Clinical trials: Post-Operative Condition
Rhinoplasty, Edema
Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre
This single-centre, randomized, double-blind, sham-controlled clinical trial evaluates whether preoperative photobiomodulation (PBM) with red and infrared light can reduce early postoperative periorbital edema in patients…
- Trial name
- NCT07033039
- Testing
- Photobiomodulation, Simulation of Photobiomodulation, Standard treatment protocol
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Postoperative Complications
4-choice Reaction Time Test for the Measurement of Psychomotor Recovery After General Anaesthesia
The recovery of patients after general anaesthesia is usually estimated by using clinical signs and scores. Since there is a lack of the agreed objective methods for assessing cognitive and psychomotor recovery after general…
- Trial name
- 4CRT_Ane (NCT03697057)
- Testing
- General anaesthesia
- Where
- Germany
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Colorectal Disorders, Incisional Hernia
Incisional Hernia and Adhesion-Related Bowel Obstruction
Despite of technological advances in surgery, incisional hernia and bowel obstruction remain frequent surgical complications. To date, the relationship between these two types of surgery and the occurrence of incisional hernia…
- Conditions
- Colorectal Disorders, Incisional Hernia, Bowel Obstruction
- Trial name
- NCT02116881
- Testing
- Colorectal Surgery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Obstructive Sleep Apnea, Postoperative Pain
Effect of Sleep Apnea on Pain After Dental Treatment
This observational study aims to investigate the effects of sleep quality and systemic health status on pain levels following endodontic treatment in adult patients.
- Conditions
- Obstructive Sleep Apnea, Postoperative Pain, Hypertension Complicated With Type 2 Diabetes
- Trial name
- OSA-EndoPain (NCT07581964)
- Testing
- Standard Endodontic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Harran University
Pain, Acute Postoperative
Comparison Of Outcome Of Wound Closure After Thyroid Surgery With And Without Platysma Suturing
Comparison Of Outcome Of Wound Closure After Thyroid Surgery With And Without Platysma Suturing in terms of wound scar and pain.
- Trial name
- NCT06485011
- Testing
- Paltysma suturing, Without Platysma suturing
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Emergence Delirium, Anesthesia
Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children
This is a clinical study for comparing the efficacy of two drugs i.e propofol and dexmedetomidine in prevention of a group of post operative abnormal behaviours that can occur after sevoflurane anesthesia in children and we will…
- Trial name
- NCT07799311
- Testing
- propofol 1mg/kg, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Neuromuscular Blocking Agents, Urinary Retention After Procedure
NMBA Reversal and Postoperative Urinary Retention
In this single-center retrospective cohort study of adult patients who underwent surgery under general anesthesia at Beth Israel Deaconess Medical Center between September 2016 and January 2024, the association between the choice…
- Conditions
- Neuromuscular Blocking Agents, Urinary Retention After Procedure, Urinary Retention Postoperative, Neuromuscular Blockade Reversal Agent
- Trial name
- NCT06948409
- Testing
- Choice of reversal agent (sugammadex or neostigmine [with muscaranic antagonist])
- Where
- United States
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Prevention
Intravenous Versus Intraperitoneal Instillation of Ondansetron for Decreasing Incidence of Nausea and Vomiting After Laparoscopic Gynecological Surgeries.
Study the effect of intraperitoneal instillation vs intravenous ondansetron on PONV added to intraperitoneal bupivacaine for enhanced recovery and to decrease incidence of PONV after laparoscopic surgeries.
- Trial name
- NCT05317611
- Testing
- Intraperitoneal instillation of ondansetron and bupivacaine, Intravenous ondansetron and intraperitoneal instillation of bupivacaine, Intraperitoneal instillation of bupivacaine
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Post Operative Pain, Opioid Side Effects
Find the Adequate Dose of Nalbuphine for Laparoscopic Cholecystectomy
This study evaluate the adequate dose of mutonpain for laparoscopic cholecystectomy in the management of post operative pain. The investigators will randomize patients into three groups to compare the analgesia effects and side…
- Trial name
- NCT04135534
- Testing
- group A, group B, group C
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Intrauterine Abnormalities in Infertility, Asherman Syndrome
Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion
The aim of this study was to obtain short- and long-term performance and safety data of cross-linked hyaluronic acid-based adhesion barrier gel used to prevent intrauterine adhesion formation.
- Conditions
- Intrauterine Abnormalities in Infertility, Asherman Syndrome, Intra-uterine Adhesions, Postoperative Adhesion of Uterus
- Trial name
- SEMFERTIL (NCT07160764)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Thyroid Cancer, Breast Cancer
Dexamethasone Reduces Postoperative Emesis by Decreasing PGF2α and LTC4 Levels
Hypothesis: Dexamethasone reduces postoperative emesis in thyroidectomy and mastectomy patients.
