Clinical trials: Post Prostatectomy
Urinary Incontinence
Effects of External Electrical Stimulating Applied on the Thigh in Men With Urinary Incontinence After Prostatectomy
The aim of this study is to investigate the effects of external electrical stimulation applied on the thigh on urinary symptoms, quality of life, sexual function, perception of subjective improvement and satisfaction in men with…
- Trial name
- NCT05432869
- Testing
- ES and lifestyle advices, Lifestyle advices
- Volunteers
- 40 people
- Sponsor
- Ankara Yildirim Beyazıt University
Erectile Dysfunction
Low Intensity Shock Wave Therapy in the Rehabilitation Treatment of Erectile Dysfunction After Robotic Radical Prostatectomy.
The study deals with the hypothesis that LiESWT in addition to the administration of PDE5i can improve sexuality rehabilitation with faster recovery of a valid erection and higher IIEF-5 scores in the short and medium-term…
- Trial name
- NCT06442020
- Testing
- Tadalafil (PDE5i)
- Where
- Italy
- Volunteers
- 158 people
- Sponsor
- Regina Elena Cancer Institute
Prostate Cancer
Radiation Therapy With or Without Bicalutamide for Recurrent pT3N0 Prostate Cancer After Radical Prostatectomy
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Androgens can stimulate the growth of prostate cancer cells.
- Trial name
- NCT00002874
- Testing
- bicalutamide, radiation therapy
- Where
- 240 sites in United States, Canada
- Volunteers
- 840 people
- Sponsor
- Radiation Therapy Oncology Group
Prostatic Neoplasms, ctDNA
Prognostic Study of Via Dynamic Change of dT-DNA in Drainage Fluid After Radical Prostatectomy
This study investigates the prognostic value of dynamic changes in Drainage Tumor DNA(dT-DNA) levels found in the peritoneal drainage fluid after radical prostatectomy.
- Trial name
- NCT06707974
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Stress Urinary Incontinence
A Post-Market Study of the AMS AdVance™ Male Sling System for the Treatment of Male Stress Urinary Incontinence
A prospective, multi-center study of the AdVance Male Sling for Stress Urinary Incontinence. The purpose of this study is to obtain surgical technique data for use in physician education and training and to collect early clinical…
- Trial name
- NCT00998790
- Testing
- American Medical Systems (AMS) AdVance™ Male Sling System
- Where
- 3 sites in Belgium, France
- Volunteers
- 114 people
- Sponsor
- Boston Scientific Corporation
Electrical Stimulation
Electrical Stimulation in Men With Urinary Incontinence After Radical Prostatectomy
Aim: In this study, the investigators aimed to assess the efficacy of perineal electrical stimulation on anxiety, depression, quality of life (QOL), and clinical parameters associated with incontinence in men with urinary…
- Trial name
- NCT05236140
- Testing
- Perineal electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Overactive Bladder, Benign Prostate Hyperplasia
Post Marketing Study to Evaluate the Efficacy and Safety of Solifenacin in Patients With OAB (Overactive Bladder) After TURP (Trans-urethral Resection of Prostate) or PVP (Photoselective Vaporization of Prostate)
The purpose of this study is to demonstrate superiority of the solifenacin succinate (treatment) over the placebo (control) based on the change from the baseline in the mean number of urgency episodes per 24 hours after 2 weeks.
- Conditions
- Overactive Bladder, Benign Prostate Hyperplasia, Transurethral Resection of Prostate, Photoselective Vaporization Prostatectomy
- Trial name
- POST-TURP (NCT01747577)
- Testing
- Solifenacin Succinate
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Astellas Pharma Korea, Inc.
Prostate Cancer, Quality of Life
Enhanced Recovery Program After a Robotic-assisted Surgery (RAAC) of Radical Prostatectomy. PROSTA-RAAC
There are few published data on the benefit of Enhanced recovery program in radical prostatectomy in the management of localized prostate cancer. All the studies available on the subject are retrospective (1-3).
- Conditions
- Prostate Cancer, Quality of Life, Recovery Programm
- Trial name
- PROSTA-RAAC (NCT05172986)
- Testing
- Follow-up patient program
- Where
- France
- Volunteers
- 135 people
- Sponsor
- Elsan
Prostate Cancer, Bladder Cancer
Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy
Laparoscopic and minimally-invasive robotic access has transformed the delivery of urological surgery. While associated with numerous desirable outcomes including shorter post-operative stay and faster return to preoperative…
- Conditions
- Prostate Cancer, Bladder Cancer, Surgery, Renal Impairment
- Trial name
- NCT06408597
- Testing
- Nitroglycerin Infusion, Mannitol Infusion, Fluid Regimen
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Nazmy Edward Seif
Prostate Cancer
Long-term Better Than Short-term ADT With Salvage RT
A randomized, multicenter, prospective PHASE II trial to assess the effect of short- versus long-term adjuvant ADT with high dose salvage radiotherapy on distant metastasis free survival in case of biochemical relapse (BR) after…
- Trial name
- LOBSTER (NCT04242017)
- Testing
- Triptoreline
- Where
- 3 sites in Belgium
- Volunteers
- 394 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pain, Postoperative
Spinal Morphine for Postoperative Analgesia in Urology
The study was performed in urology patients elicited for open prostatectomy or open nephrectomy. Comparison of analgesic effect between group (M) with spinal morphine before general anaesthesia and group without this intervention…
- Trial name
- NCT03675646
- Testing
- Morphine
- Where
- Czechia
- Volunteers
- 98 people
- Sponsor
- Charles University, Czech Republic
Postoperative Cognitive Dysfunction
S100B Protein and Postoperative Cognitive Dysfunction
Primary aim of this study is to evaluate the association between postoperative cognitive dysfunction and increased serum levels of S100B protein after robot-assisted laparoscopic radical prostatectomy.
