Clinical trials: Post Stroke
Stroke, Upper Extremity Paresis
Post-stroke Haptic Feedback Use Deficit: A Comparative and Reliability Study
The aim of this comparative and reliability study is to highlight a deficit in the use of vibrotactile sensory feedback (haptic effect) in the planning and execution of fine manual dexterity movements after stroke.
- Conditions
- Stroke, Upper Extremity Paresis, Manual Dexterity, Sensory Integration Dysfunction
- Trial name
- HapticS (NCT06344221)
- Testing
- Dextrain Manipulandum and haptic feedback device
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Stroke, Post-stroke Hemiparesis
Operant Conditioning of Reflex Pathways to Improve Walking in Individuals Post-stroke
The purpose of this study is to examine the changes in reflex pathways in the paretic ankle plantarflexors in individuals with post-stroke hemiparesis using operant conditioning.
- Conditions
- Stroke, Post-stroke Hemiparesis, Foot Drop
- Trial name
- NCT05801744
- Testing
- Operant conditioning
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Stroke, Psychological Well-Being
Aspirational Rehabilitation Coaching for Holistic Health (ARCH): A Pilot Pre-Post Experimental Study
The ARCH programme is a novel, strength-based, dyadic, multicomponent psychosocial intervention that blends together psychoeducation, psychosocial support and self-compassion practices to aid first-time stroke survivors and their…
- Conditions
- Stroke, Psychological Well-Being, Psychosocial Functioning
- Trial name
- NCT06596551
- Testing
- Pre-Post ARCH Intervention
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Stroke
Skeletal Muscle Properties and the Metabolic Cost of Walking Post-stroke
Of the ~700,000 persons who suffer a stroke each year, only 50% recover the ability to perform unlimited community walking. One mechanism contributing to locomotor dysfunction post-stroke is an increased metabolic cost of walking…
- Trial name
- NCT00721357
- Testing
- Treadmill walking, Magnetic resonance spectroscopy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Upper Limb Robotic Rehabilitation After Stroke
This is a single arm study aimed at evaluating the acute effects induced by a single session of robot-assisted passive hand mobilization on local perfusion and upper limb function in post-stroke hemiparetic patients.
- Trial name
- NCT03243123
- Testing
- Robotic passive mobilization
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Brescia
Cerebral Apoplexy
Single-dose Incremental Intravenous Injection of SY-007 in Healthy Subjects
This study is a single-dose incremental, randomized, double-blind, parallel, placebo-controlled study on safety, tolerance and pharmacokinetics healthy subjects.
- Trial name
- NCT04111523
- Testing
- SY-007
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Suzhou Yabao Pharmaceutical R&D Co., Ltd.
Stroke
Myoelectric Robot-assisted Rehabilitation for the Upper Limb After Stroke
The aim of this study is to assess the clinical effectiveness of the RehaARM-robot and to determine the feasibility of including robotic therapy in daily rehabilitation programmes, after stroke.
- Trial name
- MyoReArm (NCT02321254)
- Testing
- The RehaARM-Robot, Standard rehabilitation therapy
- Where
- 2 sites in Austria, Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Stroke, Hemiparesis After Stroke
Optimizing Cortical Priming
Each year over 795,000 people suffer from stroke resulting in the primary cause of adult disability. Persistent upper limb dysfunction due to stroke significantly impairs performance and results in a serious decline of quality of…
- Trial name
- NCT07860073
- Testing
- 5 Hz Repetitive transcranial magnetic stimulation (rTMS) on the contralesional dorsal premotor cortex (cPMd), 5 Hz Repetitive transcranial magnetic stimulation (rTMS) on the ipsilesional primary motor cortex (iM1)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wan-Wen Liao
Stroke
Individualized Magnetic Stimulation for Post-stroke Cognitive Recovery: Optimization, Validation & Efficacy
Rationale: 75% of all stroke survivors suffer from cognitive deficits in the acute phase, with serious implications for their long-term quality of life and societal participation.
- Trial name
- IMPROVE (NCT07150169)
- Testing
- Active TMS disruption
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Jord Vink
Stroke
Meditation and Biofeedback to Improve Anxiety, Depression and Quality of Life in Inpatients After Stroke
The goal of this clinical trial is to investigate the impact of a technology-based meditation program in the inpatient stroke population.
