Clinical trials: Post-Operative Condition
Postoperative Cognitive Dysfunction, Delirium
Cohort Study to Investigate the Association Between Changes in Brain Volume and Postoperative Cognitive Dysfunction
Despite an ongoing controversy in the scientific literature, the link between anesthesia and dementia and/or cerebral atrophy remains unclear.
- Conditions
- Postoperative Cognitive Dysfunction, Delirium, Dementia
- Trial name
- POCD-MRI (NCT02045004)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nicolai Goettel
Cesarean Section, Adhesions
Closure of Peritoneum at Cesarean Section and Postoperative Adhesion
Objective: To determine the effect of non-closure of the visceral and parietal peritoneum during Cesarean section on the formation of adhesions.
- Trial name
- cs adhesions (NCT01183000)
- Testing
- Closure of the peritoneum at cs
- Where
- 2 sites in Israel
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Short Bowel Syndrome
Safety and Immunogenicity of Rotavirus Vaccine (RotaTeq(R)) in Infants With Short Bowel Syndrome
Rotavirus infection is a common pediatric illness and is the leading cause of severe acute gastroenteritis (vomiting and diarrhea) in infants and young children.
- Trial name
- NCT00767364
- Testing
- Oral, live, pentavalent rotavirus vaccine; RotaTeq(R)
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Michigan
Postoperative Complications
To Compare the Incidence of POST Between a TaperGuard ETT and Cylindrical-shaped ETT Under High Cuff Pressure
Postoperative Sore Throat (POST) is supposed to be the most frequently occurred respiratory complication related to endotracheal intubation .Whether the new type of ETT(TaperGuard ETT) to decrease or to increase the complications…
- Trial name
- NCT02666300
- Testing
- TaperGuard ETT
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Dalian Medical University
Hernia, Pain, Postoperative
Pilot Study: Rectus Sheath Blocks for Improving Abdominal Surgery Conditions
The purpose of this study is to show that the use of preoperative rectus sheath blocks can ultimately alleviate the need for using nondepolarizing muscle relaxants during certain abdominal procedures.
- Conditions
- Hernia, Pain, Postoperative, Abdominal Wall Relaxation After Rectus Sheath Block
- Trial name
- NCT02447965
- Testing
- Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Postoperative Pain
Extended Release Local Anesthetic for Postsurgical Pain After Posterior Colporrhaphy and Perineorrhaphy
The specific aim of this randomized double-blind clinical trial is to evaluate the effect of intraoperative infiltration of liposomal bupivacaine at the time of posterior colporrhaphy and/or perineorrhaphy on postsurgical pain…
- Trial name
- NCT03875664
- Testing
- Liposomal bupivacaine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Post Operative Nausea and Vomiting, Rescue Emetic Therapy
Rescue Emetic Therapy for Children Having Elective Surgery
To compare ondansetron, metoclopramide, diphenhydramine, and placebo in order to determine which anti-emetic is most efficacious as a "rescue therapy" for pediatric patients ages 3-18 who have post-operative vomiting after a…
- Trial name
- RETCHES (NCT01067677)
- Testing
- Metaclopramide, Ondansetron, diphenhydramine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Franklyn Cladis
Elective Laparoscopic Cholecystectomy
The Effect of Respiratory Exercises on Abdominal Distension in Laparoscopic Cholecystectomy Patients
Laparoscopic cholecystectomy is the first-line treatment for symptomatic gallstones. Pneumoperitoneum is the process of expanding the abdominal cavity during the surgical procedure by introducing CO2 gas into the abdomen to widen…
- Trial name
- NCT06069557
- Testing
- Respiratory exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Delirium
Rate of Postoperative Delirium and Postoperative Cognitive Dysfunction After Spinal Anesthesia
The aim of this investigation is to compare the standard of general anesthesia used in these patients with these short-acting local anesthetics (Chloroprocain (Ampres®) and Prilocain (Takipril®)) for spinal anesthesia as well as…
- Trial name
- NCT03715244
- Testing
- Spinal anesthesia with short-acting local anesthetics, General anesthesia (current standard)
- Where
- Germany
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Postoperative Pain
Open-Label Safety and Tolerability Study of Oxymorphone for Acute Postoperative Pain in Pediatric Subjects.
