Clinical trials: Post-Tonsillectomy
Peri-tonsillar Analgesic Infiltration, Tonsillectomy
Tramadol Versus Lidocaine Infiltration for Tonsillectomy
The investigators postulate that the use of pre-incisional peritonsillar infiltration of tramadol or lidocaine reduces both the inflammatory response and postoperative analgesic consumption, without harmful effects.
- Conditions
- Peri-tonsillar Analgesic Infiltration, Tonsillectomy, Postoperative Pain, Inflammatory Response
- Trial name
- NCT01552096
- Testing
- peritonsillar infiltration
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Pain Management
Pain Management in Pediatric Adenotonsillectomy
Tonsillectomy is considered one of the most frequent minor surgeries conducted on a day-case basis on children, and usually associated with pain and sore throat.
- Trial name
- AZU (NCT05928520)
- Testing
- Tramadol 5%, Lidocaine 2%
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Tonsillectomy
EXPAREL Post-tonsillectomy Clinical Trial
Tonsillectomy is one of the most commonly performed surgical procedures in the United States. The primary indications for tonsillectomy in the adult population include recurrent pharyngitis, chronic tonsillitis, and obstructive…
- Trial name
- EXPCT (NCT03420638)
- Testing
- Adjunct Exparel (bupivacaine liposome suspension 1.3%), Standard Care
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Paul Hoff
Adenotonsillar Hypertrophy
Remiazolam vs Propofol Total Intravenous Anesthesia on Postoperative Neurodevelopment After General Anesthesia in Children
The goal of this clinical trial is to learn the effects of remimazolam for total intravenous anesthesia on the neurodevelopment of children aged 3-6 years who underwent tonsil/adenoid removal surgery after general anesthesia when…
- Trial name
- REMPPON (NCT07194109)
- Testing
- Remimazolam based total intravenous anesthesia, Propofol based general anesthesia
- Volunteers
- 558 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Post-Tonsillectomy Bleeding
The Impact of Tonsillectomy Techniques on Secondary Tonsillectomy Bleeding
Post-tonsillectomy hemorrhage (PTH) is one of the most common and potentially life-threatening complications of tonsillectomy. Secondary PTH (Bleeding occurring >24 hours post-operatively) is of particular clinical significance.
- Trial name
- NCT07763704
- Volunteers
- 100 people
- Sponsor
- Assiut University
Surgery, Stress
The Effects of Healing Touch on Post Operative Pediatric Patients
The goal of this study is to assess the benefits of Healing Touch, an energy based therapy on post-operative discomfort and the rate of recovery in children.
- Conditions
- Surgery, Stress, Pain, Children
- Trial name
- NCT01738308
- Testing
- Healing Touch
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Tonsillitis
Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea
The purpose of this study is to determine if auricular acupuncture significantly reduces post-operative pain in comparison to the standard of care.
- Trial name
- BFA (NCT02571075)
- Testing
- Auricular acupuncture
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Preoperative Gabapentin for Post-tonsillectomy Pain in Children
The typical post-operative course for children following surgical removal of their tonsils and adenoids can be challenging, especially for pain control.
- Trial name
- NCT01707420
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Colorado, Denver
Tonsillectomy
Cold Steel Versus "Hot" BiZact Tonsillectomy; Comparing Post Tonsillectomy Morbidity
Tonsillectomy, with or without adenoidectomy, in both children and adults is worldwide one of the most commonly performed surgical procedures in otorhinolaryngology, and the number is increasing.
- Trial name
- NCT05270109
- Testing
- BiZact, Cold Steel
- Where
- Denmark
- Volunteers
- 1,250 people
- Sponsor
- Line Schiøtt Nissen
Obstructive Sleep Disorder, Obstructive Sleep Apnea
Topical Microporous Polysaccharide Hemospheres Versus Electrocautery for Control of Pediatric Post-Tonsillectomy Bleeding
The ultimate goal of this work is to establish a method for control bleeding after tonsillectomy in awake children. Treatment of post-tonsillectomy bleeding in children typically requires general anesthesia with currently used…
- Conditions
- Obstructive Sleep Disorder, Obstructive Sleep Apnea, Tonsillar Hypertrophy
- Trial name
- NCT00945412
- Testing
- Micropolysaccharide Hemospheres (Arista), Electrocautery (Monopolar suction cautery)
- Where
- United States
- Sponsor
- Massachusetts Eye and Ear Infirmary
Postoperative Pain, Acute Pain
Pharmacokinetic, Efficacy and Safety Study of Tapentadol Oral Solution in Children With Postoperative Pain
To find out if a drug called tapentadol administered by mouth safely relieves pain in children. Look at the amount of tapentadol in the blood after a single oral dose.
- Trial name
- NCT01729728
- Testing
- Tapentadol
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Grünenthal GmbH
Postoperative Pain
Percutaneous Peristyloid Glossopharyngeal Block After Tonsillectomy
Adenotonsillectomy surgery in paediatrics is commonly managed as an ambulatory surgery. This may be attributed to the use of the electro-dissection surgical technique that decreases the incidence of immediate postoperative…
- Trial name
- NCT04970680
- Testing
- glossopharyngeal nerve block
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Suez Canal University
Tonsillectomy
Postoperative Oral Corticosteroids Following Tonsillectomy
Tonsillectomy is one of the most common surgical procedures in the United States, and post-operative pain management is a challenge for otolaryngologists.
- Trial name
- NCT03352115
- Testing
- Prednisolone
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Tonsillectomy, Hemorrhage
HemORL: Monocentric, Prospective, Comparative Study on the Use of a Haemostatic Vacuum Device During Tonsillectomy in Children
The long-term objective of this study is to prove: the equivalence of the number of post-operation hemorrhages, and maybe a decrease of the number of secondary hemorrhages the decrease of pain and quicker re-feeding an easier…
- Conditions
- Tonsillectomy, Hemorrhage, Postoperative Complications
- Trial name
- HemORL (NCT01904461)
- Testing
- Vacuum device, Conventional surgery
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Grenoble
Tonsillitis, Airway Obstruction
Acetaminophen's Efficacy For Post-operative Pain
The purpose of this study is to compare IV acetaminophen to oral acetaminophen for pain control in children undergoing tonsillectomy with or without adenoidectomy.
- Conditions
- Tonsillitis, Airway Obstruction, Difficulty Swallowing
- Trial name
- NCT01721486
- Testing
- IV acetaminophen, PO acetaminophen
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Kaveh Aslani, MD
Post Tonsillectomy Pain, Post Operative Analgesia
Transnasal Sphenopalatine Ganglion Block for Postoperative Pain and Recovery in Tonsillectomy (TONwoPA)
The aim of this clinical trial is to evaluate the effectiveness of transnasal transmucosal sphenopalatine ganglion block in reducing post-tonsillectomy pain.
- Conditions
- Post Tonsillectomy Pain, Post Operative Analgesia, Opioid Consumption, Sphenopalatine Ganglion Block
- Trial name
- TONwoPA (NCT07370129)
- Testing
- Transnasal Transmucosal Sphenopalatine Ganglion Block, Lidocaine %5, Saline (0.9% NaCl)
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ankara University
Postoperative Nausea and Vomiting
Dexamethasone Versus Local Infiltration Technique for Tonsillectomy in Children
Tonsillectomy is one of the most frequent surgical operations performed in children [1-4]. It is usually associated with postoperative nausea and vomiting (PONV) with an incidence ranging from 23% to 73% [2].
- Trial name
- NCT02355678
- Testing
- dexamethasone, Local anesthetic infiltration, General anesthesia
- Where
- Lebanon
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Tonsil Disease, Surgical Wound
Effect of Pre-operative Oral Hydration on Post-operative Pain and Nausea in Adults Undergoing Tonsillectomy
Tonsillectomy is commonly described as one of the most painful procedures that an adult can undergo. This study's aim is to evaluate if pre-operative oral hydration has an impact in reducing post-operative pain, nausea and…
- Conditions
- Tonsil Disease, Surgical Wound, Pain, Postoperative
- Trial name
- NCT05507918
- Testing
- Oral water and clear liquids
- Sponsor
- Corewell Health East
Hemorrhage, Pain
Effect of Tonsillar Pillar Closure on Postoperative Pain and Bleeding Risk After Tonsillectomy
The purpose of this study is to determine if closing the tonsil fossa after tonsillectomy leads to less pain and bleeding risk than leaving it open to heal by secondary intention.
- Trial name
- NCT00394849
- Testing
- suture one tonsillar fossa
- Where
- United States
- Volunteers
- 763 people, healthy volunteers welcome
- Sponsor
- Indiana University
Emergence Agitation, Emergence Delirium
Effect of Nebulized Lignocaine on Emergence Agitation After Sevoflurane Anesthesia in Pediatric Patients Undergoing Tonsillectomy
Emergence agitation is a frequent recovery complication in young children following general anesthesia with sevoflurane. It is characterized by confusion, crying, disorientation, and non-purposeful thrashing during early…
- Conditions
- Emergence Agitation, Emergence Delirium, Postoperative Pain
- Trial name
- NCT07871266
- Testing
- Lidocaine, 0.9% Normal Saline
- Volunteers
- 60 people
- Sponsor
- Assiut University