Clinical trials: Post-Stroke Spasticity
Post-Stroke Spasticity
A Pilot Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368, a FAAH/MAGL Inhibitor, in Participants With Post-Stroke Spasticity (The STIPS Study)
The goal of this clinical trial is to learn if the drug BMS-986368 works to treat post stroke spasticity in adults who have had a stroke.
- Trial name
- STIPS (NCT07704840)
- Testing
- Administration of BMS-986368
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Alberto Esquenazi
Stroke, Post-Stroke Spasticity
ESTIM-UL: FES for Upper Limb Recovery After Stroke
Stroke is a leading cause of long-term disability, frequently resulting in impaired upper limb motor function and spasticity. Although Botulinum Toxin Type A (BoNT-A) is effective in reducing focal spasticity, functional recovery…
- Conditions
- Stroke, Post-Stroke Spasticity, Post-Stroke Hemiparesis
- Trial name
- ESTIM-UL (NCT07513714)
- Testing
- Functional Electrical Stimulation (FES), Conventional Rehabilitation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Foggia
Spasticity Post Stroke
Spinal Cord Stimulation for Poststroke Spasticity
The goal of this clinical trial is to learn whether spinal cord stimulation (SCS) is effective in treating post-stroke spasticity in adults. It will also evaluate the safety of the implanted SCS system.
- Trial name
- SCS-PSS (NCT07744659)
- Testing
- Active spinal cord stimulation
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Post-Stroke Spasticity, Spastic Equinovarus Foot
Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injection in Patients With Post-Stroke Spastic Equinus/Equinovarus Foot: A Randomized Clinical Trial
Spastic equinovarus foot is the most common lower limb motor impairment after stroke and has a significant impact on gait, mobility, and quality of life.
- Trial name
- NCT07758322
- Testing
- Botulinum toxin type A, Focal Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- María Belén Martínez Luna
Stroke, Post Stroke Upper Limb Spasticity
Effects of Focal Muscle Vibration Versus Whole Upper Limb Vibration in Post-Stroke Patients
This study contributes to the growing body of knowledge on rehabilitation strategies for post-stroke patients, specifically focusing on the efficacy of vibration therapy modalities.
- Trial name
- NCT07340034
- Testing
- Focal muscle vibration through focal muscle vibrator along with conventional neurorehabilitation, Upper limb vibration through whole body vibrator along with conventional neurorehabilitation
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Stroke, Post-stroke Spasticity of the Lower Limb
Extracorporeal Shock Wave Therapy in Botulinum Toxin-Treated Patients With Post-Stroke Ankle Plantar Flexor Spasticity
The goal of this clinical trial is to learn if radial Extracorporeal Shock Wave Therapy (rESWT) is effective in reducing ankle plantar flexor spasticity and improving walking functions in stroke patients who have already received…
- Conditions
- Stroke, Post-stroke Spasticity of the Lower Limb, Post-Stroke Spasticity, Spasticity of the Plantar Flexors
- Trial name
- NCT07695038
- Testing
- Radial Extracorporeal Shock Wave Therapy (rESWT), Conventional Physical Therapy and Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Pamukkale University
Post Stroke Spasticity
Effect of TENS on Spasticity
The purpose of this clinical trial is to evaluate whether Transcutaneous Electrical Nerve Stimulation (TENS) is effective in reducing spasticity in adults with post-stroke spasticity.
- Trial name
- NCT07669649
- Testing
- Transcutaneous electrical nerve stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people
- Sponsor
- Izmir Katip Celebi University
Post-Stroke Spasticity
Effect of NMES on Spasticity
The goal of this clinical trial is to learn if neuromuscular electrical stimulation (NMES) works to treat spasticity in adult patients with spasticity related to stroke.
- Trial name
- NCT07617311
- Testing
- Neuromuscular electrical stimulation (NMES)
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people
- Sponsor
- Izmir Katip Celebi University
Post-stroke Spasticity of the Upper Limb
TMS AND BOTULINUM TOXIN IN POST-STROKE UPPER LIMB SPASTICITY
Post-stroke upper limb spasticity is an important condition that negatively affects motor recovery, upper limb functions, and activities of daily living.
- Trial name
- TMS (NCT07624149)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Continuous Theta Burst Stimulation (cTBS)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Asya ÖZCAN KAVCI
Post-stroke Spasticity
Validity and Inter-rater Reliability for Early Recognition of Spasticity Using the Decision Tree Tool
The aim of this study is to investigate the validity and Inter-rater reliability for early recognition of spasticity by nurses and physiotherapists using the decision tree tool.