When post-operative parenteral analgesia is discontinued, oral dosing with study medication may begin once the subject has developed a moderate level of pain as defined by a 100 mm VAS (pain intensity score greater than or equal…
- Trial name
- NCT00801398
- Testing
- Oxymorphone IR
- Where
- 11 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Prosthesis Durability
Ultrasound Investigation of Tongue Movement for Implant Overdenture
This study aimed to examine the impact of mandibular implant overdentures on tongue movement during mastication.
- Trial name
- NCT06705114
- Testing
- complete denture, implant overdenture
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Misadventure During Surgical Operation, Postoperative Complications
Trendelenburg's Slide Prevention Study
The purpose of this study is to compare two cushioning materials (a gel mattress and an egg-crate foam mattress) placed beneath patients undergoing gynecologic surgery to prevent patients from sliding toward the head of the bed…
- Trial name
- SPS (NCT01068821)
- Testing
- Gel pad, Egg crate foam mattress
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Symptomatic Apical Periodontitis
Postoperative Pain and Substance P Levels After Bioceramic vs Calcium Hydroxide Intracanal Medicaments in Symptomatic Apical Periodontitis
Clinical Evaluation of the Postoperative Pain and Substance P levels Following the use of Bioceramic verses Calcium Hydroxide Intracanal Medicaments in Permanent Mandibular molars with Symptomatic Apical Periodontitis
- Trial name
- (BCvsCaOH) (NCT07585721)
- Testing
- Calcium Hydroxide (Ca(OH)2), Bioceramic Intracanal Medicament
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Surgical Wound Infection
The Use of a Silver Containing Dressing (Acticoat) on Wound Complication Rates Post Elective Cesarean Section
The purpose of this study is to determine the effect of a silver containing dressing (Acticoat Post-Op) compared to a standard dressing (OpSite PostOp) on post elective cesarean section wound complications in obese women (BMI…
- Trial name
- NCT02288884
- Testing
- Acticoat PostOp, OpSite PostOp
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Pain, Referred
Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section
The purpose of this study is to determine if giving an injection of numbing medication at the incision at the end of cesarean will help control pain AFTER cesarean delivery.
- Trial name
- NCT03383588
- Testing
- Bupivacaine, Morphine, Fentanyl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Auricular Acupressure, Cervical Spine Surgery
Auricular Acupressure on Improving Pain and Heart Variability in Patients After Cervical Spine Surgery
The primary objective of this study is to investigate the effectiveness of auricular acupressure in improving post-cervical spine surgery pain and heart rate variability in patients.
- Trial name
- NCT06087380
- Testing
- auricular acupressure, standard ward care
- Where
- Taiwan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Surgical Site Infection, Complication of Surgical Procedure
Topical Antibiotics in Surgical Site
Ankle fractures are one of the most common injuries in traumatology. It is the fourth most common fracture in general population after hip, wrist, and hand fractures.
- Trial name
- NCT05363462
- Testing
- Vancomycin 1000 MG
- Where
- Mexico
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Postoperative Pain, Erector Spinae Plane Block in Spinal Surgery
Open Technique Erector Spinae Plane Block in Spinal Surgery
Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.ESPB has been successfully applied as a part of multimodal analgesia in treating postoperative pain…
- Trial name
- NCT06157762
- Testing
- Erector spinae plane block, Erector spinae plane block performed by surgeon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Pain, Postoperative
Rhomboid Intercostal Block Compared With Thoracic Paravertebral Block in Breast Cancer Surgeries
Postoperative pain is a significant problem following breast surgery . If not treated in time, it may lead to delayed wound healing, respiratory depression, hemodynamic disorders, anxiety,other complications, and finally lead to…
- Trial name
- NCT06781346
- Testing
- Rhomboid Intercostal Block, Thoracic Paravertebral Block
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Postoperative Pain
Preemptive Use of the Nicotine Patch for Postoperative Pain Relief After Open Abdominal Surgery
The efficacy of a low dose nicotine patch of seven milligrams placed before surgery and its effect on decreasing pain after surgery is the main purpose of the study.
- Trial name
- NCT00790829
- Testing
- transdermal nicotine patch
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stony Brook University