- Trial name
- NCT01811199
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Postoperative Pain
Erector Spinae Plan Block for Postoperative Analgesia
Laparoscopic cholecystectomy is a widely employed procedure in ambulatory surgery. Pain after laparoscopic cholecystectomy arises significantly from port site incisions in the anterior abdominal wall.
- Trial name
- NCT03398564
- Testing
- Erector Spinae Plan Block, Oblique subcostal TAP
- Where
- Saudi Arabia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Acute Pain, Postoperative Pain, Acute
REctus Sheath Trial
Regional anesthesia techniques (or nerve blocks) are used to provide sensory blockade over the abdominal wall. The most established technique is thoracic epidural.
- Trial name
- REST (NCT07068243)
- Testing
- 1.0% lidocaine with epinephrine (1:100,000)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Postoperative Pain, Wisdom Tooth
Protective Analgesia for Postoperative Pain Relief Following Day Case Oral Surgery
The purpose of this study is to investigate whether robust analgesic regime (protective analgesia) can improve postoperative pain experience for patients undergoing lower wisdom teeth extraction under day case general anaesthetic.
- Trial name
- NCT00895843
- Testing
- Brufen retard, ibuprofen, Bupivacaine
- Where
- 2 sites in United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Ankle Fractures, Pain, Postoperative
Ropivacaine Versus Bupivacaine as Preemptive Analgesia in Surgical Site in Ankle Fracture Patients
Title: Ropivacaine versus Bupivacaine as Preventive Analgesia in Surgical Incision Site In Patients With Ankle Fracture Background: Ankle fractures are about 10% of the fractures associate to sports and with an incidence of 0.11…
- Conditions
- Ankle Fractures, Pain, Postoperative, Local Infiltration
- Trial name
- NCT02949674
- Testing
- Ropivacaine, Bupivacaine
- Where
- Mexico
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Thyroid Cancer, Thyroid Nodule
Educational Videos for Thyroid Surgery Patient
The researchers aim to evaluate the performance of two groups of participants after receiving traditional education-one group supplemented with video-based education and the other without.
- Conditions
- Thyroid Cancer, Thyroid Nodule, TSH, Education of Patients
- Trial name
- NCT07823543
- Testing
- Thyroid Surgery Educational Video
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Liver Cirrhoses, Chronic Pancreatitis
Malnutrition in Chronic Gastrointestinal Diseases, Cross-sectional Study
Malnutrition and muscle wasting are common consequences of life-threatening, chronic diseases of the gastrointestinal tract. Such diseases include liver cirrhosis, chronic pancreatitis and short bowel syndrome.
- Conditions
- Liver Cirrhoses, Chronic Pancreatitis, Short Bowel Syndrome
- Trial name
- NCT04474743
- Testing
- No intervention - cross-sectional observational only
- Where
- 3 sites in Germany
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Postoperative Care, Pain Management
Effectiveness of Curcuminoids in Controlling Postoperative Pain Following Total Laparoscopic Hysterectomy
Total hysterectomy is one of the most common surgical procedures in gynecology. Total laparoscopic hysterectomy (TLH) has several advantages over open surgery, such as better cosmetic outcomes, faster recovery, and an earlier…
- Trial name
- NCT06886035
- Testing
- liposomal curcumin
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Endodontic Disease
Effect of Different Irrigation Solutions on Postoperative Pain and Lesion Healing
In this study researchers plan to conduct, three different irrigation solutions that are responsible for the release of growth factors necessary for the success of regenerative endodontic treatments will be used.
- Trial name
- NCT06386991
- Testing
- Using ethylenediaminetetraacetic acid (EDTA), citric acid ((MONO/ANH) and etidronic acid (HEBP) to clean root canals during regenerative endodontic treatments
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Laparoscopic Surgery, Herniorrhaphy
Comparison the Analgesic Efficacy of Ultrasonographic Bilateral TAP and Anesthetic Infiltration Into the Surgery Field for Laparoscopic Unilateral TEP Herniorrhaphy
Laparoscopic inguinal hernia repair is a common surgical procedure, but postoperative pain management remains a challenge. This prospective, randomized study aims to compare the analgesic efficacy of preperitoneal and surgical…
- Conditions
- Laparoscopic Surgery, Herniorrhaphy, Inguinal Hernia Unilateral, Transversus Abdominis Plane (TAP) Block
- Trial name
- NCT06894420
- Testing
- Surgeon-Initiated Local Anesthetic, Transversus abdominis plane (TAP) block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
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