Clinical trials: Post-Operative Condition
Postoperative Atelectasis, Postoperative Pulmonary Atelectasis
Lung Ultrasound Assessment of Postoperative Atelectasis After Mechanical Ventilation With Minimum Driving Pressure
Brief summary The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure…
- Conditions
- Postoperative Atelectasis, Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications (PPCs), Lung Ultrasonography Score
- Trial name
- NCT07186920
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Total Knee Replacement, Post Operative Pain
Effect of Mindfulness on Pain After Total Knee Arthroplasty
This study will be a prospective randomized controlled trial evaluating the effectiveness of using Headspace before and after undergoing total knee replacement surgery.
- Conditions
- Total Knee Replacement, Post Operative Pain, Opioid Use
- Trial name
- NCT06118073
- Testing
- Headspace, Total Knee Replacement
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Procedural Sedation, Emergence Delirium
Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine
The purpose of this study is to determine if positive imagery therapy while using ketamine in procedural sedation reduces the number of emergence reactions and impacts pre and post-procedural anxiety.
- Trial name
- NCT04746079
- Testing
- Positive Imagery Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Urologic Surgical Procedures, Urinary Bladder, Neurogenic
Pediatric Urology Recovery After Surgery Endeavor (PURSUE)
The purpose of this research study is to evaluate an Enhanced Recovery After Surgery (ERAS) protocol in children and young adults undergoing urologic reconstructive surgery.
- Conditions
- Urologic Surgical Procedures, Urinary Bladder, Neurogenic, Urinary Bladder Diseases
- Trial name
- NCT03245242
- Testing
- Enhanced Recovery after Surgery, Historical usual surgical care
- Where
- 7 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Oxygen, Postoperative Nausea and Vomiting
The Effect of Oxygen Given to Patients in the Postoperative Period on Nausea and Vomiting
Carbon dioxide which is insufflated to inflate the abdominal area is absorbed from the peritoneal area and it increases endogenous catecholamines, which may consequently increase nausea and vomiting.
- Trial name
- NCT04597723
- Testing
- oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Phantom Limb Pain, Phantom Pain
Perioperative Mirror Therapy and Phantom Limb Pain
Mirror therapy will consist of observing the unaffected limb reflected in a mirror positioned in the midline to block the view of the affected limb.
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Pseudomelia
- Trial name
- NCT02383979
- Testing
- Mirror
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Post Operative Pain
Postoperative Pain After Using Different Single-File Glide Path Systems
This study aimed to evaluate postoperative pain intensity after glide-path preparation with the ProGlider (PG) and WaveOne Gold Glider (WOGG) systems in asymptomatic teeth with necrotic pulp and periapical lesions.Maxillary and…
- Trial name
- NCT05955742
- Testing
- Control, ProGlider, WaveOne Gold Glider
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Osteoarthritis
Comparison of Anesthetic Techniques on Total Hip Arthroplasty
To compare analgesia and orthopedic rehabilitation milestones in patients receiving either spinal anesthesia (local anesthetic plus opioid) or general endotracheal anesthesia with lumbar plexus block.
- Trial name
- NCT01359865
- Testing
- Lumbar Plexus Block
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Post Operative Pain
Effect of Ascorbic Acid Final Flush on Post-operative Pain in Mandibular Molars.
The study is conducted to evaluate the effect of Ascorbic acid as a final flush on post operative pain after single visit root canal treatment in cases with symptomatic irreversible pulpits.
- Trial name
- NCT05478044
- Testing
- Ascorbic acid, saline
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain
Opioid Analgesic Reduction Study (OARS) - Pilot
The purpose of this study is to test protocols being developed for the conduct of a large sale multi-site clinical trial which will compare opioids to non-opioids for managing post-surgical impacted 3rd molar extraction pain.
