Clinical trials: Post-Stroke Chronic Aphasia
Stroke
Transcranial Direct Current Stimulation for Post-Stroke Aphasia
This is a randomized, crossover design trial that will compare how anodal transcranial direct current stimulation (tDCS) versus sham tDCS administered during multiple sessions of scripting therapy affects the acquisition and…
- Trial name
- NCT02461355
- Testing
- Aphasia therapy, Anodal tDCS
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Columbia University
Aphasia, Chronic Stroke
Transcutaneous Vagus Nerve Stimulation in Aphasia After Stroke
Aphasia is an acquired language disorder. Stroke is the most common cause of aphasia, which affects 30% of stroke survivors. Speech and Language Therapy (SLT) can help people with aphasia but it may not be provided at the…
- Trial name
- TRANSLATE (NCT06403475)
- Testing
- Transcutaneous Vagus Nerve Stimulation, Computer Based Speech and Language Therapy (Step by Step)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Post Stroke Aphasia
Effect of High Frequency Transcranial Magnetic Stimulation on Recovery of Chronic Post-Stroke Aphasia
high frequency excitatory rTMS applied over the dominant hemisphere in chronic post stroke aphasic patients to help the restoration of function by the left hemisphere
- Trial name
- NCT04708197
- Testing
- rTMS (repetitive transcranial magnetic stimulation )
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Aphasia, Language
tDCS as an Adjuvant to Intensive Speech Therapy for Chronic Post Stroke Aphasia
The purpose of this study is to determine if transcranial direct current stimulation (tDCS) in conjunction with intensive speech therapy will improve sentence production and word retrieval in individuals with chronic post stroke…
- Trial name
- NCT02801864
- Testing
- Real tDCS, Intensive Speech Therapy
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Austin Speech Labs
Aphasia, Post-stroke
Transcranial Direct Current Stimulation to Enhance Training Effectiveness in Chronic Post-Stroke Aphasia
The aim of the study is to investigate whether intensive speech-language therapy (SLT) combined with anodal transcranial direct current stimulation (tDCS) leads to better communication performance than SLT combined with placebo…
- Trial name
- NCT03930121
- Testing
- Anodal transcranial direct current stimulation (tDCS) combined with speech-language therapy (SLT, including naming therapy and communicative-pragmatic therapy)
- Where
- 19 sites in Germany
- Volunteers
- 130 people
- Sponsor
- University Medicine Greifswald
Aphasia, Stroke
Tablet-based Aphasia Therapy in the Chronic Phase
Aphasia is one of the most common and disabling disorders following stroke, in many cases resolving in long-term deficits. There is evidence that intensive aphasia therapy is effective for language recovery, even in the chronic…
- Trial name
- NCT03622411
- Testing
- speech app, brain games, aphasia therapy
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University Hospital, Ghent
Aphasia
Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia
This study aims to determine whether transcranial direct current stimulation (tDCS) paired with speech-language therapy is more beneficial than speech-language therapy alone in acute and chronic post-stroke aphasia.
- Trial name
- NCT02622945
- Testing
- Active tDCS plus Speech-Language Therapy
- Where
- United States
- Sponsor
- Johns Hopkins University
Aphasia, Stroke
Levetiracetam (Keppra) to Improve Chronic Aphasia in Post-stroke Patients.
The study investigates the possibility that levetiracetam may improve the symptoms of chronic post-stroke aphasia.
- Trial name
- NCT00227461
- Testing
- Wait first, then levetiracetam, Levetiracetam first, then wait
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Kessler Foundation
Aphasia
Effect of Community Choir Singing in People With Chronic Post-stroke Aphasia
The goal of this randomized controled trial is to test the effects of assigning people with chronic post-stroke aphasia to 12 weekly choir sessions, compared to usual care.
- Trial name
- NCT06368323
- Testing
- Choir singing, Usual care
- Where
- 4 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- University of Ottawa
Stroke, Aphasia
Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions.
