Clinical trials: Post Polypectomy Bleeding
Gastrointestinal Bleeding
Uninterrupted Clopidogrel Therapy Before Elective Colonoscopy Will Increase the Risk of Post-polypectomy Bleeding
This double-blind, randomized trial aims to evaluate whether uninterrupted anti-platelet therapy (clopidogrel) will increase the risk of bleeding associated with removal of polyp during colonoscopy in patients with coronary…
- Trial name
- NCT01806090
- Testing
- clopidogrel
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Chinese University of Hong Kong
Post-polypectomy Bleeding, Colorectal Polyp
Argon Plasma Coagulation and Clip for the Prophylaxis of Post-polypectomy Bleeding After Hot Snare Polypectomy
Discuss the efficacy and safety of argon plasma coagulation （APC）in comparison with clip closure for preventing colorectal post-procedure bleeding（PPB） after hot snare polypectomy（HSP）; analyze the risk factors and the…
- Trial name
- APC、HSP (NCT05250518)
- Testing
- argon plasma coagulation, clip closure
- Where
- China
- Volunteers
- 1,017 people
- Sponsor
- Renmin Hospital of Wuhan University
Wound Endoscopical, Colon, After Polyp Resection, Colon
Efficacy of EndoClot™ Spraying After Endoscopic Resection of Large Colorectal Polyps
The effectiveness of colonoscopy in reducing colorectal cancer mortality relies on the detection and removal of neoplastic polyps.
- Trial name
- EndoClot™ (NCT05029934)
- Testing
- use of EndoClot
- Where
- 5 sites in Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Post-polypectomy Bleeding, Bowel Preparation
Effect of Inadequate Bowel Preparation on Urgent Colonoscopy in Patients With PPB.
The purpose of this study was to explore the effect of abbreviated bowel preparation on repeated colonoscopy in patients with PPB.
- Conditions
- Post-polypectomy Bleeding, Bowel Preparation, Urgent Colonoscopy
- Trial name
- PPB (NCT04468737)
- Testing
- Bowel preparation
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Ningbo No. 1 Hospital
Polyp of Large Intestine
EFficacy of Prophylactic Clip Application in Decrease of Immediate Postpolypectomy Bleeding and Delayed Postpolypectomy Bleeding After Colonoscopic Removal for a Large Pedunculated Polyps
The aim of this study is to evaluate the efficacy of prophylactic clip application after colonoscopic removal for a large pedunculated polyp (> 1cm) in preventing immediate postpolypectomy bleeding (IPPB) and delayed…
- Trial name
- NCT01437631
- Testing
- prophylactic clip application
- Where
- South Korea
- Volunteers
- 137 people
- Sponsor
- Asan Medical Center
Polyp Colorectal, Bleeding
Post Polypectomy Bleeding. Que Sera, Sera? Whatever Will be, Will be?
Patients with colorectal polyps removed endoscopically (polypectomy, endoscopic mucosal resection, underwater endoscopic mucosal resection, endoscopic submucosal dissection) may experience delayed post polypectomy bleeding.
- Trial name
- FILLIP (NCT06220149)
- Testing
- FIT (fecal immunochemical test)
- Where
- Romania
- Volunteers
- 200 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Gastrointestinal Hemorrhage
The Risk of Bleeding After Removal of Large Colorectal Polyps in Patients Taking Aspirin
The risk of bleeding after polypectomy of large colorectal polyps in patients taking aspirin is uncertain. This is a randomized, multi-center, placebo-controlled, double-blind study to compare the risk of significant bleeding…
- Trial name
- ASAPOL (NCT01549418)
- Testing
- Aspirin (ASA)
- Volunteers
- 760 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Colorectal Cancer
Evaluation of Nexpowder Application to Prevent Delayed Bleeding After Colorectal Endoscopic Mucosal Resection
Delayed bleeding is the most frequent (5 to 15%) and challenging complication after large colorectal polypectomy. Different preventive treatments, such as the prophylactic use of clips, have been tried to prevent the occurrence…
- Trial name
- NEXBLEED (NCT05247515)
- Testing
- Endoscopic mucosal resection with nexpowder
- Where
- France
- Volunteers
- 304 people
- Sponsor
- Gabriel RAHMI
Polyp Colorectal, Endoscopic Mucosal Resection
Structured TXI-RDI Integration for Endoscopic Resection
The goal of this clinical research study is to learn whether two advanced imaging tools, called Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), can make the removal of large colon polyps safer…
- Trial name
- STRIkER (NCT07474844)
- Testing
- Texture and Color Enhancement Imaging (TXI) and Red Dichromatic Imaging (RDI), High Definition White Light Endosocopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Delayed Post-Polypectomy Induced Ulcer Hemorrhage
Blood Flow Monitoring to Prevent Post-Polypectomy Induced Ulcer Bleeding
The primary specific aim is to perform a randomized controlled trial (RCT) to compare rates of delayed hemorrhage after DEP detection of arterial blood flow and focal treatment in PPIU's (treatment arm) with standard treatment…
- Trial name
- NCT02875353
- Testing
- Doppler Endoscopic Probe
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- VA Office of Research and Development
Polyp of Colon
Prevention of Post-Polypectomy Colorectal Bleeding by Clips in Patients on Anticoagulants
This observational study aims to retrospectively determine if clips can prevent post-polypectomy bleeding in adults who have received restarted anticoagulants after a colorectal polypectomy, using a large, single-center patient…
- Trial name
- PiCAnt (NCT07007598)
- Testing
- Hemostatic clip
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Helios Kliniken Schwerin
Post Polypectomy Bleeding
Safety of Cold Snare Polypectomy in Patients With Uninterrupted Antiplatelet Agent
Polypectomy is regarded as high risk for bleeding. Several guidelines recommend continuous use of aspirin during polypectomy. However for clopidogrel, widely used antiplatelet agent, cessation of 5-7 is recommended.