- Trial name
- NCT03018522
- Testing
- Postoperative cognitive dysfunction
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Antalya Training and Research Hospital
Post Radical Prostatectomy Urinary Incontinence
Efficacy of Extracorporeal Magnetic Stimulation, Pelvic Floor Muscle Exercise, and Combination of Both in Management of Post Radical Prostatectomy Urinary Incontinence
Urinary incontinence is one of the most common complications of radical prostatectomy. Multiple prevention and treatment modalities have been proposed in the management of post prostatectomy urinary incontinence.
- Trial name
- NCT05680168
- Testing
- Extracorporeal electromagnetic stimulation, Pelvic floor exercises
- Where
- Qatar
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hamad General Hospital
Prostate Cancer With Radical Prostatectomy
The Efficacy and Safety of Udenafil in Patients With Erectile Dysfunction After Bilateral Nerve-sparing Radical Prostatectomy
This study evaluates the efficacy and safety of Udenafil dosed once a day in patients with erectile dysfunction after bilateral nerve-sparing radical prostatectomy.
- Trial name
- DA8159_EDP_IIT (NCT03142542)
- Testing
- ZYDENA TAB.75mg(Udenafil 75mg)
- Volunteers
- 99 people
- Sponsor
- Samsung Medical Center
Prostate Cancer
Ga-68 PSMA-11 PET/CT in Patients With Biochemical Recurrence of Prostate Cancer: Digital PET/CT Versus Analog PET/CT
Ga-68 PSMA-11 PET/CT is known as useful method for localizing recurred tumor lesions in prostate cancer patients with biochemical recurrence [elevated serum prostate specific antigen (PSA) after radical prostatectomy].
- Trial name
- NCT04846894
- Testing
- Ga-68 PSMA-11 PET/CT imaging
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Jin-Sook Ryu
Prostate Cancer (Post Prostatectomy), Urinary Incontinence
Effects of Hypopressive Exercises on Urinary Incontinence and Erectile Dysfunction After Radical Prostatectomy
This randomized controlled trial investigates the effects of hypopressive exercises on urinary incontinence and erectile dysfunction in men following radical prostatectomy.
- Conditions
- Prostate Cancer (Post Prostatectomy), Urinary Incontinence, Erectile Dysfunction Following Radical Prostatectomy, Pelvic Floor Muscle Training
- Trial name
- NCT07101731
- Testing
- Pelvic Floor Muscle Training (PFMT), Hypopressive Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bartın Unıversity
Prostate Cancer, Urinary Incontinence
Prospective RCT on Post Prostatectomy Urine Leak
Objectives: Primary: Comparison of proportion of patient achieving continence between the four arms at 6 months. Secondary: Comparison of time to achieve continence between the four arms.
- Trial name
- NCT02367404
- Testing
- Duloxetine, Pelvic Floor Muscle Training
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Institut Mutualiste Montsouris
Prostatic Hyperplasia
Functional Changes of Urogenital System After Holmium Laser Prostatectomy
Holmium laser prostatectomy will enhance voiding function. Holmium laser prostatectomy will enhance sleep quality. Holmium laser prostatectomy will enhance renal function.
- Trial name
- NCT02033785
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- The Catholic University of Korea
Prostate Cancer (Post Prostatectomy), Prostate Cancer
RIsk aDapted Stereotactic Radiotherapy vs. standarD of Care Radiotherapy in Patients With Prostate Cancer in the Adjuvant or saLvage sEtting With or Without Lymph Node Irradiation (RIDDLELN) - A Phase III Trial
The goal of this clinical trial is to determine whether stereotactic body radiotherapy (SBRT) delivered in five fractions is non-inferior to standard-of-care mildly hypofractionated radiotherapy in terms of patient-reported…
- Conditions
- Prostate Cancer (Post Prostatectomy), Prostate Cancer, SBRT
- Trial name
- RIDDLELN (NCT07830511)
- Testing
- Stereotactic body radiotherapy (SBRT) to the prostate bed, Standard-of-care radiotherapy (SOC) to the prostate bed
- Volunteers
- 206 people
- Sponsor
- Robert Förster
Prostatic Neoplasm
Determination of the Diagnostic Detection Rate of Axumin (Fluciclovine) Digital PET/CT, Post-prostatectomy
Fluciclovine F18 (Axumin) has been demonstrated to provide good delineation of recurrence of prostate cancer after definitive therapies.
- Trial name
- NCT04234399
- Testing
- Fluciclovine PET/CT using a digital PET/CT
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Vermont