Clinical trials: Post-Extraction Sockets
Orthodontic Extraction
Comparison of Rate and Amount of Orthodontic Space Closure
The goal of this clinical trial is to compare rate and amount of space closure among fresh vs healed extraction sites during fixed orthodontic treatment in patients with all first premolar's extraction Primary outcome measure is…
- Trial name
- Premolar (NCT07445321)
- Testing
- Space Closure
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Extracting Own Teeth
Evaluation of Bone Behavior in Maxillary Post-extractive Sites Treated With Guided Bone Regeneration (G.B.R.) Techniques in Alveolar Socket Preservation (A.S.P.) Procedures With Different Autologous and Heterologous Biomaterials.
The maxillary bone atrophies from traumatic, pathological events or related to physiological bone loss after tooth extraction, promoting a decrease in bone volume (vertical-horizontal) which has always been a crucial challenge…
- Trial name
- NCT07269990
- Testing
- compare different types of biomaterials 4 months after application through the use of ASP compare different types of biomaterials 4 months after application through the use of ASP Group 2, Comparison of different types of biomaterials 4 months after application through the use of ASP, Comparison different types of biomaterials 4 months after application through the use of ASP
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Socket Preservation
Evaluation of Dentin Graft and I-PRF With and Without Vitamin C for Post-extraction Socket Preservation
The aim of the study is to evaluate radiographic ridge width change following autogenous demineralized dentin graft (ADDG) and i-PRF addition with and without vitamin C (AA) for post extraction socket preservation.
- Trial name
- NCT06569264
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin graft and i-PRF, Alveolar ridge preservation using vitamin C with dentin graft and i-PRF
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Socket Preservation
Evaluation of Bone Changes After Immediate Implant Placement or Socket Preservation With or Without Surgical Flap in The Aesthetic Zone
The amount of hard tissue resorption following tooth extraction involves prosthetically driven implant placement; therefore, the development of ridge preservation techniques that result in less alveolar bone loss is of great…
- Trial name
- NCT03690973
- Testing
- Alveolar socket preservation with graft and flap surgery, Immediate implant placement with bone using flapless surgery, Immediate implant placement with bone using flap surgery
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Extracted Socket
Effect of Black Tea Extract Impregnated Gauze on Extracted Socket
Black tea is made from the leaves of a bush called Camellia sinensis. The main difference between green tea and black tea is that green tea is not completely oxidized while black tea is fully oxidized.
- Trial name
- BTEIG (NCT06687824)
- Testing
- Black Tea Extract, 0.5% Povidone Iodine Impregnated Sterile Gauze
- Where
- Malaysia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Manipal University College Malaysia
Impacted Third Molar Tooth
Gum Health Gel in Post Extraction Sockets
This research studies the effectiveness of the Gum Health gel in minimizing post operative sequelae associated with the surgical removal of impacted mandibular third molars
- Trial name
- Gum Health gel (NCT06251141)
- Testing
- Gum Health gel, Gel foam
- Where
- Iraq
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain, Dry Socket
Ozone Oil-based Gel and CHX Gel After Lower Third Molar Removal
Overall, 100 patients of both genders were included in the study, with indication of surgical extraction of lower third molar, positioned similarly after being clinically and radiographically checked by X-ray and…
- Trial name
- NCT07549672
- Testing
- Ozone Oil-based Gel
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, Dental Caries
Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing
The aim of this study is to determine the beneficial effect of mouth rinses, both topical analgesic and saline regimens as an adjuvant therapy in the presence of standard prescription of post-operative pain killers on the…
- Conditions
- Periodontitis, Dental Caries, Hypertension
- Trial name
- NCT02921165
- Testing
- analgesic mouth rinses (dissolved Aspirin), Normal saline rinses.
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Alveolar Ridge Augmentation
PeptiCol EZgraft in the Extraction Socket Preservation Process After Tooth Extraction
This clinical trial aims to compare the efficacy and safety of applying "PeptiCol EZgraft" in extraction socket preservation procedures against "Regenomer," in terms of reducing the amount of alveolar bone change during the…
- Trial name
- NCT06783660
- Testing
- Peptide-loaded collagen sponge and collagen gel complex, Collagen sponge
- Where
- South Korea
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- NIBEC Co., Ltd.
Alveolar Osteitis
The Effect of Post-extraction Collagen Sponge Application on Alveolar Osteitis
The goal of this randomized controlled trial is to compare pain, mouth opening, and alveolar osteitis following surgical extraction of bilateral symmetrical impacted lower third molars using two types of wound closures.
- Trial name
- NCT05850650
- Testing
- Application of a collagen sponge after surgical extraction of impacted 3rd molar, No collagen sponge application after surgical extraction of impacted 3rd molar
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Impacted Mandibular Third Molar, Alveolar Bone Loss
Healing of Mandibular Third Molar Extraction Sockets Using Platelet Concentrates and Photobiomodulation
Surgical removal of impacted mandibular third molars is a common procedure that may be associated with postoperative pain, swelling, limited mouth opening, and delayed bone healing.
- Conditions
- Impacted Mandibular Third Molar, Alveolar Bone Loss, Impacted Mandibular Third Molar Extraction
- Trial name
- NCT07324213
- Testing
- Mandibular Third Molar Extraction With Primary Wound Closure, Autologous Platelet Concentrates, Photobiomodulation
- Where
- Poland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Socket Preservation
Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus L- PRF Block
The aim is to evaluate post extraction hard tissue changes following ridge preservation using partially demineralized dentin block versus L-PRF block in intact socket in the esthetic zone.
- Trial name
- NCT06275490
- Testing
- Partially Demineralized Dentin Block, L-PRF block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dimensional Changes After Tooth Extraction, Tooth Extraaction
Alveolar Ridge Preservation Using Autogenous Whole Tooth Graft With 1 %Metformin :A Randomized Controlled Clinical Trial
This study describes a technique used to preserve the bone dimensions after the tooth extraction inorder to facilitate later on the dental implant placement
- Conditions
- Dimensional Changes After Tooth Extraction, Tooth Extraaction, Socket Preservation
- Trial name
- NCT07086859
- Testing
- TEST 1, Control
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Extraction
A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction
This study will be a randomized clinical trial involving a total of 24 subjects. The investigators propose to recruit subjects into 2 groups: 1) Extraction treated with xenograft bone substitute (BioOss Collagen®) + collagen…
- Trial name
- NCT02844569
- Testing
- Xenograft bone substitute, Collagen dressing, 3D-collagen matrix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Alveolar Bone Loss, Tooth Extraction
Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing
This study evaluates two different treatments used to help the jawbone heal after a tooth is removed. When a tooth is extracted, the surrounding bone often shrinks, which can make it difficult to place dental implants later.
- Conditions
- Alveolar Bone Loss, Tooth Extraction, Bone Regeneration
- Trial name
- MSC-EXO vs PRF (NCT07508033)
- Testing
- MSC-Derived Exosomes, Platelet-rich fibrin (PRF)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al Salam University
Alveolar Socket Preservation
Clinical, Histological and Micro-computed Tomographic Evaluation of Neoformed Tissue in Post-extraction Sockets Covered With Platelet-rich Fibrin (PRF) Membrane: a Randomized Controlled Trial
The platelet-rich fibrin (PRF), belongs to a new generation of plasma concentrate with biomechanical processing simplified and without the need for handling blood biochemistry.
- Trial name
- NCT02300246
- Testing
- Platelet-Rich Fibrin
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Marcos de Oliveira Barceleiro
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Relate Tooth Alveolar Extraction Socket Anatomy to Alveolar Remodeling Rate
In patients that are going to be subjected to a tooth extraction in the anterior maxillary (from canine to canine) does the position of the intact alveolar socket related to maxillary basal bone interferes with the rate of…
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Bone Resorption
- Trial name
- NCT01963884
- Testing
- Tooth Extraction, Cone-Beam technology evaluation, Measure Alveolar Socket Remodeling
- Where
- Portugal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Pain, Postoperative, Post Operative Swelling
Effect Of Autologous Platelet Rich Fibrin On Post-Operative Complications And Healing Following The Extraction
As post-operative pain, infection inflammation and infections are the main complications after the surgical extraction of the lower third molar the aim of this study is to compare the healing effects of PRF administered…
- Conditions
- Pain, Postoperative, Post Operative Swelling, Trismus, Soft Tissue Healing
- Trial name
- PRF (NCT06609967)
- Testing
- application of PRF, application of conventional surgicel
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Tooth Extraction, Atrophy of Edentulous Alveolar Ridge
Ridge Preservation With New Class of Osteoplastic Materials
Return to normal life and shortening rehabilitation period of patients after surgical removal of teeth is important and urgent social problem.
- Trial name
- RP (NCT02155764)
- Testing
- Octacalcium phosphate, Bio-Oss, Tricalcium phosphate
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Osteogenesis Imperfecta, Total Absence of Permanent Teeth
Site Preservation After Tooth Extraction
This study is mainly targeted affected teeth which could not be retained, and patients are willing to undergo implant repair at the later stage.
- Conditions
- Osteogenesis Imperfecta, Total Absence of Permanent Teeth, Tooth Socket
- Trial name
- NCT05258019
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University