- Trial name
- NCT04328987
- Testing
- cold snare polypectomy
- Where
- South Korea
- Volunteers
- 314 people
- Sponsor
- Incheon St.Mary's Hospital
GastroIntestinal Bleeding
Effectiveness and Safety of Nexpowder as an Endoscopic Hemostatic Treatment
In patients who show signs of bleeding and bleeding after polypectomy such as EMR and ESD for polyps with a diameter of 2 cm or more in the lower gastrointestinal tract, the effectiveness and safety of Nexpowder as an endoscopic…
- Trial name
- NCT05884931
- Testing
- Nexpowder, Conventional Treatment
- Where
- 3 sites in South Korea
- Volunteers
- 66 people
- Sponsor
- Next Biomedical Co., Ltd.
Bleeding After GI Endoscopy
Prevention of Delayed Post-polypectomy Bleeding by Endoscopic Sucralfate Spray in High-risk Patients: A Randomized Controlled Trial
Background： Colonoscopy can detect colon polyps and perform excision to the polyps to prevent colon cancer. However, delayed polypectomy bleeding is one of the complications to be noticed, which has an occurrence rate of about…
- Trial name
- NCT07257926
- Testing
- Sucralfate, Clip
- Volunteers
- 160 people
- Sponsor
- National Cheng-Kung University Hospital
Procedural Bleeding, Delayed Bleeding
A Comparison of Eleview Versus Hetastarch as Injectate for EMR
EMR is a technique used for the removal of flat or sessile neoplasms confined to the superficial layers of the GI tract using a snare.
- Conditions
- Procedural Bleeding, Delayed Bleeding, Post-Polypectomy Syndrome, Post Procedural Complication
- Trial name
- NCT03350217
- Testing
- Eleview, Hetastarch
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Indiana University
Post Polypectomy Bleeding in Anticoagulated Patients, Gastrointestinal Hemorrhage
Hemorrhage Following Small Polyp Resection in the Colon in Anticoagulated Patients
One of the well-known of complications post colonic polypectomy is bleeding usually occuring in the 2-week period following the procedure. Patients treated with oral anticoagulation (e.g.
- Trial name
- NCT02375646
- Testing
- Warfarin, LMW Heparin
- Volunteers
- 286 people
- Sponsor
- Hadassah Medical Organization
Myocardial Infarction (MI), Cardiovascular Events
Aspirin Continuation or Interruption in Patients at Moderate Risk for Cardiovascular Events Undergoing Colonoscopy and/or Polypectomy
One in 4 adults between 50 and 80 reports taking regular aspirin. The prevalence of aspirin uses increases with age as well as co-morbid vascular diseases.
- Conditions
- Myocardial Infarction (MI), Cardiovascular Events, Post Polypectomy Bleeding in Antiplatelet Patients
- Trial name
- NCT07052799
- Testing
- Aspirin 80mg
- Where
- Hong Kong
- Volunteers
- 2,514 people
- Sponsor
- Chinese University of Hong Kong
Post Polypectomy Bleeding
A Trial on Prophylactic Clipping to Prevent Post-polypectomy Bleeding After Colonoscopy in Direct Oral Anticoagulant Users
The investigators hypothesize that prophylactic clipping after colonoscopic polypectomy can reduce risk of delayed PPB among DOAC users.
- Trial name
- PROCLIP (NCT05169242)
- Testing
- Endoclip
- Where
- Hong Kong
- Volunteers
- 584 people
- Sponsor
- Chinese University of Hong Kong
Post-polypectomy Bleeding, Polypectomy
Risk of Post-polypectomy Bleeding With Prophylactic Hemoclipping
A randomized trial aimed at determining whether or not hemoclips are effective in preventing post-polypectomy bleeds on polyps that are 10mm in size or greater.
- Conditions
- Post-polypectomy Bleeding, Polypectomy, Elective Colonoscopy
- Trial name
- NCT01647581
- Testing
- Hemoclip Placement, NO hemoclip placement
- Where
- 3 sites in United States
- Volunteers
- 11,182 people
- Sponsor
- VA Office of Research and Development
Liver Cirrhosis, Portal Hypertension Related to Cirrhosis
Colonic Polypectomy in Cirrhotic Patients With Portal Hypertension
The goal of this retrospective cohort study is to evaluate the risk of post-polypectomy bleeding following the colonoscopy resection of lower gastrointestinal polyps in patients with liver cirrhosis with portal hypertension.
- Conditions
- Liver Cirrhosis, Portal Hypertension Related to Cirrhosis, Polyp of Colon, Polypectomy
- Trial name
- NCT06832826
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University