- Trial name
- I-REFER (NCT06381999)
- Where
- Austria
- Volunteers
- 70 people
- Sponsor
- Merz Therapeutics GmbH
Stroke, Post-Stroke Spasticity
Effect of Extracorporeal Shock Wave Therapy on Spasticity and Mobility in Stroke Patients
This study aims to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in individuals with lower limb spasticity following stroke.
- Conditions
- Stroke, Post-Stroke Spasticity, Lower Limb Spasticity
- Trial name
- ESWT-STROKE (NCT07523243)
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Volunteers
- 85 people
- Sponsor
- Istanbul Medipol University Hospital
Stroke, Upper Extremity Dysfunction
REHABOTICS: Physiotherapy for Hand Spasticity After Stroke Using Robotics and AR Serious Games
Rehabotics is a comprehensive rehabilitation system designed to deliver individualized upper-limb therapy for patients with motor impairments, particularly after stroke.
- Conditions
- Stroke, Upper Extremity Dysfunction, Spasticity Post Stroke
- Trial name
- NCT07468149
- Testing
- Rehabotics Physiotherapy
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Pantelis Syringas
Post Stroke Spastic Hemiplegia
Overlooked Barrier To Discontinuing Bont-A Therapy
This study aims to evaluate patient adherence to botulinum toxin (BoNT-A) treatment and identify the factors contributing to its discontinuation.
- Trial name
- NCT07422428
- Testing
- provide information by phone
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Suleyman Demirel University
Post-stroke Shoulder Pain,Rotator Cuff Tendonitis,Shoulder Spasticity
Shockwave and Cryoflow for Shoulder Pain After Stroke
This study aims to find out whether combining two physical therapy treatments - Extracorporeal Shockwave Therapy and Cryoflow Therapy - can help reduce shoulder pain and improve function in patients who have developed rotator…
- Trial name
- SW-CF-STROKE (NCT07196267)
- Testing
- Extracorporeal Shockwave Therapy, Cryoflow Therapy, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- MTI University
Stroke, Spasticity
Static Versus Dynamic Splints for Wrist Spasticity in Stroke Patients
The goal of this clinical trial is to evaluate whether different types of wrist-hand splints can reduce wrist flexor spasticity in subacute hemiplegic stroke patients.
- Conditions
- Stroke, Spasticity, Hemiplegia, Post Stroke Recovery
- Trial name
- NCT07301606
- Testing
- Static Wrist-Hand Splint, Dynamic Wrist-Hand Splint
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- University of Lahore
Upper Limb Spasticity Post-Stroke
Phase 1 Trial of JTM201 in Subjects With Post-stroke Upper Limb Spasticity
Phase 1 trial to evaluate the safety and efficacy of JTM201 compared with 'Botox® Inj.' in subjects with post-stroke upper limb spasticity
- Trial name
- NCT07292025
- Testing
- JTM201 in normal saline, BOTOX 100U in normal saline
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Jetema Co., Ltd.
Post Stroke Spasticity, Dystonia
Deep Anterior Cerebellar Stimulation in Treatment of Poststroke Spasticity and Motor Function Impairment.
The aim of this clinical trial is to determine whether deep brain stimulation (DBS) interventions improve rehabilitation and functional recovery in patients with post-stroke spasticity who meet the other inclusion criteria listed…
- Trial name
- NCT07190092
- Testing
- Deep brain stimulation electrode implantation with an electrode target in the dentate nucleus
- Where
- Poland
- Volunteers
- 12 people
- Sponsor
- Jan Biziel University Hospital No 2 in Bydgoszcz
Post-Stroke Chronic Upper Limb Spasticity
Effectiveness and Safety of SMART [Spastic Muscle Palpation by Anatomic Landscape for BoNT-A (Botulinumtoxin-A) Injection to Reduce Muscle Tone] BoNT-A Therapy With Dysport® in Patients With Post-stroke Chronic Upper Limb Spasticity (ULS) in Real-life Setting.
The purpose of this study is to collect data for Dysport® SMART BoNT-A therapy usage in an office-based setting in post-stroke participants with chronic (> 6 months) focal Upper Limb Spasticity who have been under stable oral…
- Trial name
- SMART-NIS (NCT05224349)
- Where
- 31 sites in Germany
- Volunteers
- 121 people
- Sponsor
- Ipsen
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Spasticity, Post-Stroke
The Effect of Low-Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Stroke Patients
In this study, we aimed to demonstrate the effects of 1 Hz rTMS applied to the contralesional hemisphere on upper extremity spasticity, spinal excitability, and additionally on motor recovery in stroke patients in the chronic…
- Trial name
- NCT06889922
- Testing
- Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent