Clinical trials: Post Viral Fatigue
Long COVID, Post COVID-19 Condition
Investigating the Effectiveness of Vimida
This randomized controlled trial (RCT) with 160 patients suffering from fatigue after COVID-19 infection aims to investigate the effectiveness of the unguided digital therapeutic vimida for reducing post-COVID-19 fatigue.
- Trial name
- InvidiCO (NCT06251518)
- Testing
- vimida
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Gaia AG
Multicausal Fatigue, Fatigue
Micro-choice-based Intervention for Multicausal Fatigue
This proof-of-concept study aims to evaluate the feasibility, acceptability, and potential benefits of a novel multimodal approach: the micro-choice-based intervention.
- Conditions
- Multicausal Fatigue, Fatigue, Post COVID Condition, Long COVID Syndrome
- Trial name
- CHOOSE-POC (NCT07726082)
- Testing
- Micro-choice-based intervention
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University Hospital, Basel, Switzerland
Post-Acute COVID-19 Syndrome, Fatigue
Dietary Intervention to Mitigate Post-Acute COVID-19 Syndrome
The primary objective of this study is to conduct a 16-week randomized controlled trial aimed at investigating the effectiveness of the Whole-Diet Approach when following a healthy US-style diet rich in anti-inflammatory…
- Trial name
- Long-COVIDiet (NCT05977179)
- Testing
- Dietary intervention to mitigate Post-Acute COVID-19 Syndrome, Attention Control
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Maryland, Baltimore
Fatigue, Cognitive Deficit
Effects of PEA-LUT on Frontal Lobe Functions and GABAergic Transmission in Long-Covid Patients
The study explore the efficacy of PEA-LUT in patients suffering from neurological symptoms of Long-Covid
- Conditions
- Fatigue, Cognitive Deficit, COVID-19, Neurophysiologic Abnormality
- Trial name
- PL-PC19 (NCT05311852)
- Testing
- palmitoylethanolamide co-ultramicronized with antioxidant flavonoid luteolin (PEA-LUT)
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Department of Neurorehabilitation, Hospital of Vipiteno-Sterzing (BZ) Italy
Post-COVID-19 Syndrome
The Effect of Amantadine on Post-COVD-19 Fatigue
This study aimed to investigate amantadine's safety and its effect on reducing post-COVID-19 fatigue.
- Trial name
- NCT05667077
- Testing
- Amantadine
- Where
- Iran
- Volunteers
- 83 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
COVID-19, Brain Fog
Transcranial Ultrasound Stimulation for Cognitive Function Modulation in Patients With Post COVID-19 Brain Fog
This study aims to investigate whether a specific brain region mediates the cognitive deficit in long COVID brain fog, and whether targeted modulation of this region can improve cognition.
- Conditions
- COVID-19, Brain Fog, Long COVID, Transcranial Ultrasound Stimulation
- Trial name
- NCT07154199
- Testing
- real transcranial ultrasound stimulation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Post-Acute COVID-19, Long COVID
Personalized Computerized Training Program for Cognitive Dysfunction After COVID-19
This before-and-after study aims to evaluate the usefulness and efficacy of a personalized computerized cognitive training (CCT) to improve cognitive function among people with post-acute sequelae of COVID-19 (PASC).
- Trial name
- NCT05571852
- Testing
- CogniFit's CCT Post COVID-19
- Where
- Spain
- Volunteers
- 73 people
- Sponsor
- Universidad Antonio de Nebrija
Long COVID
The Efficacy and Safety of a Chinese Herbal Medicine for Long COVID Associated Fatigue
This is a randomized, double-blinded, placebo-controlled clinical trial to determine the efficacy and safety of a Chinese herbal medicine (Shenlingcao oral liquid) for treating long COVID associated fatigue.
- Trial name
- NCT05684952
- Testing
- Shenlingcao Oral Liquid
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Hong Kong Baptist University
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis
Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
The primary objective of the present research is to determine the effectiveness of Family Health Center of San Diego's Long COVID and Fatiguing Illness Recovery Program (LC\&FIRP) on clinician- and patient-level outcomes.
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection
- Trial name
- LC&FIRP (NCT05167227)
- Testing
- Extension for Community Healthcare Outcomes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Family Health Centers of San Diego
PASC Post Acute Sequelae of COVID 19, Fatigue
Neural Mechanisms of Fatigue in Post-Acute Sequela of SARS-CoV-2
This proposal aims to understand the neurobiological mechanisms of fatigue in individuals with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC).