- Trial name
- OARS-Pilot (NCT05283499)
- Testing
- OPIOID, NON-OPIOID
- Where
- 5 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Post-operative Pain
Reduction of Pain Following Laparoscopic Surgery: A Double Blind Prospective Randomized Controlled Trial
Shoulder tip and abdominal pain following laparoscopic procedures are well recognized as causes of post-operative morbidity. This prospective, double-blind, randomized controlled trial attempts to reduce post-operative pain in…
- Trial name
- NCT01720433
- Testing
- intervention
- Where
- United Kingdom
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Northampton General Hospital NHS Trust
Root Canal Sealers, Post Operative Pain
Evaluation of Post Obturation Pain Associated With Calcium Hydroxide-based Root Canal Sealers and Resin-based Root Canal Sealer: a Single Visit Root Canal Treatment
The objective of this study is to evaluate the post obturation pain associated with calcium hydroxide-based root canal sealer and resin-based root canal sealer after single visit root canal treatment following endodontic…
- Conditions
- Root Canal Sealers, Post Operative Pain, Irreversible Pulpitis
- Trial name
- NCT06798467
- Testing
- Endodontic sealer, post obturation pain
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jinnah Sindh Medical University
Edema, Perioperative/Postoperative Complications
Body Composition and Serum Biochemistry After Intravenous Infusion or Oral Intake of Saline in Healthy Volunteers
The investigators conducted a cross-over study to compare the response of healthy young volunteers to a rapid oral intake or intravenous infusion of 0.9% saline solution on the body composition, serum electrolytes, albumin, and…
- Trial name
- NCT01539798
- Testing
- Oral saline, Intravenous saline
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Postoperative Pain
Magnesium Sulfate on Postoperative Pain
Breast cancer is the most diagnosed type of cancer in women in Turkey and in the world. According to the World Health Organization data, the rate of newly diagnosed breast cancer was reported as 11.6% in 20181.
- Trial name
- NCT05880732
- Testing
- Magnesium Sulfate, normal saline isotonic solution
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Hemorrhoidectomy, Third Degree Hemorrhoids
Hemorrhoidectomy in Patients With Grade III and IV Disease:Harmonic Scalpel Compared With Conventional Technique
Hemorrhoidectomy is the treatment of choice for grade 3 and 4th degree hemorrhoids. Various surgical technique has been used to improve the outcome of the procedures performed in respect to operative time ,post operative pain and…
- Conditions
- Hemorrhoidectomy, Third Degree Hemorrhoids, Fourth Degree Hemorrhoids, Operative Time
- Trial name
- NCT03938714
- Testing
- Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Services Hospital, Lahore
Chemotherapy, Colorectal Cancer
Zinc Supplementation on Markers of Oxidative Stress in Post Operative Colorectal Cancer During Chemotherapy Cycles
Objective: To determine the oxidative stress during cycles of chemotherapy in patients after surgery for colorectal cancer, with or without oral zinc supplementation.
- Trial name
- NCT02106806
- Testing
- Zinc
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Vital Pulp Therapies, Pulpotomy
Comparison of Sodium Hypochlorite Gel and Solution With and Without Nanoparticles for Postoperative Pain After Pulpotomy in Permanent Mandibular Molars
This randomized clinical trial aims to compare the effect of 2% sodium hypochlorite gel and solution, with and without chitosan nanoparticles, on postoperative pain following pulpotomy in mature permanent mandibular molars with…
- Conditions
- Vital Pulp Therapies, Pulpotomy, Irriversible Pulpitis, Postoperative Pain
- Trial name
- NaOCl Pulpotom (NCT07774130)
- Testing
- Sodium Hypochlorite gel 2%, Sodium hypochlorite gel 2% with chitosan nano particles, Sodium hypochlorite solution 2% with chitosan nanoparticles
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Endodontic Disease, Post Operative Pain
Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
This study will assess the efficacy of two local anesthetics (2% lidocaine 1:100,000 epinephrine and 0.5% bupivicaine 1:200,000 epinephrine) in reducing post-operative pain in patients receiving endodontic treatment.
- Conditions
- Endodontic Disease, Post Operative Pain, Symptomatic Irreversible Pulpitis
- Trial name
- NCT05338671
- Testing
- Local anesthetic
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Washington
Apical Periodontitis, Assessment, Pain
Reciprocation vs Rotational Single-file Systems in Postoperative Pain
In this study, the researchers will investigate the effect of single-file reciprocating versus single-file rotational file systems on the postoperative pain in adult patients who have necrotic pulp and apical periodontitis.
- Conditions
- Apical Periodontitis, Assessment, Pain, Dental Pulp Necrosis
- Trial name
- NCT02929511
- Testing
- Reciprocating single-file system, Rotational single-file system., Active comparator Protaper multi-file system
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Isparta Military Hospital
Chronic Pain
A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children
The purpose of this study is to investigate the prevalence, risk factors and consequences of chronic post-surgical pain in children aged 0-16 years through a number of questionnaires completed at various timepoints, from before…
- Trial name
- POPSICLE (NCT06354699)
- Where
- 16 sites in United States, Australia and 2 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Telethon Kids Institute