Clinical trials: Post Stroke Pain, open to volunteers
Stroke
Myofascial Dysfunction in Post Stroke Shoulder Pain
Shoulder pain is extremely common after stroke and occurs in 30-70% of patients. The pain may begin as early as one week after stroke, although peak onset and severity occurs around four months, and persists into the chronic…
- Trial name
- NCT06718413
- Testing
- hyaluronidase plus saline, saline
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Johns Hopkins University
Hemiplegic Shoulder Pain
Effectiveness of High-intensity Peripheral Magnetic Stimulation on Hemiplegic Shoulder Pain After Stroke
This study aims to investigate the effectiveness of high-intensity electromagnetic stimulation using the BTL-6000 Super Inductive System (SIS) in the management of hemiplegic shoulder pain in patients with stroke.
- Trial name
- NCT07912138
- Testing
- Active Peripheral Magnetic Stimulation
- Volunteers
- 30 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Hemiplegia, Stroke
The Effect of Shoulder Problems on Balance in Hemiplegic Patients
Shoulder problems are among the most common complications in hemiplegic patients and may impair shoulder biomechanics, negatively affecting mobility, transfers, and self-care.
- Trial name
- NCT07159178
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Aydın University
Central Post-stroke Pain, Stroke
Motor Cortex Stimulation for Post-Stroke Thalamic Pain
The goal of this clinical trial is to investigate the mechanisms and predictive factors of motor cortex stimulation (MCS) for treating post-stroke thalamic pain, a challenging central neuropathic pain condition.
- Conditions
- Central Post-stroke Pain, Stroke, Electric Stimulation Therapy, Multimodal Imaging
- Trial name
- NCT07758829
- Testing
- Motor Cortex Stimulation (MCS) System
- Volunteers
- 200 people
- Sponsor
- Aerospace Center Hospital
Chronic Pain, Stroke
VR-ACT After Stroke: a Feasibility Study
This exploratory project aims to develop and pilot test, in a parallel group randomized controlled trial (RCT) design, the feasibility, acceptability, and preliminary efficacy of a self-management virtual reality (VR) 8-week…
- Trial name
- VR-ACT (NCT06990646)
- Testing
- VR-ACT
- Volunteers
- 30 people
- Sponsor
- University of Coimbra
Central Post-Stroke Pain, Stroke
Accelerated Theta-Burst Stimulation for Refractory Central Post-Stroke Pain
This pilot study aims to evaluate the feasibility, safety, and preliminary efficacy of accelerated intermittent theta burst stimulation (aiTBS) as a noninvasive neuromodulation treatment for individuals with severe, refractory…
- Conditions
- Central Post-Stroke Pain, Stroke, Ischemic Stroke and Hemorrhagic Stroke
- Trial name
- NCT07909954
- Testing
- High-dose accelerated intermittent theta burst stimulation (aiTBS), Low-dose accelerated intermittent theta burst stimulation (aiTBS)
- Volunteers
- 30 people
- Sponsor
- Duke University
Central Post-Stroke Pain
Treatment of Post-Stroke Central Pain
To evaluate the short-term analgesic efficacy of stSCS combined with pharmacotherapy compared with pharmacotherapy alone in patients with CPSP, measured by Numerical Rating Scale (NRS) score immediately after treatment.
- Trial name
- NCT07593313
- Testing
- stSCS+Gabapentin or Pregabalin (with optional Duloxetine or Amitriptyline), Gabapentin or Pregabalin (with optional Duloxetine or Amitriptyline)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanchong Central Hospital
Stroke, Neuropathic Pain
Effect of Early Neuromodulation Coupled With Rehabilitation on the Prevention of Post-stroke Pain
This is a prospective clinical study to evaluate the efficacy of tDCS stimulation, coupled with conventional rehabilitation, on the development of post-stroke neuropathic pain.