- Trial name
- NCT07278388
- Testing
- Physical Fatigue
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Post-acute Infectious Syndrome (PAIS), Post-COVID 19 Condition (PCC or Long COVID)
CD19-B Cell Depletion in PAIS-ME/CFS Patients
Post-acute infection syndromes (PAIS) are long-lasting health problems that can develop after an infection. They include post-COVID-19 syndrome and similar illnesses following other infections.
- Conditions
- Post-acute Infectious Syndrome (PAIS), Post-COVID 19 Condition (PCC or Long COVID), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
- Trial name
- PIONEER_PAIS (NCT07724834)
- Testing
- Inebilizumab
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Charite University, Berlin, Germany
Covid19, Burnout, Professional
Mental Health of Professionals Working in Pediatric Intensive Care Units During the COVID-19 Pandemic
Health professionals are extremely exposed to psychosocial risks, as they experience, in general, high levels of stress, anxiety, fatigue and suffering, due to the nature and location of their work.
- Conditions
- Covid19, Burnout, Professional, Stress Disorders, Post-Traumatic, Anxiety
- Trial name
- NCT04846907
- Testing
- Web-based survey
- Where
- Brazil
- Volunteers
- 1,148 people, healthy volunteers welcome
- Sponsor
- D'Or Institute for Research and Education
COVID-19 Pneumonia
Neuromuscular Electrical Stimulation in Patients With COVID19 Associated Pneumonia
Neuromuscular electrical stimulation (NMES) has been considered as a promising approach for the early rehabilitation of patients in and/or after the intensive care unit (ICU).
- Trial name
- NCT04382729
- Testing
- Neuromuscular Electrical Stimulation, Physical Therapy Exercise
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Turin, Italy
COVID-19
The Effects of a Multi-factorial Rehabilitation Program for Healthcare Workers Suffering From Post-COVID-19 Fatigue Syndrome
The SARS-CoV2 pandemic has kept the world in suspense for over a year now. Almost 100 million people around the world have contracted COVID-19 to date and over 2 million people have died of COVID-19 by the end of January 2021.
- Trial name
- NCT04841759
- Testing
- Exercise
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Post-Acute Sequelae of SARS-CoV-2 (PASC) Infection
Efficacy, Safety, Tolerability of AXA1125 in Fatigue After COVID-19 Infection
This study will compare the effects of AXA1125, an orally active mixture of amino acids, compared to placebo, on improving muscle function (metabolism) following moderate exercise in subjects with fatigue-Predominant Post-Acute…
- Trial name
- NCT05152849
- Testing
- AXA1125
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Axcella Health, Inc
Chronic Fatigue Syndrome
Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder
The pathogenesis of chronic fatigue syndrome (CFS) is poorly understood and no effective therapy has been developed. Recent studies suggest that a preceding viral infection causes mitochondrial dysfunction of the brain and…
- Trial name
- CFS:M (NCT01471652)
- Testing
- Nutraceutical supplements
- Where
- United States
- Sponsor
- Columbia University
Long-COVID, Long COVID-19
Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial
Long COVID is a complex condition that affects approximately 1.4 million Canadians following SARS-CoV-2 infection. Fatigue is the most common symptom of Long COVID.
- Conditions
- Long-COVID, Long COVID-19, Post-COVID-19 Syndrome, Post-COVID Syndrome
- Trial name
- PREFACER (NCT06156176)
- Testing
- COVIDEx
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Lawson Research Institute of St. Joseph's
Post-COVID-19
Sleep Characteristics in Post-COVID-19 Patients
After acute infection, patients with coronavirus disease 2019 (COVID-19) often suffer from persisting symptoms for more than 3 months (post COVID-19).
- Trial name
- NCT05124548
- Testing
- Sleep diagnostics
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Schön Klinik Berchtesgadener Land
COVID Long-Haul, COVID-19
Neural and Cognitive Consequences of COVID-19 Survival
The novel coronavirus SARS-CoV-2 infection, COVID, continues to rage throughout the world with 115,000,000 confirmed cases and over 2,500,000 deaths (as of Mar 3, 2021).
- Conditions
- COVID Long-Haul, COVID-19, COVID-19 Pandemic, Brain Fog
- Trial name
- NCT06208943
- Testing
- cross-sectional MRI and EEG assessments (NO INTERVENTION)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Cardiorespiratory Fitness, Exercise
Tele-Rehabilitative Exercise Training Program in Nurses With Long COVID
Long COVID can cause a decline in cardiorespiratory fitness, resulting in fatigue and negative impacts on individuals' quality of life (QoL), particularly in nurses who play a crucial role in public health.
- Conditions
- Cardiorespiratory Fitness, Exercise, Long COVID, Nurses
- Trial name
- NCT06840873
- Testing
- wearable device, Healthy consulation
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Shang-Lin Chiang