Clinical trials: Post-COVID Condition
Fatigue Syndrome, Chronic, Inflammation
Evaluation of the Effects of Treatment With Bioarginin C in Adult Subjects Belonging to the Post-Covid Day Hospital
Long Covid could be much more frequent than it is thought to be. Few dwell on the great problem represented by the post covid syndrome.
- Trial name
- BC (NCT04947488)
- Testing
- Bioarginina C
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Milan
Coronavirus Disease 2019, Coronavirus Disease 2019 (COVID-19)
A Study of How Ibuzatrelvir is Taken up Into the Blood of Healthy Adults After Taking Different Tablets of Ibuzatrelvir
Healthy adults will be enrolled into this open-label, Phase 1 research study. Participants will spend about 9 nights and 10 days in the clinical research unit (CRU) and the total time in the study will be about 11 weeks.
- Conditions
- Coronavirus Disease 2019, Coronavirus Disease 2019 (COVID-19), COVID-19 (Coronavirus Disease 2019), Upper Respiratory Tract Infections
- Trial name
- NCT07552779
- Testing
- Ibuzatrelvir co-process API film coated tablet, Ibuzatrelvir filmcoated tablet
- Where
- Belgium
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Pfizer
Long COVID, COVID-19 Pandemic
Long COVID and Its Associations With Health Outcomes in Older Adults
The Peking University Health Cohort in Anning, Yunnan (PKUHC-AN) is a prospective cohort study carried out in Anning, Yunnan. The primary aim of this study is to investigate the impact of COVID-19 on older adults' health, and to…
- Conditions
- Long COVID, COVID-19 Pandemic, Elderly Infection, Vaccine Reaction
- Trial name
- NCT05825651
- Testing
- no interventions
- Where
- China
- Volunteers
- 11,527 people, healthy volunteers welcome
- Sponsor
- Peking University
Mitochondrial Dysfunction, COVID-19
In Vivo Investigation on Mitochondrial Dysfunction in Post-COVID Fatigue and Cancer Fatigue.
To date, little is understood regarding post-COVID fatigue or cancer fatigue though it is known to affect a large proportion of patients (10-70% depending on the population).
- Conditions
- Mitochondrial Dysfunction, COVID-19, Fatigue
- Trial name
- NCT05753228
- Testing
- MRI/ 3D Arterial Spin Labelling (ASL) and 1H magnetic resonance spectroscopy (MRS), Chalder Fatigue Scale, Health Questionnaire (EQ-5D-5L)
- Where
- Singapore
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Long COVID, Post-COVID-19 Condition
Mitochondrial Function in Peripheral Blood Mononuclear Cells, Muscle, and Skin of Long COVID Patients
Mitochondria are structures inside cells that are responsible for producing energy from nutrients through a series of steps, using oxygen.
- Trial name
- MitoLoCo (NCT07134673)
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Stress Disorders, Post-Traumatic
Alterations of Gut Microbiome in the Frontline Medical Staff Under the Stress
With the outbreak of 2019 novel coronavirus (2019-nCoV), the frontline medical workers faced enormous stress, including a high risk of infection and inadequate protection from contamination, isolation, patients with negative…
- Trial name
- AGMFMSS (NCT04443075)
- Testing
- faecal sample collector
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Covid19
The Effect of Probiotic Supplementation on SARS-CoV-2 Antibody Response After COVID-19
This study will explore how a well-known probiotic strain L. reuteri DSM 17938 impacts SARS-CoV-2 specific antibody response upon and after infection in healthy adults.
- Trial name
- NCT04734886
- Testing
- L. reuteri DSM 17938 + vitamin D
- Where
- Sweden
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
COVID-19, Long COVID
Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI)
We are conducting a research study at the VA hospital in Bedford, MA to learn more about how a multisensor rapid health assessment device, MouthLab, can help predict or anticipate future health complications in patients with…
- Trial name
- AIDI (NCT05713266)
- Testing
- MouthLabTM
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Edith Nourse Rogers Memorial Veterans Hospital
Long Covid
The Effect of Acupuncture Treatment on Cognitive Functions and Brain Networks for Long COVID
Background of study: Long COVID(LC) is a prevalent sequalae of SARS-CoV-2 infection and can affect multiple organ systems. Cognitive dysfunction is one of the most common symptoms in LC with 22% prevalence.
- Trial name
- NCT07355751
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Tingting Luo
COVID-19, Dyspnea
Short Term Results of Tele-Rehabilitation
Most people who have coronavirus disease (COVID-19) recover completely without any sequelae. However, some patients continue to experience symptoms of COVID-19 even though their tests turn negative.