- Trial name
- AphasiatDCS (NCT04432883)
- Testing
- Active Comparator: Experimental: Active cathodal tDCS + language training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of New Mexico
Aphasia, Stroke
Brain Correlates of Multimodal Rehabilitation in Chronic Post-stroke Aphasia
Post-stroke aphasia (PSA), the partial or total loss of the ability to produce and/or understand language associated with stroke, is a highly prevalent and disabling disorder that negatively impacts the personal, social and…
- Trial name
- NCT04134416
- Testing
- Donepezil, Intensive-Language Action Therapy, Transcranial direct current stimulation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Malaga
Stroke, Ischemic Stroke
Detecting and Predicting Post-stroke Cognitive Impairment Using the Oxford Cognitive Screen
Cognitive problems are common after a stroke and must be identified early so that rehabilitation can be initiated to improve outcome.
- Conditions
- Stroke, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral, Cognitive Dysfunction
- Trial name
- OCS-PRECISE (NCT07897916)
- Where
- 2 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- University of Copenhagen
Stroke, Aphasia Following Cerebral Infarction
Combined Aphasia and Robot-Assisted Arm Treatment for Chronic Stroke Survivors
The goal of this clinical trial is to learn if a program that combines language and arm treatment can improve language and movement problems in people with chronic stroke.
- Conditions
- Stroke, Aphasia Following Cerebral Infarction, Hemiparesis After Stroke
- Trial name
- CARAT (NCT07000019)
- Testing
- CARAT: combined aphasia and robot-assisted arm therapy, Robot-assisted arm therapy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- New York Medical College
Aphasia
Speeded Anomia Treatment in Chronic Post-stroke Aphasia
The main aim of the study is to investigate the effect of a novel, speeded anomia therapy (Conroy et al., 2018) in a large population of patients with chronic post-stroke aphasia.
- Trial name
- NCT05512884
- Testing
- Speeded anomia therapy
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Cambridge
Aphasia, Language
Phonological Treatment Paired With Intensive Speech Therapy Promotes Reading Recovery in Chronic Aphasia
Participants will receive either intensive phonology or semantic feature analysis treatment for 16 weeks to improve naming, reading, and writing in individuals with chronic post-stroke aphasia.
- Trial name
- NCT02799017
- Testing
- Intensive Phonology Treatment, Intensive SFA Treatment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Austin Speech Labs
Aphasia, Acquired, Speech Therapy
Anomia Therapy and Executive Function Training in Chronic Post-stroke Aphasia: Pilot Study of Multidimensional Effects
The goal of this clinical trial is to measure the effects of a speech therapy protocol combining anomia therapy and executive function training on naming and discourse in people with chronic aphasia, and to study the related…
- Trial name
- ATAC2PILOT (NCT06712225)
- Testing
- Anomia therapy: semantic feature analysis and phonological components analysis;, Executive function training: computerized equipment
- Volunteers
- 8 people
- Sponsor
- University Hospital, Montpellier
Aphasia, Chronic Stroke
A Trial Investigating Telerehabilitation as an add-on to Face-to-face Speech and Language Therapy in Post-stroke Aphasia.
The aim of this study is to investigate the effects of high-frequency short duration tablet-based speech and language therapy (teleSLT) mixed with cognitive training (teleCT) in chronic stroke patients.
- Conditions
- Aphasia, Chronic Stroke, Post Stroke Seizure
- Trial name
- NCT03228264
- Testing
- teleSLT, teleCT
- Where
- 2 sites in Switzerland
- Volunteers
- 21 people
- Sponsor
- University of Bern
Aphasia Following Cerebral Infarction, Aphasia Following Nontraumatic Intracerebral Hemorrhage
TDCS and Aphasia Therapy in the Chronic Phase After Stroke
This study evaluates the neuromodulatory effect of combined tDCS and aphasia therapy in patients in the chronic phase after stroke.
- Trial name
- NCT03305614
- Testing
- tDCS, Aphasia therapy
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Ghent
Brain Injury, Vascular, Aphasia
Treatment of Grammatical Time Marking in Post-Stroke Aphasia
The study aims to assess an individual or self-administered computer therapy's effectiveness in grammatical time marking. The main objective is to examine whether the therapy improves grammatical time marking of inflected verbs…
- Conditions
- Brain Injury, Vascular, Aphasia, Stroke
- Trial name
- NCT05656638
- Testing
- Speech and language therapy
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- University of Neuchatel
Anomia, Post-stroke Aphasia
Executive Training and Anomia Therapy in Chronic Post-stroke Aphasia
Aphasia is a devastating acquired language impairment mainly caused by stroke, in which anomia is a quintessential clinical feature.
- Trial name
- ETAT PSA (NCT05101408)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Montpellier