Clinical trials: Post-Operative Condition
Post Operative Pain
Laparoscopic-guided TAP Block vs Epidural Analgesia
The LAPTAP trial will provide evidence on preferred post-operative analgesia method in elective laparoscopic colon surgery.
- Trial name
- NCT05214261
- Testing
- Safety and efficiency of post operative analgesia between laparoscopic-assisted TAP block and epidural analgesia
- Where
- Finland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome
Paravertebral Versus Pectoralis Block for Post Mastectomy Pain
Post-mastectomy pain affects more than half of patients undergoing the procedure and can last for years. It has been well established that development of chronic pain is related to experienced pain in the perioperative period.
- Conditions
- Pain, Postoperative, Post-Mastectomy Chronic Pain Syndrome, Opioid Use
- Trial name
- NCT03656679
- Testing
- Pectoralis Blockade (PECs), Paravertebral Blockade
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cognitive Impairment, Postoperative Delirium
Cognitive Impairment Following Elective Spine Surgery
Older people are a rapidly growing proportion of the world's population and their number is expected to increase twofold by 2050.
- Conditions
- Cognitive Impairment, Postoperative Delirium, Spine Fusion
- Trial name
- CONFESS (NCT03486288)
- Where
- Germany
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Phantom Limb Pain
Electrical Stimulus Therapy for Chronic Phantom Limb Pain
The goal of this pilot study is to assess the effectiveness of an electrical stimulation therapy option for the treatment of chronic phantom limb pain in upper or lower limb amputees.
- Trial name
- NCT03030079
- Testing
- Experimental Electrical Stimulation Regimen
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Stress Urinary Incontinence, Postsurgical Pain
The Follow-up After Shorter Tapes Study. Effectiveness and Safety of Shorter Trans-obturator Tapes.
Urinary incontinence after pregnancy and labor affects 1 in 3 women and has a negative impact on quality of life (QOL), limiting women's physical activity and impairing sexual function.
- Conditions
- Stress Urinary Incontinence, Postsurgical Pain, Follow-Up Studies
- Trial name
- FAST (NCT06731985)
- Where
- Norway
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Osteoarthritis, Degenerative Joint Disease
Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement
The purpose of this study is to clarify the efficacy of a multidrug versus single drug periarticular injection when only standard operative and postoperative pain management protocols used and the control group is exposed to what…
- Trial name
- NCT03119038
- Testing
- Bupivicaine + epinephrine, Bupivacaine, Ropivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Gynecologic Neoplasm, Healthy Women
The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled Trial
The aim of this clinical trial is to learn if Dimenhydrinate works to prevent postoperative nausea-vomiting in adult women who undergoing abdominal hysterectomy.
- Trial name
- NCT06395064
- Testing
- Dimenhydrinate
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Preeyaporn Jirakittidul
Thumb Joint Stiffness
Electrical Stimulation to Recover Greater Range of Motion After Surgery
Background One of the potentially debilitative complications of operative repair and subsequent immobilization is stiffness that appears secondary to inflammation and adhesions.
- Trial name
- NCT01082432
- Testing
- electrically induced muscle activation
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université Joseph Fourier
Complication, Postoperative, Perioperative/Postoperative Complications
The Impact of Prehabilitation Bundle on Perioperative Outcome for Frail Elderly Patients Undergoing Major Abdominal Surgery
This study aims to study the efficacy of a preoperative "bundle" of interventions, which consists of preoperative physiotherapy, nutritional support and cognitive exercises on elderly frail patients undergoing major abdominal…
- Trial name
- NCT02921932
- Testing
- Ensure, Resource 2.0 and Glucerna, Cognitive Training, Memory Card Game, 'Threshold' Inspiratory Muscle Trainer, Respironics of New Jersey Inc
- Where
- Singapore
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Impacted Third Molar Tooth, Impacted Molar
Different Oral Doses of Clindamycin in Preventing Post-operative Sequelae of Lower Third Molar Surgery
The objective of the study is to determine the effect of antibiotic prophylaxis with three different doses of clindamycin on preventing infection and other complications after surgical extraction of impacted mandibular third…
- Trial name
- NCT05268835
- Testing
- Dalacin C
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oral and Maxillofacial Surgery Clinic, Poland
Pain, Post Operative Pain
Erector Spinae Plane Block for Postoperative Pain Management
Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.
