Clinical trials: Post Traumatic Stress Disorders
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Post-Traumatic Stress Disorders, Major Depressive Disorder
Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans
Co-occurring post-traumatic stress disorder (PTSD) and major depressive disorder (MDD) is the most common response to trauma; it is associated with poor clinical outcomes and substantial human disability.
- Trial name
- NCT04032301
- Testing
- Ketamine, Normal Saline
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
TBI (Traumatic Brain Injury)
Evaluation of Military Service and Family Members for Post Concussive and Posttraumatic Stress Symptoms
This protocol is designed to facilitate the recruitment, screening and registry of Military Service Members (SMs) and individuals eligible for care in the Department of Defense (DoD) healthcare system.
- Trial name
- MRP (NCT03191357)
- Testing
- n/a observational
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Post-traumatic Stress Disorder
Predictability of the Clinical Global Impression Scale (CGI) in Post Immediate in Psychotraumatic Impact
The objective of this study is to evaluate correlation between Clinical Global Impression Scale (CGI) score immediately in patients who have experienced psychotrauma and occurrence of posttraumatic stress disorder at distance…
- Trial name
- PRECLIP (NCT05358067)
- Where
- 4 sites in France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Arras
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Hypertension, Diabetes Mellitus
Hypertension and Diabetes Assessment in the Rohingya Refugee Population and in the Host Communities in Bangladesh
Due to a massive outbreak of violence against the Rohingya minority residing in the Rakhine State of Myanmar in late 2017, several hundred thousand Rohingya fled the country and sought a shelter in Bangladesh.
- Conditions
- Hypertension, Diabetes Mellitus, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT04307875
- Testing
- Blood pressure measurement (sphygmomanometer), Blood glucose measurement, psychometric tests
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Post-Traumatic Stress Disorder, Alcohol Drinking
Approach-Avoidance and Alcohol Challenge Study in PTSD
Individuals with posttraumatic stress disorder (PTSD) have greater prevalence of alcohol use disorders (AUDs), with this comorbidity associated with worse illness outcomes, yet there remains limited mechanistic understanding of…
- Trial name
- PACS (NCT06002633)
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Depression, Anxiety
Low Intensity Family Support for Refugees in an LMIC
The rapidly growing scale of humanitarian crises requires new response capabilities geared towards addressing populations with prolonged high vulnerability to mental health consequences and little to no access to mental health…
- Conditions
- Depression, Anxiety, PTSD, Family Dynamics
- Trial name
- NCT03978533
- Testing
- Family Support Group
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Ptsd, Depressive Symptoms
Transcendental Meditation and PTSD
This paper describes the rationale and design of a Phase 3 RCT comparing Transcendental Meditation to Present Centered Therapy for posttraumatic stress disorder (PTSD), suicidal ideation, alcohol use, and depressive symptoms in…
- Conditions
- Ptsd, Depressive Symptoms, Suicidal Ideation, Alcohol Use, Unspecified
- Trial name
- NCT04856033
- Testing
- TM, PCT
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- David Lynch Foundation
PTSD, Post-traumatic Stress Disorder
Network-based Neurofeedback in PTSD
This project will examine the use of real-time fMRI (rt-fMRI) neurofeedback in the regulation of neural networks underlying symptoms experienced by individuals with posttraumatic stress disorder (PTSD).
- Trial name
- NCT04875221
- Testing
- Connectivity-based neurofeedback
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Posttraumatic Stress Disorder, Stress Disorders, Post-Traumatic
Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder
The primary goal of this pilot project is to demonstrate the safety and feasibility of using Cannabidiol (CBD) in combination with standard of care prolonged exposure (PE) psychotherapy to reduce PTSD symptoms.
- Trial name
- NCT05132699
- Testing
- Cannabidiol (CBD) oral solution, Massed Prolonged Exposure (mPE)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Posttraumatic Stress Disorder, Somatization
Intervention Through EMDR and CBT With Women Victim of Childhood Sexual Abuse. A Randomized Controlled Trial.
This study evaluates the effectiveness of two types of therapy for the treatment of sexual abuse psychological impact on a sample of Spanish women.
- Conditions
- Posttraumatic Stress Disorder, Somatization, Obsessive-Compulsive Disorder, Depression
- Trial name
- NCT04813224
- Testing
- TRAUMA CENTERED EMDR-BASED TREATMENT and TRAUMA-FOCUSED CBT-BASED TREATMENT
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Post-Traumatic Stress Disorders, Healthy
Effects of Hydrocortisone in Patients With Post-Traumatic Stress Disorder
The purpose of this study is to determine whether people who develop Post-Traumatic Stress Disorder (PTSD) after a trauma have increased sensitivity to the effects of a stress hormone.
- Trial name
- NCT00039715
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Post-traumatic Stress Disorder (PTSD), Anxiety Symptoms
The Impact of Playing Tetris on Migrants' Mental Health
This study examines if playing Tetris prevents the development of Post-traumatic stress disorder or related anxiety and depressive symptoms. The investigators recruit 300 participants in total in Greece and in the Netherlands.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Anxiety Symptoms, Depression Symptoms
- Trial name
- NCT06773338
- Testing
- Tetris, No intervention
- Where
- 2 sites in Greece, Netherlands
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tilburg University
Post-Traumatic Stress Disorders
Mental Health in Veterans and Families After Group Therapies
PTSD (posttraumatic stress disorder) and associated mental health conditions affect both veterans and their family members. This study investigates whether group therapy using EFT (Emotional Freedom Techniques) and CBT (Cognitive…
- Trial name
- NCT01327690
- Testing
- CBT (Cognitive Behavior Therapy), EFT (Emotional Freedom Techniques)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soul Medicine Institute
Hyperthermia
Semiconductor Heat Extraction Cooling
Heat-related injuries and other physiological stresses continue to be a significant threat to the health and operational effectiveness of the US Armed Forces (Armed Forces Health Surveillance 2011).
- Trial name
- SHE-Cool (NCT04915859)
- Testing
- Hand Cooling at 12-15 degrees celsius, Hand Cooling at 16-20 degrees celsius, hand and back cooling at 12-15 or 16-20 degrees celsius
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Intensive Care, Child
The Visiting Child and His Family in ICU
According to literature, it's difficult to evaluate the impact of the visit of the child in ICU. Currently, no recommendations are available regarding welcome and accompany children who visit their relative hospitalized in ICU.
- Conditions
- Intensive Care, Child, Acute Stress Disorder, Post Traumatic Stress Disorder
- Trial name
- ENVIFAR (NCT03954522)
- Testing
- interview
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD)
Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders
The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders.
- Conditions
- Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT07604753
- Testing
- CIDI-5
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Post-Traumatic Stress Disorder Complex, Emotional Dysregulation
Child-Parent Psychotherapy After the 2023 Kahramanmaraş Earthquake
This study aims to evaluate the effectiveness of Child-Parent Psychotherapy (CPP) in reducing trauma-related symptoms and improving attachment quality among preschool-aged children who experienced the 2023 Kahramanmaraş…
- Trial name
- NCT07040462
- Testing
- Child-Parent Psychotherapy (CPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beykoz University
Depression, Anxiety
Cognitive Processing Therapy in Syrian Women Exposed to IPV
This study aims to explore the efficacy of cognitive processing therapy (CPT) in treating depression, anxiety, PTSD, and difficulties with emotion regulation in Syrian females who have suffered intimate partner violence (IPV).
- Conditions
- Depression, Anxiety, PTSD
- Trial name
- NCT05674591
- Testing
- Cognitive Processing Therapy (CPT)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- British University In Egypt