Clinical trials: Post-Operative Condition
Central Line Complication, Central Line Infection
Innovative Central Line Securement Device in the Pediatric Population
This study involves evaluating pediatric patients with central lines to determine differences in line complications and quality of life in those with a novel central line securement device (wrap) as compared to those who use a…
- Conditions
- Central Line Complication, Central Line Infection, Central Line-Associated Infection, Central Line Sepsis
- Trial name
- NCT04522778
- Testing
- Wearable Central Line Securement Device (Vest), Traditional Securement Dressing
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Ryan St. Pierre-Hetz
Ventral Hernia, Hernia
Pilot Trial of Abdominal Core Rehabilitation To Improve Outcomes After Ventral Hernia Repair
This study aims to evaluate the potential role of physical therapy in improving outcomes after ventral hernia repair.
- Conditions
- Ventral Hernia, Hernia, Herniorrhaphy, Abdominal Wall
- Trial name
- ABVENTURE-P (NCT05142618)
- Testing
- Supervised Physical Therapy, Post-operative Precautions
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Ohio State University
Emergence Agitation
The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children
The purpose of this study is to determine whether depth of anesthesia has an effect on emergence agitation (EA) in children age 2 - 8 years old.
- Trial name
- NCT00990769
- Testing
- Depth of anesthesia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Venous Thromboembolism
Prospective Study on Preoperative Versus Postoperative Venous Thromboprophylaxis in Patients Undergoing Major Colorectal Surgery
Patients undergoing major colorectal surgery are at increased risk for VTE (deep venous thrombosis) compared with patients undergoing other general surgical procedures (Bergqvist et al. Dis. Col. Rectum.
- Trial name
- NCT01976988
- Testing
- Heparin
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- Cedars-Sinai Medical Center
Pressure Ulcer, Ankle, Prosthesis User
Limb Health and Socket Pressure in Response to Powered Ankle Protheses
this project seeks to understand and quantify the effects of powered transtibial prostheses on socket loading and direct measures of residual limb health so as to inform the optimization of prosthesis fit.
- Conditions
- Pressure Ulcer, Ankle, Prosthesis User, Prosthesis Durability, Mobility Limitation
- Trial name
- OPORP (NCT05112679)
- Testing
- PROPRIO FOOT® by Ossur & Empower ankle by Ottobock
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Indiana University
Phantom Limb Pain
Mixed Reality Based System to Manage Phantom Pain Phantom Pain for Patients With Lower Limb Amputation
The primary goals of this pilot research project are a) to design and develop the a mixed reality based system for managing phantom pain and b) to evaluate the feasibility and preliminary functional outcomes of this system in a…
- Trial name
- MrMAPP (NCT04529083)
- Testing
- Mr. MAPP
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Dallas VA Medical Center
Bunions, Postoperative Pain
Dose-Escalation Study of HTX-034 Following Bunionectomy
This was a Phase 1b/2, randomized, blinded, active-controlled study. Phase 1b evaluated escalating doses of HTX-034 compared with bupivacaine HCl.
- Trial name
- NCT04398329
- Testing
- HTX-034 low dose, HTX-034 high dose, Luer lock applicator
- Where
- 4 sites in United States
- Volunteers
- 78 people
- Sponsor
- Heron Therapeutics
Post-Op Complication, Skin Flap Necrosis
Quantifying the Venous Congestion Curve of a Tissue Oximetry Device
The purpose of this research study is to measure rate of decline and pattern of tissue oxygenation using the device, ViOptix T.Ox. ViOptix probes will be secured to the arm and hand.
- Trial name
- NCT05592145
- Testing
- ViOptix
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Crohn's Disease
Infliximab for the Prevention of Recurrent Crohn's Disease After Surgery
A randomized, placebo-controlled pilot study to determine endoscopic recurrence of Crohn's disease 12 months after curative, resective ileal or ileocolonic surgery in patients receiving post-operative infliximab or placebo
- Trial name
- NCT00688636
- Testing
- infliximab
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pittsburgh
Endometrial Cancer
The UPPROACH (Upfront Intensity Modulated Proton Beam Therapy) Approach
A phase 2 study with the primary objective of testing treatment compliance of Upfront Intensity Modulated Proton Beam Therapy (IMPT) and Concurrent Chemotherapy (UPPROACH) for Post-operative Treatment in Loco-regionally Advanced…
- Trial name
- NCT04527900
- Testing
- carboplatin and paclitaxel, pelvic IMPT (Intensity Modulated Proton Therapy)
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of Maryland, Baltimore
Postoperative Nausea and Vomiting
Postoperative Nausea and Vomiting: Ramosetron Plus Aprepitant vs Palonosetron Plus Aprepitant
The purpose of this study was to compare the antiemetic efficacy of aprepitant plus palonosetron versus aprepitant plus ramosetron in high risk patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT02597907
- Testing
- aprepitant, palonosetron, Ramosetron
- Volunteers
- 88 people
- Sponsor
- Kyungpook National University Hospital
Endometrial Diseases, Pain, Postoperative
Transcutaneous Electrical Nerve Stimulation During Outpatient Endometrial Biopsy
The purpose of this study is to see whether transcutaneous electrical nerve stimulation (or TENS) reduces pain during an endometrial biopsy.
- Trial name
- NCT05472740
- Testing
- TENS 7000
- Where
- United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Duke University
Pain, Postoperative
Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients
This is a prospective, randomized, double-blinded, placebo controlled trial Potential subjects will be identified from the Pre-Surgical Anesthesia Clinic visit.
- Trial name
- IV APAP SF (NCT01394718)
- Testing
- Intravenous Acetaminophen
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Children's Hospital of Philadelphia
Laminectomy, Post-laminectomy Syndrome
Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Traditionally, pain relief through spinal cord stimulation has been associated with the appearance of paresthesia in the affected area.
- Conditions
- Laminectomy, Post-laminectomy Syndrome, Spinal Cord Syndrome, Failed Back Surgery Syndrome
- Trial name
- NCT03702010
- Testing
- spinal cord stimulation conventional, spinal cord stimulation experimental
- Where
- 2 sites in Spain
- Volunteers
- 27 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
TSA, Bruise
Natural History of Pain After Shoulder Arthroplasty Conducted With Multimodal Analgesia
This study aims to identify the timeline of pain following total shoulder replacement with the goal of developing data for a subsequent randomized trial.
- Conditions
- TSA, Bruise, Pain, Postoperative
- Trial name
- TSA (NCT03021096)
- Testing
- Surveys
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis, Knee
Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
This study will evaluate the use of a local injection around the knee (periarticular) during total knee replacement (TKR) surgery to see if it reduces postoperative pain levels.
- Trial name
- NCT02570503
- Testing
- Ropivacaine, Ketorolac, Clonidine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Infection, Spinal Injuries
The Value of Home Chlorhexidine Pre-Surgical Wash Before Spine Surgery
The study team hypothesizes that at-home cleansing of the surgical site with chlorhexidine wipes provide no added benefit to decreasing microbial activity or preventing surgical site infections.
- Trial name
- NCT02767427
- Testing
- Chlorhexidine Wipes, No intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Meniscus Disorder, Meniscus, Torn Tibial
Blood Flow Restriction After Meniscus Repair
The purpose of this study is to evaluate post-operative outcomes after meniscus surgery in participants undergoing blood flow restriction training as a rehabilitative adjunct compared to those with standard rehabilitation.
- Conditions
- Meniscus Disorder, Meniscus, Torn Tibial, Meniscus Lesion, Meniscus Tear, Tibial
- Trial name
- NCT04436523
- Testing
- Blood flow restriction (Delfi Personalized Tourniquet System), Standard rehabilitation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Postoperative Dental Pain
A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo
Researchers are looking for a better way to relieve pain in people, such as after dental surgery. Participants in this study, have had 3 or 4 third molars (cheek teeth) removed and subsequently have moderate to severe tooth pain.
- Trial name
- NCT05485805
- Testing
- Naproxen sodium and caffeine (BAY2880376), Naproxen sodium (Aleve), Caffeine
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Bayer
Obesity
Effect of Single Dose Ketamine and Magnesium on Postoperative Pain in Patients Undergoing Bariatric Surgery
Opioid sparing analgesia is extremely important in the post-operative obese population. With more and more obese patients entering the operating room a multi-modal approach to analgesia is crucial.
- Trial name
- NCT02334059
- Testing
- Ketamine, Ketamine plus magnesium
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Milton S. Hershey Medical Center
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