- Trial name
- NCT05697315
- Testing
- Control, Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Hypothermia, Postoperative Pain
Optimal Temperature Control in Body Contouring Procedures
The goal of this clinical trial is to compare different strategies for normothermia prevention in patients undergoing body contouring and other Aesthetic Plastic Surgery procedures.
- Conditions
- Hypothermia, Postoperative Pain, Postoperative Nausea, Postoperative Complications
- Trial name
- NCT06238739
- Testing
- Control - Standard Strategies for hypothermia prevention, Fluid warming before infusion and infiltration, Thermal convection blanket by water flow (Blanketrol)
- Where
- Colombia
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Surgical Site Infection
Using mHealth Technology to Identify and Refer Surgical Site Infections in Rwanda
The present study aims to examine whether or not the use of mobile Health (mHealth) by community health workers (CHWs) can improve the identification of surgical site infection (SSI) and a timely return to care among patients who…
- Trial name
- NCT03311399
- Testing
- SSI Screening Tool used in home visits by CHWs, SSI Screening Tool used via phone call follow-up
- Where
- Rwanda
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Anesthesia, Analgesia
Genetic Variants and Perioperative Morbidity and Mortality
Prospective association study to analyse perioperative patients' outcome. Outcome comprises intraoperative and postoperative complications e.g.
- Conditions
- Anesthesia, Analgesia, Surgical Procedure, Operative
- Trial name
- NCT02124499
- Where
- Switzerland
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Mandibular Premolars and Canines With Asymptomatic Apical Periodontitis
The Effect of Different Irrigation Methods Used During Endodontic Treatment on Postoperative Pain in Teeth With Periapical Lesions
The aim of this study is to evaluate the effect of different irrigation activation methods used during endodontic treatment on postoperative pain in teeth with periapical lesions, allowing us to clinically determine which…
- Trial name
- NCT07410832
- Testing
- Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Post Operative Pain
Comparison Between Two Blocks in Analgesia After Knee Arthroplasty
Comparative Study between Adductor canal block combined with infiltration OF The interspace between popliteal artery and the capsule of the knee block versus genicular nerves Block combined with IPACK in Postoperative analgesia…
- Trial name
- NCT07046377
- Testing
- ACB - IPACK, GNB - IPACK
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Liver Cancer, Esophageal Cancer
Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease…
- Conditions
- Liver Cancer, Esophageal Cancer, Colorectal Cancer, Lung Adenocarcinoma
- Trial name
- TEG (NCT05517811)
- Testing
- TEG indices
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postoperative Nausea and Vomiting
Sugammadex Versus Neostigmine for Postoperative Nausea and Vomiting After Laparoscopic Gynaecological Surgery
The laparoscopic technique is commonly employed for abdominal gynaecological surgery in women. Postoperative nausea and vomiting (PONV) may occur in 30% of women undergoing gynaecological surgery.
- Trial name
- NCT02666014
- Testing
- Sugammadex, Neostigmine
- Where
- Singapore
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Delirium, Cognitive Disorders
Anesthetic Depth and Postoperative Delirium Trial - 2
Recent limited evidence suggests that anesthetic depth may influence postoperative cognitive outcomes, however, the mechanism between this association is unclear.
- Trial name
- ADAPT2 (NCT01983384)
- Testing
- Processed EEG-guided anesthetic depth
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Postoperative Pain
Postoperative Pain Therapy With Hydromorphone Using TCI-PCA
Treatment of postoperative pain with hydromorphone (a strong analgesic) using patient-controlled analgesia with target concentrations in blood compared to conventional patient-controlled analgesia after planed cardiac surgery
- Trial name
- TCI-PCA (NCT02035709)
- Testing
- Hydromorphone
- Where
- 2 sites in Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
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