- Trial name
- NCT05381675
- Testing
- Tele-rehabillitation, Prescribed Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Harran University
Long COVID, Brain Fog
Effect of Probiotic Strain Lactobacillus Paracasei PS23 on Brain Fog in People With Long COVID
The goal of this clinical trial is to test whether the intervention of probiotics supplement can improve symptoms of long covid syndrome. Participants will be given probiotics or placebo capsules for two month.
- Conditions
- Long COVID, Brain Fog, Cognitive Change
- Trial name
- COVID-19 (NCT06348212)
- Testing
- Lactobacillus paracasei PS23, microcrystalline cellulose
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
COVID-19
Heterologous Boost Immunization with Ad5-nCoV After Three-dose Priming with an Inactivated SARS-CoV-2 Vaccine
This is an open-label, randomized, parallel-controlled clinical trial to evaluate the safety and immunogenicity of heterologous prime-boost immunization with an aerosolized (Ad5-nCoV-IH) or intramuscular (Ad5-nCoV-IM) Ad5-nCoV…
- Trial name
- NCT05303584
- Testing
- Ad5-nCoV-IH, Ad5-nCoV-IM, CoronaVac
- Where
- China
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
COVID-19, Cancer
SARS-CoV-2 Specific Immune Response After COVID-19 Vaccination in Cancer Patients
Our study highlights a low degree of neutralization-afforded protection mounted by CoronaVac in cancer patients when compared with healthy volunteers, especially patients who received chemotherapy.
- Trial name
- NCT05313074
- Testing
- CoronaVac vaccine
- Where
- Thailand
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Thailand
Covid19
Safety and Immunogenicity Trial of an Oral SARS-CoV-2 Vaccine (VXA-CoV2-1) for Prevention of COVID-19 in Healthy Adults and Boost (VXA-CoV2-1.1-S) at 1 Year Post Initial Vaccination in Subset of Subjects
VXA-CoV2-1 is a non-replicating Ad5 vector adjuvanted oral tableted vaccine being developed to prevent COVID-19, the disease resulting from Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) infection.
- Trial name
- NCT04563702
- Testing
- VXA-CoV2-1
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Vaxart
COVID19- Infection with SARS-CoV-2 Virus, SARS-CoV-2 Positive Patients
Impact of the Elevation Training Mask in CrossFit® Post-SARS-CoV-2 Infection.
Introduction: The Elevation Training Mask (ETM) could restore respiratory or hematological organic damages from the acute or post-infection phase of severe acute respiratory syndrome coronavirus 2 (SARSCoV2) because it would…
- Conditions
- COVID19- Infection with SARS-CoV-2 Virus, SARS-CoV-2 Positive Patients, COVID-19 Pulmonary Complications, SARS-CoV-2 Infection (Symptomatic)
- Trial name
- ETMEXCOVID (NCT06806124)
- Testing
- Elevation Training Mask
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
COVID-19
Follow-up of Patients With Previous SARS-CoV-2 Infection: Long-term Damage Assessment
People affected by SARS-CoV-2 infection, whether patients have developed mild forms or a severe form of the disease, complain of nonspecific and entirely new symptoms or complain about the persistence pf them.Investigators intend…
- Trial name
- NCT05359159
- Testing
- Data collection
- Where
- 2 sites in Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Covid19, Post-COVID / Long-COVID
Post-coronavirus Disease-2019 Fatigue
Background: COVID-19 is consistently spreading throughout the world, and the number of recovered patients is steadily increasing.
- Trial name
- NCT04851561
- Testing
- Cardiopulmonary stress test (CPET)
- Where
- Israel
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Covid19_rehabilitation
Recovery Profiles in Patients With SARS-CoV-2 Outcomes Undergoing Rehabilitation
COVID19 patients survivors, after discharge from hospital show reduced lung function and reduced ability to exercise. Furthermore, mental health problems including stress, anxiety and depression and a low quality of life were…
- Trial name
- NCT04615390
- Testing
- Early rehabilitation, Subacute rehabilitation, Mindfulness training
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
LONG-COVID, Post-acute Sequelae of COVID-19
Skeletal Muscle in PASC and ME/CFS Patients
Rationale: A common feature in patients with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) and Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are skeletal muscle-related symptoms, such as muscle pain, weakness…
- Conditions
- LONG-COVID, Post-acute Sequelae of COVID-19, ME/CFS
- Trial name
- NCT05225688
- Testing
- Bike exertion test
- Where
- Netherlands
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Multisystem Inflammatory Syndrome in Children (MIS-C), SARS-CoV-2 Infection
Cardiovascular Assessment 5 Years After MIS-C
Multisystem inflammatory syndrome in children (MIS-C) is a severe complication associated with SARS-CoV-2 infection that frequently affects the cardiovascular system.
- Trial name
- NCT07659847
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw