Clinical trials: Post-Mastectomy
Mastectomy, Modified Radical
Intraoperative Pectoral Block vs IV Analgesia for Pain After Modified Radical Mastectomy
There is difference in post operative pain between patients receiving inter- pectoral block and those receiving standard Intravenous analgesia(INJ TORADOL) in patients undergoing Modified Radical Mastectomy.
- Trial name
- NCT07257874
- Testing
- bupivacaine 0.5% injection, Ketorolac 30 mg IV
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Islamabad Medical and Dental College
Breast Cancer, Postoperative Pain
Comparison of Combined (Superficial and Deep) and Isolated Deep Serratus Anterior Plane Blocks After Breast Surgery
The main purpose of this study is to compare the effectiveness of two different regional anesthesia techniques for pain management after oncological breast surgeries.
- Conditions
- Breast Cancer, Postoperative Pain, Pain Management After Surgery
- Trial name
- NCT07724678
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- SBU Ankara Egitim ve Arastirma Hastanesi
More Effective Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination, More Prolonged Duration of Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination
Comparing Effect of Adding Ketamine Versus Dexmedetomidine to Bupivacaine in Pec 11 Modified Block on Postoperative Pain Control in Patients Undergoing Breast Surgery
in our study we are trying to reach to the preferred adjuvant from either ketamine or dexmedetomidine to be added to bupivacaine local anesthetic during pec 11 modified block as regard its efficacy and duration of postoperative…
- Trial name
- NCT04380168
- Testing
- Modified pec11 trunk block
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Ain Shams University
Breast Cancer, Mastectomy
Post-Operative Outcomes of Low Thermal Dissection vs. Traditional Electrosurgery
Low thermal dissection devices have been introduced as a tool to improve surgical outcomes. PlasmaBlade, a low thermal dissection device, has shown to be associated with effective cutting, and significantly lower temperature than…
- Conditions
- Breast Cancer, Mastectomy, Perfusion; Complications, Hemostasis
- Trial name
- NCT03711916
- Testing
- PlasmaBlade 3.0S
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Breast Cancer Female, Breast Cancer Prevent
First-in-human, Study of MATTISSE® Tissue Engineering Chamber in Adult Female Patients Undergoing Breast Reconstruction After Mastectomy for Cancer
This study is a first in human, two-stage single arm non-comparative study of safety and performance. The aim of the study is to asses the safety and the clinical performance of a new device : the MATTISSE tissu engineering…
- Conditions
- Breast Cancer Female, Breast Cancer Prevent, Breast Reconstruction
- Trial name
- TIDE (NCT05460780)
- Testing
- MATTISSE TEC
- Where
- 3 sites in France, Georgia
- Volunteers
- 50 people
- Sponsor
- Quanta Medical
Breast Reconstruction After Mastectomy
A Comparative Study of Delayed Endoscopic DTI and Autologous Flap Reconstruction Post-Mastectomy
In China, low breast-conserving surgery rates and historically minimal immediate reconstruction following mastectomy have resulted in a significant population of women living without a breast, often leading to long-term…
- Trial name
- DEDIA (NCT07602868)
- Volunteers
- 263 people
- Sponsor
- West China Hospital
Breast Neoplasms, Radiotherapy Side Effect
3D Printed Bolus in Post-mastectomy Radiotherapy
Recently, there is growing interest in the application of three-dimensional (3D) printed bolus to radiotherapy.At present, the researches on the application of 3D-printed bolus in breast cancer are mainly focused on air gap…
- Trial name
- NCT04685460
- Testing
- customized 3D-printed bolus fabricated based on reconstruction of computed tomography (CT) images
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Breast Cancer
Safety Study of the Hypo-fractionated (Large Doses) Radiation Therapy in Post-menopausal Women With Breast Cancers
The purpose of this study is to determine whether high dose of radiation therapy (RT) are effective over standard 6-week radiation treatment in patients with breast cancer
- Trial name
- NCT02883985
- Testing
- 6 Gy/ fraction
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Breast Cancer, Mastectomy
Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy
The purpose of this study is to see if pre-operative regional nerve blocks compared to a placebo nerve block can decrease chronic post mastectomy pain, immediate postoperative pain and postoperative narcotic consumption.
- Conditions
- Breast Cancer, Mastectomy, Anesthesia, Local, Narcotic Use
- Trial name
- RELIEF (NCT04019834)
- Testing
- regional nerve block with local anesthesia of bupivacaine with steroid
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Reconstruction, Breast Reconstruction Following Mastectomy
Post-market Prospective Clinical Study of Nagor Perle Mammary Implants
Patients can undergo breast implant surgery for multiple reasons; cosmetic and reconstructive being the primary indications. In order to confidently state safety and due to strict regulation on medical devices it is important to…
- Conditions
- Breast Reconstruction, Breast Reconstruction Following Mastectomy, Breast Revision, Breast Augmentation
- Trial name
- PERLE10PMCF (NCT06013514)
- Testing
- PERLE Sterile Smooth Opaque gel filled mammary implants
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- GCA (Eurosilicone)
Postoperative Pain, Postoperative Nausea and Vomiting
Pre-pectoral AlloDerm® to Reinforce Tissues in Tissue Expander Breast Reconstruction
Primary Objective: To describe postoperative static pain scores on the Pain Visual Analog Scale at Day 1 in a population of women undergoing bilateral mastectomy followed by immediate, bilateral pre-pectoral tissue expander…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Quality of Life, Breast Cancer
- Trial name
- NCT03195322
- Testing
- Pre-pectoral Tissue Expander
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Skin Necrosis, Complication
Efficacy of Angiography With Indocyanine Green in the Identification of Complications After Breast Surgery
During the performance of oncoplastic surgery and skin-sparing or skin-nipple mastectomy there is a significant loss in the perfusion of the cutaneous envelope of the breast, which can produce areas of vascular suffering of the…
- Trial name
- NCT05910931
- Testing
- ICG angiography
- Where
- Spain
- Volunteers
- 221 people
- Sponsor
- University Hospital A Coruña
Breast Cancer, Radiodermatitis
Clinical Trial of The Use of Bolus in Post Mastectomy Irradiation in Breast Cancer
The aim of this study is to evaluate the impact of adding bolus in adjuvant radiotherapy after mastectomy, in relation to the time of treatment interruption and acute effects.
- Trial name
- NCT01925651
- Testing
- No Bolus, Alternate Bolus, Continuous Bolus
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- AC Camargo Cancer Center
Breast Cancer
Mirtazapine for Acute and Chronic Post Mastectomy Pain
Our aim in this study will be to investigate the effect of mirtazapine on acute post-mastectomy pain manifested by total morphine consumption in first 24 hours and VAS score at rest and movement (primary outcomes).
- Trial name
- NCT06499090
- Testing
- Mirtazapine 30 MG
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Neuropathic Pain
Memantine and Post-mastectomy Neuropathic Pain
The aim of this study is to evaluate if memantine administered for four weeks starting two weeks before surgery induces a decrease in pain intensity at 3 months post-mastectomy.
- Trial name
- CLEMANTINE (NCT03686774)
- Testing
- Memantine, no memantine
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Clermont-Ferrand
Lymphocele
Use of Compression Bandages in the Prevention of Post-mastectomy Lymphoceles
Lymphocele secondary to a mastectomy whether or not associated with a lymph node procedure (sentinel lymph node or axillary dissection) is an almost systematic consequence observed in the postoperative situation in this type of…
- Trial name
- BANDOCELE (NCT04819542)
- Testing
- Bandage, No bandage
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Toulouse
Post-mastectomy Pain Syndrome, Myofascial Pain Syndrome
Trigger Point Injections for Post-Mastectomy Pain Syndrome
Post-Mastectomy Pain Syndrome (PMPS) is a chronic pain that persists for more than three months after a surgical breast procedure. It has 11-70% incidence in patients that underwent a breast surgery.
- Conditions
- Post-mastectomy Pain Syndrome, Myofascial Pain Syndrome, Trigger Point Pain, Myofascial, Breast Cancer
- Trial name
- NCT04267315
- Testing
- Trigger point injection, Subcutaneous saline injection, Comprehensive Rehabilitation program
- Where
- 2 sites in Brazil
- Volunteers
- 72 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Post-Mastectomy Chronic Pain Syndrome
Radiofrequency Thoracic Sympathectomy for Chronic Postmastectomy Pain; Randomized Placebo Controlled Study
Postmastectomy pain syndrome (PMPS) is a neuropathic pain that can follow surgical treatment for breast cancer, The antineuropathic medications (antidepressants and anticonvulsants) are disappointing and have low success rate.
- Trial name
- NCT03494426
- Testing
- radiofrequency thoracic sympathectomy, pregabalin ,tramadol,and tricyclic antidepressants
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Dexmedetomidine, Lidocaine
Dexmedetomidine Versus Lidocaine Infusions as Adjuvants to General Anesthesia for Chronic Pain Management After Mastectomy
This study aims to compare dexmedetomidine and lidocaine infusions as adjuvants to general anesthesia for chronic pain management after mastectomy.
- Conditions
- Dexmedetomidine, Lidocaine, Infusion, Adjuvants
- Trial name
- NCT06910644
- Testing
- Dexmedetomidine, Lidocaine, Isotonic saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Breast Carcinoma
Hypofractionated Post Mastectomy Radiation With Two-Stage Expander/Implant Reconstruction
Hypofractionated radiotherapy could provide more convenient treatment and had similar toxicities.However,reports of hypofractionated radiotherapy with two-stage expander/implant reconstruction are rare,Some studies have shown…
- Trial name
- NCT05045287
- Testing
- hypofractionated radiotherapy
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Chinese Academy of Medical Sciences