- Conditions
- Stroke, Neuropathic Pain, Central Post Stroke Pain
- Trial name
- ENADA (NCT07202455)
- Testing
- Active tDCS
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Post-Stroke Hemiplegic Shoulder Pain
Ultrasound-Guided Pulsed Radiofrequency Versus Phenol Neurolysis for Post-Stroke Hemiplegic Shoulder Pain
Post-stroke hemiplegic shoulder pain is a common complication that negatively affects upper limb function and quality of life. This randomized controlled trial aims to compare the efficacy and safety of ultrasound-guided pulsed…
- Trial name
- NCT07753759
- Testing
- Pulsed radiofrequency neuromodulation, Ultrasound-guided phenol neurolysis
- Volunteers
- 70 people
- Sponsor
- Assiut University
Intracerebral Hemorrhage, Hemorrhagic Stroke
Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage
Spontaneous intracerebral haemorrhage (ICH) is a severe form of stroke with high mortality and frequent long-term disability. Current tools to predict how an individual patient will recover are limited.
- Trial name
- CR-4-Health (NCT07882784)
- Where
- 3 sites in Austria, Slovenia
- Volunteers
- 300 people
- Sponsor
- University Medical Centre Maribor
Post Stroke Pain
Scrambler Therapy for Post-Stroke Pain
The Investigators will enroll patients who have had a stroke and are experiencing post-stroke pain secondary to their infarct and disruption of the sensory system in a research study to compare the effectiveness of Scrambler…
- Trial name
- NCT05563038
- Testing
- Scrambler Therapy for Post Stroke Pain
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Post Stroke Shoulder Pain
To Evaluate the Therapeutic Effect of Laser Acupuncture in Patients With Acute or Subacute Post Stroke Shoulder Pain
Investigators propose a research design protocol to evaluate the efficacy of laser acupuncture in improving shoulder pain and improving shoulder function recovery after stroke.
- Trial name
- NCT05328401
- Testing
- Verum laser acupuncture
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- Chang Gung Memorial Hospital
Spinal Cord Injuries, Nerve Injury
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional…
- Conditions
- Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia
- Trial name
- NCT04144972
- Testing
- Medtronic Summit RC+S or Percept RC
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Stroke Sequelae, Neuropathic Pain
Prevalence of Central Neuropathic Pain After a Stroke in Patients Attending Post-stroke Consultations in the Île-de-France Region
Post-stroke pain is common, affecting 15-50% of patients and significantly impacting their quality of life, rehabilitation, and functional recovery.
- Trial name
- AVCD (NCT06813391)
- Testing
- Patient Reported Outcome (PRO)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Central Post Stroke Pain
Efficacy of Pain Intervention With Deep Brain Stimulation Neuromodulation
The goal of this clinical trial is to learn if deep brain stimulation (DBS) works to treat severe pain following a stroke in adults. It will also learn about the safety of deep brain stimulation.
- Trial name
- EPIONE (NCT06387914)
- Testing
- Stimulation ON, Stimulation Pseudo-ON
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
Stroke, Hemiplegic Shoulder Pain
Focal Vibration Therapy in Post-stroke Shoulder Pain
Hemiplegic Shoulder Pain (HSP) is a common and disabling complication after stroke, negatively affecting upper limb function, participation in rehabilitation, and quality of life.
- Conditions
- Stroke, Hemiplegic Shoulder Pain, Chronic Stroke Survivors
- Trial name
- VIBRA-HSP (NCT07513753)
- Testing
- Multimodal Focal Vibration Therapy (FVT), Standard Rehabilitation Program
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Foggia
Central Post-stroke Pain, Neuropathic Pain
Thalamic-Burst-DBS for Neuropathic Pain
Central post-stroke pain (CPSP) is a neuropathic pain syndrome and one of the major sequelae after ischemic or hemorrhagic cerebral stroke.
- Trial name
- NCT05204472
- Testing
- Burst DBS, Tonic DBS
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Post Stroke Pain
Post-stroke Pain tAN-fMRI
The purpose of this study is to explore whether 4 weeks of at-home transcutaneous auricular neurostimulation (tAN) can reduce chronic pain after a stroke.
- Trial name
- NCT07144436
- Testing
- Transcutaneous Auricular Neurostimulation
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Medical University of South Carolina