Clinical trials: Post Stroke
Cerebrovascular Accident
Oxygen Consumption in Post-stroke Patients During Various Walking Activities Compared to Healthy Controls
Stroke is major public health issue. The investigators recommend post-stroke patients to practice physical activity. Nevertheless, the recommendations are not widely respected due to the intensity of exercises.
- Trial name
- STROXCO (NCT05477238)
- Testing
- walking tasks
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Stroke
Development and Evaluation of iWalk: A Guide to Facilitate Evidence-informed Assessment of Walking After Stroke
Stroke remains a major health concern and the second highest cause of disability worldwide. After experiencing a stroke, many people lose the ability to walk independently.
- Trial name
- NCT04184843
- Testing
- iWalk Toolkit
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stroke, Healthy
Cerebral Hemodynamics During Early Verticalization After (Successful) Thrombectomy Poststroke
This is a proof-of-concept study with a prospective observational design, where the association between progressive levels of verticalization and cerebral blood flow velocity (Ultrasound) in subacute stroke patients and healthy…
- Trial name
- CHEST (NCT04573114)
- Testing
- Verticalization
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Stroke
Aha BOOST Arm-hand BOOST Therapy to Enhance Recovery After Stroke: Clinical, Health Economic and Process Evaluation
The overall aim of this study is to establish the clinical- and cost-effectiveness of the arm-hand BOOST therapy when delivered on top of the usual care program in the sub-acute phase post stroke and to perform a process…
- Trial name
- AHA-BOOST (NCT06517251)
- Testing
- Arm-hand BOOST, Lower limb BOOST
- Where
- 2 sites in Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Stroke
Premotor Cortex: A New Target for Stroke Motor Rehabilitation
The goal of the study is to determine the effect of repetitive transcranial magnetic stimulation (rTMS) over the premotor cortex on training-related improvements in motor performance and associated neural plasticity.
- Trial name
- NCT02565199
- Testing
- rTMS Over Contralateral Hemisphere of Premotor Cortex, rTMS Over Ipsilateral Hemisphere of Premotor Cortex, Control 1: rTMS Timed 400 ms After Movement-related EMG
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke Osteoporosis
Assesment and Comparison of Osteoporosis Risk Factors After Stroke
The aim of this study is to evaluate the effect of these factors and stroke itself on osteoporosis developing after stroke. Thus, the expected benefit of the study is to contribute to the identification and determination of the…
- Trial name
- NCT07228611
- Testing
- Bone Mineral Density
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Healthy Subjects or Volunteers, Chronic Stroke
Investigating the Impact of Afferent Stimulation on Proprioceptive Function in Post-Stroke Rehabilitation
The objective of this study is to assess the functionality of a sensory stimulation device that uses mechanical vibrations and low-intensity electrical currents to deliver proprioceptive feedback to stroke patients regarding…
- Trial name
- NCT07073989
- Testing
- Afferent stimulation
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Julio S. Lora Millán
Stroke
The Effect of Optic Flow Speed Manipulation and the Level of Immersion on the Gait Pattern in People Post-stroke
The aim of this study is to investigate the effect of manipulating the optic flow speed in the virtual environment on the gait pattern during virtual reality (VR) - enhanced treadmill walking in people post-stroke.
- Trial name
- NCT04521829
- Testing
- Walking with different optic flow speeds with 2 different VR devices
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Stroke
Robot Aided Rehabilitation - Multi-joint Evaluations
Sensory and motor impairments following stroke can lead to substantial disability involving the arm and hand. The investigator hypothesized that excessive local and cross-coupled stiffness, diminished individuation and…
- Trial name
- Aim1 (NCT02359812)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
CVA, Gait, Hemiplegic
Robotic Exoskeleton Assisted Gait Post Stroke
The current investigation takes advantage of both a progressive and adaptive assist-as-needed massed practice and time-sensitive neuroplasticity through exoskeleton assisted walking in order to induce greater recovery-oriented…
- Trial name
- RE-Assist (NCT04309305)
- Testing
- EksoGT™, Ekso Bionics, Berkley, CA, USA, Standard of Care, No Intervention
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Stroke, Acute, Neuroprotection
Effectiveness and Biological Mechanism of Direct Ischemic Post-conditioning for Acute Stroke Patients Due to Large Vessel Occlusion
The goal of this clinical trial is to determine if direct ischemic post-conditioning (IPostC) can alleviate ischemic-reperfusion injury (I/R) in patients who have undergone endovascular thrombectomy (EVT).
- Conditions
- Stroke, Acute, Neuroprotection, Ischemic Conditioning
- Trial name
- NCT06545734
- Testing
- Direct Ischemic Post-conditioning, Endovascular therapy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tianjin Huanhu Hospital
Stroke, Depression
Testing a Positive Psychology-based Intervention for Couples Coping With Stroke
This study aims to pilot test an 8-week, self-administered dyadic (couples-based) positive psychology intervention for couples coping with stroke using a randomized, waitlist control design.
- Conditions
- Stroke, Depression, Depressive Symptoms, Post-stroke Depression
- Trial name
- RESToreD (NCT03335358)
- Testing
- Dyadic (couples-based) positive psychology intervention
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Utah
Stroke, Spasticity, Muscle
Individualized rTMS Based on fNIRS to Spasticity
Stroke is of high morbidity and mortality, and surviving patients are often unable to take care of themselves because of severe motor dysfunction.
- Conditions
- Stroke, Spasticity, Muscle, Rehabilitation
- Trial name
- NCT05318586
- Testing
- individual rTMS based on fNIRS, Traditional rTMS strategy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Stroke, Ischemic, Hemianopia, Homonymous
Statistical Learning as a Novel Intervention for Cortical Blindness
This project aims to develop a novel visual training paradigm for use in visually-intact participants and those sufferings from stroke-induced visual impairments.
- Conditions
- Stroke, Ischemic, Hemianopia, Homonymous, Hemianopsia, Occipital Lobe Infarct
- Trial name
- NCT06578117
- Testing
- Vision Training and Learning Task
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Stroke
Control of Degrees of Freedom Post-stroke for the Recovery of the Upper Limb
The study's methodology will be a single-blind, multicenter, parallel-group randomized controlled trial (RCT). The sample consists of stroke patients (supratentorial ischemic and hemorrhagic stroke of anterior territory) between…
- Trial name
- DoF_UL_S (NCT05371444)
- Testing
- Training with restriction of the DoF, Training without restriction of the DoF
- Where
- Chile
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Chile
Stroke
Characterizing the Neural Bases of Motivational Disorders After Stroke
The aim of the study is to quantify elementary mechanisms of motivation, with innovative tools adapted to clinical settings, in healthy subjects, and in stroke patients.
- Trial name
- MOTI-stroke (NCT03741140)
- Testing
- Motivation tests
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Stroke
Hybrid Brain Computer Interface for Control of Sensory - Motor Coupling in Post - Stroke Rehabilitation
HYBIS project aims to develop an innovative and unique hybrid Brain-Computer Interface (BCI) system. This BCI system is envisioned as a novel tool for targeted reinforcement of sensory motor coupling, specifically dedicated for…
- Trial name
- HYBIS (NCT05152108)
- Testing
- BCI feasibility test
- Where
- Serbia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Stroke
SH-SS and GSH-GSSG Homeostasis in Post-stroke Patients
In patients undergoing physical therapy after stroke, extracellular thiol-disulfide balance and intracellular oxidized-reduced glutathione balance levels will be monitored.
- Trial name
- NCT04884555
- Testing
- Standard neurorehabilitation, Thiol-Disulphide Homeostasis, Oxidized-reduced Glutathione Homeostasis
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Cerebrovascular Accident
Role of the Intact Hemisphere in Recovery of Motor Function After Stroke
The purpose of this study is to better understand the role of the motor part of the brain in the recovery of motor function after stroke. The motor deficits that follow a stroke are compensated for over several months.
- Trial name
- NCT00028184
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)