Clinical trials: Post-cesarean Pain
Postoperative Pain
Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management
The ability to predict pain and then apply modified treatment protocols has been limited. Current practice is for physicians to select standard post-operative pain treatment protocols without patient consultation.
- Trial name
- NCT02605187
- Testing
- No choice given, Choice given, Ibuprofen
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Stanford University
Pain, Postoperative
Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
This study will compare IV (intravenous) versus oral (PO) acetaminophen for postoperative pain after scheduled, elective Cesarean delivery.
- Trial name
- NCT02487303
- Testing
- Acetaminophen Intravenous, Acetaminophen Oral
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pain, Postoperative, Anxiety
Healing Touch After Cesarean
Pain and anxiety are the most common complications after cesarean birth, and impair the mother's ability to optimally care for herself and her newborn.
- Conditions
- Pain, Postoperative, Anxiety, Postpartum Complication
- Trial name
- NCT05053360
- Testing
- Healing Touch, Control
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Inova Health Care Services
Pain, Postoperative
Liposomal Bupivacaine at Cesarean Delivery to Decrease Post-operative Pain
This is a randomized controlled trial to test whether the use of liposomal bupivacaine at the time of cesarean delivery may decrease post-operative pain scores.
- Trial name
- NCT02959996
- Testing
- Liposomal bupivacaine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Labor Pain, Complications; Cesarean Section
Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)
To compare the effects of epidural versus combined spinal and epidural (CSE) anesthesia on the success of Trial of Labor After Cesarean (TOLAC).
- Conditions
- Labor Pain, Complications; Cesarean Section, Pregnancy
- Trial name
- NCT02105558
- Testing
- Epidural anesthesia, Combined spinal and epidural anesthesia
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain
Ropivacaine Transversus Abdominis Plane Blocks for Cesarean Section Analgesia
With this research the investigators hope to determine the lowest dose of ropivacaine used in transversus abdominis plane (TAP) blocks that can effectively treat pain in women after cesarean section (c-section).
- Trial name
- TAPROPI (NCT02893423)
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Postoperative Pain
Intrathecal Morphine for Cesarean Delivery
This is a randomized double blinded non-inferiority study comparing the duration of pain relief when patients receive one of three doses of spinal morphine.
- Trial name
- NCT05069012
- Testing
- Morphine Sulfate
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Beth Israel Deaconess Medical Center
Labor Pain, Post-cesarean Delivery
Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia
Pharmacogenetics has allowed clinicians to identify associations between an individual's genetic profile and his/her response to drugs.
- Trial name
- NCT00418015
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Postoperative
ITM + Bupivacaine QLB vs. ITM + Sham Saline QLB for Cesarean Delivery Pain
Comparison of standard post-operative cesarean surgery pain management with regional post-op pain control.
- Trial name
- qlcsection (NCT03261193)
- Testing
- ITM + Bupivacaine QLB
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Nicholas Schott
Pain, Postoperative, Postoperative Nausea and Vomiting
Dexamethasone for Post-cesarean Delivery Pain
The purpose of this study is to compare post-cesarean section consumption of pain medication between two groups of patients undergoing scheduled cesarean section at term gestation who receive a single-dose of intraoperative…
- Trial name
- NCT01812057
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Duke University
Pain, Postoperative, Opioid Use
Management Of Pain After Cesarean Trial
This is a double blinded randomized controlled trial to test the efficacy of a combination of acetaminophen and ibuprofen administered to patients on schedule compared to ibuprofen alone on the patient's reported pain score on…
- Trial name
- MOPAC (NCT03929640)
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Milton S. Hershey Medical Center
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Pain, Postoperative
Post-operative Patient Positioning Device for Improvement of Post-Operative Pain
This paucity of evidence supporting or dissuading the use of postoperative abdominal support following cesarean section for the reduction of postoperative pain leaves important clinical questions unanswered.
- Trial name
- NCT04797637
- Testing
- ABBy® Adjustable Panniculus Retractor for Wound Care
- Where
- United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pain
Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section
For post-Cesarean analgesia, the investigators will compare the efficacy of single-shot epidural preservative free morphine with a continuous epidural fentanyl infusion.
- Trial name
- NCT01362998
- Testing
- Preservative free morphine, Fentanyl
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Goodman, Evan, M.D.
Pain, Postoperative
Post-Op Lidocaine Patch
Randomized control trial evaluating use of lidocaine vs placebo patch for post-operative cesarean incision pain.
- Trial name
- NCT03500211
- Testing
- Lidoderm 5 % Topical Patch
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Complications; Cesarean Section, Pregnancy
Mobius® Post-cesarean Pain Randomized Control Trial
The purpose of this study is to investigate whether the use of the Mobius® retractor decreased post-operative pain after cesarean section verses conventional retractor use.
- Trial name
- NCT00685932
- Testing
- Mobius Retractor
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Abbey Hardy-Fairbanks
Pain, Postoperative
The OBstetric Lidocaine Patch (OBLido) Trial
This study will be a single-center, single blind, randomized controlled trial. The study will be conducted at UnityPoint-Health Meriter Hospital under investigators from the University of Wisconsin-Madison.
- Trial name
- OBLido (NCT03810235)
- Testing
- Transdermal Lidocaine Patch
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Pregnancy Related, Opioid Use
Opioid Prescription After Cesarean Trial
Non-inferiority randomized trial of 5,500 women with a cesarean delivery randomized prior to discharge to either an individualized opioid prescription protocol (IOPP) that includes shared decision making or to a fixed opioid…
- Conditions
- Pregnancy Related, Opioid Use, Pain
- Trial name
- PACT (NCT04296396)
- Testing
- 0 to 20 tablets of oxycodone 5mg, Fixed opioid prescription
- Where
- 12 sites in United States
- Volunteers
- 5,521 people
- Sponsor
- The George Washington University Biostatistics Center
Pain, Referred
Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section
The purpose of this study is to determine if giving an injection of numbing medication at the incision at the end of cesarean will help control pain AFTER cesarean delivery.
- Trial name
- NCT03383588
- Testing
- Bupivacaine, Morphine, Fentanyl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Acute Pain, Cesarean Delivery
NSS-Bridge Device for Post-Cesarean Delivery Pain
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Trial name
- NCT03830307
- Testing
- NSS-2-Bridge
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS