Pain Intensity, Pain Intensity
- Trial name
- Pain (NCT05214157)
- Testing
- active gas aspiration
- Where
- Egypt
- Volunteers
- 804 people
- Sponsor
- Zagazig University
Opioid Use, Pain, Postoperative
Ibuprofen and Acetaminophen Versus Ibuprofen and Acetaminophen Plus Hydrocodone for Analgesia After Cesarean Section
Postpartum patients delivered by cesarean section will be randomized to NSAIDS Vs NSAIDS plus opioid
- Trial name
- IVY (NCT03372382)
- Testing
- Ibuprofen, Acetaminophen, Norco
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Knee Osteoarthritis, Arthropathy of Knee Joint
Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia
Previous retrospective database studies suggest that total knee arthroplasty (TKA) surgery under spinal anesthesia has less complications than when performed under general anesthesia.
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee Joint, Knee Pain Chronic, Rheumatoid Arthritis
- Trial name
- NCT03364088
- Testing
- Spinal anesthesia with tourniquet, Spinal anesthesia without tourniquet, General anesthesia with tourniquet
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Riku Antero Palanne
Blood Flow Restriction and Low-Intensity Resistance Training, Meniscal Injuries
Blood Flow Restriction Training After Meniscus Surgery
This study was conducted to investigate the effects of combined low-intensity resistance exercise with blood flow restriction (BFR-LIRE) on muscle strength, pain, and fear of movement in individuals who had undergone…
- Trial name
- NCT07299461
- Testing
- Traditional physical therapy exercises and physical therapy modalities, Traditional physical therapy exercises and physical therapy modalities + low-intensity resistance exercise with blood flow restriction (BFR-LIRE)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Uskudar University
Post Operative Pain
Evaluation of Postoperative Pain and Bacterial Load Reduction With ProTaper Ultimate Versus ProTaper Gold Rotary Systems
This study aims to research the effect of different instrument designs by comparing protaper ultimate versus protaper gold systems on root canal preparation by evaluating post-operative pain and bacterial count reduction…
- Trial name
- NCT05305742
- Testing
- Instrument Design
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Cairo University
Coronary Artery Disease, Angina Pectoris
An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery
The primary objective of this study is to evaluate sternal bone healing following a full median sternotomy versus standard of care for sternal closure with wire cerclage.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Cardiac Valve Disease
- Trial name
- SB (NCT01783483)
- Testing
- SternaLock Blue closure system, Suture Wire
- Where
- 12 sites in United States
- Volunteers
- 236 people
- Sponsor
- Zimmer Biomet
Pain Management in Breast Surgery, Pain After Surgery
Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block
This prospective randomized study will compare the effects of Erector Spinae Plane Block (ESPB) and Serratus Anterior Plane Block combined with Pectoral Nerve Block Type II (SAPB + PECS II) on intraoperative analgesia and…
- Conditions
- Pain Management in Breast Surgery, Pain After Surgery, Regional Anaesthesia
- Trial name
- NCT07368413
- Testing
- SAPB + PECS II Technique, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kayseri City Hospital
Cholecystectomy, Aromatherapy
The Effect of Aromatherapy in Laparoscopic Cholecystectomy Patients
Pain experienced before and after surgery in patients undergoing laparoscopic cholecystectomy adversely affects physiological parameters and sleep quality.
- Trial name
- NCT05464602
- Testing
- Intervention group Lavender, Intervention group Geranium
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- TC Erciyes University
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