- Trial name
- NCT05845541
- Testing
- Technology Supported Meditation and Biofeedback, Standard Treatment
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Ischemic Stroke, Upper Limb Motor Impairment
Neurophysiological Markers for Prediction of Rehabilitation Outcomes After Ischemic Stroke
The goal of this randomized controlled study is to develop and validate an integrated neurophysiological model for predicting rehabilitation potential in patients with ischemic stroke.
- Trial name
- NCT07520630
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Shoulder Subluxation After Stroke
Effective Treatment of Shoulder Subluxation After Stroke With Modified Acupuncture of Biceps Brachii Muscle, Supraspinatus Muscle and Deltoid Muscle
Stroke is the most common emergency in neurology and is also the leading cause of disability, so recovery of movement after stroke is very important.
- Trial name
- NCT06545357
- Testing
- Acupuncture
- Where
- Vietnam
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Stroke, Cerebro-vascular Accident
Studying Fatigue and Movement After Stroke
The goal of this observational study is to learn how neuromuscular fatigue develops after stroke and how changes in brain activity, muscle activity, and their interaction contribute to reduced motor performance in stroke…
- Conditions
- Stroke, Cerebro-vascular Accident, Ischemia Stroke, Hemorrhage Stroke
- Trial name
- NCT07594938
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Stroke
SH-SS and GSH-GSSG Homeostasis in Post-stroke Patients
In patients undergoing physical therapy after stroke, extracellular thiol-disulfide balance and intracellular oxidized-reduced glutathione balance levels will be monitored.
- Trial name
- NCT04884555
- Testing
- Standard neurorehabilitation, Thiol-Disulphide Homeostasis, Oxidized-reduced Glutathione Homeostasis
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Cerebrovascular Accident
Role of the Intact Hemisphere in Recovery of Motor Function After Stroke
The purpose of this study is to better understand the role of the motor part of the brain in the recovery of motor function after stroke. The motor deficits that follow a stroke are compensated for over several months.
- Trial name
- NCT00028184
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Delayed Cerebral Ischemia After Subarachnoid Hemorrhage, Ischemic Stroke of Large or Medium Vessels
Thrombo-inflammation in Acute Neurovascular Diseases: Definition of New Therapeutic Targets (TARGETS)
The objective of this observational study is to compare the relative concentrations of various thrombo-inflammatory markers at different follow-up time points in: patients with or without delayed cerebral ischemia after…
- Trial name
- NCT07354321
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- François Delvoye
Stroke
Gait Training in Post-Stroke Hemiparesis Hemiparesis
The focus of this study is to optimize the delivery of a combined strength and aerobic training regimen to individuals with post stroke hemiparesis and reduce overuse and inefficiencies associated with the nonparetic leg during…
- Trial name
- NCT04877249
- Testing
- Split-belt treadmill training
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Stroke, Ischemic, Quadrantanopia
Vision Loss Impact on Navigation in Virtual Reality
The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving.
- Conditions
- Stroke, Ischemic, Quadrantanopia, Hemianopsia, Homonymous, Hemianopia, Homonymous
- Trial name
- NCT06047717
- Testing
- Virtual Reality Driving Task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Central Post-stroke Pain
Structural and Functional Grey and White Matter Changes in Patients With Pain Disorders
The goal of this observational study is to examine the association between exact lesion location and presence of thalamic CPSP (Central post-stroke pain) in a larger number of patients after thalamic stroke.
- Trial name
- NCT05679297
- Testing
- Quantitative sensory testing (QST), Magnetic resonance imaging (MRI), Clinical interview/exam
- Where
- Switzerland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postoperative Cognitive Dysfunction, Cerebrovascular Accident
Neurological Outcome After Minimal Invasive Coronary Artery Bypass Graft
Primary objectives: Assessment of the incidence of postoperative cognitive dysfunction (POCD), cerebrovascular accident (CVA), and delirium after minimal invasive coronary artery bypass grafting (Endo-CABG).
- Conditions
- Postoperative Cognitive Dysfunction, Cerebrovascular Accident, Delirium
- Trial name
- NOMICS (NCT02979782)
- Testing
- Endo-CABG, PCI
- Where
- 2 sites in Belgium
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital