Clinical trials: Post-operation Delirium
Postoperative Delirium, Postoperative Cognitive Dysfunction
Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool
This observational cohort study is designed to validate the CogCheck application as a risk prediction tool for postoperative delirium in patients undergoing cardiac surgery.
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Cognitive Decline, Cognitive Impairment
- Trial name
- CogCheck-Valid (NCT03360838)
- Testing
- CogCheck
- Where
- Switzerland
- Volunteers
- 475 people
- Sponsor
- University Hospital, Basel, Switzerland
Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Functional Recovery After Cardiac Surgery : Does Delirium and Calorie Intake Matter?
The aims of the cohort study is to describe the rates of 30-day surgical complication, functional decline, frailty and one-year mortality for patients experienced cardiac surgery and to delineate the trajectory of functional…
- Trial name
- NCT02212509
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Post Operative Cognitive Dysfunction
Ketamine and Postoperative Cognitive Dysfunction
Over 30 million patients require a major surgery annually in the US alone and more than half of them are performed in patients over 60 years of age.
- Trial name
- POCK (NCT02892916)
- Testing
- Ketamine
- Where
- France
- Volunteers
- 307 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Emergence Agitation
The Effect of Dexmedetomidine Versus Lidocaine on Emergence Agitation.
The effect of intravenous dexmedetomidine versus intravenous lidocaine on the emergence agitation after endoscopic sinus surgery.
- Trial name
- NCT07355049
- Testing
- Dexmedetomidine, Lidocaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Fayoum University
Emergence Agitation After Desflurane Anesthesia
Gabapentin Oral Solution in Decreasing Desflurane Associated Emergence Agitation
to study the effect of oral gabapentin (5 mg/kg) on emergence agitation after desflurane anesthesia in pediatrics undergoing starbismus surgery
- Trial name
- NCT03347916
- Testing
- Gabapentin Oral Solution [Neurontin]
- Where
- Kuwait
- Volunteers
- 75 people
- Sponsor
- Kuwait Specialized Eye Center
Postoperative Delirium, Postoperative Recovery in Elderly Patients
Recovery After Upper Extrimety Surgery
The goal of this randomized clinical trial is to determine whether Bispectral Index (BIS)-guided general anesthesia improves postoperative cognitive recovery and overall quality of recovery in adults undergoing elective hand or…
- Conditions
- Postoperative Delirium, Postoperative Recovery in Elderly Patients, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- Recovery (NCT07714928)
- Testing
- BIS-Guided General Anesthesia, Clinically Guided General Anesthesia
- Where
- Sweden
- Volunteers
- 112 people
- Sponsor
- Region Örebro County
Delirium, Critical Illness
Remimazolam vs Midazolam to Reduce Delirium in Adults ≥65 Undergoing CPB Valve Surgery
"Postoperative delirium is a common and serious complication following cardiac surgery, particularly among older adults who require intensive care.
- Conditions
- Delirium, Critical Illness, Aged, Cardiopulmonary Bypass
- Trial name
- NCT07265128
- Testing
- Midazolam, Remimazolam
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Yonsei University
Delirium, Femoral Fracture
Family Caregiver Role in Decreasing Delirium in Older Patients With Fractured Femur Using HELP Principles.
The Hospital Elder Life Program (HELP) has been shown to reduce delirium in hospitalized patients. In this study a family caregiver will apply the principles of the HELP program in a structured manner following training by a…
- Trial name
- FamHelp (NCT05321771)
- Testing
- Family caregiver application of HELP principles
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rambam Health Care Campus
Postoperative Delirium After On-pump Cardiac Surgery
Preoperative Transcranial Doppler as a Predictor for Delirium Following On-pump Cardiac Surgery
Postoperative delirium is an important problem in patients undergoing major cardiac surgery and associated with more complicated hospital course, increased hospital length of stay and total postoperative cost.
- Trial name
- NCT02478736
- Testing
- No actual intervention
- Where
- South Korea
- Volunteers
- 175 people
- Sponsor
- Yonsei University
Cardiovascular Surgery
Tranexamic Acid Dose and Confusion After Cardiac Surgery
Delirium is one of the most common complications after cardiac surgery and occurs with an incidence of 3 - 70%. Both predisposing factors (age, diabetes, severity of cardiac disease, atrial fibrillation) and precipitating factors…
- Trial name
- NCT05966012
- Testing
- Tranexamic acid
- Where
- United Kingdom
- Volunteers
- 5,000 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Delirium, Postoperative
Effectiveness of Delirium Care Protocol After Cardiac Surgery
This study was conducted as a quasi-experimental study to determine the effectiveness of the postoperative delirium prevention, diagnosis and intervention protocol in patients monitored in the intensive care unit after cardiac…
- Trial name
- NCT06268119
- Testing
- training nurses and caring for patients to prevent, diagnose, and intervene in postoperative delirium.
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Gonul Kara Soylemez
Postoperative Cognitive Dysfunction, Post Operative Delirium
Comparison Between the Effect of Dexmedetomidine _midazolam and ketamine_midazolam Combination
Postoperative cognitive dysfunction (POCD) is one of the most common complications after anesthesia, with a prevalence of approximately 12% and a higher prevalence of up to 41.4% in older surgical patients during the entire…
- Trial name
- NCT07074262
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Beni-Suef University
Delirium, Postoperative, Anesthesia
Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery
The goal of this clinical trial (Balanced-2 study) is to compare light to deep general anesthesia using widely available brain monitors, to see if 'light' anesthesia could reduce rates of delirium, cognitive decline, and…
- Conditions
- Delirium, Postoperative, Anesthesia, Surgery-Complications, Cognition Disorder
- Trial name
- Balanced-2 (NCT06268080)
- Testing
- Depth of anesthesia titration using pEEG
- Where
- 3 sites in New Zealand
- Volunteers
- 2,766 people
- Sponsor
- Auckland City Hospital
Post-operative Delirium
A Placebo Controlled Trial Of L-Tryptophan In Post-Operative Delirium
Post-operative delirium is a common and deleterious complication in elderly patients. The investigators have previously found lower levels of serum tryptophan in post-operative elderly patients who developed delirium in…
- Trial name
- NCT00865202
- Testing
- L-tryptophan supplementation
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- University of Colorado, Denver
Emergence Agitation, Pain
Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Emergence agitation (EA) occurs in up to 67% of pediatric patients after anesthesia for bilateral myringotomy tubes (BMT, "ear tubes").
- Trial name
- NCT01737593
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Emergence Delirium, Post-Operative Cognitive Dysfunction
Post Operative Cognitive Dysfunction and Delirium After Spinal Surgery
Aim of this trial is to define if Post-Operative Cognitive Dysfunction and Delirium, detected analyzing changes between pre-operative and post-operative Neurocognitive Test, relate to concentration of effector's site…
- Trial name
- NCT03950557
- Volunteers
- 200 people
- Sponsor
- University of Padova
Emergence Agitation
Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation
The goal of this clinical trial is to compare Propofol versus Dexmedetomidine in children undergoing squint surgery. The main question it aims to answer is: Which drug is more effective in preventing the appearance of Emergence…
- Trial name
- NCT06312618
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Delirium in Old Age
Erector Spinae Block and Incidence of Postoperative Delirium After Hip Fracture Surgeries
Postoperative pain is a significant risk factor for delirium. This clinical trial will search whether analgesia produced by erector spinae block in elderly patients undergoing hip fracture surgeries reduces delirium or not!
- Trial name
- NCT05819723
- Testing
- CAM score
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Delirium
Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery
This randomized double-blind parallel clinical study was conducted on 60 patients undergoing elective cardiac surgery under general anesthesia, at least 60 yr old, ASA I and II, 70-100 kg body weight and height 160-180 cm.
- Trial name
- NCT03078946
- Testing
- Dexmedetomidine Hydrochloride, Morphine and Midazolam
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Postoperative Delirium, Postoperative Cognitive Dysfunction
Bilateral Bispectral Index, Asymmetries and Post-operative Delirium
The primary objective of the study is to describe the value of interhemispheric asymmetry (ASYM), during the different intra- and peri-operative phases, in those patients who develop or do not develop post-operative delirium…
- Trial name
- DELBIS (NCT06761573)
- Testing
- Bilateral Bispetral Index Monitor will be applied on forehead of our patients, before surgery begins
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna