Clinical trials: Post Stroke
Healthy Subjects or Volunteers, Chronic Stroke
Investigating the Impact of Afferent Stimulation on Proprioceptive Function in Post-Stroke Rehabilitation
The objective of this study is to assess the functionality of a sensory stimulation device that uses mechanical vibrations and low-intensity electrical currents to deliver proprioceptive feedback to stroke patients regarding…
- Trial name
- NCT07073989
- Testing
- Afferent stimulation
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Julio S. Lora Millán
Post-stroke Depression, Healthy
Effects and Central Mechanism of Electroacupuncture and MRI-navigated rTMS for PSD
Introduction: Post-stroke depression (PSD) is the most common mental complication after stroke and has a serious impact on functional outcomes and quality of life.
- Trial name
- NCT05516680
- Testing
- electro-acupuncture, MRI-navigated rTMS
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Acute Ischemic Stroke
Predictive Study of Serum Endocan for Hemorrhagic Transformation After Reperfusion Therapies in Acute Ischemic Stroke
Stroke is the second largest cause of death globally after ischemic heart disease.Of the total number of prevalent strokes, 84.4% are ischemic.
- Trial name
- NCT05228080
- Testing
- enzyme-linked immunosorbent assay(ELISA)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Aphasia, Stroke
Adapted Solution Focused Therapy for People With Aphasia (SOFIA Trial)
Around one third of stroke survivors will have aphasia, which means they will have difficulty talking, understanding, reading or writing.
- Trial name
- SOFIA (NCT03245060)
- Testing
- Adapted Solution Focused Brief Therapy
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- City, University of London
Stroke
Non-Invasive Brain Signal Training to Induce Motor Control Recovery After Stroke
The purpose of this trial was to evaluate the benefits of combination motor learning training and brain computer interface training for restoring arm function in people with stroke.
- Trial name
- NCT00746525
- Testing
- Surface functional electrical stimulation (FES), Motor learning, Brain computer interface (BCI) training
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Louis Stokes VA Medical Center
Stroke, Healthy Health Care Professionals
Usability and Acceptability Study of a Functional Electro-stimulator Controlled by Electromyographic Signal (FitFES)
Functional recovery of the upper limb after a cerebral stroke is one of the major critical issues in rehabilitation. The advent of innovative technologies can be helpful to rehabilitators and intervene where there is no other…
- Trial name
- NCT06763874
- Testing
- EMG-based FES device
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Gait Disorders, Neurologic
Dynamic Ultrasound of the Calf Muscles After Stroke
Muscle behaviour of calf muscles can be studied during dynamic conditions using dynamic ultrasound. In particular, the medial gastrocnemius is suitable for measurements with dynamic ultrasound due to its superficial location.
- Trial name
- Stroke_DynUS (NCT06250478)
- Testing
- Dynamic ultrasound of the calf muscles
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Gait, Hemiplegic
Lower Body Positive Pressure Treadmill Training in Post-Stroke Gait Impairment
Lower body positive pressure (LBPP) decreases weight bearing and ground reaction forces, with potentially positive effects on qualitative gait indices.
- Trial name
- NCT03957785
- Testing
- AlterG Treatment
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Spatial Neglect, Stroke
Spatial-Motor Stroke-Rehab Study
The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.
- Trial name
- NCT06053320
- Testing
- Prism adaptation therapy (PAT) + Electrical stimulation (E-stim), Gait Training
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Emory University
Traumatic Brain Injury, Cerebral Infarction
Characteristics of Blood- Brain Barrier Permeability in Neurological Patients
The main goal of the present study is to challenge the hypothesis that blood- brain barrier disruption following brain injury increases the risk for long-term disability, development of brain dysfunction, epileptic seizures and…
- Conditions
- Traumatic Brain Injury, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- NCT00419874
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Acute Ischemic Stroke, Cerebral Edema
The Tolerability, Safety, and PK Characteristics of SIM1910-09 in Healthy Chinese Volunteers
This is a single-center, randomized, double-blind, placebo-controlled Phase I clinical study to evaluate the tolerability, safety, and pharmacokinetic characteristics of SIM1910-09 for injection after single/multiple dosing in…
- Trial name
- NCT05200728
- Testing
- SIM1910-09
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Stroke
Validation Study of SCALA, Scale for Lateropulsion
Development and clinical validation of SCALA, a new rating scale for lateropulsion after stroke. A monocentric clinical study including 78 post-stroke individuals and 30 patients without stroke and/or healthy volunteers.
- Trial name
- SCALA (NCT03077399)
- Testing
- SCALA
- Where
- France
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Stroke, Sensorimotor Impairment
Learning in Stroke
After a stroke, plasticity occurs in the brain from microscopic to network level with positive but also negative consequences for functional recovery.
- Trial name
- NCT05511467
- Testing
- Visuomotor learning task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Stroke, Healthy Adult
Tracking Post-stroke Walking Improvements From the Clinic Into the Home
The purpose of this proposal is to use novel video-based movement tracking technology to measure gait quality after stroke - in the home.
- Trial name
- NCT05454007
- Testing
- Step length asymmetry training
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Stroke, Cerebro-vascular Accident
Upper Arm Reahabilitation After Stroke and Video Game
The purpose of this study is to assess the efficiency of occupational therapy enhanced by "dedicated adaptative video games" in rehabilitation of the upper arm of stroke patients in the acute phase after their cerebro-vascular…
- Conditions
- Stroke, Cerebro-vascular Accident, Upper Arm Disability, Reaching
- Trial name
- MARGAUT (NCT01554449)
- Testing
- serious game reeducation, functional MRI
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cerebrovascular Stroke
Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke
The purpose of this study is to examine how different areas in the brain interact with each other and how using brain imaging and brain stimulation approaches can influence these interactions.
- Trial name
- NCT02465034
- Testing
- Transcranial Magnetic Stimulation, Traditional Paired Associative Stimulation, Median Nerve Stimulation
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Emory University
COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction
COVID-19 Vaccination Detoxification in LDL-C
The study hypothesizes that SARS-CoV-2 vaccination poisoning hibernates in human host in Low Density Lipoprotein Cholesterol (LDL-C). The clinical trial is a follow-up from the intervention trial with NCT number NCT05711810.
- Conditions
- COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction, COVID-19-Associated Thromboembolism, COVID-19 Post-Intensive Care Syndrome
- Trial name
- NCT05839236
- Testing
- Atorvastatin Calcium Tablets
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yang I. Pachankis
Right Hemisphere Stroke
Prosody Assessment After Right Hemisphere Stroke
Following a right stroke, more than half of the patients present a communication disorder. These disorders can notably concern prosody. Nevertheless, these remain relatively poorly assessed and characterized.
- Trial name
- ProsAVC (NCT05874011)
- Testing
- understanding of prosody
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aphasia, Language
tDCS as an Adjuvant to Intensive Speech Therapy for Chronic Post Stroke Aphasia
The purpose of this study is to determine if transcranial direct current stimulation (tDCS) in conjunction with intensive speech therapy will improve sentence production and word retrieval in individuals with chronic post stroke…
- Trial name
- NCT02801864
- Testing
- Real tDCS, Intensive Speech Therapy
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Austin Speech Labs
Stroke
The Autonomic Nervous System State and Response to Different Stimuli Among Patients Post Stroke: A Follow-up Study
The study describes the autonomic control system function in subjects post stroke in comparison with healthy subjects. Aims: To describe the Autonomic hart rate control system function in post stroke subjects in different…
- Trial name
- NCT01632410
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center